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The map label for this gene is aroQ

Identifier: 167040159

GI number: 167040159

Start: 1549236

End: 1549682

Strand: Direct

Name: aroQ

Synonym: Teth514_1521

Alternate gene names: 167040159

Gene position: 1549236-1549682 (Clockwise)

Preceding gene: 167040158

Following gene: 167040160

Centisome position: 63.05

GC content: 33.78

Gene sequence:

>447_bases
ATGAAAAGAGTTTTGATAATTCATGGCCCTAATGTAAATCTGACAGGTAAAAGAGAAAAAGAGGTATATGGAGATATAAA
TTACGAAGAAATAAATAATCTGATAAAAAGAGAGGCTGCAAAATTAGATATAGCTGTCAAGATTCAGCAATCTAATAGTG
AAGGAGAAATAATTAATCTTATTCATTCTGCAGAAAACAATTTCGATGCTATAATTATAAATCCTGCAGCTTACACTCAT
TACAGTTTAGCTATTATGGATGCTATTGCAGCTGTGTCAGTTCCAGTAATAGAAGTTCATATTTCAAATATTTTTGGAAG
GGAGGATTACAGAAAGACCTCTGTTACTGCATCTAAATGCAAAGGTGTGATAACGGGGTTTGGACCTTATAGTTATGTCC
TTGCCCTCAATGCAGTTAAGCTTTTAGAGGATTCAATTGGGGGGTAA

Upstream 100 bases:

>100_bases
GGCCAATGGGACTTGAGGAGCTTACCACCTACAAATATGTAATTTTAGGTAGTGGACAAATAAGGAAATAAGGTGTATTA
TAGTAAAGTGAGGTGAGATT

Downstream 100 bases:

>100_bases
ATTCATGAATAAAAGATTACAAAATTTGAGAAATTTGATGAAGAAAAGAGATATAGAGGCTTTTGTGATTTACAAATTTG
TCAATGTTACATATATTACT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MKRVLIIHGPNVNLTGKREKEVYGDINYEEINNLIKREAAKLDIAVKIQQSNSEGEIINLIHSAENNFDAIIINPAAYTH
YSLAIMDAIAAVSVPVIEVHISNIFGREDYRKTSVTASKCKGVITGFGPYSYVLALNAVKLLEDSIGG

Sequences:

>Translated_148_residues
MKRVLIIHGPNVNLTGKREKEVYGDINYEEINNLIKREAAKLDIAVKIQQSNSEGEIINLIHSAENNFDAIIINPAAYTH
YSLAIMDAIAAVSVPVIEVHISNIFGREDYRKTSVTASKCKGVITGFGPYSYVLALNAVKLLEDSIGG
>Mature_148_residues
MKRVLIIHGPNVNLTGKREKEVYGDINYEEINNLIKREAAKLDIAVKIQQSNSEGEIINLIHSAENNFDAIIINPAAYTH
YSLAIMDAIAAVSVPVIEVHISNIFGREDYRKTSVTASKCKGVITGFGPYSYVLALNAVKLLEDSIGG

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_THEP3 (B0K9C6)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001665075.1
- ProteinModelPortal:   B0K9C6
- SMR:   B0K9C6
- GeneID:   5875379
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_1084
- HOGENOM:   HBG284657
- OMA:   VHMSNIH
- ProtClustDB:   PRK05395
- BioCyc:   TPSE340099:TETH39_1084-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16230; Mature: 16230

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 23-23 ACT_SITE 100-100 BINDING 74-74 BINDING 80-80 BINDING 87-87 BINDING 111-111

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVLIIHGPNVNLTGKREKEVYGDINYEEINNLIKREAAKLDIAVKIQQSNSEGEIINL
CCEEEEEECCCCCCCCCCCHHEECCCCHHHHHHHHHHHHHCEEEEEEEECCCCCCCEEEE
IHSAENNFDAIIINPAAYTHYSLAIMDAIAAVSVPVIEVHISNIFGREDYRKTSVTASKC
EECCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCEEEEEEECHHCCCCCHHHHCCCHHHC
KGVITGFGPYSYVLALNAVKLLEDSIGG
CEEEECCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRVLIIHGPNVNLTGKREKEVYGDINYEEINNLIKREAAKLDIAVKIQQSNSEGEIINL
CCEEEEEECCCCCCCCCCCHHEECCCCHHHHHHHHHHHHHCEEEEEEEECCCCCCCEEEE
IHSAENNFDAIIINPAAYTHYSLAIMDAIAAVSVPVIEVHISNIFGREDYRKTSVTASKC
EECCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCEEEEEEECHHCCCCCHHHHCCCHHHC
KGVITGFGPYSYVLALNAVKLLEDSIGG
CEEEECCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA