Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 167040635

GI number: 167040635

Start: 2020647

End: 2021597

Strand: Reverse

Name: mraY

Synonym: Teth514_2012

Alternate gene names: 167040635

Gene position: 2021597-2020647 (Counterclockwise)

Preceding gene: 167040636

Following gene: 167040634

Centisome position: 82.27

GC content: 33.02

Gene sequence:

>951_bases
ATGTTACAAAAGATAATTTTGGCTACAGTTGTTGCTTTTGTGCTAAGCTTGGCCTCTGGTCCTCTTTTTATACCTTATCT
TAGAAAATTAAAATTTGGGCAAAAAGTAAGGGAAGATGGGCCTAAAAGCCACATAAAAAAATCTGGAACCCCTACAATGG
GGGGAATAATGTTTATTACAGCCACAGTTATTTCTACTTTAATTTTTTCTCATTGGAATAAATATTTGGCTATTTTGTTA
TTAGGTTTTTTGGGATATGGTTTAATAGGATTTGCAGATGATTTTCTAAAGGTTTATTTTAAAAGGCCTTTAGGTTTAAA
AGCGAGAGAAAAACTTATTGGACAGTTTTTACTTGCGATAATCATTTCATATTTTGCTCAAGAATATGTAGGAACAGAAG
TGATTTTTCCTTTTTTAAAAACTACTATTGACCTTGGCAATTTTTATATTCCTTTTATAGTTTTTGTGATTGTAGGAACA
GTAAACAGCGTAAACTTGACAGATGGGCTTGATGGATTAGCAGCAGGTGTATCTTTTATTGTTATGGCTTTTTTCACTAT
GACAGCTTTATTTTTAAATAATATAACTTATGGAGCGTTCAGTGCCGCTTTGACAGGAGGATTGCTAGGATTTTTGAGGT
ATAACCGTCATCCTGCGGAAATTTTTATGGGAGATACTGGTTCCTTAGCTATTGGAGGAGCTATAGCTACTGCCGCGGTT
TTGACTAAATTGCCTTTGATTTTGCCCTTGATAGGTATTATTTATGTGGCTGAAGCTTTTTCAGTGATTATTCAGGTATT
GTCTTTTAAATTGTTTGGTAAAAGAGTTTTTAAAATGAGTCCTTTACACCATCATTTTGAACTGTCAGGATGGCAAGAAC
AAAATGTAGTCTACGCTTTTTGGATTGTTACTTTAATTGCGATGTTTTTATCTTTTTATAGTTTAAGCTAA

Upstream 100 bases:

>100_bases
AAAGATATTATCAAAGAAGGGGATTCAATTTTAGTAAAAGGTTCAAGAGGTATGAAAATGGAACAAATAGTACAATTTTT
ACAGGAGAGGGTAAAGTAAA

Downstream 100 bases:

>100_bases
GGAGTGCAAATTATGGAACTAAAGGGTAAAAAAGTTCTTGTGGCAGGTTTAGGAGTTAGCGGAATAGCTTTGTGTAAAGT
GTTGGACAGCTTGAAGGCGA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MLQKIILATVVAFVLSLASGPLFIPYLRKLKFGQKVREDGPKSHIKKSGTPTMGGIMFITATVISTLIFSHWNKYLAILL
LGFLGYGLIGFADDFLKVYFKRPLGLKAREKLIGQFLLAIIISYFAQEYVGTEVIFPFLKTTIDLGNFYIPFIVFVIVGT
VNSVNLTDGLDGLAAGVSFIVMAFFTMTALFLNNITYGAFSAALTGGLLGFLRYNRHPAEIFMGDTGSLAIGGAIATAAV
LTKLPLILPLIGIIYVAEAFSVIIQVLSFKLFGKRVFKMSPLHHHFELSGWQEQNVVYAFWIVTLIAMFLSFYSLS

Sequences:

>Translated_316_residues
MLQKIILATVVAFVLSLASGPLFIPYLRKLKFGQKVREDGPKSHIKKSGTPTMGGIMFITATVISTLIFSHWNKYLAILL
LGFLGYGLIGFADDFLKVYFKRPLGLKAREKLIGQFLLAIIISYFAQEYVGTEVIFPFLKTTIDLGNFYIPFIVFVIVGT
VNSVNLTDGLDGLAAGVSFIVMAFFTMTALFLNNITYGAFSAALTGGLLGFLRYNRHPAEIFMGDTGSLAIGGAIATAAV
LTKLPLILPLIGIIYVAEAFSVIIQVLSFKLFGKRVFKMSPLHHHFELSGWQEQNVVYAFWIVTLIAMFLSFYSLS
>Mature_316_residues
MLQKIILATVVAFVLSLASGPLFIPYLRKLKFGQKVREDGPKSHIKKSGTPTMGGIMFITATVISTLIFSHWNKYLAILL
LGFLGYGLIGFADDFLKVYFKRPLGLKAREKLIGQFLLAIIISYFAQEYVGTEVIFPFLKTTIDLGNFYIPFIVFVIVGT
VNSVNLTDGLDGLAAGVSFIVMAFFTMTALFLNNITYGAFSAALTGGLLGFLRYNRHPAEIFMGDTGSLAIGGAIATAAV
LTKLPLILPLIGIIYVAEAFSVIIQVLSFKLFGKRVFKMSPLHHHFELSGWQEQNVVYAFWIVTLIAMFLSFYSLS

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=334, Percent_Identity=43.1137724550898, Blast_Score=243, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_THEP3 (B0K8K4)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001664803.1
- GeneID:   5875416
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_0810
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   TPSE340099:TETH39_0810-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 34830; Mature: 34830

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x19eb4d04)-; HASH(0x1a08b15c)-; HASH(0x1b1a9414)-; HASH(0x1aadbd48)-; HASH(0x19e6b61c)-; HASH(0x1ac11dd8)-; HASH(0x1b18bd5c)-; HASH(0x1a656c1c)-; HASH(0x19826640)-; HASH(0x40405fd0)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQKIILATVVAFVLSLASGPLFIPYLRKLKFGQKVREDGPKSHIKKSGTPTMGGIMFIT
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHH
ATVISTLIFSHWNKYLAILLLGFLGYGLIGFADDFLKVYFKRPLGLKAREKLIGQFLLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IISYFAQEYVGTEVIFPFLKTTIDLGNFYIPFIVFVIVGTVNSVNLTDGLDGLAAGVSFI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
VMAFFTMTALFLNNITYGAFSAALTGGLLGFLRYNRHPAEIFMGDTGSLAIGGAIATAAV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCHHHHHHHHHHH
LTKLPLILPLIGIIYVAEAFSVIIQVLSFKLFGKRVFKMSPLHHHFELSGWQEQNVVYAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHH
WIVTLIAMFLSFYSLS
HHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLQKIILATVVAFVLSLASGPLFIPYLRKLKFGQKVREDGPKSHIKKSGTPTMGGIMFIT
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHH
ATVISTLIFSHWNKYLAILLLGFLGYGLIGFADDFLKVYFKRPLGLKAREKLIGQFLLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IISYFAQEYVGTEVIFPFLKTTIDLGNFYIPFIVFVIVGTVNSVNLTDGLDGLAAGVSFI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
VMAFFTMTALFLNNITYGAFSAALTGGLLGFLRYNRHPAEIFMGDTGSLAIGGAIATAAV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCHHHHHHHHHHH
LTKLPLILPLIGIIYVAEAFSVIIQVLSFKLFGKRVFKMSPLHHHFELSGWQEQNVVYAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHH
WIVTLIAMFLSFYSLS
HHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA