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The map label for this gene is murG

Identifier: 167040632

GI number: 167040632

Start: 2017058

End: 2018152

Strand: Reverse

Name: murG

Synonym: Teth514_2009

Alternate gene names: 167040632

Gene position: 2018152-2017058 (Counterclockwise)

Preceding gene: 167040633

Following gene: 167040631

Centisome position: 82.13

GC content: 30.96

Gene sequence:

>1095_bases
TTGAAATATTTGTTTGCAGGTGGAGGTACTGGAGGACATATTTATCCTGCCATAGCCATTGCTAAGGAAATATTAAAAAA
TGAAAAAAATGCTCAAATTTTATTTGTAGGTACAAAAAAAGGTTTAGAAAATGAGTTAGTACCAAGAGAAGGTTTTGAAT
TAAAGACGATTACTGTGCAAGGATTTAAAAGGAAATTATCATTGGATACGTTAAAAACTATTTATAAAGCAATGGTGGGT
CTTAAGGAAGCAAATAATATTTTAAATGAATTTAAACCAGATGTAGTAATTGGAACAGGGGGATATGTTTGCGGTCCTGT
TTTAATGATGGCGGCTTTAAAAGGGATACCTACTTTGATTCATGAACAAAATGCTTTTCCAGGCCTTACAAATAAGGTAC
TATCACGATTTGTGAAAGTAGTAGCGGTAAGTTTTGAAGAATCAGTTAAATATTTTAAAAATAAAGAAAAAGTTGTGGTA
ACAGGTAATCCAATTAGAAGAGAATTGCTAAAAGTTACTAAAGAGGAAGGTTTAAAAAATTTGGGTTTTTATTCTGATAA
ACCTTTAATAGTATCAGTAGGGGGAAGTAGAGGAGCAGAAAAAATAAATTTTACAATGGTAGAATTTTTAAAGCAAAAGG
ATAAAAACTTGCAAGTTTTAATAATTACAGGAGCTAATCAATATGAAAAAGTGTTGGAAAAAGTTAAAACTGAAACTATA
GACATAGATGAAACAGTTAAAATAATTCCTTATTGTCACAATATGCAGGATGTATATGCTGCCGCAGATATTATAATCTG
TAGGGCTGGGGCTATTACTTTGGCAGAAATTACTGCAAAAGGTGTTGCTTCTATTTTGATTCCTTCTCCTTATGTTGCTA
ATAATCACCAAGAGTATAACGCCCGGGTGTTAGAAAAAGCCGGAGCTTCTTATGTTATTTTAGAAAAGGATTTGACAGCA
GAAAAATTATACAAAAAAATCAAATATCTTTTGGATAATCCTCAAGTACTTTCAAAAATGAGAGATAATGCCCAAAAAAT
TTCTAAAATTGATGCTGCGGAGAAAATATACAAGCTTATAAAAAGCATAACTTAA

Upstream 100 bases:

>100_bases
TATAAGTTATGGAGGTACTTCTACAGTTATTATGATGGCAGGAGTAGGAATACTATTAAATATTTCACGATATGCAAATT
TAGATAGGAGTTGATGATAA

Downstream 100 bases:

>100_bases
TACCCTATGTAACACCCCATCTTATTTATGCATAGTATATGGTGTAAGCTGTATTAAATTTAGGGGTGATAAGATGGGGA
AATTTAAAATTAATGGAGGG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKYLFAGGGTGGHIYPAIAIAKEILKNEKNAQILFVGTKKGLENELVPREGFELKTITVQGFKRKLSLDTLKTIYKAMVG
LKEANNILNEFKPDVVIGTGGYVCGPVLMMAALKGIPTLIHEQNAFPGLTNKVLSRFVKVVAVSFEESVKYFKNKEKVVV
TGNPIRRELLKVTKEEGLKNLGFYSDKPLIVSVGGSRGAEKINFTMVEFLKQKDKNLQVLIITGANQYEKVLEKVKTETI
DIDETVKIIPYCHNMQDVYAAADIIICRAGAITLAEITAKGVASILIPSPYVANNHQEYNARVLEKAGASYVILEKDLTA
EKLYKKIKYLLDNPQVLSKMRDNAQKISKIDAAEKIYKLIKSIT

Sequences:

>Translated_364_residues
MKYLFAGGGTGGHIYPAIAIAKEILKNEKNAQILFVGTKKGLENELVPREGFELKTITVQGFKRKLSLDTLKTIYKAMVG
LKEANNILNEFKPDVVIGTGGYVCGPVLMMAALKGIPTLIHEQNAFPGLTNKVLSRFVKVVAVSFEESVKYFKNKEKVVV
TGNPIRRELLKVTKEEGLKNLGFYSDKPLIVSVGGSRGAEKINFTMVEFLKQKDKNLQVLIITGANQYEKVLEKVKTETI
DIDETVKIIPYCHNMQDVYAAADIIICRAGAITLAEITAKGVASILIPSPYVANNHQEYNARVLEKAGASYVILEKDLTA
EKLYKKIKYLLDNPQVLSKMRDNAQKISKIDAAEKIYKLIKSIT
>Mature_364_residues
MKYLFAGGGTGGHIYPAIAIAKEILKNEKNAQILFVGTKKGLENELVPREGFELKTITVQGFKRKLSLDTLKTIYKAMVG
LKEANNILNEFKPDVVIGTGGYVCGPVLMMAALKGIPTLIHEQNAFPGLTNKVLSRFVKVVAVSFEESVKYFKNKEKVVV
TGNPIRRELLKVTKEEGLKNLGFYSDKPLIVSVGGSRGAEKINFTMVEFLKQKDKNLQVLIITGANQYEKVLEKVKTETI
DIDETVKIIPYCHNMQDVYAAADIIICRAGAITLAEITAKGVASILIPSPYVANNHQEYNARVLEKAGASYVILEKDLTA
EKLYKKIKYLLDNPQVLSKMRDNAQKISKIDAAEKIYKLIKSIT

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=355, Percent_Identity=30.4225352112676, Blast_Score=181, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_THEP3 (B0K8K7)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001664806.1
- ProteinModelPortal:   B0K8K7
- SMR:   B0K8K7
- GeneID:   5874351
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_0813
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   TPSE340099:TETH39_0813-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 40358; Mature: 40358

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLFAGGGTGGHIYPAIAIAKEILKNEKNAQILFVGTKKGLENELVPREGFELKTITVQ
CCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEE
GFKRKLSLDTLKTIYKAMVGLKEANNILNEFKPDVVIGTGGYVCGPVLMMAALKGIPTLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCHHHH
HEQNAFPGLTNKVLSRFVKVVAVSFEESVKYFKNKEKVVVTGNPIRRELLKVTKEEGLKN
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCHHH
LGFYSDKPLIVSVGGSRGAEKINFTMVEFLKQKDKNLQVLIITGANQYEKVLEKVKTETI
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCC
DIDETVKIIPYCHNMQDVYAAADIIICRAGAITLAEITAKGVASILIPSPYVANNHQEYN
CCCCCEEEEECCCCHHHHHHHHHHEEECCCCEEHHHHHHHHHHHHCCCCCCCCCCCCHHH
ARVLEKAGASYVILEKDLTAEKLYKKIKYLLDNPQVLSKMRDNAQKISKIDAAEKIYKLI
HHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSIT
HHCC
>Mature Secondary Structure
MKYLFAGGGTGGHIYPAIAIAKEILKNEKNAQILFVGTKKGLENELVPREGFELKTITVQ
CCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEE
GFKRKLSLDTLKTIYKAMVGLKEANNILNEFKPDVVIGTGGYVCGPVLMMAALKGIPTLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCHHHH
HEQNAFPGLTNKVLSRFVKVVAVSFEESVKYFKNKEKVVVTGNPIRRELLKVTKEEGLKN
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCHHH
LGFYSDKPLIVSVGGSRGAEKINFTMVEFLKQKDKNLQVLIITGANQYEKVLEKVKTETI
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCC
DIDETVKIIPYCHNMQDVYAAADIIICRAGAITLAEITAKGVASILIPSPYVANNHQEYN
CCCCCEEEEECCCCHHHHHHHHHHEEECCCCEEHHHHHHHHHHHHCCCCCCCCCCCCHHH
ARVLEKAGASYVILEKDLTAEKLYKKIKYLLDNPQVLSKMRDNAQKISKIDAAEKIYKLI
HHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSIT
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA