Click here to switch to the map view.

The map label for this gene is fixC [H]

Identifier: 167622158

GI number: 167622158

Start: 261446

End: 262735

Strand: Reverse

Name: fixC [H]

Synonym: Shal_0217

Alternate gene names: 167622158

Gene position: 262735-261446 (Counterclockwise)

Preceding gene: 167622159

Following gene: 167622157

Centisome position: 5.03

GC content: 45.43

Gene sequence:

>1290_bases
ATGTCAGAAGAATCATTTGACGCTATTATTGTAGGAGCTGGGCTAGCGGGATGTGTTGCTGCCTATGTTCTTGCCAAAGA
GGGAGCGGACGTTCTCGTAATCGAGCGCGGAAACTTTGCCGGCAGCAAAAATATGACTGGTGGTCGCCTGTACGCCCATA
GTCTAGAAAAAATCATTCCTGGTTTTGCTAAAGAAGCGCCAATAGAAAGAAAAGTCACTAAAGAGAAAGTGACCTTTCTG
ACCGATGATACTGGCGTCACTCTCGACTACCATAACGGCCGAGAGCAAAACTCAACTCAAGAATCTTACACCCTGTTAAG
AGGCGATTTTGATCAGTGGTTAATGGGCAAGGCCGAAGAGGTTGGTGCACAATTCATTACTGGTATTCGTGTTGAAGAGA
TCTTAACTCAAGATGGTAAGGTCATTGGCGTAAAGGCCGATGGCGACGAACTTACCGCCAAGTCGGTTATTTTAGCCGAA
GGCGTTAACCCAATACTGGGTGAACAGCTAGGTATGGTTAAGAGAGTCAAAGGCGATGTGATGGCAGTTGGGGCTAAAGA
GCTTATCGAACTACCTCAAGAAGTGATCCAAGATCGCTTCAACGTCAGCAAGGATGAAGGTTGCGCTTGGTTATTTGCCG
GTTCACCAGCCAATGGCCTAATGGGTGGCGGCTTTATCTATACCAACAAGAACTCTGTTTCATTGGGTATCGTTTGTGGA
TTGCATGACATAGGTAGCTCTAGTAAAACTGTGCCGCAAATGCTCGAAGACTTTAAAAATCACGCAATGATTAAGCCACT
GATTGAGGGTGGAAAGCTACTCGAGTATTCAGGTCATGTGGTCCCAGAAGCGGGTATTAACATGGTGCCTAAGCTAGTCG
ATGACGGCGTACTGATCGCAGGCGATGCTGCTGGGTTCTGTTTAAACTTAGGCTATACCGTACGTGGTATGGACTTGGCT
ATCGCTTCTGGCGAGGCCGCGGCAAAAGCAGTATTAGCCGCACGAGAAAAGAATGACTTTAGTGCCGAAGGTCTCTCTTC
TTACCAAACATTATTAGAAGACAGCTTCATTATGAAAGATCTTAAGCTATATAAAGATCTACCAGCCTTTATGGAAACAC
CACGCATCTTTAACCAGTACCCAAAGATGGTGGCCGACATAATGCAAAGCATGTTCACCGTTGATGGCACTCCATCACAA
CCAATAAGAAAAACCCTCATGAAGCACTGTAAAGAAGTGGGCTATATGAATCTGATCAAAGATGGAATTAAAGGAGTGAC
TTCAATATGA

Upstream 100 bases:

>100_bases
AAAGCCTAATCAAAGCACAATTTTTATTGTTCTTTCAATCGCCTCTTATCCTAGTAGAGACAAGAGGCGAATAGCCAAAT
TTATGTAGAGAGTGACGAGT

Downstream 100 bases:

>100_bases
GTGAAATAGTTAACGTCGATGTCAAATTAGGCGTCAATAAGTTTCATGTCGATGAGGGCCATCCTCATGTTATCTTAAAA
GACAATCCAGATATGAACGA

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSEESFDAIIVGAGLAGCVAAYVLAKEGADVLVIERGNFAGSKNMTGGRLYAHSLEKIIPGFAKEAPIERKVTKEKVTFL
TDDTGVTLDYHNGREQNSTQESYTLLRGDFDQWLMGKAEEVGAQFITGIRVEEILTQDGKVIGVKADGDELTAKSVILAE
GVNPILGEQLGMVKRVKGDVMAVGAKELIELPQEVIQDRFNVSKDEGCAWLFAGSPANGLMGGGFIYTNKNSVSLGIVCG
LHDIGSSSKTVPQMLEDFKNHAMIKPLIEGGKLLEYSGHVVPEAGINMVPKLVDDGVLIAGDAAGFCLNLGYTVRGMDLA
IASGEAAAKAVLAAREKNDFSAEGLSSYQTLLEDSFIMKDLKLYKDLPAFMETPRIFNQYPKMVADIMQSMFTVDGTPSQ
PIRKTLMKHCKEVGYMNLIKDGIKGVTSI

Sequences:

