Click here to switch to the map view.

The map label for this gene is atoS [H]

Identifier: 167622092

GI number: 167622092

Start: 169773

End: 171911

Strand: Direct

Name: atoS [H]

Synonym: Shal_0151

Alternate gene names: 167622092

Gene position: 169773-171911 (Clockwise)

Preceding gene: 167622091

Following gene: 167622097

Centisome position: 3.25

GC content: 46.52

Gene sequence:

>2139_bases
GTGTCGTTTTTTTCCAATATGTTTGGTGTGAGTTGGCAGCAGATGCAGGCGAAGGTGCGTTATCGTATCTTGATTTTGAC
CTTGTTGCCTATCCTACTCACACTTGTGAGTTTGGTTTTTATTACTATCTATTGGAATATAAGCTATACGGGTAAGCAGC
TGTTTATGAAGGTCAAAGCCGATTTGACCGTCGCCAATAGCACCTTGATAACCGTTCAAGACAATCAAGAGAAACAGCTT
GAGCTGGTGATGGAATCTTGGCCATTTCAGAATGATTTTCGTCAAATAGGTAACCACCCCACCCTGCAGCGCAATAATCT
GCAACAGGTTTTGGATAAGGCAAAAAAAGACCTTAACTTAGATTTCTTACGTTTAGTCAGTGTGTCCGAGGCTGCAGCTG
ACCCCGATCTTAGGCAGATGCTGCCGCATATTGAAGGATTAGCACCTTTTTCTGGGTTAATGGTGCTCGAACCAAGTCGT
TTATCTCGCATCGACCCAGAGCTCGCTGAAAGAGCGGAAGTGACCGTCATTAAGACCTTGCGGGCACATGAGCCAAATAA
ACACGAAGAGAAGCGTGGCCTGTTAAGCAGAAGCTTGCTGCCAGTTGCCGATATTAATGGCAATGTGGCTTGGTATCTAG
ATGGCGGCATCATGCTTAATCGTGATACGCGTATTGTCGACCATATTCGAGACTTAGTGTACGACAAAGGGACTTTGCCT
GAACGCTCTATCGGTACCGTCACCATTTTTCTCGATAATATCCGCATCAGTACCAATGTTCCGCTGCACTTTTTTCCACA
AGGCGATGATAAACAAGGTCGTGCGCTAGGTAGTTTGGTTTCATCTGAAGTACGCGAGAAGGTGCTAAATCAAGGGCTAC
TGTGGGTCGATAGAGCCTTTGTTTTTAACGACTGGTTTATCTCGGCCTATTCACCACTTAAAGATATTAACGGTAAGCGG
ATCGGTATGATCTATACCGGCTTCTCTGAATCCCCATTTATCCATAACTACTTACTCAACATTATTGAGCTCGGTACCAT
CTTGATGTTGGTGCTGCTGGTATCGGGTTGGTTGGTATATCGTGGTGCCTACAGTTTATTGCAACCGATTGAGCGTATTC
ACCATGTGGTTAAAGCGGTGCAATCCGGTCGAAACTTGCGTATAGGCTCACTGGGATTAGACAGTGACAACGAGCTATCT
AATCTTGCCGAGCAGTTTGACCGCATGTTGGATCTGTTGCAGCGACGCAATAGCCAAATTCAAGCTGCCGCCGAGCAACT
TGAGGTCAAGGTTGAGGAGCGTACTCGTAGCCTGCAAGAAAAGACCGAAGAGCTACAGGCCAACGTGGCCCTGTTAAATG
AGACCCGCCAACAGCTGGTGATCAATGAGAAATTGACCGCTTTGGGTGAATTAACGGCAGGTATTGCCCATGAGATCAAC
AATCCGACCGCGGTGATCCTAGGCAATATGGAGTTACTTAAATACGAGCTAGGCGATAGAGCGGTTGATGTCGAAGAAGA
GATAGAACTGGTTATTCAGCAAGTGGGACGGATTAGCACCATTATTCGTAGTTTGTTGCAGTACAGCCGTCCAGGCGAAT
TTAATGCACCACTTGAGATGCATCAGATCACGCCAATTATTGAAGAGATGTTGGTGTTGGTTCGCCACTCTATTCAGAAA
CAGGAGGTGGTGCTCAATCAAGAGCTTAATGCCAGCTATCCTATACAGGTCAATCGCCCACAACTGCTGCAGGTGTTGAT
TAACCTTGTGGTAAATGCGGCCCATGCAATGAATGGTAAGGGACGGATCTGGATCCGCACTTACGATTGGGTGCAGCATG
GCGAGCCTATCGGGGTAAAAATCGAAGTGGAAGATGAAGGTAAAGGGATCCCGGAAGAGGAACTTAACCGCATTTTTGAT
CCGTTTTTCACCACCCGTAAGGACGGTACTGGCCTAGGGTTATCGCTTAGCTACGGCATTATTAAGCGTATTGGTGGCAC
CATTGAAGTGAGTTCGACAGTGGGTAAGGGGAGCTTATTTACCATCGGCTTGTACCATAAGGCTATTGAAGACCAGAGTA
ATGCTCCCTACGAAGGCTTGCTGTTTAGCGGTAAGCACAATGACATGTCGAAACAATAA

Upstream 100 bases:

>100_bases
GGAGTATCACGTAAAACCCTAGATCGTAAGTATAAAGAGTGGTTTGGCGGCGAAGCCGACAAAGAAGAATAATAAAGAGA
TCGCTCTAGGAGGAGTATCG

Downstream 100 bases:

>100_bases
TCATTGATTGGTATACAAGAAATCATACAGAGTGTGGGTAGTGCTGAATAGCTTGCCCATTCGCTGCTCCTAATCTCTTC
TCTATTTCTCTAGATGGCAA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 711

Protein sequence:

>712_residues
MSFFSNMFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKADLTVANSTLITVQDNQEKQL
ELVMESWPFQNDFRQIGNHPTLQRNNLQQVLDKAKKDLNLDFLRLVSVSEAAADPDLRQMLPHIEGLAPFSGLMVLEPSR
LSRIDPELAERAEVTVIKTLRAHEPNKHEEKRGLLSRSLLPVADINGNVAWYLDGGIMLNRDTRIVDHIRDLVYDKGTLP
ERSIGTVTIFLDNIRISTNVPLHFFPQGDDKQGRALGSLVSSEVREKVLNQGLLWVDRAFVFNDWFISAYSPLKDINGKR
IGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGWLVYRGAYSLLQPIERIHHVVKAVQSGRNLRIGSLGLDSDNELS
NLAEQFDRMLDLLQRRNSQIQAAAEQLEVKVEERTRSLQEKTEELQANVALLNETRQQLVINEKLTALGELTAGIAHEIN
NPTAVILGNMELLKYELGDRAVDVEEEIELVIQQVGRISTIIRSLLQYSRPGEFNAPLEMHQITPIIEEMLVLVRHSIQK
QEVVLNQELNASYPIQVNRPQLLQVLINLVVNAAHAMNGKGRIWIRTYDWVQHGEPIGVKIEVEDEGKGIPEEELNRIFD
PFFTTRKDGTGLGLSLSYGIIKRIGGTIEVSSTVGKGSLFTIGLYHKAIEDQSNAPYEGLLFSGKHNDMSKQ

Sequences:

>Translated_712_residues
MSFFSNMFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKADLTVANSTLITVQDNQEKQL
ELVMESWPFQNDFRQIGNHPTLQRNNLQQVLDKAKKDLNLDFLRLVSVSEAAADPDLRQMLPHIEGLAPFSGLMVLEPSR
LSRIDPELAERAEVTVIKTLRAHEPNKHEEKRGLLSRSLLPVADINGNVAWYLDGGIMLNRDTRIVDHIRDLVYDKGTLP
ERSIGTVTIFLDNIRISTNVPLHFFPQGDDKQGRALGSLVSSEVREKVLNQGLLWVDRAFVFNDWFISAYSPLKDINGKR
IGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGWLVYRGAYSLLQPIERIHHVVKAVQSGRNLRIGSLGLDSDNELS
NLAEQFDRMLDLLQRRNSQIQAAAEQLEVKVEERTRSLQEKTEELQANVALLNETRQQLVINEKLTALGELTAGIAHEIN
NPTAVILGNMELLKYELGDRAVDVEEEIELVIQQVGRISTIIRSLLQYSRPGEFNAPLEMHQITPIIEEMLVLVRHSIQK
QEVVLNQELNASYPIQVNRPQLLQVLINLVVNAAHAMNGKGRIWIRTYDWVQHGEPIGVKIEVEDEGKGIPEEELNRIFD
PFFTTRKDGTGLGLSLSYGIIKRIGGTIEVSSTVGKGSLFTIGLYHKAIEDQSNAPYEGLLFSGKHNDMSKQ
>Mature_711_residues
SFFSNMFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKADLTVANSTLITVQDNQEKQLE
LVMESWPFQNDFRQIGNHPTLQRNNLQQVLDKAKKDLNLDFLRLVSVSEAAADPDLRQMLPHIEGLAPFSGLMVLEPSRL
SRIDPELAERAEVTVIKTLRAHEPNKHEEKRGLLSRSLLPVADINGNVAWYLDGGIMLNRDTRIVDHIRDLVYDKGTLPE
RSIGTVTIFLDNIRISTNVPLHFFPQGDDKQGRALGSLVSSEVREKVLNQGLLWVDRAFVFNDWFISAYSPLKDINGKRI
GMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGWLVYRGAYSLLQPIERIHHVVKAVQSGRNLRIGSLGLDSDNELSN
LAEQFDRMLDLLQRRNSQIQAAAEQLEVKVEERTRSLQEKTEELQANVALLNETRQQLVINEKLTALGELTAGIAHEINN
PTAVILGNMELLKYELGDRAVDVEEEIELVIQQVGRISTIIRSLLQYSRPGEFNAPLEMHQITPIIEEMLVLVRHSIQKQ
EVVLNQELNASYPIQVNRPQLLQVLINLVVNAAHAMNGKGRIWIRTYDWVQHGEPIGVKIEVEDEGKGIPEEELNRIFDP
FFTTRKDGTGLGLSLSYGIIKRIGGTIEVSSTVGKGSLFTIGLYHKAIEDQSNAPYEGLLFSGKHNDMSKQ

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=36.9565217391304, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=37.1681415929204, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1790300, Length=216, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI87081816, Length=291, Percent_Identity=28.1786941580756, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1789149, Length=457, Percent_Identity=23.6323851203501, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI48994928, Length=173, Percent_Identity=29.4797687861272, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87082128, Length=219, Percent_Identity=29.6803652968037, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=28.8888888888889, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=28.1746031746032, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=25.5411255411255, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789808, Length=214, Percent_Identity=28.5046728971963, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80558; Mature: 80427

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFSNMFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKA
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHEEHCC
DLTVANSTLITVQDNQEKQLELVMESWPFQNDFRQIGNHPTLQRNNLQQVLDKAKKDLNL
CEEEECCEEEEEECCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCH
DFLRLVSVSEAAADPDLRQMLPHIEGLAPFSGLMVLEPSRLSRIDPELAERAEVTVIKTL
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEECCHHHHCCCHHHHHHHHHHHHHHH
RAHEPNKHEEKRGLLSRSLLPVADINGNVAWYLDGGIMLNRDTRIVDHIRDLVYDKGTLP
HCCCCCCHHHHHHHHHHCCCCEEECCCCEEEEEECCEEECCCHHHHHHHHHHHHCCCCCC
ERSIGTVTIFLDNIRISTNVPLHFFPQGDDKQGRALGSLVSSEVREKVLNQGLLWVDRAF
CCCCCEEEEEEECEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHH
VFNDWFISAYSPLKDINGKRIGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGWLVY
HHCCHHHHHCCCHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGAYSLLQPIERIHHVVKAVQSGRNLRIGSLGLDSDNELSNLAEQFDRMLDLLQRRNSQI
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHH
QAAAEQLEVKVEERTRSLQEKTEELQANVALLNETRQQLVINEKLTALGELTAGIAHEIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NPTAVILGNMELLKYELGDRAVDVEEEIELVIQQVGRISTIIRSLLQYSRPGEFNAPLEM
CCEEEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
HQITPIIEEMLVLVRHSIQKQEVVLNQELNASYPIQVNRPQLLQVLINLVVNAAHAMNGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCC
GRIWIRTYDWVQHGEPIGVKIEVEDEGKGIPEEELNRIFDPFFTTRKDGTGLGLSLSYGI
CEEEEEEEHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEHHHHH
IKRIGGTIEVSSTVGKGSLFTIGLYHKAIEDQSNAPYEGLLFSGKHNDMSKQ
HHHCCCCEEEECCCCCCCEEEEEHHHHHHCCCCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure 
SFFSNMFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKA
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHEEHCC
DLTVANSTLITVQDNQEKQLELVMESWPFQNDFRQIGNHPTLQRNNLQQVLDKAKKDLNL
CEEEECCEEEEEECCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCH
DFLRLVSVSEAAADPDLRQMLPHIEGLAPFSGLMVLEPSRLSRIDPELAERAEVTVIKTL
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEECCHHHHCCCHHHHHHHHHHHHHHH
RAHEPNKHEEKRGLLSRSLLPVADINGNVAWYLDGGIMLNRDTRIVDHIRDLVYDKGTLP
HCCCCCCHHHHHHHHHHCCCCEEECCCCEEEEEECCEEECCCHHHHHHHHHHHHCCCCCC
ERSIGTVTIFLDNIRISTNVPLHFFPQGDDKQGRALGSLVSSEVREKVLNQGLLWVDRAF
CCCCCEEEEEEECEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHH
VFNDWFISAYSPLKDINGKRIGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGWLVY
HHCCHHHHHCCCHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGAYSLLQPIERIHHVVKAVQSGRNLRIGSLGLDSDNELSNLAEQFDRMLDLLQRRNSQI
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHH
QAAAEQLEVKVEERTRSLQEKTEELQANVALLNETRQQLVINEKLTALGELTAGIAHEIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NPTAVILGNMELLKYELGDRAVDVEEEIELVIQQVGRISTIIRSLLQYSRPGEFNAPLEM
CCEEEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
HQITPIIEEMLVLVRHSIQKQEVVLNQELNASYPIQVNRPQLLQVLINLVVNAAHAMNGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCC
GRIWIRTYDWVQHGEPIGVKIEVEDEGKGIPEEELNRIFDPFFTTRKDGTGLGLSLSYGI
CEEEEEEEHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEHHHHH
IKRIGGTIEVSSTVGKGSLFTIGLYHKAIEDQSNAPYEGLLFSGKHNDMSKQ
HHHCCCCEEEECCCCCCCEEEEEHHHHHHCCCCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]