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The map label for this gene is fur [H]

Identifier: 167040131

GI number: 167040131

Start: 1525579

End: 1526019

Strand: Direct

Name: fur [H]

Synonym: Teth514_1493

Alternate gene names: 167040131

Gene position: 1525579-1526019 (Clockwise)

Preceding gene: 167040130

Following gene: 167040132

Centisome position: 62.08

GC content: 31.07

Gene sequence:

>441_bases
GTGAATGAAATTGAAAAATTTAAAGAAAAATTAAAAGATAAGGGTTATAAGTTGACAACTCAAAGGCGTGTGATATTGGA
CGTTATTATGGAGAATAGGGATAAACATCTTTCCTCTGAGGAAATATATGACCTTGTAAGGCTAAAATATCCTGAAATAG
GGCTTGCTACAGTTTACAGGACCCTTCAGTTATTTGAGGAATTAGGTATTGTCTATAAATTAAATTTTGACGATGGTCGA
AATCGATACGAGCTATATCATAATGAAAACCATCAGCATCATCATTTGATTTGTCTAAAATGCGGAGCAGTTATAGAAAT
GGAAGGAGACCTTTTGGAGAATTTAGAAGAGGCAATAGAAAAAACTAAAGATTTTGAAATAATAGACCATAATGTAAAAT
TTTTTGGTTATTGTAGCAAATGTAGGAAGAGTTATAATTAA

Upstream 100 bases:

>100_bases
TATAAAATTTGATATTTGCTAAAAAATCAAAAAAATATTTGACAATTGAAAATGAATATCATAAACTAATATTAGTTGAT
ATTATTTGGCGGTGATTTAG

Downstream 100 bases:

>100_bases
ATTTGGGTTTTTGTTTGAGAAATAATTTACATTAACAGGGTTGAAGTATTTTTTTAAATAAAGTATAATTTATATTAACT
GGTGTAAGGTACGGGTAAGT

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MNEIEKFKEKLKDKGYKLTTQRRVILDVIMENRDKHLSSEEIYDLVRLKYPEIGLATVYRTLQLFEELGIVYKLNFDDGR
NRYELYHNENHQHHHLICLKCGAVIEMEGDLLENLEEAIEKTKDFEIIDHNVKFFGYCSKCRKSYN

Sequences:

>Translated_146_residues
MNEIEKFKEKLKDKGYKLTTQRRVILDVIMENRDKHLSSEEIYDLVRLKYPEIGLATVYRTLQLFEELGIVYKLNFDDGR
NRYELYHNENHQHHHLICLKCGAVIEMEGDLLENLEEAIEKTKDFEIIDHNVKFFGYCSKCRKSYN
>Mature_146_residues
MNEIEKFKEKLKDKGYKLTTQRRVILDVIMENRDKHLSSEEIYDLVRLKYPEIGLATVYRTLQLFEELGIVYKLNFDDGR
NRYELYHNENHQHHHLICLKCGAVIEMEGDLLENLEEAIEKTKDFEIIDHNVKFFGYCSKCRKSYN

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=135, Percent_Identity=39.2592592592593, Blast_Score=98, Evalue=2e-22,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17505; Mature: 17505

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEIEKFKEKLKDKGYKLTTQRRVILDVIMENRDKHLSSEEIYDLVRLKYPEIGLATVYR
CCHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHH
TLQLFEELGIVYKLNFDDGRNRYELYHNENHQHHHLICLKCGAVIEMEGDLLENLEEAIE
HHHHHHHCCEEEEEECCCCCCEEEEECCCCCCCEEEEEEECCEEEEECCHHHHHHHHHHH
KTKDFEIIDHNVKFFGYCSKCRKSYN
HCCCCEEEECCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNEIEKFKEKLKDKGYKLTTQRRVILDVIMENRDKHLSSEEIYDLVRLKYPEIGLATVYR
CCHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHH
TLQLFEELGIVYKLNFDDGRNRYELYHNENHQHHHLICLKCGAVIEMEGDLLENLEEAIE
HHHHHHHCCEEEEEECCCCCCEEEEECCCCCCCEEEEEEECCEEEEECCHHHHHHHHHHH
KTKDFEIIDHNVKFFGYCSKCRKSYN
HCCCCEEEECCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]