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The map label for this gene is fixB [H]

Identifier: 167622159

GI number: 167622159

Start: 262827

End: 263768

Strand: Reverse

Name: fixB [H]

Synonym: Shal_0218

Alternate gene names: 167622159

Gene position: 263768-262827 (Counterclockwise)

Preceding gene: 167622160

Following gene: 167622158

Centisome position: 5.05

GC content: 47.24

Gene sequence:

>942_bases
ATGAGCAAACTATCTAATATTTGGGTATTTAGCGATATCGCTTCCCGTTTACCTGAAATGATCGCGGCTGGCGTAGCGTT
AGGCGAAAAAGTATCAACATTTGTAATCGGTACTGAAGCCGATATCAATGCAGCATTCTCATATGGTGCAACCCATGTGT
ACTATCTTGGCGACAAAGACAGCCAGAAGATCACCGAAGATTACAGTCACACCATGGCGCAGACTATTTCAGCTGCAGCA
GAAAACACACTAATGCTACTTGCACCCACTAAGCGTGGTAAAGCACTGGCAAGTAAGCTAGGTGTGCAGCTACAAGCAGG
TGTCGTTAACGATGTTATTGAGATCAGCATTGAAGACGGTATCCGCGCTAAGCATATGGCCTACGGTGGTTTGGCTATCG
CAGAAGAGAAAATCAATAGCCCAGTAGCCATTATCACCCTCAGCAGCGGTGCATATGAAGTGCAAGCTGCAGATACCGCT
CGCACTGGTGAAGCCGTTAGTGTGGCATTTGTAGAGCCTGCATCAACTATCAAGTGCGTAGAGCGCCGTGCTAAACAAGG
CGAGAGTGTAAACCTAGGCAAAGCTAAGCGTGTTGTCGGTGTCGGTAACGGTATTGGCAGCCAGGAAAACCTACAGGTTG
CGGCAGAACTTAGTGCACTGATGGGTGCCGAGCTAGGTTGCTCACGTCCTATCGCTGAAACCGAGAAATGGATGGAACGT
GAGCGCTATATCGGTGTTTCAGGCGTGATGTTAAAGCCAGAAATATACTTCGCACTGGGTATCTCAGGCCAAATTCAACA
CATGGTAGGTGCTTTAGGTTCACAAACAATCTTTGCCGTAAACAAAGATAAAAATGCGCCTATTTTCCAATACGTTGATT
ACGGCATTGTCGGCGACGTCAACAAGATCATGCCTGCACTAATCAGCGCCTTAAAAGCCTAA

Upstream 100 bases:

>100_bases
AAAGCACGTCAGAAGATCGTTATCGAAGGTGATGACGAGCAGCAGATCGCCCAATTCGCAGAACACTTACGTAACGCACT
TAACTAATTAAGGATAAATG

Downstream 100 bases:

>100_bases
TCAAAGCACAATTTTTATTGTTCTTTCAATCGCCTCTTATCCTAGTAGAGACAAGAGGCGAATAGCCAAATTTATGTAGA
GAGTGACGAGTATGTCAGAA

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSKLSNIWVFSDIASRLPEMIAAGVALGEKVSTFVIGTEADINAAFSYGATHVYYLGDKDSQKITEDYSHTMAQTISAAA
ENTLMLLAPTKRGKALASKLGVQLQAGVVNDVIEISIEDGIRAKHMAYGGLAIAEEKINSPVAIITLSSGAYEVQAADTA
RTGEAVSVAFVEPASTIKCVERRAKQGESVNLGKAKRVVGVGNGIGSQENLQVAAELSALMGAELGCSRPIAETEKWMER
ERYIGVSGVMLKPEIYFALGISGQIQHMVGALGSQTIFAVNKDKNAPIFQYVDYGIVGDVNKIMPALISALKA

Sequences:

>Translated_313_residues
MSKLSNIWVFSDIASRLPEMIAAGVALGEKVSTFVIGTEADINAAFSYGATHVYYLGDKDSQKITEDYSHTMAQTISAAA
ENTLMLLAPTKRGKALASKLGVQLQAGVVNDVIEISIEDGIRAKHMAYGGLAIAEEKINSPVAIITLSSGAYEVQAADTA
RTGEAVSVAFVEPASTIKCVERRAKQGESVNLGKAKRVVGVGNGIGSQENLQVAAELSALMGAELGCSRPIAETEKWMER
ERYIGVSGVMLKPEIYFALGISGQIQHMVGALGSQTIFAVNKDKNAPIFQYVDYGIVGDVNKIMPALISALKA
>Mature_312_residues
SKLSNIWVFSDIASRLPEMIAAGVALGEKVSTFVIGTEADINAAFSYGATHVYYLGDKDSQKITEDYSHTMAQTISAAAE
NTLMLLAPTKRGKALASKLGVQLQAGVVNDVIEISIEDGIRAKHMAYGGLAIAEEKINSPVAIITLSSGAYEVQAADTAR
TGEAVSVAFVEPASTIKCVERRAKQGESVNLGKAKRVVGVGNGIGSQENLQVAAELSALMGAELGCSRPIAETEKWMERE
RYIGVSGVMLKPEIYFALGISGQIQHMVGALGSQTIFAVNKDKNAPIFQYVDYGIVGDVNKIMPALISALKA

Specific function: Required for anaerobic carnitine reduction. May bring reductant to CaiA [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=220, Percent_Identity=30.4545454545455, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI189181759, Length=220, Percent_Identity=30.4545454545455, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1786226, Length=312, Percent_Identity=54.1666666666667, Blast_Score=345, Evalue=2e-96,
Organism=Escherichia coli, GI1787990, Length=312, Percent_Identity=52.2435897435897, Blast_Score=323, Evalue=1e-89,
Organism=Escherichia coli, GI87082157, Length=122, Percent_Identity=35.2459016393443, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=302, Percent_Identity=28.8079470198675, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6325261, Length=127, Percent_Identity=33.0708661417323, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17136898, Length=230, Percent_Identity=31.304347826087, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24652801, Length=230, Percent_Identity=31.304347826087, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 33159; Mature: 33028

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLSNIWVFSDIASRLPEMIAAGVALGEKVSTFVIGTEADINAAFSYGATHVYYLGDKD
CCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEECCCEEEEEECCCC
SQKITEDYSHTMAQTISAAAENTLMLLAPTKRGKALASKLGVQLQAGVVNDVIEISIEDG
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCEEECCHHCCEEEEEECCC
IRAKHMAYGGLAIAEEKINSPVAIITLSSGAYEVQAADTARTGEAVSVAFVEPASTIKCV
CCCHHEECCCEEEEHHHCCCCEEEEEECCCCEEEEECCCCCCCCEEEEEEECCHHHHHHH
ERRAKQGESVNLGKAKRVVGVGNGIGSQENLQVAAELSALMGAELGCSRPIAETEKWMER
HHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
ERYIGVSGVMLKPEIYFALGISGQIQHMVGALGSQTIFAVNKDKNAPIFQYVDYGIVGDV
HHCCCCCCEEECCEEEEEEECCCHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCH
NKIMPALISALKA
HHHHHHHHHHHCC
>Mature Secondary Structure 
SKLSNIWVFSDIASRLPEMIAAGVALGEKVSTFVIGTEADINAAFSYGATHVYYLGDKD
CCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEECCCEEEEEECCCC
SQKITEDYSHTMAQTISAAAENTLMLLAPTKRGKALASKLGVQLQAGVVNDVIEISIEDG
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCEEECCHHCCEEEEEECCC
IRAKHMAYGGLAIAEEKINSPVAIITLSSGAYEVQAADTARTGEAVSVAFVEPASTIKCV
CCCHHEECCCEEEEHHHCCCCEEEEEECCCCEEEEECCCCCCCCEEEEEEECCHHHHHHH
ERRAKQGESVNLGKAKRVVGVGNGIGSQENLQVAAELSALMGAELGCSRPIAETEKWMER
HHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
ERYIGVSGVMLKPEIYFALGISGQIQHMVGALGSQTIFAVNKDKNAPIFQYVDYGIVGDV
HHCCCCCCEEECCEEEEEEECCCHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCH
NKIMPALISALKA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA