Click here to switch to the map view.

The map label for this gene is ctaD [H]

Identifier: 167622198

GI number: 167622198

Start: 306512

End: 308116

Strand: Reverse

Name: ctaD [H]

Synonym: Shal_0257

Alternate gene names: 167622198

Gene position: 308116-306512 (Counterclockwise)

Preceding gene: 167622199

Following gene: 167622197

Centisome position: 5.89

GC content: 48.91

Gene sequence:

>1605_bases
ATGAGCACAATTACACAAGACTCGCCAGCCGCTCACGACGATCACCATGATGACCATCATCATGGGGCGCCAAAAGGCAT
TATGCGCTGGTTGTTAACGACTAATCATAAAGATATCGGCACCCTCTACCTTTTGTTCAGTTTAATCATGTTTTTTGTGG
GTGGCGCGATGGCCATGGTGATCCGTGCTGAACTGTTCCAGCCTGGATTACAGCTTGTCGAACCTAACTTCTTTAATCAG
ATGACCACGGTTCACGGTTTGGTCATGGTGTTTGGTGCGGTGATGCCCGCCTTCACAGGCCTAGCTAACTGGTTGATCCC
CATGATGATAGGTGCGCCAGATATGGCTCTGCCTCGCATGAATAACTGGAGCTTCTGGATCTTACCGTTCGCATTTACCA
TTTTGCTCAGCTCACTCTTTATGGAAGGGGGCGGCCCCAACTTCGGTTGGACATTCTACGCACCGCTCTCAACCACTTAT
AGCCCAGATAGCACCGCTCTATTCGTGTTTGCCGTTCACATTATGGGAATAAGTTCGATCATGGGGGCAATTAATGTCAT
CGTCACCATCGTCAATTTACGAGCACCGGGTATGACCTGGATGAAACTGCCGCTATTTGTATGGACCTGGTTAATCACCG
CATTCCTGCTGATCGCGGTTATGCCGGTTCTCGCTGGTACCGTGACCATGGTACTGACCGATAAATACTTTGGCACCAGC
TTTTTCGATGCTGCAGGCGGCGGCGATCCTGTGATGTTTCAGCATATTTTCTGGTTCTTTGGCCACCCTGAAGTTTACAT
CATGATCTTACCGTCATTCGGTATCATCTCTGCCATCGTGCCCGCCTTTAGCCGTAAGCGACTATTTGGTTATTCATCGA
TGGTTTATGCCACAGCGAGTATCGCTATCTTGTCGTTCTTAGTTTGGGCACACCACATGTTTACTACCGGTATGCCGGTA
TTTGCCGAGCTGTTTTTCATGTATTGCACCATGCTAATTGCGGTGCCGACCGGTGTGAAAGTATTTAACTGGGTGGCGAC
CATGTGGCGAGGTTCTATCACTTTTGAAACCCCCATGCTTTTTGCGGTCGCCTTTATCATCTTATTCACCATAGGCGGTT
TTTCAGGCCTTATGCTAGCCATTGCACCAGCGGATTTCCAGTATCACGATACCTACTTTGTGGTGGCCCATTTCCACTAC
GTACTGGTGACTGGAGCGATATTTTCCATAATGGCAGCCGCCTATTATTGGCTACCCAAATGGACTGGCCATATGTATAG
CGAAACCTTAGGCCGTTGGCACTTCTGGTGTTCGGTAATTTCGGTCAACATTCTGTTTTTCCCGATGCACTTCTTAGGCT
TAGCTGGCATGCCAAGACGCATTCCTGATTATGCTATCCAGTTTGCCGATGTAAACCAAATCGTATCGATTGGCGGTTTC
GCCTTTGGTCTTTCACAGCTGATCTTTTTAGCCGTAGTGATTAAATGTATTCGCGGTGGTGAGAAAGCCCCAGCCAAGCC
ATGGGAAGGTGCCGAAGGACTAGAGTGGACGCTTCCAAGCCCAGCGCCTTACCACTCGTTTACCACCCCTCCAGAGGTGA
AATAA

Upstream 100 bases:

>100_bases
TGCTGCTGTGGTGACTTATGAGCGCAATGCCTGGGGTAATGACTCTGGTGATGCGGTTCAAGCTTCTGATGTTGATGGTC
ACGCAAAGTAAGGGATTAAC

Downstream 100 bases:

>100_bases
AGATGGCAGAGATTAAGCGCTACTCCAATCGCAAACTGATCGCCGCGCTAATTATTGGCGCTGTGGGCATGTTTGGCTTT
GGCTTTGCCCTTGTTCCTTT

Product: cytochrome c oxidase subunit I type

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MSTITQDSPAAHDDHHDDHHHGAPKGIMRWLLTTNHKDIGTLYLLFSLIMFFVGGAMAMVIRAELFQPGLQLVEPNFFNQ
MTTVHGLVMVFGAVMPAFTGLANWLIPMMIGAPDMALPRMNNWSFWILPFAFTILLSSLFMEGGGPNFGWTFYAPLSTTY
SPDSTALFVFAVHIMGISSIMGAINVIVTIVNLRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGTVTMVLTDKYFGTS
FFDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKRLFGYSSMVYATASIAILSFLVWAHHMFTTGMPV
FAELFFMYCTMLIAVPTGVKVFNWVATMWRGSITFETPMLFAVAFIILFTIGGFSGLMLAIAPADFQYHDTYFVVAHFHY
VLVTGAIFSIMAAAYYWLPKWTGHMYSETLGRWHFWCSVISVNILFFPMHFLGLAGMPRRIPDYAIQFADVNQIVSIGGF
AFGLSQLIFLAVVIKCIRGGEKAPAKPWEGAEGLEWTLPSPAPYHSFTTPPEVK

Sequences:

>Translated_534_residues
MSTITQDSPAAHDDHHDDHHHGAPKGIMRWLLTTNHKDIGTLYLLFSLIMFFVGGAMAMVIRAELFQPGLQLVEPNFFNQ
MTTVHGLVMVFGAVMPAFTGLANWLIPMMIGAPDMALPRMNNWSFWILPFAFTILLSSLFMEGGGPNFGWTFYAPLSTTY
SPDSTALFVFAVHIMGISSIMGAINVIVTIVNLRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGTVTMVLTDKYFGTS
FFDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKRLFGYSSMVYATASIAILSFLVWAHHMFTTGMPV
FAELFFMYCTMLIAVPTGVKVFNWVATMWRGSITFETPMLFAVAFIILFTIGGFSGLMLAIAPADFQYHDTYFVVAHFHY
VLVTGAIFSIMAAAYYWLPKWTGHMYSETLGRWHFWCSVISVNILFFPMHFLGLAGMPRRIPDYAIQFADVNQIVSIGGF
AFGLSQLIFLAVVIKCIRGGEKAPAKPWEGAEGLEWTLPSPAPYHSFTTPPEVK
>Mature_533_residues
STITQDSPAAHDDHHDDHHHGAPKGIMRWLLTTNHKDIGTLYLLFSLIMFFVGGAMAMVIRAELFQPGLQLVEPNFFNQM
TTVHGLVMVFGAVMPAFTGLANWLIPMMIGAPDMALPRMNNWSFWILPFAFTILLSSLFMEGGGPNFGWTFYAPLSTTYS
PDSTALFVFAVHIMGISSIMGAINVIVTIVNLRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGTVTMVLTDKYFGTSF
FDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKRLFGYSSMVYATASIAILSFLVWAHHMFTTGMPVF
AELFFMYCTMLIAVPTGVKVFNWVATMWRGSITFETPMLFAVAFIILFTIGGFSGLMLAIAPADFQYHDTYFVVAHFHYV
LVTGAIFSIMAAAYYWLPKWTGHMYSETLGRWHFWCSVISVNILFFPMHFLGLAGMPRRIPDYAIQFADVNQIVSIGGFA
FGLSQLIFLAVVIKCIRGGEKAPAKPWEGAEGLEWTLPSPAPYHSFTTPPEVK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=510, Percent_Identity=49.6078431372549, Blast_Score=450, Evalue=1e-126,
Organism=Escherichia coli, GI1786634, Length=514, Percent_Identity=39.4941634241245, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6226519, Length=530, Percent_Identity=47.9245283018868, Blast_Score=474, Evalue=1e-134,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=50, Blast_Score=314, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6226523, Length=248, Percent_Identity=46.3709677419355, Blast_Score=206, Evalue=7e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59568; Mature: 59437

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTITQDSPAAHDDHHDDHHHGAPKGIMRWLLTTNHKDIGTLYLLFSLIMFFVGGAMAMV
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
IRAELFQPGLQLVEPNFFNQMTTVHGLVMVFGAVMPAFTGLANWLIPMMIGAPDMALPRM
HHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NNWSFWILPFAFTILLSSLFMEGGGPNFGWTFYAPLSTTYSPDSTALFVFAVHIMGISSI
CCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
MGAINVIVTIVNLRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGTVTMVLTDKYFGTS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHCCCC
FFDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKRLFGYSSMVYATAS
HHCCCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHHHH
IAILSFLVWAHHMFTTGMPVFAELFFMYCTMLIAVPTGVKVFNWVATMWRGSITFETPML
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEECHHHH
FAVAFIILFTIGGFSGLMLAIAPADFQYHDTYFVVAHFHYVLVTGAIFSIMAAAYYWLPK
HHHHHHHHHHHCCHHHHEEEEECCCCEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHC
WTGHMYSETLGRWHFWCSVISVNILFFPMHFLGLAGMPRRIPDYAIQFADVNQIVSIGGF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEHHHHHHHHHHHHH
AFGLSQLIFLAVVIKCIRGGEKAPAKPWEGAEGLEWTLPSPAPYHSFTTPPEVK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STITQDSPAAHDDHHDDHHHGAPKGIMRWLLTTNHKDIGTLYLLFSLIMFFVGGAMAMV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
IRAELFQPGLQLVEPNFFNQMTTVHGLVMVFGAVMPAFTGLANWLIPMMIGAPDMALPRM
HHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NNWSFWILPFAFTILLSSLFMEGGGPNFGWTFYAPLSTTYSPDSTALFVFAVHIMGISSI
CCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
MGAINVIVTIVNLRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGTVTMVLTDKYFGTS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHCCCC
FFDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKRLFGYSSMVYATAS
HHCCCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHHHH
IAILSFLVWAHHMFTTGMPVFAELFFMYCTMLIAVPTGVKVFNWVATMWRGSITFETPML
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEECHHHH
FAVAFIILFTIGGFSGLMLAIAPADFQYHDTYFVVAHFHYVLVTGAIFSIMAAAYYWLPK
HHHHHHHHHHHCCHHHHEEEEECCCCEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHC
WTGHMYSETLGRWHFWCSVISVNILFFPMHFLGLAGMPRRIPDYAIQFADVNQIVSIGGF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEHHHHHHHHHHHHH
AFGLSQLIFLAVVIKCIRGGEKAPAKPWEGAEGLEWTLPSPAPYHSFTTPPEVK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]