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The map label for this gene is luxO [H]

Identifier: 167623449

GI number: 167623449

Start: 1830631

End: 1832142

Strand: Direct

Name: luxO [H]

Synonym: Shal_1518

Alternate gene names: 167623449

Gene position: 1830631-1832142 (Clockwise)

Preceding gene: 167623448

Following gene: 167623450

Centisome position: 35.02

GC content: 44.71

Gene sequence:

>1512_bases
ATGGATATAACAAGCTCATTTACCGCATTATTAGTCGAAGATAGTATGTCGCTTGGGGCGCTTTATACCGAATACCTGCG
AGCAGATGGAGCACGAGTGACCCATGTTAATCATGGAGAAGATGCGTTAAATGAACTCAAACGTTGGCAACCCGATCTAT
TAGTGCTCGACATTCAACTGCCCGATATGTCTGGGATGGATATTTTGGAAACGGTACAGCAGCAATATCCTGATATCACT
GTCATTATGATCACCGCTCACGGCACAATTGATATCGCTGTCGATGCCATGCGTTCGGGGGCGTTCGATTTTCTAGTCAA
ACCTTTCGATGCAAAACGCCTTTCCATTACTGTTCGTAATGCCTTGAAGCAGCGTCAGCTTGTTAATCTAGTCGCAAAAT
ATGAGAGTAGTCTGCCCAAGCCTCACTATATGGGGTTTGTGGGGGAGTCGCTTGCGATGCAAACCGTTTATAAAACCATA
GATTGTGTGGCAAATAGTAAAGCTTCGGCATTTATTATTGGTGAAAGTGGGACAGGAAAAGAGGTGTGTGCTCATGCCAT
ACACAATGCGGGTAATCGCCATGATGGACCATTCGTTGCGTTAAATTGTGCTTCAATCCCTAAGGACTTGATTGAAAGTG
AAATTTTTGGTCACACTAAGGGAGCTTTTACTGGGGCGATAGCCAATAGAGATGGCGCGGCGACACGCGCACATAACGGT
ACGCTGTTTCTTGATGAGATCTGCGAAATGGATCTTGAGCTACAGAGTAAGTTGTTGCGCTTTATCCAAACGGGTGTGTT
TCAGCGCGTGGGGGGAACCAAAGAGGAAAAAGTGGACGTGAGGTTTGTGAGTGCAACCAATCGTATGCCATGGGATGAAG
TCAAAGCGGGACGCTTTAGAGAAGATCTGTTTTATCGCCTGCATGTGATCCCAATAGAATTACCCCCCCTAAGAATGCGA
GGCAAAGATATCTTACTGCTCGCTTCGAATTTACTCAAAGAATATAACAAGGAAGAGGGCAAGCGGTTTAAGGGGATTAG
CTGCGATGCTAAGCAATGTTTAAAATCTTATCAATGGCCTGGTAATGTTAGGCAGCTACAAAATGTTATTAGGCAGATAG
TGGTATTAAACGATGGCGAGTTAGTTGAGCTTGATATGCTACCGATACAAATGACGGCGACATCTGAGACGACTTTAGCG
AAGGTTTCCGAGCCTGTTCAACAAGACCAAAGCGTTTCTATCGCAGCCTCAAATTCGGCACCGGTTTCTTTTCTGGAGGG
GATCGAATCTGCTGGTTTTTCGGCAGATGAACATTTTCCAGCTGTAACGCCAGAGGCAAAGAGTGACGATATTGTGCCTT
TATGGCTAACAGAGAAACAGACAATAGAAAATGCAATAGCATTATGCAAGGGGAACGTACCTAAAGCCGCGGCACTATTA
GATATTAGTGCTTCGACAATTTATCGAAAGCGTCAAACTTGGGAAGAGTTAGAAAATAGCTTAAGCCACTAA

Upstream 100 bases:

>100_bases
AGACTAAACGCTATGCGCAAACGGCAAACCTGAGTTTAGCCTTTTGACATTGACCAAACTGCTATTAAGAGTAGTTTCAC
TACTAATAGGCTGGACTTAT

Downstream 100 bases:

