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The map label for this gene is pdxY [H]

Identifier: 167622297

GI number: 167622297

Start: 422650

End: 423513

Strand: Direct

Name: pdxY [H]

Synonym: Shal_0356

Alternate gene names: 167622297

Gene position: 422650-423513 (Clockwise)

Preceding gene: 167622296

Following gene: 167622301

Centisome position: 8.09

GC content: 49.07

Gene sequence:

>864_bases
ATGAAGCGGATCTTATCCATTCAATCCCATGTGGTATTTGGCTGCGCAGGAAACAGTAGCGCCGTATTCCCAATGCGTCG
TCTCGGTATGGAGGTGTGGCCAATTAACACGGTGCAGTTCTCTAACCATACTCAGTATGCACAAGGATGGACGGGAACTG
TCATGCCTGCGGGTCAGATCACCGAGTTGGTACAAGGGTTAGACAATATCGGTAAACTGCAAACCTGTGATGCCATTCTC
AGTGGCTATCTTGGCAGTGCAGAGCAAGGTGGTGAAATTGTCGCAGCCGTGAAAAAGATGAAAGCCCTCAATCCTAATGC
GATTTACTTCTGCGATCCTGTGATGGGCCACCCAGAGAAGGGCTGCATCGTTGCGCCGGGCGTGCAAGAGTTCCTAAAAA
CTCAAGCTTTGGCTGAAGCCGATATTATCGCGCCTAACCTGTTAGAGCTGGAAACGCTCACAGATAGAGAGTTGCATAAT
CTGGACGAGGTGATAAATGCGTGTGAATGCTTGCTAGAAAAAGGGCTTGAGATGGTAGTCGTGAAGCACCTTGCTAAGGC
CGCCACTTGCCAAGAGCAGTTTGAGATGTTGCTGGTGACCAAGGCTGGCAGTTACTTAATCTCTCGTCCTTTATATGAAT
TTGAAAAGCAACCTGTGGGCGTCGGTGACTTAATCAGTGGCTTGATGTTGGCTAATCTGCAAGCTGGTTTTAGCCCAGTT
GAAGCATTTGAGCGCACTAATGCCTCAGTGGATGCTGTACTGCTAGAGACCTTTAACCAAGGCGCTTATGAGCTACAATT
AATTGGCGCGCAGGATGCCATTGCATCGCCGGTAATTAAGGCGCACGCCAAGCGAGTAAACTAA

Upstream 100 bases:

>100_bases
GAGACTAATTGGTATAATCCGTGAAAACCTCGAGTAGCTGTAAACAAGCAGCTGTAGAGCACCCTCTATTAAATCGCTAA
TAAAATTAAAGGTTGTAACC

Downstream 100 bases:

>100_bases
CTCAAGCTCATTAGTATAAGAGTTAAGAGGCGGAATTTAATGAGCCTACTCCATTCAGGGAGCAGGCTCTTTTCTTAGCC
ATTACCGTAAGCGCTGCGCT

Product: pyridoxal kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKRILSIQSHVVFGCAGNSSAVFPMRRLGMEVWPINTVQFSNHTQYAQGWTGTVMPAGQITELVQGLDNIGKLQTCDAIL
SGYLGSAEQGGEIVAAVKKMKALNPNAIYFCDPVMGHPEKGCIVAPGVQEFLKTQALAEADIIAPNLLELETLTDRELHN
LDEVINACECLLEKGLEMVVVKHLAKAATCQEQFEMLLVTKAGSYLISRPLYEFEKQPVGVGDLISGLMLANLQAGFSPV
EAFERTNASVDAVLLETFNQGAYELQLIGAQDAIASPVIKAHAKRVN

Sequences:

>Translated_287_residues
MKRILSIQSHVVFGCAGNSSAVFPMRRLGMEVWPINTVQFSNHTQYAQGWTGTVMPAGQITELVQGLDNIGKLQTCDAIL
SGYLGSAEQGGEIVAAVKKMKALNPNAIYFCDPVMGHPEKGCIVAPGVQEFLKTQALAEADIIAPNLLELETLTDRELHN
LDEVINACECLLEKGLEMVVVKHLAKAATCQEQFEMLLVTKAGSYLISRPLYEFEKQPVGVGDLISGLMLANLQAGFSPV
EAFERTNASVDAVLLETFNQGAYELQLIGAQDAIASPVIKAHAKRVN
>Mature_287_residues
MKRILSIQSHVVFGCAGNSSAVFPMRRLGMEVWPINTVQFSNHTQYAQGWTGTVMPAGQITELVQGLDNIGKLQTCDAIL
SGYLGSAEQGGEIVAAVKKMKALNPNAIYFCDPVMGHPEKGCIVAPGVQEFLKTQALAEADIIAPNLLELETLTDRELHN
LDEVINACECLLEKGLEMVVVKHLAKAATCQEQFEMLLVTKAGSYLISRPLYEFEKQPVGVGDLISGLMLANLQAGFSPV
EAFERTNASVDAVLLETFNQGAYELQLIGAQDAIASPVIKAHAKRVN

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=268, Percent_Identity=32.4626865671642, Blast_Score=133, Evalue=1e-31,
Organism=Escherichia coli, GI1787924, Length=278, Percent_Identity=57.9136690647482, Blast_Score=325, Evalue=2e-90,
Organism=Escherichia coli, GI1788758, Length=264, Percent_Identity=29.1666666666667, Blast_Score=106, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17507759, Length=288, Percent_Identity=31.25, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17507757, Length=298, Percent_Identity=30.5369127516779, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320806, Length=235, Percent_Identity=33.6170212765957, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324354, Length=180, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45553007, Length=311, Percent_Identity=31.8327974276527, Blast_Score=137, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31044; Mature: 31044

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILSIQSHVVFGCAGNSSAVFPMRRLGMEVWPINTVQFSNHTQYAQGWTGTVMPAGQI
CCCHHEECCEEEEEECCCCCCCCHHHHCCCEEECCCEEEECCCCCHHCCCCCCCCCCHHH
TELVQGLDNIGKLQTCDAILSGYLGSAEQGGEIVAAVKKMKALNPNAIYFCDPVMGHPEK
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCC
GCIVAPGVQEFLKTQALAEADIIAPNLLELETLTDRELHNLDEVINACECLLEKGLEMVV
CCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHH
VKHLAKAATCQEQFEMLLVTKAGSYLISRPLYEFEKQPVGVGDLISGLMLANLQAGFSPV
HHHHHHHHHHHHHHHEEEEECCCCHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCHH
EAFERTNASVDAVLLETFNQGAYELQLIGAQDAIASPVIKAHAKRVN
HHHHHCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRILSIQSHVVFGCAGNSSAVFPMRRLGMEVWPINTVQFSNHTQYAQGWTGTVMPAGQI
CCCHHEECCEEEEEECCCCCCCCHHHHCCCEEECCCEEEECCCCCHHCCCCCCCCCCHHH
TELVQGLDNIGKLQTCDAILSGYLGSAEQGGEIVAAVKKMKALNPNAIYFCDPVMGHPEK
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCC
GCIVAPGVQEFLKTQALAEADIIAPNLLELETLTDRELHNLDEVINACECLLEKGLEMVV
CCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHH
VKHLAKAATCQEQFEMLLVTKAGSYLISRPLYEFEKQPVGVGDLISGLMLANLQAGFSPV
HHHHHHHHHHHHHHHEEEEECCCCHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCHH
EAFERTNASVDAVLLETFNQGAYELQLIGAQDAIASPVIKAHAKRVN
HHHHHCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA