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The map label for this gene is ruvA

Identifier: 167040093

GI number: 167040093

Start: 1487078

End: 1487641

Strand: Direct

Name: ruvA

Synonym: Teth514_1453

Alternate gene names: 167040093

Gene position: 1487078-1487641 (Clockwise)

Preceding gene: 167040092

Following gene: 167040094

Centisome position: 60.52

GC content: 32.8

Gene sequence:

>564_bases
ATGATTGAGTATGTTAGAGGGATAATTGAAGATATTGGACAAGATTACGTAGTGATTGACTTTATGGGTATAGGTATAAA
GGTTTTTGTTCCCTTTTCTACTTTAAAAGTTTTACCTTCTAAAGGAAATATAACCAAGCTTTATACATATTTACAGGTAA
GAGAAGATGGTTTTCAAATTTTTGGCTTTAAAACAAAAGAAGAGCTAGATTTGTTTGAAAAATTATTGTCTGTTAGTGGT
GTAGGGCCTAAAGGAGCTTTGTCTATTTTGTCCGTGGTTTCTATTGACAATTTTGTAAAAGCAGTTAACGCAGGCGATTA
TAAAGCTCTTACAGTAGCTCCGGGAATAGGCAAAAAGACTGCTGAGAGAATTATTTTGGAATTAAAAGATAAGCTTCCAA
AAGAAATAGTTTTTGAAGGTGATAATAATTTTTCAAATGAGGCTTTAGAAGCTTTATTAGCGTTGGGTTACACCAAGAGT
GAAGCTATTTATGCTTTGGCAGATATCACCTGTGATAGCGTAGAAGATGCTGTAAAGCAAGCTTTGAAAAAATTAATGAA
ATAG

Upstream 100 bases:

>100_bases
TTGAGGAAATTCCTAGACCTGACGATGTAGCTGATGCCTTGGCAGTTGCTATATGCCATTGTCACAGTAACAATATGATT
GAAAAGCTGGGGTATTCAAG

Downstream 100 bases:

>100_bases
GGTGAATTAAATGGAGGAAAGAATACTAACTCAAAATTTTACACAGGAAGATGCCTCCGAATACAGTTTGCGTCCTAGGT
GGCTTTCTGAGTATATAGGT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MIEYVRGIIEDIGQDYVVIDFMGIGIKVFVPFSTLKVLPSKGNITKLYTYLQVREDGFQIFGFKTKEELDLFEKLLSVSG
VGPKGALSILSVVSIDNFVKAVNAGDYKALTVAPGIGKKTAERIILELKDKLPKEIVFEGDNNFSNEALEALLALGYTKS
EAIYALADITCDSVEDAVKQALKKLMK

Sequences:

>Translated_187_residues
MIEYVRGIIEDIGQDYVVIDFMGIGIKVFVPFSTLKVLPSKGNITKLYTYLQVREDGFQIFGFKTKEELDLFEKLLSVSG
VGPKGALSILSVVSIDNFVKAVNAGDYKALTVAPGIGKKTAERIILELKDKLPKEIVFEGDNNFSNEALEALLALGYTKS
EAIYALADITCDSVEDAVKQALKKLMK
>Mature_187_residues
MIEYVRGIIEDIGQDYVVIDFMGIGIKVFVPFSTLKVLPSKGNITKLYTYLQVREDGFQIFGFKTKEELDLFEKLLSVSG
VGPKGALSILSVVSIDNFVKAVNAGDYKALTVAPGIGKKTAERIILELKDKLPKEIVFEGDNNFSNEALEALLALGYTKS
EAIYALADITCDSVEDAVKQALKKLMK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=36.9458128078818, Blast_Score=117, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_THEP3 (B0K955)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001665004.1
- ProteinModelPortal:   B0K955
- SMR:   B0K955
- GeneID:   5873361
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_1013
- HOGENOM:   HBG635309
- OMA:   LFGFAQK
- ProtClustDB:   PRK00116
- BioCyc:   TPSE340099:TETH39_1013-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 20548; Mature: 20548

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEYVRGIIEDIGQDYVVIDFMGIGIKVFVPFSTLKVLPSKGNITKLYTYLQVREDGFQI
CHHHHHHHHHHCCCCEEEEEEECCCEEEEECHHHHEEECCCCCHHHHHHEEEEECCCEEE
FGFKTKEELDLFEKLLSVSGVGPKGALSILSVVSIDNFVKAVNAGDYKALTVAPGIGKKT
EECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHH
AERIILELKDKLPKEIVFEGDNNFSNEALEALLALGYTKSEAIYALADITCDSVEDAVKQ
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHEEHHHHCCHHHHHHHHHH
ALKKLMK
HHHHHCC
>Mature Secondary Structure
MIEYVRGIIEDIGQDYVVIDFMGIGIKVFVPFSTLKVLPSKGNITKLYTYLQVREDGFQI
CHHHHHHHHHHCCCCEEEEEEECCCEEEEECHHHHEEECCCCCHHHHHHEEEEECCCEEE
FGFKTKEELDLFEKLLSVSGVGPKGALSILSVVSIDNFVKAVNAGDYKALTVAPGIGKKT
EECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHH
AERIILELKDKLPKEIVFEGDNNFSNEALEALLALGYTKSEAIYALADITCDSVEDAVKQ
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHEEHHHHCCHHHHHHHHHH
ALKKLMK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA