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The map label for this gene is ackA [H]

Identifier: 167040565

GI number: 167040565

Start: 1947207

End: 1948421

Strand: Reverse

Name: ackA [H]

Synonym: Teth514_1936

Alternate gene names: 167040565

Gene position: 1948421-1947207 (Counterclockwise)

Preceding gene: 167040566

Following gene: 167040564

Centisome position: 79.29

GC content: 34.4

Gene sequence:

>1215_bases
ATGAAGATATTGGTCCTTAACTGTGGAAGTTCATCTGTAAAATACCAACTAATTGAAACAGATAATGAGTTGGCATTAGC
AAAAGGAATTATTGATAGAATAGGTTTGAATGACTCAACGGTAAAATATAGTTCATTAAATGGAGAATGTGCAACTACTG
AGCAGATCCAAAATCATGAAGAAGCGATTCAAAAAGTTTTGCAACTTATTACAGATCAATCAATAGGAGTATTAGGCAGC
TTGGATGAAATTGATGCTATTGGCCATCGCATTGCTCATGGAGGAGAATACTTTACAAAACCCACCCTTATTGATGAAAC
ATCGAAAAGATTACTTAAAAAGTGCATAGATTTAGCCCCATTGCATAACCCTGCTAATATAAGGGGGATAGAAGCCTGTG
AACACAAGATACCTGGCAAACCCAATATAGGAGTTTTTGATACCGCATTTCATCAAACTATCCCAGAATATGCATATTTA
TACCCTTTACCGTATGAACTGTATGAAAAACACAAGATAAGAAGATATGGATTTCATGGAACTTCGCATAAGTATGTAGC
ATTAAAAGCTGCAGAATACTTGAATAAAAGAGTAGAAGAGTTGAATTTGATAACCTGTCATTTAGGAAATGGAGCAAGTA
TCTGTGCTATAAAAAAAGGGAAGTCTTCAGATACGAGTATGGGTTTTACACCTTTAGAAGGTTTAATGATGGGAACACGG
AGCGGCTCAATTGATCCTGCAATTGTTATATATCTTATGCAAAAGGGAAATATGAGTGTTGAAAAGGTGAATGAGATTTT
AAATAAAAAGTCTGGGTTGTTGGGGATTTCAGGGGTAAGCAATGATCTAAGAGATATATTGAAGGCAGCAAACAACGGAA
ATCAACGAGCTCAAATTGCTATAGAAATGTTTTGCTATAGAGTAAGAAAATATATTGGTGGATACATGACAACTCTAGAT
GGAGTGAATGCTATTGTCTTTACGGGAGGAATTGGAGAAAATAGCCCAGAAGTAAGAGAAAGAACTATAATTGGGTTAGA
ATGGATTGGTATAGAATATGATAAAGAAAAGAATTATAGCCATAAAAAATGCGATCAAATTGTAGAAATAACAAAACCAA
ATTCGAAAATTAAGGTGCTTGTAATTCCTACAAATGAAGAACTCATGATTGCTAAGGAAACTGCGGAAGTAATGAGCTTT
TTTGATAACAAATAA

Upstream 100 bases:

>100_bases
GGAAAATATTATTTTCGTTTCAGCAATAACGGGTGAAGGGATGAAGAAACTGGAAGAAACAATTAACAAAATATTGAAGG
AATGAATGGAGGAAGCTTTG

Downstream 100 bases:

>100_bases
TCTTTGTTCTTCCTGTATATATAGTGGATTTAGTGGATTGTAAAACCAAAAAAACAACACAAGAAATTAAAAATACAAAA
AGTCAAAGACCAAAAGTAAA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKILVLNCGSSSVKYQLIETDNELALAKGIIDRIGLNDSTVKYSSLNGECATTEQIQNHEEAIQKVLQLITDQSIGVLGS
LDEIDAIGHRIAHGGEYFTKPTLIDETSKRLLKKCIDLAPLHNPANIRGIEACEHKIPGKPNIGVFDTAFHQTIPEYAYL
YPLPYELYEKHKIRRYGFHGTSHKYVALKAAEYLNKRVEELNLITCHLGNGASICAIKKGKSSDTSMGFTPLEGLMMGTR
SGSIDPAIVIYLMQKGNMSVEKVNEILNKKSGLLGISGVSNDLRDILKAANNGNQRAQIAIEMFCYRVRKYIGGYMTTLD
GVNAIVFTGGIGENSPEVRERTIIGLEWIGIEYDKEKNYSHKKCDQIVEITKPNSKIKVLVIPTNEELMIAKETAEVMSF
FDNK

Sequences:

>Translated_404_residues
MKILVLNCGSSSVKYQLIETDNELALAKGIIDRIGLNDSTVKYSSLNGECATTEQIQNHEEAIQKVLQLITDQSIGVLGS
LDEIDAIGHRIAHGGEYFTKPTLIDETSKRLLKKCIDLAPLHNPANIRGIEACEHKIPGKPNIGVFDTAFHQTIPEYAYL
YPLPYELYEKHKIRRYGFHGTSHKYVALKAAEYLNKRVEELNLITCHLGNGASICAIKKGKSSDTSMGFTPLEGLMMGTR
SGSIDPAIVIYLMQKGNMSVEKVNEILNKKSGLLGISGVSNDLRDILKAANNGNQRAQIAIEMFCYRVRKYIGGYMTTLD
GVNAIVFTGGIGENSPEVRERTIIGLEWIGIEYDKEKNYSHKKCDQIVEITKPNSKIKVLVIPTNEELMIAKETAEVMSF
FDNK
>Mature_404_residues
MKILVLNCGSSSVKYQLIETDNELALAKGIIDRIGLNDSTVKYSSLNGECATTEQIQNHEEAIQKVLQLITDQSIGVLGS
LDEIDAIGHRIAHGGEYFTKPTLIDETSKRLLKKCIDLAPLHNPANIRGIEACEHKIPGKPNIGVFDTAFHQTIPEYAYL
YPLPYELYEKHKIRRYGFHGTSHKYVALKAAEYLNKRVEELNLITCHLGNGASICAIKKGKSSDTSMGFTPLEGLMMGTR
SGSIDPAIVIYLMQKGNMSVEKVNEILNKKSGLLGISGVSNDLRDILKAANNGNQRAQIAIEMFCYRVRKYIGGYMTTLD
GVNAIVFTGGIGENSPEVRERTIIGLEWIGIEYDKEKNYSHKKCDQIVEITKPNSKIKVLVIPTNEELMIAKETAEVMSF
FDNK

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=401, Percent_Identity=46.1346633416459, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI145693184, Length=389, Percent_Identity=43.1876606683805, Blast_Score=330, Evalue=7e-92,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 44874; Mature: 44874

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVLNCGSSSVKYQLIETDNELALAKGIIDRIGLNDSTVKYSSLNGECATTEQIQNHE
CEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHH
EAIQKVLQLITDQSIGVLGSLDEIDAIGHRIAHGGEYFTKPTLIDETSKRLLKKCIDLAP
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCC
LHNPANIRGIEACEHKIPGKPNIGVFDTAFHQTIPEYAYLYPLPYELYEKHKIRRYGFHG
CCCCCCCCHHHHHHHCCCCCCCCCEEHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCCCC
TSHKYVALKAAEYLNKRVEELNLITCHLGNGASICAIKKGKSSDTSMGFTPLEGLMMGTR
CCCCEEEEHHHHHHHHHHHHCEEEEEECCCCCEEEEEECCCCCCCCCCCCCHHHHEEECC
SGSIDPAIVIYLMQKGNMSVEKVNEILNKKSGLLGISGVSNDLRDILKAANNGNQRAQIA
CCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCHHHHH
IEMFCYRVRKYIGGYMTTLDGVNAIVFTGGIGENSPEVRERTIIGLEWIGIEYDKEKNYS
HHHHHHHHHHHHCCHHHHHCCCCEEEEECCCCCCCCHHHHHEEEEEEEEEEEECCCCCCC
HKKCDQIVEITKPNSKIKVLVIPTNEELMIAKETAEVMSFFDNK
HHHHHHHHEECCCCCEEEEEEEECCCCEEEEHHHHHHHHHHCCC
>Mature Secondary Structure
MKILVLNCGSSSVKYQLIETDNELALAKGIIDRIGLNDSTVKYSSLNGECATTEQIQNHE
CEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHH
EAIQKVLQLITDQSIGVLGSLDEIDAIGHRIAHGGEYFTKPTLIDETSKRLLKKCIDLAP
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCC
LHNPANIRGIEACEHKIPGKPNIGVFDTAFHQTIPEYAYLYPLPYELYEKHKIRRYGFHG
CCCCCCCCHHHHHHHCCCCCCCCCEEHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCCCC
TSHKYVALKAAEYLNKRVEELNLITCHLGNGASICAIKKGKSSDTSMGFTPLEGLMMGTR
CCCCEEEEHHHHHHHHHHHHCEEEEEECCCCCEEEEEECCCCCCCCCCCCCHHHHEEECC
SGSIDPAIVIYLMQKGNMSVEKVNEILNKKSGLLGISGVSNDLRDILKAANNGNQRAQIA
CCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCHHHHH
IEMFCYRVRKYIGGYMTTLDGVNAIVFTGGIGENSPEVRERTIIGLEWIGIEYDKEKNYS
HHHHHHHHHHHHCCHHHHHCCCCEEEEECCCCCCCCHHHHHEEEEEEEEEEEECCCCCCC
HKKCDQIVEITKPNSKIKVLVIPTNEELMIAKETAEVMSFFDNK
HHHHHHHHEECCCCCEEEEEEEECCCCEEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA