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The map label for this gene is yesM [H]

Identifier: 167040588

GI number: 167040588

Start: 1968980

End: 1970224

Strand: Reverse

Name: yesM [H]

Synonym: Teth514_1959

Alternate gene names: 167040588

Gene position: 1970224-1968980 (Counterclockwise)

Preceding gene: 167040589

Following gene: 167040587

Centisome position: 80.18

GC content: 33.9

Gene sequence:

>1245_bases
ATGGGAGAAGTTAAGTTAAGAGATGTAATTGACGTAAAAAAAGTAGAAGAAATATTACAAAATTTCTCGGATGTTACAGG
ACTTGGTGCCATTATCGCAACACCAGATGGAGAAAGTATTACAAAACCTAGTAATTTTACAGAACATTGTTTACTCGTAA
GAGATACTTTGCATGGAAAAAAAGGGTGTTTTAGATCTGATGCAGAATTAGGTAGGCTTTCTTTACAAAAAGGGGGGGTA
GCTATTTCACTTTGCCATTGTGAGATAATTGACTTGGCAGCTCCATTACTGGTAGATGGGAAATGTTGGGGATATGTATT
ATGTGGACAAGTATTTTTATCTCCTCCTACAGAAGAAATGGTTAAAAGAGCAATAGATCGGGCAAAGAATTTCGGCATAG
CTCCTGAAGTATATCTTGAAAAATTTTTAAAGATAAAAGTAGTGCCCCAAGATTACATTATAGCAGCTGGGAATATGCTC
CAGATTATTGCTAGTTACTTAATAGAACTTGGCCTTAATAAACTTATGCAAGAAAAACTTCTTGAGGAAACTAAACGGAG
GTCCGAATATGAAAATATTATTAAAAGTTTAGAGCTAAAAACTCTTCAGTCTCAAGTAAATCCTCATTTTTTATTCAATA
CCCTCAATACGGCTGCTCGATTAGCCTATTTAGAAAATGCGCCACGAACAGCGGAAATTATCTATTCTCTTGCTAGTCTT
CTTAGGTATTCACTTCGAAATCTAGATCAACTTGTTGCCTTAAAAGAAGAGATATCGTACTTAAAACACTACCTTCATAT
CCAAGAAATAAGATATAAAGACCATATAAAATCGCAAATTGATGTTCCAACTGAAATCGAAAACGTACTTCTTCCGGTCA
TGAGTCTACAACCCATAGTAGAAAATGCTATAATTCACGGTCTGGAAGAAAAAGAAGAAGGGGGAGTAATTAATATAAAA
GCTTATCAAAAGGATGAAACAATATTCATTGAAGTAAAGGACAATGGAGTGGGAATAGATAAGAAAATGCTTGAAGTAAT
TAAGAATGATATCGAAAAAGGTAAAGGACATACAACGGCACTAGGCCTACAAAATGTTGATAGACGAATAAAAATGTACT
TTGGAAAAGAATATGGGTTAGAAATAAGGAGCGAAAAAGGAAATGGCACTTTAGTTGTTTTAAAAATACCGATAATTAAG
AAAGAGGTGGGAAAATATAATGAAATACAAAGCAATGATTTGTGA

Upstream 100 bases:

>100_bases
GTATAATTATTTATCTTAGCAGAAGGGAAGAGAACACTGATGAATTTTGTGGTGTTTGCAATTTAGATAATACCTATTTT
GAGGCGAGAAGGTGAGAAAA

Downstream 100 bases:

>100_bases
TGATGAGCCTTTAGAAAGAGAAGTACTTTCTATGATTGTTGATAAAACAGGTTTGCCAATTGAAGTAATATGCGATGCCA
AAAATGGAAATGATGCAATT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MGEVKLRDVIDVKKVEEILQNFSDVTGLGAIIATPDGESITKPSNFTEHCLLVRDTLHGKKGCFRSDAELGRLSLQKGGV
AISLCHCEIIDLAAPLLVDGKCWGYVLCGQVFLSPPTEEMVKRAIDRAKNFGIAPEVYLEKFLKIKVVPQDYIIAAGNML
QIIASYLIELGLNKLMQEKLLEETKRRSEYENIIKSLELKTLQSQVNPHFLFNTLNTAARLAYLENAPRTAEIIYSLASL
LRYSLRNLDQLVALKEEISYLKHYLHIQEIRYKDHIKSQIDVPTEIENVLLPVMSLQPIVENAIIHGLEEKEEGGVINIK
AYQKDETIFIEVKDNGVGIDKKMLEVIKNDIEKGKGHTTALGLQNVDRRIKMYFGKEYGLEIRSEKGNGTLVVLKIPIIK
KEVGKYNEIQSNDL

Sequences:

>Translated_414_residues
MGEVKLRDVIDVKKVEEILQNFSDVTGLGAIIATPDGESITKPSNFTEHCLLVRDTLHGKKGCFRSDAELGRLSLQKGGV
AISLCHCEIIDLAAPLLVDGKCWGYVLCGQVFLSPPTEEMVKRAIDRAKNFGIAPEVYLEKFLKIKVVPQDYIIAAGNML
QIIASYLIELGLNKLMQEKLLEETKRRSEYENIIKSLELKTLQSQVNPHFLFNTLNTAARLAYLENAPRTAEIIYSLASL
LRYSLRNLDQLVALKEEISYLKHYLHIQEIRYKDHIKSQIDVPTEIENVLLPVMSLQPIVENAIIHGLEEKEEGGVINIK
AYQKDETIFIEVKDNGVGIDKKMLEVIKNDIEKGKGHTTALGLQNVDRRIKMYFGKEYGLEIRSEKGNGTLVVLKIPIIK
KEVGKYNEIQSNDL
>Mature_413_residues
GEVKLRDVIDVKKVEEILQNFSDVTGLGAIIATPDGESITKPSNFTEHCLLVRDTLHGKKGCFRSDAELGRLSLQKGGVA
ISLCHCEIIDLAAPLLVDGKCWGYVLCGQVFLSPPTEEMVKRAIDRAKNFGIAPEVYLEKFLKIKVVPQDYIIAAGNMLQ
IIASYLIELGLNKLMQEKLLEETKRRSEYENIIKSLELKTLQSQVNPHFLFNTLNTAARLAYLENAPRTAEIIYSLASLL
RYSLRNLDQLVALKEEISYLKHYLHIQEIRYKDHIKSQIDVPTEIENVLLPVMSLQPIVENAIIHGLEEKEEGGVINIKA
YQKDETIFIEVKDNGVGIDKKMLEVIKNDIEKGKGHTTALGLQNVDRRIKMYFGKEYGLEIRSEKGNGTLVVLKIPIIKK
EVGKYNEIQSNDL

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=227, Percent_Identity=29.0748898678414, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788723, Length=232, Percent_Identity=33.1896551724138, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46687; Mature: 46556

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEVKLRDVIDVKKVEEILQNFSDVTGLGAIIATPDGESITKPSNFTEHCLLVRDTLHGK
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCC
KGCFRSDAELGRLSLQKGGVAISLCHCEIIDLAAPLLVDGKCWGYVLCGQVFLSPPTEEM
CCCCCCCCHHHHHEEECCCEEEEEEHHHHHHHHCCCEECCCCHHHHHCCHHHCCCCHHHH
VKRAIDRAKNFGIAPEVYLEKFLKIKVVPQDYIIAAGNMLQIIASYLIELGLNKLMQEKL
HHHHHHHHHCCCCCHHHHHHHHHEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
LEETKRRSEYENIIKSLELKTLQSQVNPHFLFNTLNTAARLAYLENAPRTAEIIYSLASL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LRYSLRNLDQLVALKEEISYLKHYLHIQEIRYKDHIKSQIDVPTEIENVLLPVMSLQPIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ENAIIHGLEEKEEGGVINIKAYQKDETIFIEVKDNGVGIDKKMLEVIKNDIEKGKGHTTA
HHHHHHCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEE
LGLQNVDRRIKMYFGKEYGLEIRSEKGNGTLVVLKIPIIKKEVGKYNEIQSNDL
ECHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEECHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
GEVKLRDVIDVKKVEEILQNFSDVTGLGAIIATPDGESITKPSNFTEHCLLVRDTLHGK
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCC
KGCFRSDAELGRLSLQKGGVAISLCHCEIIDLAAPLLVDGKCWGYVLCGQVFLSPPTEEM
CCCCCCCCHHHHHEEECCCEEEEEEHHHHHHHHCCCEECCCCHHHHHCCHHHCCCCHHHH
VKRAIDRAKNFGIAPEVYLEKFLKIKVVPQDYIIAAGNMLQIIASYLIELGLNKLMQEKL
HHHHHHHHHCCCCCHHHHHHHHHEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
LEETKRRSEYENIIKSLELKTLQSQVNPHFLFNTLNTAARLAYLENAPRTAEIIYSLASL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LRYSLRNLDQLVALKEEISYLKHYLHIQEIRYKDHIKSQIDVPTEIENVLLPVMSLQPIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ENAIIHGLEEKEEGGVINIKAYQKDETIFIEVKDNGVGIDKKMLEVIKNDIEKGKGHTTA
HHHHHHCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEE
LGLQNVDRRIKMYFGKEYGLEIRSEKGNGTLVVLKIPIIKKEVGKYNEIQSNDL
ECHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEECHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]