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The map label for this gene is xylR [H]

Identifier: 167040072

GI number: 167040072

Start: 1466309

End: 1467454

Strand: Direct

Name: xylR [H]

Synonym: Teth514_1432

Alternate gene names: 167040072

Gene position: 1466309-1467454 (Clockwise)

Preceding gene: 167040069

Following gene: 167040073

Centisome position: 59.67

GC content: 33.25

Gene sequence:

>1146_bases
TTGAAAGACTATACTAAAGGCACTTCAGGGTTAATTAAAAATATCAATAAAGCCAATGTTTTAGATGTTATTAAAAAGAT
GCAACCCATATCGAGAATAGAGGTTTCTAAAGTTTTAAAAATGAGCAAATCTACTATTTCTGCCATTGTAGATGAGTTGA
TTGAAGAAGGTTTGGTAATAGAAAATGGTTACGGAGAAAAAGGTACAGTAGGGAGAAAGCCTATACAGCTTTCTTTTAAT
CCTGATGCTAGATTTGTTATAGGGATAAGCGTTGAATCTACAAATTCGATAGGAATTCTGACTAATTTAGAGGGGAAAAT
TTTAAAAAAGATAAAATGGGAAACTGGCATTAAAGAACAGGCTTTTAATGGAATTGTGAAAGGGATAAAAGAACTTGCTG
AGGAAGATAAAAATATAATAGGAATTGGTATTGGTCTTCCAGGAATCACAGATATACAAAAAGGAATTGTTGATGCACCA
GGATTGAAATGGAGTAATTTTGATTTAAAGAAAAGGTTGAGTGAAATTTTTAATTATAACATCTACGTGGACAACAGTGT
AAATTATGCTGCACTGGGCGAGAGATGGATTGGTTGTTGCCGTGAAATAGAGAATTTTGTGCTTATAAACATAGGAAATG
GTATAGGCTCGGGAATATATGTAAATGGTACTTTATTACGAGGCAATAGTTACGCTGCAGGGGAAGTAGGGTACATGGCC
ATAGGAGAGGATGCTTTTGAAAGAGTTTATTCTTACGAGGATTATGGTTATTTTGAAAGAAAGGCTTCTTTGTCTGCTTT
AGTTGAATCAGTTTCTAAAAGTTTGCCTTATGTAAAAACTATGGAGGGTGTAGTAAAAGAATATAAAAAACAAAATCCTG
CTTGTGTACAAGCTGTATCTCAATTTATTAAAAATTTAAGCATGGGTATTGCCAATATTGTAAGTATCTTAAACCCAGAA
GTGATAATAATTGGAGGAGACATTTTAAACTATGAAATTGATATACGCCAGGAGCTAAAGGAGAAAGTGAAAAGGATTGT
GCCTTTTGATTTTGACATTAAAGTAGCTCAACTTGGTGAAGATGCTTCTGCTATTGGGGCGGTAGCCGATGTGCTTTTAA
ATACAAATAATTTAATTTTACTATAA

Upstream 100 bases:

>100_bases
TTTCAAATTATTATGGTATAATAATTACAAGAAAATGTTCGGATATCGAACTAATTTTTTAGATAATTAGTTCAGATAAT
GAACTAATGGAGGCGAGATA

Downstream 100 bases:

>100_bases
GGAGGCCATAAGATGAAAGTAATTATAACTGTAAATTATGAGGAAATGAGTAAAAAGGCAGCAGAAATTGTGAAAAAGCA
AATCAAAGAAAAACCTAATA

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKDYTKGTSGLIKNINKANVLDVIKKMQPISRIEVSKVLKMSKSTISAIVDELIEEGLVIENGYGEKGTVGRKPIQLSFN
PDARFVIGISVESTNSIGILTNLEGKILKKIKWETGIKEQAFNGIVKGIKELAEEDKNIIGIGIGLPGITDIQKGIVDAP
GLKWSNFDLKKRLSEIFNYNIYVDNSVNYAALGERWIGCCREIENFVLINIGNGIGSGIYVNGTLLRGNSYAAGEVGYMA
IGEDAFERVYSYEDYGYFERKASLSALVESVSKSLPYVKTMEGVVKEYKKQNPACVQAVSQFIKNLSMGIANIVSILNPE
VIIIGGDILNYEIDIRQELKEKVKRIVPFDFDIKVAQLGEDASAIGAVADVLLNTNNLILL

Sequences:

>Translated_381_residues
MKDYTKGTSGLIKNINKANVLDVIKKMQPISRIEVSKVLKMSKSTISAIVDELIEEGLVIENGYGEKGTVGRKPIQLSFN
PDARFVIGISVESTNSIGILTNLEGKILKKIKWETGIKEQAFNGIVKGIKELAEEDKNIIGIGIGLPGITDIQKGIVDAP
GLKWSNFDLKKRLSEIFNYNIYVDNSVNYAALGERWIGCCREIENFVLINIGNGIGSGIYVNGTLLRGNSYAAGEVGYMA
IGEDAFERVYSYEDYGYFERKASLSALVESVSKSLPYVKTMEGVVKEYKKQNPACVQAVSQFIKNLSMGIANIVSILNPE
VIIIGGDILNYEIDIRQELKEKVKRIVPFDFDIKVAQLGEDASAIGAVADVLLNTNNLILL
>Mature_381_residues
MKDYTKGTSGLIKNINKANVLDVIKKMQPISRIEVSKVLKMSKSTISAIVDELIEEGLVIENGYGEKGTVGRKPIQLSFN
PDARFVIGISVESTNSIGILTNLEGKILKKIKWETGIKEQAFNGIVKGIKELAEEDKNIIGIGIGLPGITDIQKGIVDAP
GLKWSNFDLKKRLSEIFNYNIYVDNSVNYAALGERWIGCCREIENFVLINIGNGIGSGIYVNGTLLRGNSYAAGEVGYMA
IGEDAFERVYSYEDYGYFERKASLSALVESVSKSLPYVKTMEGVVKEYKKQNPACVQAVSQFIKNLSMGIANIVSILNPE
VIIIGGDILNYEIDIRQELKEKVKRIVPFDFDIKVAQLGEDASAIGAVADVLLNTNNLILL

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=271, Percent_Identity=29.520295202952, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4885285, Length=275, Percent_Identity=29.0909090909091, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI298566325, Length=271, Percent_Identity=29.520295202952, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI190014632, Length=271, Percent_Identity=29.520295202952, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1786891, Length=338, Percent_Identity=24.5562130177515, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1787878, Length=340, Percent_Identity=22.3529411764706, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787363, Length=255, Percent_Identity=23.1372549019608, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082127, Length=370, Percent_Identity=22.7027027027027, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081733, Length=252, Percent_Identity=23.8095238095238, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 41844; Mature: 41844

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDYTKGTSGLIKNINKANVLDVIKKMQPISRIEVSKVLKMSKSTISAIVDELIEEGLVI
CCCCCCCHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
ENGYGEKGTVGRKPIQLSFNPDARFVIGISVESTNSIGILTNLEGKILKKIKWETGIKEQ
ECCCCCCCCCCCCCEEEEECCCCEEEEEEEEECCCCEEEEECCCHHHHHHHHHHCCCHHH
AFNGIVKGIKELAEEDKNIIGIGIGLPGITDIQKGIVDAPGLKWSNFDLKKRLSEIFNYN
HHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCE
IYVDNSVNYAALGERWIGCCREIENFVLINIGNGIGSGIYVNGTLLRGNSYAAGEVGYMA
EEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCEEE
IGEDAFERVYSYEDYGYFERKASLSALVESVSKSLPYVKTMEGVVKEYKKQNPACVQAVS
ECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHH
QFIKNLSMGIANIVSILNPEVIIIGGDILNYEIDIRQELKEKVKRIVPFDFDIKVAQLGE
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEHHHHHHHHHHHHHCCCCCCEEHHHCCC
DASAIGAVADVLLNTNNLILL
CHHHHHHHHHHHCCCCCEEEC
>Mature Secondary Structure
MKDYTKGTSGLIKNINKANVLDVIKKMQPISRIEVSKVLKMSKSTISAIVDELIEEGLVI
CCCCCCCHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
ENGYGEKGTVGRKPIQLSFNPDARFVIGISVESTNSIGILTNLEGKILKKIKWETGIKEQ
ECCCCCCCCCCCCCEEEEECCCCEEEEEEEEECCCCEEEEECCCHHHHHHHHHHCCCHHH
AFNGIVKGIKELAEEDKNIIGIGIGLPGITDIQKGIVDAPGLKWSNFDLKKRLSEIFNYN
HHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCE
IYVDNSVNYAALGERWIGCCREIENFVLINIGNGIGSGIYVNGTLLRGNSYAAGEVGYMA
EEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCEEE
IGEDAFERVYSYEDYGYFERKASLSALVESVSKSLPYVKTMEGVVKEYKKQNPACVQAVS
ECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHH
QFIKNLSMGIANIVSILNPEVIIIGGDILNYEIDIRQELKEKVKRIVPFDFDIKVAQLGE
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEHHHHHHHHHHHHHCCCCCCEEHHHCCC
DASAIGAVADVLLNTNNLILL
CHHHHHHHHHHHCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8920183 [H]