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The map label for this gene is fieF [H]

Identifier: 167622281

GI number: 167622281

Start: 404164

End: 405033

Strand: Direct

Name: fieF [H]

Synonym: Shal_0340

Alternate gene names: 167622281

Gene position: 404164-405033 (Clockwise)

Preceding gene: 167622280

Following gene: 167622285

Centisome position: 7.73

GC content: 50.0

Gene sequence:

>870_bases
ATGACTGACACTTCCCAATATGACTTCTGGGTTAAGCTGGCCAGCCGCGCAGCCGTTGCGACAGCTTTAACCCTTATCAC
TATCAAGTTTGCGGCGTGGATGTATTCCGGCTCTGCCAGTATGCTCGCCTCGTTAACGGACTCCTTTGCCGATACTCTCG
CGTCTATTGTGAATTTTATCGCGATTCGTTACGCCATCGTGCCAGCCGATCAGGATCATCGCTACGGTCACGGTAAGGCG
GAGCCGCTAGCGGCATTGGCGCAATCGGCCTTTATTCTTGGTTCCGCTTTCTTGTTATTGCTTCATGGTGGTGAGCGTCT
GATCAATCCGGTTGAGGTGCAGCATGCTACCTTAGGTGTGGTGGTATCCATTATTGCTATCGTGTTGACACTTGCATTGG
TTATGCTGCAAAAGCGTGCATTAGCGGCAACATCGAGTACCGTGATAGAAGCCGATGCGCTGCACTATAAATCGGATCTA
TTTCTCAATGCCGCAGTACTGCTGGCACTAGTTTTGGCGCAGTACGGCTGGTTGTGGGCCGATGGTTTATTTGCGCTGTT
AATTGCATTATTCATTGGTCAACAGGCGGTTGGCTTAGCTTATCGCTCAGTGCAGTCTTTACTCGACCGAGAGTTAGATG
ATGAGACGCGCGGTAAAATCACTGAAATTGCTAAGCGTGATCCGCAGGTGAAAGGGATCCACGACTTACGTACACGCGAG
TCGGGTAAGACCATGTTTATCCAGTTTCATCTTGAGTTAGACGGTGATTTGAGTCTGCTGCAAGCACATAAAATTGCCGT
GGAGACATCCGAGAGGGTGCGACAGGAGTTTGTCGACTCTGAGGTGATTATTCACCAAGATCCGGTGTAG

Upstream 100 bases:

>100_bases
GTCAATTGGTTTTAACTTGAAGGAAATCATCAGTTTTTCTCTCTCGTTTGTTATAAACTTAAGATCTGTGTTTCCCTTAC
TGTACAAGTAAACAGATTTT

Downstream 100 bases:

>100_bases
TGACTGGCTTATAATCAAAAAAGGAGATCCTGTTGATCTCCTTTTTTGTTTTCAGCCCTAAAGCATCTACTTCAGAAGGT
GGATTCTTTACTGCAAGCCG

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTDTSQYDFWVKLASRAAVATALTLITIKFAAWMYSGSASMLASLTDSFADTLASIVNFIAIRYAIVPADQDHRYGHGKA
EPLAALAQSAFILGSAFLLLLHGGERLINPVEVQHATLGVVVSIIAIVLTLALVMLQKRALAATSSTVIEADALHYKSDL
FLNAAVLLALVLAQYGWLWADGLFALLIALFIGQQAVGLAYRSVQSLLDRELDDETRGKITEIAKRDPQVKGIHDLRTRE
SGKTMFIQFHLELDGDLSLLQAHKIAVETSERVRQEFVDSEVIIHQDPV

Sequences:

>Translated_289_residues
MTDTSQYDFWVKLASRAAVATALTLITIKFAAWMYSGSASMLASLTDSFADTLASIVNFIAIRYAIVPADQDHRYGHGKA
EPLAALAQSAFILGSAFLLLLHGGERLINPVEVQHATLGVVVSIIAIVLTLALVMLQKRALAATSSTVIEADALHYKSDL
FLNAAVLLALVLAQYGWLWADGLFALLIALFIGQQAVGLAYRSVQSLLDRELDDETRGKITEIAKRDPQVKGIHDLRTRE
SGKTMFIQFHLELDGDLSLLQAHKIAVETSERVRQEFVDSEVIIHQDPV
>Mature_288_residues
TDTSQYDFWVKLASRAAVATALTLITIKFAAWMYSGSASMLASLTDSFADTLASIVNFIAIRYAIVPADQDHRYGHGKAE
PLAALAQSAFILGSAFLLLLHGGERLINPVEVQHATLGVVVSIIAIVLTLALVMLQKRALAATSSTVIEADALHYKSDLF
LNAAVLLALVLAQYGWLWADGLFALLIALFIGQQAVGLAYRSVQSLLDRELDDETRGKITEIAKRDPQVKGIHDLRTRES
GKTMFIQFHLELDGDLSLLQAHKIAVETSERVRQEFVDSEVIIHQDPV

Specific function: Cation-efflux transporter that may have a role in detoxification [H]

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily [H]

Homologues:

Organism=Homo sapiens, GI57164948, Length=248, Percent_Identity=27.4193548387097, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790349, Length=265, Percent_Identity=49.811320754717, Blast_Score=262, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI115533508, Length=250, Percent_Identity=25.2, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115533506, Length=250, Percent_Identity=25.2, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 31614; Mature: 31483

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTSQYDFWVKLASRAAVATALTLITIKFAAWMYSGSASMLASLTDSFADTLASIVNFI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AIRYAIVPADQDHRYGHGKAEPLAALAQSAFILGSAFLLLLHGGERLINPVEVQHATLGV
HHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHH
VVSIIAIVLTLALVMLQKRALAATSSTVIEADALHYKSDLFLNAAVLLALVLAQYGWLWA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
DGLFALLIALFIGQQAVGLAYRSVQSLLDRELDDETRGKITEIAKRDPQVKGIHDLRTRE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHCC
SGKTMFIQFHLELDGDLSLLQAHKIAVETSERVRQEFVDSEVIIHQDPV
CCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
>Mature Secondary Structure 
TDTSQYDFWVKLASRAAVATALTLITIKFAAWMYSGSASMLASLTDSFADTLASIVNFI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AIRYAIVPADQDHRYGHGKAEPLAALAQSAFILGSAFLLLLHGGERLINPVEVQHATLGV
HHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHH
VVSIIAIVLTLALVMLQKRALAATSSTVIEADALHYKSDLFLNAAVLLALVLAQYGWLWA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
DGLFALLIALFIGQQAVGLAYRSVQSLLDRELDDETRGKITEIAKRDPQVKGIHDLRTRE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHCC
SGKTMFIQFHLELDGDLSLLQAHKIAVETSERVRQEFVDSEVIIHQDPV
CCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA