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The map label for this gene is alsA [C]

Identifier: 167622098

GI number: 167622098

Start: 183782

End: 185233

Strand: Direct

Name: alsA [C]

Synonym: Shal_0157

Alternate gene names: 167622098

Gene position: 183782-185233 (Clockwise)

Preceding gene: 167622097

Following gene: 167622099

Centisome position: 3.52

GC content: 47.66

Gene sequence:

>1452_bases
ATGAAACTCATAGCACTAGAAGGGATTCATTTTGGCTATGGATCGCACCAAAGCGAGATCTTGGACGATCTCAATTTGGT
GGTTAATCGTGGGGAATGCCACTGTATTAACGGTCCGACAGGCTCTGGCAAATCAAGCTTATTGCACTTGATGGCTGGAG
AGCTTTCTCGACCCTATGAGGGGGAGGTTTATCGAGCTCCCTCATTGCTGGTCGGTTTAGTGATGCAAGATCCTAATGTG
CAGATTTTGCGTCAAAGTGTTGGGGCCGAAATTGCTTTTGGACTCGAAAACCTCGGTATTGCCGCCGAGCTCATGGTTGA
AAAGGTGCAGCAGTCACTGAGGCGAGTAGGGCTTTATATCAGCCTAGATACGCCGGTTGAAGTCTTGTCATTAGGGCAGA
AGTACCGTCTTATGATTGCGGCGCAGCTAGTGTTTAAGCCATCTTTATTACTGCTCGATGAACCCTGGGCCCAGCTTGAT
GACAGTGGTGTGAAAGAGCTGTATGCCGTGCTCAAAACCCTGTTAGATGACGGCGTTGCTGTCGTGATGGTTGAACACAA
CCCCGGCGCATTTTTGGACTTAGTCGATTATCTATGGTTACTTAAAGATGGGTTACTTAAAGACGGGTTACTTAAAGACG
GGCAGCTCGAAGAAGGGCGACTCGATGCGGGTCAGAATGACCCTAGCAACGTTGCAGTGAACAACGTTGCAGCGAGCAAT
GAGCAAGTGTTTGATAAAGAAGATGTTGTTAGTCTTAAATCTCGTTTTAGCTTCGATAACAGCGAATGTCTAATCAAAAT
TCAGCCACATCATTTTCGGTTTATAGAGCAAGAGTGTCTCTTCGATTGCCAACAAAGCTTGTCACTTTATAGCGGTGAGG
TTGTCGCTTTGGTTGGTGATAATGGGGTCGGTAAGAGTAGTTTACTCAAAACACTGGCGGGTATTCAGGCCAATATTCCA
ACCTTTCCTATCTCGGTATTGGGTAAGCGTCCACGACTCGGGATCTACGGCGCCGAGCTTGGTCTGCTGATGCAGCGCCC
AAATCGTCAGCTATTTGAACAAACTGTGCAGGCTGAGCTGCAGTTTAGTTTGAAGCGTTTCAAGCTGCCGTTATCTCGTG
CTGAGCAGGTGCTACAAGCATTGGAGCTCACCCATCTAGCCGAGAGTTCGCCGCATAAACTGTCTTACGGTCAGCAGCAT
ATTATCGCCTTGGCGTCTCTGGTTTGCTTGCAGCCTAAGGTTTTATTGCTTGATGACCCTTTTGCAGGACTCGATAAGCA
ACATGTAGAAAAAGTGGTTCTGTTGCTACAGCAGCTGAGTATGCAAGGTTGCGGGATCTTGCTGACTAGTCACCGCGCGA
TCCCATCACTTGATGTTGATCGTTACTGGTTGATCGAATCAGGAAAGCTGATGGATGGAGCTGGACATATTGAGCAATTG
AATGTGGGCTAA

Upstream 100 bases:

>100_bases
TATTTGATGAGCTTTATTATCAAAGTGACTTTATGCCACAGGCGGGTCGTCAGGTATTCATCGGCATTAACTGGCAGGTT
TAGGTCTTTCGGGGAAAAGT

Downstream 100 bases:

>100_bases
TCGTCACATACGCCGAGGCGTCAACAAGCGTTCAGACACGATCCATTCAAGCTTTAGTTTGAGTGCGACCCAATACTGTG
CAGTGGCGTTAGTGCTGAGC

Product: ABC transporter-like protein

Products: ADP; phosphate; ribose [Cytoplasm]; D-allose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MKLIALEGIHFGYGSHQSEILDDLNLVVNRGECHCINGPTGSGKSSLLHLMAGELSRPYEGEVYRAPSLLVGLVMQDPNV
QILRQSVGAEIAFGLENLGIAAELMVEKVQQSLRRVGLYISLDTPVEVLSLGQKYRLMIAAQLVFKPSLLLLDEPWAQLD
DSGVKELYAVLKTLLDDGVAVVMVEHNPGAFLDLVDYLWLLKDGLLKDGLLKDGQLEEGRLDAGQNDPSNVAVNNVAASN
EQVFDKEDVVSLKSRFSFDNSECLIKIQPHHFRFIEQECLFDCQQSLSLYSGEVVALVGDNGVGKSSLLKTLAGIQANIP
TFPISVLGKRPRLGIYGAELGLLMQRPNRQLFEQTVQAELQFSLKRFKLPLSRAEQVLQALELTHLAESSPHKLSYGQQH
IIALASLVCLQPKVLLLDDPFAGLDKQHVEKVVLLLQQLSMQGCGILLTSHRAIPSLDVDRYWLIESGKLMDGAGHIEQL
NVG

Sequences:

>Translated_483_residues
MKLIALEGIHFGYGSHQSEILDDLNLVVNRGECHCINGPTGSGKSSLLHLMAGELSRPYEGEVYRAPSLLVGLVMQDPNV
QILRQSVGAEIAFGLENLGIAAELMVEKVQQSLRRVGLYISLDTPVEVLSLGQKYRLMIAAQLVFKPSLLLLDEPWAQLD
DSGVKELYAVLKTLLDDGVAVVMVEHNPGAFLDLVDYLWLLKDGLLKDGLLKDGQLEEGRLDAGQNDPSNVAVNNVAASN
EQVFDKEDVVSLKSRFSFDNSECLIKIQPHHFRFIEQECLFDCQQSLSLYSGEVVALVGDNGVGKSSLLKTLAGIQANIP
TFPISVLGKRPRLGIYGAELGLLMQRPNRQLFEQTVQAELQFSLKRFKLPLSRAEQVLQALELTHLAESSPHKLSYGQQH
IIALASLVCLQPKVLLLDDPFAGLDKQHVEKVVLLLQQLSMQGCGILLTSHRAIPSLDVDRYWLIESGKLMDGAGHIEQL
NVG
>Mature_483_residues
MKLIALEGIHFGYGSHQSEILDDLNLVVNRGECHCINGPTGSGKSSLLHLMAGELSRPYEGEVYRAPSLLVGLVMQDPNV
QILRQSVGAEIAFGLENLGIAAELMVEKVQQSLRRVGLYISLDTPVEVLSLGQKYRLMIAAQLVFKPSLLLLDEPWAQLD
DSGVKELYAVLKTLLDDGVAVVMVEHNPGAFLDLVDYLWLLKDGLLKDGLLKDGQLEEGRLDAGQNDPSNVAVNNVAASN
EQVFDKEDVVSLKSRFSFDNSECLIKIQPHHFRFIEQECLFDCQQSLSLYSGEVVALVGDNGVGKSSLLKTLAGIQANIP
TFPISVLGKRPRLGIYGAELGLLMQRPNRQLFEQTVQAELQFSLKRFKLPLSRAEQVLQALELTHLAESSPHKLSYGQQH
IIALASLVCLQPKVLLLDDPFAGLDKQHVEKVVLLLQQLSMQGCGILLTSHRAIPSLDVDRYWLIESGKLMDGAGHIEQL
NVG

Specific function: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system [H]

COG id: COG1122

COG function: function code P; ABC-type cobalt transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI215820660, Length=192, Percent_Identity=29.6875, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI20143975, Length=192, Percent_Identity=29.6875, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI46592978, Length=190, Percent_Identity=29.4736842105263, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI46592915, Length=190, Percent_Identity=29.4736842105263, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI46592898, Length=190, Percent_Identity=29.4736842105263, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI46592964, Length=190, Percent_Identity=29.4736842105263, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI46592956, Length=190, Percent_Identity=29.4736842105263, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI46592971, Length=190, Percent_Identity=29.4736842105263, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI31657092, Length=185, Percent_Identity=28.6486486486486, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI11967969, Length=203, Percent_Identity=30.0492610837438, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1790525, Length=526, Percent_Identity=24.3346007604563, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789991, Length=502, Percent_Identity=24.9003984063745, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788897, Length=486, Percent_Identity=23.4567901234568, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788506, Length=483, Percent_Identity=24.6376811594203, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1787792, Length=493, Percent_Identity=24.1379310344828, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786563, Length=192, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI87081791, Length=183, Percent_Identity=32.2404371584699, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788210, Length=487, Percent_Identity=23.4086242299795, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788472, Length=512, Percent_Identity=21.2890625, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87081709, Length=212, Percent_Identity=25.4716981132075, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787370, Length=221, Percent_Identity=30.316742081448, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787105, Length=206, Percent_Identity=29.126213592233, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789593, Length=201, Percent_Identity=27.8606965174129, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790190, Length=180, Percent_Identity=29.4444444444444, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786975, Length=494, Percent_Identity=23.6842105263158, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786872, Length=207, Percent_Identity=28.9855072463768, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788761, Length=197, Percent_Identity=29.9492385786802, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787029, Length=219, Percent_Identity=29.2237442922374, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081834, Length=198, Percent_Identity=29.2929292929293, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI48995001, Length=174, Percent_Identity=29.8850574712644, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790467, Length=218, Percent_Identity=28.4403669724771, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787089, Length=204, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788225, Length=201, Percent_Identity=24.8756218905473, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787712, Length=201, Percent_Identity=30.3482587064677, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788165, Length=188, Percent_Identity=30.8510638297872, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789873, Length=195, Percent_Identity=28.7179487179487, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87082267, Length=152, Percent_Identity=29.6052631578947, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786319, Length=181, Percent_Identity=29.2817679558011, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786703, Length=201, Percent_Identity=28.8557213930348, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789751, Length=244, Percent_Identity=30.327868852459, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1787500, Length=180, Percent_Identity=27.2222222222222, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1789672, Length=203, Percent_Identity=24.6305418719212, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1789891, Length=183, Percent_Identity=31.1475409836066, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1787547, Length=211, Percent_Identity=26.5402843601896, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17559834, Length=202, Percent_Identity=26.7326732673267, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6320214, Length=192, Percent_Identity=30.7291666666667, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324398, Length=193, Percent_Identity=30.5699481865285, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574744, Length=218, Percent_Identity=30.7339449541284, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI161076682, Length=200, Percent_Identity=32, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI161076684, Length=200, Percent_Identity=32, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24581617, Length=200, Percent_Identity=32, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24581615, Length=200, Percent_Identity=32, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19920532, Length=205, Percent_Identity=31.7073170731707, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24580930, Length=205, Percent_Identity=31.7073170731707, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI85724864, Length=207, Percent_Identity=30.4347826086957, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24580555, Length=207, Percent_Identity=30.4347826086957, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI85816269, Length=206, Percent_Identity=30.5825242718447, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24580553, Length=206, Percent_Identity=30.5825242718447, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI85724858, Length=211, Percent_Identity=30.3317535545024, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI85724856, Length=211, Percent_Identity=30.3317535545024, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24580547, Length=211, Percent_Identity=30.3317535545024, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24580551, Length=211, Percent_Identity=30.3317535545024, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24580549, Length=211, Percent_Identity=30.3317535545024, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24580545, Length=211, Percent_Identity=30.3317535545024, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581191, Length=193, Percent_Identity=26.4248704663212, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581189, Length=193, Percent_Identity=26.4248704663212, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581193, Length=193, Percent_Identity=26.4248704663212, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581195, Length=193, Percent_Identity=26.4248704663212, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574533, Length=215, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR003339 [H]

Pfam domain/function: PF00005 ABC_tran; PF02361 CbiQ [H]

EC number: NA

Molecular weight: Translated: 53137; Mature: 53137

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIALEGIHFGYGSHQSEILDDLNLVVNRGECHCINGPTGSGKSSLLHLMAGELSRPYE
CEEEEEECEECCCCCCHHHHHHHHHHEEECCCEEEECCCCCCCHHHHHHHHHHHCCCCCC
GEVYRAPSLLVGLVMQDPNVQILRQSVGAEIAFGLENLGIAAELMVEKVQQSLRRVGLYI
CCEEECCHHHEEEEECCCCHHHHHHHHCCEEEECHHHCCHHHHHHHHHHHHHHHHCEEEE
SLDTPVEVLSLGQKYRLMIAAQLVFKPSLLLLDEPWAQLDDSGVKELYAVLKTLLDDGVA
EECCCHHHHHCCCHHHHHHHHHHHHCCCEEEEECCHHHCCCCCHHHHHHHHHHHHCCCEE
VVMVEHNPGAFLDLVDYLWLLKDGLLKDGLLKDGQLEEGRLDAGQNDPSNVAVNNVAASN
EEEEECCCCHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECEECCC
EQVFDKEDVVSLKSRFSFDNSECLIKIQPHHFRFIEQECLFDCQQSLSLYSGEVVALVGD
CCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
NGVGKSSLLKTLAGIQANIPTFPISVLGKRPRLGIYGAELGLLMQRPNRQLFEQTVQAEL
CCCCHHHHHHHHHCCCCCCCCCCHHHCCCCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHH
QFSLKRFKLPLSRAEQVLQALELTHLAESSPHKLSYGQQHIIALASLVCLQPKVLLLDDP
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECC
FAGLDKQHVEKVVLLLQQLSMQGCGILLTSHRAIPSLDVDRYWLIESGKLMDGAGHIEQL
CCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEECCCEECCCCCCEEE
NVG
CCC
>Mature Secondary Structure
MKLIALEGIHFGYGSHQSEILDDLNLVVNRGECHCINGPTGSGKSSLLHLMAGELSRPYE
CEEEEEECEECCCCCCHHHHHHHHHHEEECCCEEEECCCCCCCHHHHHHHHHHHCCCCCC
GEVYRAPSLLVGLVMQDPNVQILRQSVGAEIAFGLENLGIAAELMVEKVQQSLRRVGLYI
CCEEECCHHHEEEEECCCCHHHHHHHHCCEEEECHHHCCHHHHHHHHHHHHHHHHCEEEE
SLDTPVEVLSLGQKYRLMIAAQLVFKPSLLLLDEPWAQLDDSGVKELYAVLKTLLDDGVA
EECCCHHHHHCCCHHHHHHHHHHHHCCCEEEEECCHHHCCCCCHHHHHHHHHHHHCCCEE
VVMVEHNPGAFLDLVDYLWLLKDGLLKDGLLKDGQLEEGRLDAGQNDPSNVAVNNVAASN
EEEEECCCCHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECEECCC
EQVFDKEDVVSLKSRFSFDNSECLIKIQPHHFRFIEQECLFDCQQSLSLYSGEVVALVGD
CCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
NGVGKSSLLKTLAGIQANIPTFPISVLGKRPRLGIYGAELGLLMQRPNRQLFEQTVQAEL
CCCCHHHHHHHHHCCCCCCCCCCHHHCCCCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHH
QFSLKRFKLPLSRAEQVLQALELTHLAESSPHKLSYGQQHIIALASLVCLQPKVLLLDDP
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECC
FAGLDKQHVEKVVLLLQQLSMQGCGILLTSHRAIPSLDVDRYWLIESGKLMDGAGHIEQL
CCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEECCCEECCCCCCEEE
NVG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; ribose [Periplasm]; D-allose [Periplasm]; ATP [C]

Specific reaction: ATP + H2O + ribose [Periplasm] = ADP + phosphate + ribose [Cytoplasm] D-allose [Periplasm] + ATP + H2O = D-allose [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]