Click here to switch to the map view.

The map label for this gene is cat2 [H]

Identifier: 167622336

GI number: 167622336

Start: 463660

End: 464946

Strand: Direct

Name: cat2 [H]

Synonym: Shal_0396

Alternate gene names: 167622336

Gene position: 463660-464946 (Clockwise)

Preceding gene: 167622335

Following gene: 167622338

Centisome position: 8.87

GC content: 48.56

Gene sequence:

>1287_bases
ATGGCGCCAATTATCTGTGGCAGTGCTCTAGAGGCTGTATCTTTAATTGAGAGTGGTGAGACGTTATGGACTCACTCAAT
GGGAGCGACTCCGACCCTATTACTCAATGCCCTCGCTGAGCATGCTTTAACCAAAAAAGATCTCACTCTATTACAGTTAC
ATACCGAATGTGCTGAGTCGTTAAGTGATGAAAAGCTTAAGGGGCACCTACGACACCGGTGTTTCTTTGGTGGTTTGCCA
ACACGTTTGCTATTGCAGCAGGGTGATGCCGATTATGTGCCTATTTTTCTCTCTGAAGTACCTAAGCTATTTCGTTCGGG
TGAGCAGCCAATTGATACCGCAATTATTCAAGTCTCTCCTCCCGATAAGCATGGGATCTGTTCATTAGGCATTTCGGTTG
AAGCAACCTTAGCAGCCTGTCAAATGGCGGGAAAGATTATTGCTCATATCAACCCACAGATGCCGAGAACCCACGGCGAT
GGCTTTATCCATTACAGTAAATTTACTGCTGTTTATGAGCAGAGCATGCCACTGCCGCAGCACCCATTAGCCGCGAGCGA
TCAAACGAGTTTAGCTATCGGTAAAAATGTAGCCCAGTTAGTGCGTGATGGAGATTGTCTGCAGATGGGAATTGGGGCAA
TTCCTGATGCCGTACTCTCATGTTTAACTGAGCATAAAGATCTTGGCGTACATACCGAATTATTCTCCGATGGTGTGCTT
AACTTAGTCGAACTCGGGGTGATCACTAATCGCTTTAAAAAAGTGCATCCAGGCAAAACGGTCACCGGATTTGCCCTCGG
AAGCCAGCGGCTATATGACTTTGTTGACGATAACCCTTCGGTGATCTTTATGGATATTGAACAGGTTAATGACACCGCTA
TCATTCGTAAAAACCCCAATGTAATGGCCATTAACTCAGCGCTGCAGGTGGATATTTCAGGGCAAATCTGTGCAGATTCT
CTGGGCACGCGTATTTACTCTGGAGTGGGAGGGCAGATGGACTTTATTCGCGGAGCTGGGCTATCAGAAGGGGGTCGCTC
AGTGATAGCATTACCCAGCACTGCTGCTAGGGGCTCGGTATCGCGAATCGCCACCGTCTTGTCTCCAGGCGCTGGAGTGG
TGACCACACGCGCTCATGTGCACTATATAGTGACGGAGTTTGGTATTGCCAATCTGCGAGGCAAGTCCCTGCGTGAGCGC
GCGCGGGCACTGATCGATATCGCTCACCCAGACTTTAGAGAGCTGCTATGCCGAGAGACTTTTGATATGTGGGGCTTAAC
GGTGTAA

Upstream 100 bases:

>100_bases
TGGTATGAGATCAAATTTAAGTTAACTGAGTGTTTAAGCACTGTTAAAGCAAGACGTAACCTCATACACTGCGAACAGAT
TAATTATATTAGGTATCATT

Downstream 100 bases:

>100_bases
TCACTTAACTGTTTTGTTGCTGAGGTGAGTTAGGCATGCTGTTATCTGATACCGAACGCTTATCTCAATTCAGTGTTTAG
TTACAGCTTACACAAGGTAA

Product: acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MAPIICGSALEAVSLIESGETLWTHSMGATPTLLLNALAEHALTKKDLTLLQLHTECAESLSDEKLKGHLRHRCFFGGLP
TRLLLQQGDADYVPIFLSEVPKLFRSGEQPIDTAIIQVSPPDKHGICSLGISVEATLAACQMAGKIIAHINPQMPRTHGD
GFIHYSKFTAVYEQSMPLPQHPLAASDQTSLAIGKNVAQLVRDGDCLQMGIGAIPDAVLSCLTEHKDLGVHTELFSDGVL
NLVELGVITNRFKKVHPGKTVTGFALGSQRLYDFVDDNPSVIFMDIEQVNDTAIIRKNPNVMAINSALQVDISGQICADS
LGTRIYSGVGGQMDFIRGAGLSEGGRSVIALPSTAARGSVSRIATVLSPGAGVVTTRAHVHYIVTEFGIANLRGKSLRER
ARALIDIAHPDFRELLCRETFDMWGLTV

Sequences:

>Translated_428_residues
MAPIICGSALEAVSLIESGETLWTHSMGATPTLLLNALAEHALTKKDLTLLQLHTECAESLSDEKLKGHLRHRCFFGGLP
TRLLLQQGDADYVPIFLSEVPKLFRSGEQPIDTAIIQVSPPDKHGICSLGISVEATLAACQMAGKIIAHINPQMPRTHGD
GFIHYSKFTAVYEQSMPLPQHPLAASDQTSLAIGKNVAQLVRDGDCLQMGIGAIPDAVLSCLTEHKDLGVHTELFSDGVL
NLVELGVITNRFKKVHPGKTVTGFALGSQRLYDFVDDNPSVIFMDIEQVNDTAIIRKNPNVMAINSALQVDISGQICADS
LGTRIYSGVGGQMDFIRGAGLSEGGRSVIALPSTAARGSVSRIATVLSPGAGVVTTRAHVHYIVTEFGIANLRGKSLRER
ARALIDIAHPDFRELLCRETFDMWGLTV
>Mature_427_residues
APIICGSALEAVSLIESGETLWTHSMGATPTLLLNALAEHALTKKDLTLLQLHTECAESLSDEKLKGHLRHRCFFGGLPT
RLLLQQGDADYVPIFLSEVPKLFRSGEQPIDTAIIQVSPPDKHGICSLGISVEATLAACQMAGKIIAHINPQMPRTHGDG
FIHYSKFTAVYEQSMPLPQHPLAASDQTSLAIGKNVAQLVRDGDCLQMGIGAIPDAVLSCLTEHKDLGVHTELFSDGVLN
LVELGVITNRFKKVHPGKTVTGFALGSQRLYDFVDDNPSVIFMDIEQVNDTAIIRKNPNVMAINSALQVDISGQICADSL
GTRIYSGVGGQMDFIRGAGLSEGGRSVIALPSTAARGSVSRIATVLSPGAGVVTTRAHVHYIVTEFGIANLRGKSLRERA
RALIDIAHPDFRELLCRETFDMWGLTV

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=384, Percent_Identity=28.125, Blast_Score=92, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI32563853, Length=422, Percent_Identity=47.8672985781991, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17538151, Length=426, Percent_Identity=43.1924882629108, Blast_Score=344, Evalue=4e-95,
Organism=Saccharomyces cerevisiae, GI6319456, Length=472, Percent_Identity=24.364406779661, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21358615, Length=417, Percent_Identity=47.9616306954436, Blast_Score=387, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 46074; Mature: 45942

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPIICGSALEAVSLIESGETLWTHSMGATPTLLLNALAEHALTKKDLTLLQLHTECAES
CCCEECCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LSDEKLKGHLRHRCFFGGLPTRLLLQQGDADYVPIFLSEVPKLFRSGEQPIDTAIIQVSP
HCHHHHHHHHHHHHEECCCCHHHHHCCCCCCEEHHHHHHHHHHHHCCCCCCCEEEEEECC
PDKHGICSLGISVEATLAACQMAGKIIAHINPQMPRTHGDGFIHYSKFTAVYEQSMPLPQ
CCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCC
HPLAASDQTSLAIGKNVAQLVRDGDCLQMGIGAIPDAVLSCLTEHKDLGVHTELFSDGVL
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHCHHH
NLVELGVITNRFKKVHPGKTVTGFALGSQRLYDFVDDNPSVIFMDIEQVNDTAIIRKNPN
HHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCC
VMAINSALQVDISGQICADSLGTRIYSGVGGQMDFIRGAGLSEGGRSVIALPSTAARGSV
EEEECCEEEEECCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCHH
SRIATVLSPGAGVVTTRAHVHYIVTEFGIANLRGKSLRERARALIDIAHPDFRELLCRET
HHHHHHHCCCCCEEEEHHHEEEEEECCCCCCCCCHHHHHHHHHHEECCCCCHHHHHHHHH
FDMWGLTV
HHHCCCCC
>Mature Secondary Structure 
APIICGSALEAVSLIESGETLWTHSMGATPTLLLNALAEHALTKKDLTLLQLHTECAES
CCEECCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LSDEKLKGHLRHRCFFGGLPTRLLLQQGDADYVPIFLSEVPKLFRSGEQPIDTAIIQVSP
HCHHHHHHHHHHHHEECCCCHHHHHCCCCCCEEHHHHHHHHHHHHCCCCCCCEEEEEECC
PDKHGICSLGISVEATLAACQMAGKIIAHINPQMPRTHGDGFIHYSKFTAVYEQSMPLPQ
CCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCC
HPLAASDQTSLAIGKNVAQLVRDGDCLQMGIGAIPDAVLSCLTEHKDLGVHTELFSDGVL
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHCHHH
NLVELGVITNRFKKVHPGKTVTGFALGSQRLYDFVDDNPSVIFMDIEQVNDTAIIRKNPN
HHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCC
VMAINSALQVDISGQICADSLGTRIYSGVGGQMDFIRGAGLSEGGRSVIALPSTAARGSV
EEEECCEEEEECCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCHH
SRIATVLSPGAGVVTTRAHVHYIVTEFGIANLRGKSLRERARALIDIAHPDFRELLCRET
HHHHHHHCCCCCEEEEHHHEEEEEECCCCCCCCCHHHHHHHHHHEECCCCCHHHHHHHHH
FDMWGLTV
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]