Click here to switch to the map view.

The map label for this gene is fepA [H]

Identifier: 167622097

GI number: 167622097

Start: 181815

End: 183764

Strand: Direct

Name: fepA [H]

Synonym: Shal_0156

Alternate gene names: 167622097

Gene position: 181815-183764 (Clockwise)

Preceding gene: 167622092

Following gene: 167622098

Centisome position: 3.48

GC content: 42.62

Gene sequence:

>1950_bases
ATGAAAAAGCAACAAAAGGTGCTGAGAGTATCCACTCTTGCATTGGCGATGGGCTTGGCCTATCAAGTTCAAGCAGATGA
CCTAGAAAGAGACCCTATTTTTAATGTATCTGAAGTGATTGTGGTGCATGGTGAGCGTGCTTCTGTTACTGAGGCAGCGA
CAACAAATTGGAGCATCGATGCTGAGGAGATCAAGGCATCAGGAGCGCAGAGCTTAGACCAAGTACTTGAAAACGTACCG
GGGATATATGTTCGAGTCGGTGGAGATTCAACCCCTCGAGTTGATATTCGAGGTTTAAAAACACGTCACATTACTTTCCT
AATTAACGGCGTTCCCGCAAGTAGCACTGAAGACGGTCAGTTTGATCCAAGTGTTATCCCAACAAATCAAATTGCCCGAG
TTGATGTATCTGTTGGTCCGTCATCCGTGTTGTACGGCCCAGGCGGAAGCGCGGGTGTCATTAATATTATTACTAAGCAA
GGTGATAATGCGTCAGCTTTCTCTGGTCGCCTAGAAGCGGCACAAGACAACACCTTTAATGGTGATTTAAGCGCCGCGGG
TTCAGGTGACAACTGGCAAGGTATTATGAGCGTTACTCATCAAGAAACTGATGGCACTCCAATGCCTGATGATTTTGAAG
ATACGCGTAATCAAATCGGTGATGTGCGTTTTAACTCCGATAGGAAATTAACTAACTATTATGCGCAAGGTAGTTACTTC
ATCAACGATTCAACTAAGTTAATGGCCAACTACACTCAACGTGATGGTGAGTGGGGCAAATCGCCTACAGTTGATCGTAA
AAAAGCCCCATCAAGAATTGAAGATTTCAACGAACAAAGTATGCAACTTGGTGCGGCACATGAAATAAACGAGCAGTATG
TTGTTCGTGGTTTTGTTTATTATAACCAAACAGATATGGTTGAGAATTTCTATAACCATAGAATGAATAACTTAAATAGT
ATTGTTAAAAGTACCTCTAAAGTCAGCGGCACTAATCTTCAATTTATTAGCGAATTTGATTATGGCGCTGTGTTGACCAC
TTCTGTCATTGTTGAAAAGCAAGATTGGTTCTCTCATACAAATAAACTTCGTAGCGATAAAGGAACAGGCAGCGGTGGCG
GCACTGGCGGCGGTCAAGGCGGGTCAGGTGATATCGATGAAAGCCTTATTGTTTATACCGGTGCTGCAGAGTATCAATAT
CAAGATGACGGCAAATATGGCTACAGCTTAGGTGTAGCGGTACACAATTACGATCTTGATGTGAACAGTGAGACAGATTT
TTCAGTGCAAGCGTCTGCATTTTATCAAGCCACTGACTCAAGCCGTATCCATACAGGTCTTGCTCGAAAAGTACGTTATC
CATCAATCAGCGATCTTTACGCGGCTAACAGCGGTAACGTGAACCTAAAAGCGGAAGTTGCTAACCAGTTTGAACTGGGT
CTACAGCAATCTCTACCTTTCGATACTCAGCTAGATATCAGTAGCTATATTACTGATGCCAATGATTACATAGCTAAAGA
TGATAACAACCAAGAGCAAAACATTGGTGATTTTCGCTTTATGGGTGTTGATTTGCAGATGACGAATCAATATTTCGATA
GCCTAGGGGTAACGTTTGCCTATAGCTACATTGATACCGAAGATCGTGCTACCAATGAACGTTTGCAATACCGTCCGACT
CACAATCTGCGCCTGCAAGCGAGTTATGATTTTTCCTTCGGTTTAACGACACGTTTAAACGCTGAACGCATAATTGATCA
AGTGAACGGCAAAGGTGTTCAATTAGATAATTACACCTTAGTCGATCTAAGTTTGAGTCAAAATATTTGGCATGACAATT
TAGAGTTATACGTCCGAGCGACGAACCTATTTGATGAGCTTTATTATCAAAGTGACTTTATGCCACAGGCGGGTCGTCAG
GTATTCATCGGCATTAACTGGCAGGTTTAG

Upstream 100 bases:

>100_bases
ATTAGTCGATCCAGGTTTGTTTTATGATTTTATTTACTTGAGTGTTGGTCAGTGCTTTTTGAAAATAACAAAAAATAAAT
CGTTAGGATGATGAAATCAG

Downstream 100 bases:

>100_bases
GTCTTTCGGGGAAAAGTATGAAACTCATAGCACTAGAAGGGATTCATTTTGGCTATGGATCGCACCAAAGCGAGATCTTG
GACGATCTCAATTTGGTGGT

Product: TonB-dependent receptor plug

Products: NA

Alternate protein names: Enterobactin outer-membrane receptor [H]

Number of amino acids: Translated: 649; Mature: 649

Protein sequence:

>649_residues
MKKQQKVLRVSTLALAMGLAYQVQADDLERDPIFNVSEVIVVHGERASVTEAATTNWSIDAEEIKASGAQSLDQVLENVP
GIYVRVGGDSTPRVDIRGLKTRHITFLINGVPASSTEDGQFDPSVIPTNQIARVDVSVGPSSVLYGPGGSAGVINIITKQ
GDNASAFSGRLEAAQDNTFNGDLSAAGSGDNWQGIMSVTHQETDGTPMPDDFEDTRNQIGDVRFNSDRKLTNYYAQGSYF
INDSTKLMANYTQRDGEWGKSPTVDRKKAPSRIEDFNEQSMQLGAAHEINEQYVVRGFVYYNQTDMVENFYNHRMNNLNS
IVKSTSKVSGTNLQFISEFDYGAVLTTSVIVEKQDWFSHTNKLRSDKGTGSGGGTGGGQGGSGDIDESLIVYTGAAEYQY
QDDGKYGYSLGVAVHNYDLDVNSETDFSVQASAFYQATDSSRIHTGLARKVRYPSISDLYAANSGNVNLKAEVANQFELG
LQQSLPFDTQLDISSYITDANDYIAKDDNNQEQNIGDFRFMGVDLQMTNQYFDSLGVTFAYSYIDTEDRATNERLQYRPT
HNLRLQASYDFSFGLTTRLNAERIIDQVNGKGVQLDNYTLVDLSLSQNIWHDNLELYVRATNLFDELYYQSDFMPQAGRQ
VFIGINWQV

Sequences:

>Translated_649_residues
MKKQQKVLRVSTLALAMGLAYQVQADDLERDPIFNVSEVIVVHGERASVTEAATTNWSIDAEEIKASGAQSLDQVLENVP
GIYVRVGGDSTPRVDIRGLKTRHITFLINGVPASSTEDGQFDPSVIPTNQIARVDVSVGPSSVLYGPGGSAGVINIITKQ
GDNASAFSGRLEAAQDNTFNGDLSAAGSGDNWQGIMSVTHQETDGTPMPDDFEDTRNQIGDVRFNSDRKLTNYYAQGSYF
INDSTKLMANYTQRDGEWGKSPTVDRKKAPSRIEDFNEQSMQLGAAHEINEQYVVRGFVYYNQTDMVENFYNHRMNNLNS
IVKSTSKVSGTNLQFISEFDYGAVLTTSVIVEKQDWFSHTNKLRSDKGTGSGGGTGGGQGGSGDIDESLIVYTGAAEYQY
QDDGKYGYSLGVAVHNYDLDVNSETDFSVQASAFYQATDSSRIHTGLARKVRYPSISDLYAANSGNVNLKAEVANQFELG
LQQSLPFDTQLDISSYITDANDYIAKDDNNQEQNIGDFRFMGVDLQMTNQYFDSLGVTFAYSYIDTEDRATNERLQYRPT
HNLRLQASYDFSFGLTTRLNAERIIDQVNGKGVQLDNYTLVDLSLSQNIWHDNLELYVRATNLFDELYYQSDFMPQAGRQ
VFIGINWQV
>Mature_649_residues
MKKQQKVLRVSTLALAMGLAYQVQADDLERDPIFNVSEVIVVHGERASVTEAATTNWSIDAEEIKASGAQSLDQVLENVP
GIYVRVGGDSTPRVDIRGLKTRHITFLINGVPASSTEDGQFDPSVIPTNQIARVDVSVGPSSVLYGPGGSAGVINIITKQ
GDNASAFSGRLEAAQDNTFNGDLSAAGSGDNWQGIMSVTHQETDGTPMPDDFEDTRNQIGDVRFNSDRKLTNYYAQGSYF
INDSTKLMANYTQRDGEWGKSPTVDRKKAPSRIEDFNEQSMQLGAAHEINEQYVVRGFVYYNQTDMVENFYNHRMNNLNS
IVKSTSKVSGTNLQFISEFDYGAVLTTSVIVEKQDWFSHTNKLRSDKGTGSGGGTGGGQGGSGDIDESLIVYTGAAEYQY
QDDGKYGYSLGVAVHNYDLDVNSETDFSVQASAFYQATDSSRIHTGLARKVRYPSISDLYAANSGNVNLKAEVANQFELG
LQQSLPFDTQLDISSYITDANDYIAKDDNNQEQNIGDFRFMGVDLQMTNQYFDSLGVTFAYSYIDTEDRATNERLQYRPT
HNLRLQASYDFSFGLTTRLNAERIIDQVNGKGVQLDNYTLVDLSLSQNIWHDNLELYVRATNLFDELYYQSDFMPQAGRQ
VFIGINWQV

Specific function: This protein is involved in the initial step of iron uptake by binding ferrienterobactin (Fe-ENT), an iron chelatin siderophore that allows E.coli to extract iron from the environment. FepA also acts as a receptor for colicins B and D [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786798, Length=192, Percent_Identity=30.2083333333333, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788478, Length=164, Percent_Identity=29.8780487804878, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 71924; Mature: 71924

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQQKVLRVSTLALAMGLAYQVQADDLERDPIFNVSEVIVVHGERASVTEAATTNWSID
CCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCHHCCCCCCCC
AEEIKASGAQSLDQVLENVPGIYVRVGGDSTPRVDIRGLKTRHITFLINGVPASSTEDGQ
HHHHHCCCHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCEEEEEEEEECCCCCCCCCCC
FDPSVIPTNQIARVDVSVGPSSVLYGPGGSAGVINIITKQGDNASAFSGRLEAAQDNTFN
CCCCCCCCCCEEEEEEECCCCEEEECCCCCCCEEEEEEECCCCCCHHCCCEECCCCCCCC
GDLSAAGSGDNWQGIMSVTHQETDGTPMPDDFEDTRNQIGDVRFNSDRKLTNYYAQGSYF
CCEECCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCEEECCCCCEEEEEECCEEE
INDSTKLMANYTQRDGEWGKSPTVDRKKAPSRIEDFNEQSMQLGAAHEINEQYVVRGFVY
ECCCCEEEEEHHHCCCCCCCCCCCCCCCCCCHHHHCCHHHHHCCCHHHCCCEEEEEEEEE
YNQTDMVENFYNHRMNNLNSIVKSTSKVSGTNLQFISEFDYGAVLTTSVIVEKQDWFSHT
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEECHHHHHHH
NKLRSDKGTGSGGGTGGGQGGSGDIDESLIVYTGAAEYQYQDDGKYGYSLGVAVHNYDLD
HHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCCEEEEEEEEEEEEC
VNSETDFSVQASAFYQATDSSRIHTGLARKVRYPSISDLYAANSGNVNLKAEVANQFELG
CCCCCCCEEEEEEEEEECCCCHHHHHHHHHCCCCCCHHHEECCCCCEEEEEEECCHHHHC
LQQSLPFDTQLDISSYITDANDYIAKDDNNQEQNIGDFRFMGVDLQMTNQYFDSLGVTFA
HHHCCCCCCEECHHHHHCCCCCEEECCCCCCCCCCCCEEEEEEEEEEHHHHHHCCCCEEE
YSYIDTEDRATNERLQYRPTHNLRLQASYDFSFGLTTRLNAERIIDQVNGKGVQLDNYTL
EEEECCCCCCCCCCEEECCCCCEEEEEECCEEECCEECCCHHHHHHHCCCCCEEECCEEE
VDLSLSQNIWHDNLELYVRATNLFDELYYQSDFMPQAGRQVFIGINWQV
EEEECCCCCCCCCEEEEEEEHHHHHHHHHCCCCCCCCCCEEEEEEEEEC
>Mature Secondary Structure
MKKQQKVLRVSTLALAMGLAYQVQADDLERDPIFNVSEVIVVHGERASVTEAATTNWSID
CCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCHHCCCCCCCC
AEEIKASGAQSLDQVLENVPGIYVRVGGDSTPRVDIRGLKTRHITFLINGVPASSTEDGQ
HHHHHCCCHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCEEEEEEEEECCCCCCCCCCC
FDPSVIPTNQIARVDVSVGPSSVLYGPGGSAGVINIITKQGDNASAFSGRLEAAQDNTFN
CCCCCCCCCCEEEEEEECCCCEEEECCCCCCCEEEEEEECCCCCCHHCCCEECCCCCCCC
GDLSAAGSGDNWQGIMSVTHQETDGTPMPDDFEDTRNQIGDVRFNSDRKLTNYYAQGSYF
CCEECCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCEEECCCCCEEEEEECCEEE
INDSTKLMANYTQRDGEWGKSPTVDRKKAPSRIEDFNEQSMQLGAAHEINEQYVVRGFVY
ECCCCEEEEEHHHCCCCCCCCCCCCCCCCCCHHHHCCHHHHHCCCHHHCCCEEEEEEEEE
YNQTDMVENFYNHRMNNLNSIVKSTSKVSGTNLQFISEFDYGAVLTTSVIVEKQDWFSHT
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEECHHHHHHH
NKLRSDKGTGSGGGTGGGQGGSGDIDESLIVYTGAAEYQYQDDGKYGYSLGVAVHNYDLD
HHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCCEEEEEEEEEEEEC
VNSETDFSVQASAFYQATDSSRIHTGLARKVRYPSISDLYAANSGNVNLKAEVANQFELG
CCCCCCCEEEEEEEEEECCCCHHHHHHHHHCCCCCCHHHEECCCCCEEEEEEECCHHHHC
LQQSLPFDTQLDISSYITDANDYIAKDDNNQEQNIGDFRFMGVDLQMTNQYFDSLGVTFA
HHHCCCCCCEECHHHHHCCCCCEEECCCCCCCCCCCCEEEEEEEEEEHHHHHHCCCCEEE
YSYIDTEDRATNERLQYRPTHNLRLQASYDFSFGLTTRLNAERIIDQVNGKGVQLDNYTL
EEEECCCCCCCCCCEEECCCCCEEEEEECCEEECCEECCCHHHHHHHCCCCCEEECCEEE
VDLSLSQNIWHDNLELYVRATNLFDELYYQSDFMPQAGRQVFIGINWQV
EEEECCCCCCCCCEEEEEEEHHHHHHHHHCCCCCCCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3015941; 8905232; 9278503; 2974033; 2526281; 2201687; 9886293 [H]