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The map label for this gene is ruvC [H]

Identifier: 167040092

GI number: 167040092

Start: 1486533

End: 1487081

Strand: Direct

Name: ruvC [H]

Synonym: Teth514_1452

Alternate gene names: 167040092

Gene position: 1486533-1487081 (Clockwise)

Preceding gene: 167040091

Following gene: 167040093

Centisome position: 60.5

GC content: 36.07

Gene sequence:

>549_bases
TTGTTTATAAAGGTCATTGATGTTAAAATAAATAAAAGGAGAGGGGATATAATGAGGGTATTAGGGATAGATCCTGGAAT
TGCCATAATGGGCTATGGTATAATAGATTACAAATCCAATAAGTTTACTGTTATAGACTACGGTGCAGTTACTACAAAAG
CTGGTATTGATAAGGCTTTGCGCCTACACGATATATATAATGGAATTATATCACTTATAAAATCATACAGCCCTGATGTA
GTGGCTATAGAAGAGCTTTTTTACAATAAAAACGCAAAGACTGTCATAACTATTGGAGAATCCAGAGGAGTTTCTATTTT
AGCCGCTGTCAATTCGGGAATAAAGGTTTTTGAATATACTCCTTTGCAAGTTAAACAAGCAGTGGTAGGGTACGGAAGAG
CAGATAAACATCAAGTTCAACAAATGGTGAAGGCTTTATTAGATCTTGAGGAAATTCCTAGACCTGACGATGTAGCTGAT
GCCTTGGCAGTTGCTATATGCCATTGTCACAGTAACAATATGATTGAAAAGCTGGGGTATTCAAGATGA

Upstream 100 bases:

>100_bases
AGTGATGGAAAATATAATTACAAAAGACAAAGATGAAGCATACCAAATATTAGCAAATTTAAGCTCTTAAGTTCTCCTAT
GTTTTTAGGAGAACTTTTTC

Downstream 100 bases:

>100_bases
TTGAGTATGTTAGAGGGATAATTGAAGATATTGGACAAGATTACGTAGTGATTGACTTTATGGGTATAGGTATAAAGGTT
TTTGTTCCCTTTTCTACTTT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MFIKVIDVKINKRRGDIMRVLGIDPGIAIMGYGIIDYKSNKFTVIDYGAVTTKAGIDKALRLHDIYNGIISLIKSYSPDV
VAIEELFYNKNAKTVITIGESRGVSILAAVNSGIKVFEYTPLQVKQAVVGYGRADKHQVQQMVKALLDLEEIPRPDDVAD
ALAVAICHCHSNNMIEKLGYSR

Sequences:

>Translated_182_residues
MFIKVIDVKINKRRGDIMRVLGIDPGIAIMGYGIIDYKSNKFTVIDYGAVTTKAGIDKALRLHDIYNGIISLIKSYSPDV
VAIEELFYNKNAKTVITIGESRGVSILAAVNSGIKVFEYTPLQVKQAVVGYGRADKHQVQQMVKALLDLEEIPRPDDVAD
ALAVAICHCHSNNMIEKLGYSR
>Mature_182_residues
MFIKVIDVKINKRRGDIMRVLGIDPGIAIMGYGIIDYKSNKFTVIDYGAVTTKAGIDKALRLHDIYNGIISLIKSYSPDV
VAIEELFYNKNAKTVITIGESRGVSILAAVNSGIKVFEYTPLQVKQAVVGYGRADKHQVQQMVKALLDLEEIPRPDDVAD
ALAVAICHCHSNNMIEKLGYSR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=163, Percent_Identity=45.398773006135, Blast_Score=124, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 20098; Mature: 20098

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIKVIDVKINKRRGDIMRVLGIDPGIAIMGYGIIDYKSNKFTVIDYGAVTTKAGIDKAL
CEEEEEEEEECCCCCCEEEEEECCCCCEEEEEEEEEECCCEEEEEECCCEECHHHHHHHH
RLHDIYNGIISLIKSYSPDVVAIEELFYNKNAKTVITIGESRGVSILAAVNSGIKVFEYT
HHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCCEEEEECCCCCEEEEEEECCCCEEEEEC
PLQVKQAVVGYGRADKHQVQQMVKALLDLEEIPRPDDVADALAVAICHCHSNNMIEKLGY
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCC
SR
CC
>Mature Secondary Structure
MFIKVIDVKINKRRGDIMRVLGIDPGIAIMGYGIIDYKSNKFTVIDYGAVTTKAGIDKAL
CEEEEEEEEECCCCCCEEEEEECCCCCEEEEEEEEEECCCEEEEEECCCEECHHHHHHHH
RLHDIYNGIISLIKSYSPDVVAIEELFYNKNAKTVITIGESRGVSILAAVNSGIKVFEYT
HHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCCEEEEECCCCCEEEEEEECCCCEEEEEC
PLQVKQAVVGYGRADKHQVQQMVKALLDLEEIPRPDDVADALAVAICHCHSNNMIEKLGY
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCC
SR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]