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The map label for this gene is ctaC [H]

Identifier: 167622199

GI number: 167622199

Start: 308126

End: 309712

Strand: Reverse

Name: ctaC [H]

Synonym: Shal_0258

Alternate gene names: 167622199

Gene position: 309712-308126 (Counterclockwise)

Preceding gene: 167622200

Following gene: 167622198

Centisome position: 5.93

GC content: 47.7

Gene sequence:

>1587_bases
GTGAAGCAATTGTTGTATTGTGTGCTGGCGTTACTATTTTCGCCCGTACTTTTTGCATCAGAAATGCCACTGAATATGAC
AGAGGGTGTTACGGAGATCAGTGGGCGAATTTACAGCCTTCACATGGTTATTCTGTACATCTGCTGCGCTATTGGCATCG
TGGTTTTTGGCATCATGATTTACGCCATGATCAACCACCGCAAATCAAAAGGCGCTGTCGCCGCCAACTTTCATGAAAGT
ACTAAAGTCGAGATCCTTTGGACTGTAGTACCTTTTATTATTCTTATAGTCATGGCTATTCCTGCAACCAAAACCTTGAT
TGCAATGGAAGATCCGAGCAACGCCGATCTCACCATCAAGATTACTGGCTCACAGTGGAAATGGCATTACAGCTATTTCG
ATCAAGATATTGAGTTCTTCAGCCTATTATCGACACCTAGGGAACAGATAATAGGCGATGAAACCAAAGGCGAAAACTAC
CTGCTAGAGGTTGATAAACCACTGGTTCTACCTATCAACCGCAAAGTGCGCTTCTTAATGACCTCCGAAGACGTTATCCA
CTCTTGGTGGGTACCCGCTTTTGCAGTCAAAAAGGATGCCAATCCGGGATTTATTAATGAGGCATGGACCCGCATCGACA
AGCCCGGCACCTATCGAGGTCAATGCGCCGAGCTCTGCGGTAAAGACCACGGCTTTATGCCGATTGTGGTCGAAGCAGTA
TCGGAAGAGGATTTCGATGCCTGGCTAATCACGCAGCAACAACAAGCGCAAAATGCTGAAGCGGCTGCCAAGGCGGCATT
ATCGCAAACCTTAACCATGGATGAGTTAATGACTAAAGGTGAGCAAATCTATCTTGCTCGTTGTGCAGCCTGCCACCAGC
CTAATGGTGCAGGTCTACCCGGTGTATTTCCTTCTCTTATTGGCAGCCCAATTATCAAAGGGCCTGCTCAGCTTCATATC
GATATCGTGTTAAATGGTAAACCGGGCACTGCCATGCAAGCATTTTTAAACCAGCTAACGGCGACTGAAATTGCAGCCGT
AGTGACCTATGAGCGCAATGCTTGGGGCAATAACTCAGGTGATACCGTTCAAGCCTCTGATGTGAGCTCAGATACGACCA
CACCAGCGACATCCGTAGATTCAAGCCCTGCCACCCCAACCACTTTACCCGCAACCTTACCTGCAACACGACCTGAGGTT
AAACAAGCTATAGCCTCAGAAACCCAAGCCGATGACCAGGTAGCTAAAGAGCTTGCAACGGCTCCATTAGGTGATTTAGC
CATGAATGAACTCATTACCATGGGTGAAAAAGTCTATATGGCTAACTGTGCAGCTTGTCATCAAGCTGCTGGCACAGGTC
TACCTCCTGCATTCCCATCATTAGTGGGCAGTCCTATCGTCAAAGGCCCTATAGCTGCTCACCTTGATATTGTTATCAAT
GGCAAACCGGGCACGGCAATGCAGTCATTTAGTGCAGTGCTGACACCACAACAGCTTGCTGCTGTGGTGACTTATGAGCG
CAATGCCTGGGGTAATGACTCTGGTGATGCGGTTCAAGCTTCTGATGTTGATGGTCACGCAAAGTAA

Upstream 100 bases:

>100_bases
CTTTGAAGTCATCGTTGCTTTTTTGGGAACTGAAGAGTTTACATAGAGCAGAGACTTACTGTGTGACTCTTCTTTGTCTT
GTCGACAGAGGAGAAGTCTA

Downstream 100 bases:

>100_bases
GGGATTAACATGAGCACAATTACACAAGACTCGCCAGCCGCTCACGACGATCACCATGATGACCATCATCATGGGGCGCC
AAAAGGCATTATGCGCTGGT

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MKQLLYCVLALLFSPVLFASEMPLNMTEGVTEISGRIYSLHMVILYICCAIGIVVFGIMIYAMINHRKSKGAVAANFHES
TKVEILWTVVPFIILIVMAIPATKTLIAMEDPSNADLTIKITGSQWKWHYSYFDQDIEFFSLLSTPREQIIGDETKGENY
LLEVDKPLVLPINRKVRFLMTSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGTYRGQCAELCGKDHGFMPIVVEAV
SEEDFDAWLITQQQQAQNAEAAAKAALSQTLTMDELMTKGEQIYLARCAACHQPNGAGLPGVFPSLIGSPIIKGPAQLHI
DIVLNGKPGTAMQAFLNQLTATEIAAVVTYERNAWGNNSGDTVQASDVSSDTTTPATSVDSSPATPTTLPATLPATRPEV
KQAIASETQADDQVAKELATAPLGDLAMNELITMGEKVYMANCAACHQAAGTGLPPAFPSLVGSPIVKGPIAAHLDIVIN
GKPGTAMQSFSAVLTPQQLAAVVTYERNAWGNDSGDAVQASDVDGHAK

Sequences:

>Translated_528_residues
MKQLLYCVLALLFSPVLFASEMPLNMTEGVTEISGRIYSLHMVILYICCAIGIVVFGIMIYAMINHRKSKGAVAANFHES
TKVEILWTVVPFIILIVMAIPATKTLIAMEDPSNADLTIKITGSQWKWHYSYFDQDIEFFSLLSTPREQIIGDETKGENY
LLEVDKPLVLPINRKVRFLMTSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGTYRGQCAELCGKDHGFMPIVVEAV
SEEDFDAWLITQQQQAQNAEAAAKAALSQTLTMDELMTKGEQIYLARCAACHQPNGAGLPGVFPSLIGSPIIKGPAQLHI
DIVLNGKPGTAMQAFLNQLTATEIAAVVTYERNAWGNNSGDTVQASDVSSDTTTPATSVDSSPATPTTLPATLPATRPEV
KQAIASETQADDQVAKELATAPLGDLAMNELITMGEKVYMANCAACHQAAGTGLPPAFPSLVGSPIVKGPIAAHLDIVIN
GKPGTAMQSFSAVLTPQQLAAVVTYERNAWGNDSGDAVQASDVDGHAK
>Mature_528_residues
MKQLLYCVLALLFSPVLFASEMPLNMTEGVTEISGRIYSLHMVILYICCAIGIVVFGIMIYAMINHRKSKGAVAANFHES
TKVEILWTVVPFIILIVMAIPATKTLIAMEDPSNADLTIKITGSQWKWHYSYFDQDIEFFSLLSTPREQIIGDETKGENY
LLEVDKPLVLPINRKVRFLMTSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGTYRGQCAELCGKDHGFMPIVVEAV
SEEDFDAWLITQQQQAQNAEAAAKAALSQTLTMDELMTKGEQIYLARCAACHQPNGAGLPGVFPSLIGSPIIKGPAQLHI
DIVLNGKPGTAMQAFLNQLTATEIAAVVTYERNAWGNNSGDTVQASDVSSDTTTPATSVDSSPATPTTLPATLPATRPEV
KQAIASETQADDQVAKELATAPLGDLAMNELITMGEKVYMANCAACHQAAGTGLPPAFPSLVGSPIVKGPIAAHLDIVIN
GKPGTAMQSFSAVLTPQQLAAVVTYERNAWGNDSGDAVQASDVDGHAK

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=168, Percent_Identity=38.6904761904762, Blast_Score=136, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6226540, Length=234, Percent_Identity=32.4786324786325, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 56893; Mature: 56893

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLLYCVLALLFSPVLFASEMPLNMTEGVTEISGRIYSLHMVILYICCAIGIVVFGIMI
CHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAMINHRKSKGAVAANFHESTKVEILWTVVPFIILIVMAIPATKTLIAMEDPSNADLTIK
HHHHHCCCCCCCEEECCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEE
ITGSQWKWHYSYFDQDIEFFSLLSTPREQIIGDETKGENYLLEVDKPLVLPINRKVRFLM
EECCCEEEEHHHHHCHHHHHHHHCCCHHHHCCCCCCCCCEEEEECCCEEEECCCCEEEEE
TSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGTYRGQCAELCGKDHGFMPIVVEAV
ECHHHHHHHCCCCEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEEEEEC
SEEDFDAWLITQQQQAQNAEAAAKAALSQTLTMDELMTKGEQIYLARCAACHQPNGAGLP
CCCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCC
GVFPSLIGSPIIKGPAQLHIDIVLNGKPGTAMQAFLNQLTATEIAAVVTYERNAWGNNSG
CCCHHHHCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCC
DTVQASDVSSDTTTPATSVDSSPATPTTLPATLPATRPEVKQAIASETQADDQVAKELAT
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
APLGDLAMNELITMGEKVYMANCAACHQAAGTGLPPAFPSLVGSPIVKGPIAAHLDIVIN
CCCHHHHHHHHHHHCCHHEEHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCEEEEEEEEE
GKPGTAMQSFSAVLTPQQLAAVVTYERNAWGNDSGDAVQASDVDGHAK
CCCCHHHHHHHHHCCHHHHHEEEEEECCCCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MKQLLYCVLALLFSPVLFASEMPLNMTEGVTEISGRIYSLHMVILYICCAIGIVVFGIMI
CHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAMINHRKSKGAVAANFHESTKVEILWTVVPFIILIVMAIPATKTLIAMEDPSNADLTIK
HHHHHCCCCCCCEEECCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEE
ITGSQWKWHYSYFDQDIEFFSLLSTPREQIIGDETKGENYLLEVDKPLVLPINRKVRFLM
EECCCEEEEHHHHHCHHHHHHHHCCCHHHHCCCCCCCCCEEEEECCCEEEECCCCEEEEE
TSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGTYRGQCAELCGKDHGFMPIVVEAV
ECHHHHHHHCCCCEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEEEEEC
SEEDFDAWLITQQQQAQNAEAAAKAALSQTLTMDELMTKGEQIYLARCAACHQPNGAGLP
CCCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCCC
GVFPSLIGSPIIKGPAQLHIDIVLNGKPGTAMQAFLNQLTATEIAAVVTYERNAWGNNSG
CCCHHHHCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCC
DTVQASDVSSDTTTPATSVDSSPATPTTLPATLPATRPEVKQAIASETQADDQVAKELAT
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
APLGDLAMNELITMGEKVYMANCAACHQAAGTGLPPAFPSLVGSPIVKGPIAAHLDIVIN
CCCHHHHHHHHHHHCCHHEEHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCEEEEEEEEE
GKPGTAMQSFSAVLTPQQLAAVVTYERNAWGNDSGDAVQASDVDGHAK
CCCCHHHHHHHHHCCHHHHHEEEEEECCCCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA