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The map label for this gene is yiaY [H]

Identifier: 167040564

GI number: 167040564

Start: 1945757

End: 1946926

Strand: Reverse

Name: yiaY [H]

Synonym: Teth514_1935

Alternate gene names: 167040564

Gene position: 1946926-1945757 (Counterclockwise)

Preceding gene: 167040565

Following gene: 167040563

Centisome position: 79.23

GC content: 34.87

Gene sequence:

>1170_bases
GTGAAAATATTTAAATTCCATATGCCCCCTATAAATTTAATAGGTGTGGGATGTTTAAAAGATGTGGGAAGGGAGATCAA
AAAATTAGGTTTTAAAAAAGGAATTATTGTTACAGATAAAGTACTTGTCAGAGCTGGGCTTGTGAATAATGTAATTAGTG
TTTTAGAAGAAGAAGGAATAGAATATGTTGTCTTTGATGAAACAAAACCCAACCCTACAATTAAAAATGTAACAAATGGA
CTTAAGCTTTTGATAGAGAATAAGTGTGATTTTATTATTTCGTGCGGCGGAGGATCAGCTCATGACTGCGCAAAAGGGAT
AGGCCTCATTGCTAAAGAGAAGAATTTCATTGATGAGGTAGAGCGTCTAGACAAAGTAAAGTGTGGTGGTTGGAATAGTG
CATTATTACTGCCCCTAGTTGCTATAAATACCACGGCTGGAACAGGTAGTGAAGTTACTAAATTTGCTATAATTACAGAT
GAAGAAAAACGTATTAAAATGCCAATTGTGGATTGGCGCATTACACCTCTAATAGCAGTAAATGATCCTCTCTTGATGAT
AGGTATGCCAAAATCTCTAACAGCTGCAAGTGGCATGGATGCACTAACTCACGCTATTGAAGCTTACATTTCGATTGATG
CAAATCCATTTACAGATGCACTTGCTTTGAAAGCTATTGAAATTATATTCAACTACCTTAAAAGAGCGGTAGAAAATGGA
AATGATATTGAAGCAAGAGAAAAGATGGCATATGCAGAGTTCTTGGCGGGGATTGCTTTTAATAACGCAGGTTTAGGTTA
TGTCCATGCTATGGCTCATCAATTAGGAGGATTTTACGATCTTCCTCATGGTGTATGTAATGCCGTATTATTACCTCATG
TTTTGGAATATAATCTTGAGGCAGTTCAAAATAAACTTATATATATAGCGAAAGCGATGGGTATAGATGTAGATAAATTA
ACAACAAAAGAAATAGGAGGCAAAATTATTGAAAGCATAAACCAGCTCTCTCAAGAGATTGGTATACCATCGAGGTTAAA
AGAACTGGGGGTAAAAGAAGAAGACATTAAAGAGTTATCGCAAAATGCATTAAAAGATGTATGTGGTTTTACAAATCCTA
AAAAGGCAACATTAGAAGATATTATTAATATTTTCAAGTCTGCAATGTAA

Upstream 100 bases:

>100_bases
AATTACAGTTATAAACTAGGAGAGTATTCTTATTTATTGATTGAGGAAGGATTGTATTTTCTATAAACTTTAAAAAAGTT
TTTGATATGAGGTGATAAAT

Downstream 100 bases:

>100_bases
AAACTAGCATAAAATTTTTAGCGGGAATAAGTTAATTAAATTTTACCTTGCTTCTAAATGCCACAACGCATAGAGTTATA
AATAGATTTATAAATAATGA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKIFKFHMPPINLIGVGCLKDVGREIKKLGFKKGIIVTDKVLVRAGLVNNVISVLEEEGIEYVVFDETKPNPTIKNVTNG
LKLLIENKCDFIISCGGGSAHDCAKGIGLIAKEKNFIDEVERLDKVKCGGWNSALLLPLVAINTTAGTGSEVTKFAIITD
EEKRIKMPIVDWRITPLIAVNDPLLMIGMPKSLTAASGMDALTHAIEAYISIDANPFTDALALKAIEIIFNYLKRAVENG
NDIEAREKMAYAEFLAGIAFNNAGLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVLEYNLEAVQNKLIYIAKAMGIDVDKL
TTKEIGGKIIESINQLSQEIGIPSRLKELGVKEEDIKELSQNALKDVCGFTNPKKATLEDIINIFKSAM

Sequences:

>Translated_389_residues
MKIFKFHMPPINLIGVGCLKDVGREIKKLGFKKGIIVTDKVLVRAGLVNNVISVLEEEGIEYVVFDETKPNPTIKNVTNG
LKLLIENKCDFIISCGGGSAHDCAKGIGLIAKEKNFIDEVERLDKVKCGGWNSALLLPLVAINTTAGTGSEVTKFAIITD
EEKRIKMPIVDWRITPLIAVNDPLLMIGMPKSLTAASGMDALTHAIEAYISIDANPFTDALALKAIEIIFNYLKRAVENG
NDIEAREKMAYAEFLAGIAFNNAGLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVLEYNLEAVQNKLIYIAKAMGIDVDKL
TTKEIGGKIIESINQLSQEIGIPSRLKELGVKEEDIKELSQNALKDVCGFTNPKKATLEDIINIFKSAM
>Mature_389_residues
MKIFKFHMPPINLIGVGCLKDVGREIKKLGFKKGIIVTDKVLVRAGLVNNVISVLEEEGIEYVVFDETKPNPTIKNVTNG
LKLLIENKCDFIISCGGGSAHDCAKGIGLIAKEKNFIDEVERLDKVKCGGWNSALLLPLVAINTTAGTGSEVTKFAIITD
EEKRIKMPIVDWRITPLIAVNDPLLMIGMPKSLTAASGMDALTHAIEAYISIDANPFTDALALKAIEIIFNYLKRAVENG
NDIEAREKMAYAEFLAGIAFNNAGLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVLEYNLEAVQNKLIYIAKAMGIDVDKL
TTKEIGGKIIESINQLSQEIGIPSRLKELGVKEEDIKELSQNALKDVCGFTNPKKATLEDIINIFKSAM

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=422, Percent_Identity=27.9620853080569, Blast_Score=156, Evalue=4e-38,
Organism=Escherichia coli, GI48994951, Length=389, Percent_Identity=54.7557840616967, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1789163, Length=373, Percent_Identity=44.7721179624665, Blast_Score=311, Evalue=3e-86,
Organism=Escherichia coli, GI87082107, Length=388, Percent_Identity=35.8247422680412, Blast_Score=250, Evalue=9e-68,
Organism=Escherichia coli, GI1787493, Length=385, Percent_Identity=35.0649350649351, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI1789386, Length=373, Percent_Identity=24.9329758713137, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17537053, Length=412, Percent_Identity=28.1553398058252, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6321181, Length=385, Percent_Identity=49.0909090909091, Blast_Score=363, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24657991, Length=413, Percent_Identity=28.8135593220339, Blast_Score=157, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 42462; Mature: 42462

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIFKFHMPPINLIGVGCLKDVGREIKKLGFKKGIIVTDKVLVRAGLVNNVISVLEEEGI
CCEEEECCCCHHHEEHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCC
EYVVFDETKPNPTIKNVTNGLKLLIENKCDFIISCGGGSAHDCAKGIGLIAKEKNFIDEV
EEEEECCCCCCCCHHHHHHHHHHHEECCCCEEEECCCCCHHHHHHHCCCCCCCHHHHHHH
ERLDKVKCGGWNSALLLPLVAINTTAGTGSEVTKFAIITDEEKRIKMPIVDWRITPLIAV
HHHHCCCCCCCCCHHHHHHHHEECCCCCCCCCEEEEEEECCCCEEECCEECEEECEEEEE
NDPLLMIGMPKSLTAASGMDALTHAIEAYISIDANPFTDALALKAIEIIFNYLKRAVENG
CCCEEEEECCCHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
NDIEAREKMAYAEFLAGIAFNNAGLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVLEYNLE
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
AVQNKLIYIAKAMGIDVDKLTTKEIGGKIIESINQLSQEIGIPSRLKELGVKEEDIKELS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
QNALKDVCGFTNPKKATLEDIINIFKSAM
HHHHHHHHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIFKFHMPPINLIGVGCLKDVGREIKKLGFKKGIIVTDKVLVRAGLVNNVISVLEEEGI
CCEEEECCCCHHHEEHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCC
EYVVFDETKPNPTIKNVTNGLKLLIENKCDFIISCGGGSAHDCAKGIGLIAKEKNFIDEV
EEEEECCCCCCCCHHHHHHHHHHHEECCCCEEEECCCCCHHHHHHHCCCCCCCHHHHHHH
ERLDKVKCGGWNSALLLPLVAINTTAGTGSEVTKFAIITDEEKRIKMPIVDWRITPLIAV
HHHHCCCCCCCCCHHHHHHHHEECCCCCCCCCEEEEEEECCCCEEECCEECEEECEEEEE
NDPLLMIGMPKSLTAASGMDALTHAIEAYISIDANPFTDALALKAIEIIFNYLKRAVENG
CCCEEEEECCCHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
NDIEAREKMAYAEFLAGIAFNNAGLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVLEYNLE
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
AVQNKLIYIAKAMGIDVDKLTTKEIGGKIIESINQLSQEIGIPSRLKELGVKEEDIKELS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
QNALKDVCGFTNPKKATLEDIINIFKSAM
HHHHHHHHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]