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The map label for this gene is murA2 [H]

Identifier: 167040631

GI number: 167040631

Start: 2015731

End: 2016984

Strand: Reverse

Name: murA2 [H]

Synonym: Teth514_2008

Alternate gene names: 167040631

Gene position: 2016984-2015731 (Counterclockwise)

Preceding gene: 167040632

Following gene: 167040630

Centisome position: 82.08

GC content: 36.52

Gene sequence:

>1254_bases
ATGGGGAAATTTAAAATTAATGGAGGGAACAGGCTGTATGGTGAGTTAAAGGTAAATGGCGCTAAAAATTCTGTTTTACC
CATCCTTGCAGCATCAATTTTAAATGAAGGGATTTCTGTAATACATGATTGTCCTAAATTAAAAGATGTTTATTCAATGA
TAGAAATTTTAGAACATTTAGGTTGTAAGGTAACTTTTAAAGGCAGAGACATTATTGTAGATGCAAGGGATGTAAAAGAT
AGTGAAATACCTGATAGCTTAATGAGAACCATGAGGTCATCTATATTTTTGATGGGGGCTTTAATATCAAGAAACAAAAA
AGCTTTGATGAGTTTTCCAGGAGGTTGTGATATAGGACACAGACCTATAGATTTACACCTTAAGGGTTTGAGAAGATTAG
GAGTTAAAGTGGAAGAATCTTATGGATATATTAAATGTGAAGGTGGGAAGATAAGAGGAAATGAAATTCACTTAGACCTT
CCTAGTGTAGGAGCCACAGAAAATATCATGTTGGCGGGAGTTTTTGCAGAAGGCGTCACCATCATTAGAAATGCAGCAAA
AGAACCGGAAATAGAAGACTTGCAGAATTTTTTAAACTCTATGGGGGCTAAAATATCAGGAGCTGGTACTAACACGATTA
TCATAGAAGGAGTAAAAAGATTGCATGATGCGGAATACACCATAATTTCAGATAGAATTGTTGCGGGTACTTATCTTTGT
GCTGCGGCGATGACACGAGGAGAATTAACAGTAGTAAATGCTTTAAAAGAACATTTAGAACCATTGTTGTCAAAATTGAG
AGAAACGGGATGCGAAATACATGCTGGAAATGATTATATAAAAATTATATGCGATAAGCGCCCCAAAGCAGTAGATATGA
TTGTTACATTGCCATACCCTGGCTTTCCCACAGATTTACAGCCCCAGATGGTTTCGGTTTTATCTGTAGCAGATGGGACA
TCTATTGTTACAGAAACAATATTTGATAATAGATTTAAATACACAGAAGAACTTATACGAATGGGAGCAGATATAAAAGT
GGAGGGAAGAGTAGCGGTAATACGTGGTGTTGAGAAGCTAATGGGTGCAAAAGTAGTAGCAAGAGATTTAAGGGGAGGAG
CTGCTTTGATTATTGCAGGTTTGGGGGCAGAAGGTACTACAATAGTAGATGAAGCAGAACACATTGATAGAGGATATGAA
TCAATCGAAAAGGCTTTAAAAAGTGTGGGAGGGGATATTGTAAGAATAATGTAA

Upstream 100 bases:

>100_bases
TACAAGCTTATAAAAAGCATAACTTAATACCCTATGTAACACCCCATCTTATTTATGCATAGTATATGGTGTAAGCTGTA
TTAAATTTAGGGGTGATAAG

Downstream 100 bases:

>100_bases
AACAGCGTCATGCTGTTTTACATATGCAAAAGAAAAGTACAAGCAGGGGATGGTTTAATGGTTGAAAGTGCTTTTAAGAA
GCGGTTTTTAATATTTATGT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MGKFKINGGNRLYGELKVNGAKNSVLPILAASILNEGISVIHDCPKLKDVYSMIEILEHLGCKVTFKGRDIIVDARDVKD
SEIPDSLMRTMRSSIFLMGALISRNKKALMSFPGGCDIGHRPIDLHLKGLRRLGVKVEESYGYIKCEGGKIRGNEIHLDL
PSVGATENIMLAGVFAEGVTIIRNAAKEPEIEDLQNFLNSMGAKISGAGTNTIIIEGVKRLHDAEYTIISDRIVAGTYLC
AAAMTRGELTVVNALKEHLEPLLSKLRETGCEIHAGNDYIKIICDKRPKAVDMIVTLPYPGFPTDLQPQMVSVLSVADGT
SIVTETIFDNRFKYTEELIRMGADIKVEGRVAVIRGVEKLMGAKVVARDLRGGAALIIAGLGAEGTTIVDEAEHIDRGYE
SIEKALKSVGGDIVRIM

Sequences:

>Translated_417_residues
MGKFKINGGNRLYGELKVNGAKNSVLPILAASILNEGISVIHDCPKLKDVYSMIEILEHLGCKVTFKGRDIIVDARDVKD
SEIPDSLMRTMRSSIFLMGALISRNKKALMSFPGGCDIGHRPIDLHLKGLRRLGVKVEESYGYIKCEGGKIRGNEIHLDL
PSVGATENIMLAGVFAEGVTIIRNAAKEPEIEDLQNFLNSMGAKISGAGTNTIIIEGVKRLHDAEYTIISDRIVAGTYLC
AAAMTRGELTVVNALKEHLEPLLSKLRETGCEIHAGNDYIKIICDKRPKAVDMIVTLPYPGFPTDLQPQMVSVLSVADGT
SIVTETIFDNRFKYTEELIRMGADIKVEGRVAVIRGVEKLMGAKVVARDLRGGAALIIAGLGAEGTTIVDEAEHIDRGYE
SIEKALKSVGGDIVRIM
>Mature_416_residues
GKFKINGGNRLYGELKVNGAKNSVLPILAASILNEGISVIHDCPKLKDVYSMIEILEHLGCKVTFKGRDIIVDARDVKDS
EIPDSLMRTMRSSIFLMGALISRNKKALMSFPGGCDIGHRPIDLHLKGLRRLGVKVEESYGYIKCEGGKIRGNEIHLDLP
SVGATENIMLAGVFAEGVTIIRNAAKEPEIEDLQNFLNSMGAKISGAGTNTIIIEGVKRLHDAEYTIISDRIVAGTYLCA
AAMTRGELTVVNALKEHLEPLLSKLRETGCEIHAGNDYIKIICDKRPKAVDMIVTLPYPGFPTDLQPQMVSVLSVADGTS
IVTETIFDNRFKYTEELIRMGADIKVEGRVAVIRGVEKLMGAKVVARDLRGGAALIIAGLGAEGTTIVDEAEHIDRGYES
IEKALKSVGGDIVRIM

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=48.3253588516746, Blast_Score=387, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45300; Mature: 45168

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKFKINGGNRLYGELKVNGAKNSVLPILAASILNEGISVIHDCPKLKDVYSMIEILEHL
CCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GCKVTFKGRDIIVDARDVKDSEIPDSLMRTMRSSIFLMGALISRNKKALMSFPGGCDIGH
CCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
RPIDLHLKGLRRLGVKVEESYGYIKCEGGKIRGNEIHLDLPSVGATENIMLAGVFAEGVT
CCHHHHHHHHHHCCCEEECCCCEEEECCCEEECCEEEEECCCCCCCCCEEEEEEHHHHHH
IIRNAAKEPEIEDLQNFLNSMGAKISGAGTNTIIIEGVKRLHDAEYTIISDRIVAGTYLC
HHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEHHHHHHCCCCEEEEECHHHHHHHHH
AAAMTRGELTVVNALKEHLEPLLSKLRETGCEIHAGNDYIKIICDKRPKAVDMIVTLPYP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCEEEEEEECCCC
GFPTDLQPQMVSVLSVADGTSIVTETIFDNRFKYTEELIRMGADIKVEGRVAVIRGVEKL
CCCCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHH
MGAKVVARDLRGGAALIIAGLGAEGTTIVDEAEHIDRGYESIEKALKSVGGDIVRIM
HHHHHHHHHCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure 
GKFKINGGNRLYGELKVNGAKNSVLPILAASILNEGISVIHDCPKLKDVYSMIEILEHL
CEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GCKVTFKGRDIIVDARDVKDSEIPDSLMRTMRSSIFLMGALISRNKKALMSFPGGCDIGH
CCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
RPIDLHLKGLRRLGVKVEESYGYIKCEGGKIRGNEIHLDLPSVGATENIMLAGVFAEGVT
CCHHHHHHHHHHCCCEEECCCCEEEECCCEEECCEEEEECCCCCCCCCEEEEEEHHHHHH
IIRNAAKEPEIEDLQNFLNSMGAKISGAGTNTIIIEGVKRLHDAEYTIISDRIVAGTYLC
HHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEHHHHHHCCCCEEEEECHHHHHHHHH
AAAMTRGELTVVNALKEHLEPLLSKLRETGCEIHAGNDYIKIICDKRPKAVDMIVTLPYP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCEEEEEEECCCC
GFPTDLQPQMVSVLSVADGTSIVTETIFDNRFKYTEELIRMGADIKVEGRVAVIRGVEKL
CCCCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHH
MGAKVVARDLRGGAALIIAGLGAEGTTIVDEAEHIDRGYESIEKALKSVGGDIVRIM
HHHHHHHHHCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]