>100_bases
GTTATTGGCCGCCAATACCATAGGTTATTCACTTTCTTATACTGATTGGAATTAATAGAGCTATGTTGATGAAAAGAGTA
GACTAACGGTCTACTCTTTT

Product: Fis family two component sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MDITSSFTALLVEDSMSLGALYTEYLRADGARVTHVNHGEDALNELKRWQPDLLVLDIQLPDMSGMDILETVQQQYPDIT
VIMITAHGTIDIAVDAMRSGAFDFLVKPFDAKRLSITVRNALKQRQLVNLVAKYESSLPKPHYMGFVGESLAMQTVYKTI
DCVANSKASAFIIGESGTGKEVCAHAIHNAGNRHDGPFVALNCASIPKDLIESEIFGHTKGAFTGAIANRDGAATRAHNG
TLFLDEICEMDLELQSKLLRFIQTGVFQRVGGTKEEKVDVRFVSATNRMPWDEVKAGRFREDLFYRLHVIPIELPPLRMR
GKDILLLASNLLKEYNKEEGKRFKGISCDAKQCLKSYQWPGNVRQLQNVIRQIVVLNDGELVELDMLPIQMTATSETTLA
KVSEPVQQDQSVSIAASNSAPVSFLEGIESAGFSADEHFPAVTPEAKSDDIVPLWLTEKQTIENAIALCKGNVPKAAALL
DISASTIYRKRQTWEELENSLSH

Sequences:

>Translated_503_residues
MDITSSFTALLVEDSMSLGALYTEYLRADGARVTHVNHGEDALNELKRWQPDLLVLDIQLPDMSGMDILETVQQQYPDIT
VIMITAHGTIDIAVDAMRSGAFDFLVKPFDAKRLSITVRNALKQRQLVNLVAKYESSLPKPHYMGFVGESLAMQTVYKTI
DCVANSKASAFIIGESGTGKEVCAHAIHNAGNRHDGPFVALNCASIPKDLIESEIFGHTKGAFTGAIANRDGAATRAHNG
TLFLDEICEMDLELQSKLLRFIQTGVFQRVGGTKEEKVDVRFVSATNRMPWDEVKAGRFREDLFYRLHVIPIELPPLRMR
GKDILLLASNLLKEYNKEEGKRFKGISCDAKQCLKSYQWPGNVRQLQNVIRQIVVLNDGELVELDMLPIQMTATSETTLA
KVSEPVQQDQSVSIAASNSAPVSFLEGIESAGFSADEHFPAVTPEAKSDDIVPLWLTEKQTIENAIALCKGNVPKAAALL
DISASTIYRKRQTWEELENSLSH
>Mature_503_residues
MDITSSFTALLVEDSMSLGALYTEYLRADGARVTHVNHGEDALNELKRWQPDLLVLDIQLPDMSGMDILETVQQQYPDIT
VIMITAHGTIDIAVDAMRSGAFDFLVKPFDAKRLSITVRNALKQRQLVNLVAKYESSLPKPHYMGFVGESLAMQTVYKTI
DCVANSKASAFIIGESGTGKEVCAHAIHNAGNRHDGPFVALNCASIPKDLIESEIFGHTKGAFTGAIANRDGAATRAHNG
TLFLDEICEMDLELQSKLLRFIQTGVFQRVGGTKEEKVDVRFVSATNRMPWDEVKAGRFREDLFYRLHVIPIELPPLRMR
GKDILLLASNLLKEYNKEEGKRFKGISCDAKQCLKSYQWPGNVRQLQNVIRQIVVLNDGELVELDMLPIQMTATSETTLA
KVSEPVQQDQSVSIAASNSAPVSFLEGIESAGFSADEHFPAVTPEAKSDDIVPLWLTEKQTIENAIALCKGNVPKAAALL
DISASTIYRKRQTWEELENSLSH

Specific function: Involved in the regulation of different processes depending on the cell density. Acts together with sigma-54 to repress, perhaps indirectly, some genes [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=383, Percent_Identity=41.77545691906, Blast_Score=301, Evalue=4e-83,
Organism=Escherichia coli, GI1790299, Length=406, Percent_Identity=41.3793103448276, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1790437, Length=481, Percent_Identity=37.006237006237, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1788905, Length=373, Percent_Identity=39.9463806970509, Blast_Score=265, Evalue=7e-72,
Organism=Escherichia coli, GI1789233, Length=361, Percent_Identity=39.3351800554017, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI87082117, Length=287, Percent_Identity=43.9024390243902, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI87082152, Length=231, Percent_Identity=50.6493506493506, Blast_Score=228, Evalue=9e-61,
Organism=Escherichia coli, GI1789087, Length=303, Percent_Identity=40.5940594059406, Blast_Score=221, Evalue=8e-59,
Organism=Escherichia coli, GI1786524, Length=314, Percent_Identity=37.8980891719745, Blast_Score=188, Evalue=8e-49,
Organism=Escherichia coli, GI1787583, Length=274, Percent_Identity=39.4160583941606, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI87081872, Length=230, Percent_Identity=41.7391304347826, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI87081858, Length=330, Percent_Identity=30.3030303030303, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1789828, Length=242, Percent_Identity=32.2314049586777, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786838, Length=127, Percent_Identity=33.0708661417323, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788394, Length=122, Percent_Identity=31.1475409836066, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082012, Length=122, Percent_Identity=36.8852459016393, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789809, Length=122, Percent_Identity=31.1475409836066, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786784, Length=126, Percent_Identity=31.7460317460317, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 55666; Mature: 55666

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDITSSFTALLVEDSMSLGALYTEYLRADGARVTHVNHGEDALNELKRWQPDLLVLDIQL
CCCCCCHHEEEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCEEEEEEEC
PDMSGMDILETVQQQYPDITVIMITAHGTIDIAVDAMRSGAFDFLVKPFDAKRLSITVRN
CCCCCHHHHHHHHHHCCCEEEEEEEECCEEEEEHHHHHCCCHHEEECCCCCCEEEEHHHH
ALKQRQLVNLVAKYESSLPKPHYMGFVGESLAMQTVYKTIDCVANSKASAFIIGESGTGK
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCH
EVCAHAIHNAGNRHDGPFVALNCASIPKDLIESEIFGHTKGAFTGAIANRDGAATRAHNG
HHHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCC
TLFLDEICEMDLELQSKLLRFIQTGVFQRVGGTKEEKVDVRFVSATNRMPWDEVKAGRFR
CEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHCCHHH
EDLFYRLHVIPIELPPLRMRGKDILLLASNLLKEYNKEEGKRFKGISCDAKQCLKSYQWP
HHHEEEEEEEEEECCCCCCCCCCCEEHHHHHHHHHCHHHCCEECCCCCCHHHHHHHCCCC
GNVRQLQNVIRQIVVLNDGELVELDMLPIQMTATSETTLAKVSEPVQQDQSVSIAASNSA
CCHHHHHHHHHHHEEECCCCEEEEEEEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCC
PVSFLEGIESAGFSADEHFPAVTPEAKSDDIVPLWLTEKQTIENAIALCKGNVPKAAALL
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHEE
DISASTIYRKRQTWEELENSLSH
ECHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDITSSFTALLVEDSMSLGALYTEYLRADGARVTHVNHGEDALNELKRWQPDLLVLDIQL
CCCCCCHHEEEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCEEEEEEEC
PDMSGMDILETVQQQYPDITVIMITAHGTIDIAVDAMRSGAFDFLVKPFDAKRLSITVRN
CCCCCHHHHHHHHHHCCCEEEEEEEECCEEEEEHHHHHCCCHHEEECCCCCCEEEEHHHH
ALKQRQLVNLVAKYESSLPKPHYMGFVGESLAMQTVYKTIDCVANSKASAFIIGESGTGK
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCH
EVCAHAIHNAGNRHDGPFVALNCASIPKDLIESEIFGHTKGAFTGAIANRDGAATRAHNG
HHHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCC
TLFLDEICEMDLELQSKLLRFIQTGVFQRVGGTKEEKVDVRFVSATNRMPWDEVKAGRFR
CEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHCCHHH
EDLFYRLHVIPIELPPLRMRGKDILLLASNLLKEYNKEEGKRFKGISCDAKQCLKSYQWP
HHHEEEEEEEEEECCCCCCCCCCCEEHHHHHHHHHCHHHCCEECCCCCCHHHHHHHCCCC
GNVRQLQNVIRQIVVLNDGELVELDMLPIQMTATSETTLAKVSEPVQQDQSVSIAASNSA
CCHHHHHHHHHHHEEECCCCEEEEEEEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCC
PVSFLEGIESAGFSADEHFPAVTPEAKSDDIVPLWLTEKQTIENAIALCKGNVPKAAALL
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHEE
DISASTIYRKRQTWEELENSLSH
ECHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301; 9748465 [H]