>Translated_429_residues
MSEESFDAIIVGAGLAGCVAAYVLAKEGADVLVIERGNFAGSKNMTGGRLYAHSLEKIIPGFAKEAPIERKVTKEKVTFL
TDDTGVTLDYHNGREQNSTQESYTLLRGDFDQWLMGKAEEVGAQFITGIRVEEILTQDGKVIGVKADGDELTAKSVILAE
GVNPILGEQLGMVKRVKGDVMAVGAKELIELPQEVIQDRFNVSKDEGCAWLFAGSPANGLMGGGFIYTNKNSVSLGIVCG
LHDIGSSSKTVPQMLEDFKNHAMIKPLIEGGKLLEYSGHVVPEAGINMVPKLVDDGVLIAGDAAGFCLNLGYTVRGMDLA
IASGEAAAKAVLAAREKNDFSAEGLSSYQTLLEDSFIMKDLKLYKDLPAFMETPRIFNQYPKMVADIMQSMFTVDGTPSQ
PIRKTLMKHCKEVGYMNLIKDGIKGVTSI
>Mature_428_residues
SEESFDAIIVGAGLAGCVAAYVLAKEGADVLVIERGNFAGSKNMTGGRLYAHSLEKIIPGFAKEAPIERKVTKEKVTFLT
DDTGVTLDYHNGREQNSTQESYTLLRGDFDQWLMGKAEEVGAQFITGIRVEEILTQDGKVIGVKADGDELTAKSVILAEG
VNPILGEQLGMVKRVKGDVMAVGAKELIELPQEVIQDRFNVSKDEGCAWLFAGSPANGLMGGGFIYTNKNSVSLGIVCGL
HDIGSSSKTVPQMLEDFKNHAMIKPLIEGGKLLEYSGHVVPEAGINMVPKLVDDGVLIAGDAAGFCLNLGYTVRGMDLAI
ASGEAAAKAVLAAREKNDFSAEGLSSYQTLLEDSFIMKDLKLYKDLPAFMETPRIFNQYPKMVADIMQSMFTVDGTPSQP
IRKTLMKHCKEVGYMNLIKDGIKGVTSI

Specific function: Could be part of an electron transfer system required for anaerobic carnitine reduction [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=407, Percent_Identity=26.2899262899263, Blast_Score=105, Evalue=1e-22,
Organism=Escherichia coli, GI1786227, Length=427, Percent_Identity=62.5292740046838, Blast_Score=550, Evalue=1e-158,
Organism=Escherichia coli, GI1787991, Length=429, Percent_Identity=61.3053613053613, Blast_Score=548, Evalue=1e-157,
Organism=Escherichia coli, GI87082155, Length=417, Percent_Identity=35.9712230215827, Blast_Score=294, Evalue=8e-81,
Organism=Caenorhabditis elegans, GI25144720, Length=399, Percent_Identity=26.5664160401003, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324932, Length=418, Percent_Identity=26.0765550239234, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24652256, Length=403, Percent_Identity=27.2952853598015, Blast_Score=108, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.5.5.-

Molecular weight: Translated: 46219; Mature: 46088

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEESFDAIIVGAGLAGCVAAYVLAKEGADVLVIERGNFAGSKNMTGGRLYAHSLEKIIP
CCCCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
GFAKEAPIERKVTKEKVTFLTDDTGVTLDYHNGREQNSTQESYTLLRGDFDQWLMGKAEE
CHHHCCCCHHHHHHHHEEEEECCCCEEEEECCCCCCCCCHHHHHHHHCCHHHHHCCCHHH
VGAQFITGIRVEEILTQDGKVIGVKADGDELTAKSVILAEGVNPILGEQLGMVKRVKGDV
HHHHHHHCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCE
MAVGAKELIELPQEVIQDRFNVSKDEGCAWLFAGSPANGLMGGGFIYTNKNSVSLGIVCG
EEECHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCEEEEEEEE
LHDIGSSSKTVPQMLEDFKNHAMIKPLIEGGKLLEYSGHVVPEAGINMVPKLVDDGVLIA
CHHCCCCCCHHHHHHHHHHCCCEEHHHHCCCCEEEECCCCCCCCCCHHHHHHHCCCEEEE
GDAAGFCLNLGYTVRGMDLAIASGEAAAKAVLAAREKNDFSAEGLSSYQTLLEDSFIMKD
CCCCCEEEECCEEEECCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LKLYKDLPAFMETPRIFNQYPKMVADIMQSMFTVDGTPSQPIRKTLMKHCKEVGYMNLIK
HHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHH
DGIKGVTSI
HHHHHHCCC
>Mature Secondary Structure 
SEESFDAIIVGAGLAGCVAAYVLAKEGADVLVIERGNFAGSKNMTGGRLYAHSLEKIIP
CCCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
GFAKEAPIERKVTKEKVTFLTDDTGVTLDYHNGREQNSTQESYTLLRGDFDQWLMGKAEE
CHHHCCCCHHHHHHHHEEEEECCCCEEEEECCCCCCCCCHHHHHHHHCCHHHHHCCCHHH
VGAQFITGIRVEEILTQDGKVIGVKADGDELTAKSVILAEGVNPILGEQLGMVKRVKGDV
HHHHHHHCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCE
MAVGAKELIELPQEVIQDRFNVSKDEGCAWLFAGSPANGLMGGGFIYTNKNSVSLGIVCG
EEECHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCEEEEEEEE
LHDIGSSSKTVPQMLEDFKNHAMIKPLIEGGKLLEYSGHVVPEAGINMVPKLVDDGVLIA
CHHCCCCCCHHHHHHHHHHCCCEEHHHHCCCCEEEECCCCCCCCCCHHHHHHHCCCEEEE
GDAAGFCLNLGYTVRGMDLAIASGEAAAKAVLAAREKNDFSAEGLSSYQTLLEDSFIMKD
CCCCCEEEECCEEEECCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LKLYKDLPAFMETPRIFNQYPKMVADIMQSMFTVDGTPSQPIRKTLMKHCKEVGYMNLIK
HHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHH
DGIKGVTSI
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]