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The map label for this gene is licH [H]

Identifier: 167038934

GI number: 167038934

Start: 281032

End: 282342

Strand: Direct

Name: licH [H]

Synonym: Teth514_0266

Alternate gene names: 167038934

Gene position: 281032-282342 (Clockwise)

Preceding gene: 167038933

Following gene: 167038935

Centisome position: 11.44

GC content: 35.55

Gene sequence:

>1311_bases
ATGTCTAAAAAAGATTTGAAAATTGCTGTAATTGGAGGGGGTTCTAGTTATACCCCCGAACTTATTGAGGGCTTTATCAA
GAGGTATAATGAACTACCAGTTAAAGACTTATATTTAGTAGATATAGAAGAAGGCCAAGAAAAACTTGAGATTGTTGGCG
GTCTTGCAAAAAGAATGGTAGAAAAAGCTGGTGTAGGTATAAACATTCATTTGACTTTGGACAGGCGAAAAGCCATAAAA
GATGCAGATTTTGTTGTTACCCAGTTTAGAGTAGGGCTGATAGATGCAAGAATTAGAGATGAAAAAATTCCTCTAAAGTA
TGATGTTATAGGGCAAGAAACAACTGGACCCGGTGGTTTTGCAAAAGCACAGAGAACAATACCTGTTATTTTAGACATAT
GTAAAGACGTAGAGGAACTTGCTCCAAATGCATGGCTTATTAATTTTACAAATCCTTCAGGAGTGATAACAGAAACGATT
TTAAAGCATACAAATGTAAAAGCGATCGGATTATGTAATGTACCTATAGGTATGGTATACGGTGTTGCAGAAGTACTTGG
TGTTGATCCAAAAAGAGTGTATATAGATTTTACAGGGCTTAATCATTTAGTATGGGGTACTCATATTTACTTAGATGGCG
AAGATATAACCGAAAAACTAATAGACAGTTTCGCAGGTGGTAAATCTTTATCAATGAAAAATATACCTGAGTTGCCATGG
GAACCTGAATTTATAAAATCTCTTGGTATGTATCCTTGTCCATACCACAGATACTATTATTTAACAGATAAAATGCTTGA
AGGACAGAAAAAAGAAGCTGCTACAGTAGGCACAAGAGGAGAAGTCGTTAAAAAGGTAGAGCAAGAATTATTTGAATTAT
ATAAAGACCCAAATTTGAATATAAAACCGCCGCAATTAGAAAAAAGGGGAGGAGCTCATTATTCTGATGCTGCTTGCTCC
CTGATAAGTTCAATATATAATGACAAAAAAGACATACATGTGGTCAATGTGAGAAACAATGGTACAATCGCAGATTTGCC
AGATGATGTGGTGATAGAAACAAATGCAATAATAGATAGAAATGGGGCTCATCCGATAAATATTGGACATGTGCCAGCGA
AAATAAGGGGTTTAATGCAAGCAGTAAAAGCCTATGAAGAACTTACTATAGAAGCAGGGGTAAAGGGGAACTATTATACA
GCTTTACAGGCGTTGACAATTCATCCATTAGTACCTTCTGCGACTGTTGCTAAAAAAATTCTTGATGATATACTTGAGCA
AAATAAAGAGTATTTGCCACAGTATAAATAG

Upstream 100 bases:

>100_bases
GCAGAAGACCATCTTATGAATGCAATTCTTGCAAAAGAATTAATAACGGAAATGGTTGACTTGTATAAAGTTATTTATCA
AACAAAGGGGGCAACTTTTA

Downstream 100 bases:

>100_bases
AAATATTGCTGATTTTACAAAGTAATTTTTTCCGTTAAATTACTTTTTACTTTTTAAATAATATTTTGAATTATCTTGCG
CAAGGAGGAAAATAATTATG

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSKKDLKIAVIGGGSSYTPELIEGFIKRYNELPVKDLYLVDIEEGQEKLEIVGGLAKRMVEKAGVGINIHLTLDRRKAIK
DADFVVTQFRVGLIDARIRDEKIPLKYDVIGQETTGPGGFAKAQRTIPVILDICKDVEELAPNAWLINFTNPSGVITETI
LKHTNVKAIGLCNVPIGMVYGVAEVLGVDPKRVYIDFTGLNHLVWGTHIYLDGEDITEKLIDSFAGGKSLSMKNIPELPW
EPEFIKSLGMYPCPYHRYYYLTDKMLEGQKKEAATVGTRGEVVKKVEQELFELYKDPNLNIKPPQLEKRGGAHYSDAACS
LISSIYNDKKDIHVVNVRNNGTIADLPDDVVIETNAIIDRNGAHPINIGHVPAKIRGLMQAVKAYEELTIEAGVKGNYYT
ALQALTIHPLVPSATVAKKILDDILEQNKEYLPQYK

Sequences:

>Translated_436_residues
MSKKDLKIAVIGGGSSYTPELIEGFIKRYNELPVKDLYLVDIEEGQEKLEIVGGLAKRMVEKAGVGINIHLTLDRRKAIK
DADFVVTQFRVGLIDARIRDEKIPLKYDVIGQETTGPGGFAKAQRTIPVILDICKDVEELAPNAWLINFTNPSGVITETI
LKHTNVKAIGLCNVPIGMVYGVAEVLGVDPKRVYIDFTGLNHLVWGTHIYLDGEDITEKLIDSFAGGKSLSMKNIPELPW
EPEFIKSLGMYPCPYHRYYYLTDKMLEGQKKEAATVGTRGEVVKKVEQELFELYKDPNLNIKPPQLEKRGGAHYSDAACS
LISSIYNDKKDIHVVNVRNNGTIADLPDDVVIETNAIIDRNGAHPINIGHVPAKIRGLMQAVKAYEELTIEAGVKGNYYT
ALQALTIHPLVPSATVAKKILDDILEQNKEYLPQYK
>Mature_435_residues
SKKDLKIAVIGGGSSYTPELIEGFIKRYNELPVKDLYLVDIEEGQEKLEIVGGLAKRMVEKAGVGINIHLTLDRRKAIKD
ADFVVTQFRVGLIDARIRDEKIPLKYDVIGQETTGPGGFAKAQRTIPVILDICKDVEELAPNAWLINFTNPSGVITETIL
KHTNVKAIGLCNVPIGMVYGVAEVLGVDPKRVYIDFTGLNHLVWGTHIYLDGEDITEKLIDSFAGGKSLSMKNIPELPWE
PEFIKSLGMYPCPYHRYYYLTDKMLEGQKKEAATVGTRGEVVKKVEQELFELYKDPNLNIKPPQLEKRGGAHYSDAACSL
ISSIYNDKKDIHVVNVRNNGTIADLPDDVVIETNAIIDRNGAHPINIGHVPAKIRGLMQAVKAYEELTIEAGVKGNYYTA
LQALTIHPLVPSATVAKKILDDILEQNKEYLPQYK

Specific function: Hydrolyzes phospho-beta-glucosides (Probable) [H]

COG id: COG1486

COG function: function code G; Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1788029, Length=441, Percent_Identity=48.0725623582766, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1790560, Length=463, Percent_Identity=24.1900647948164, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019802
- InterPro:   IPR001088
- InterPro:   IPR022616
- InterPro:   IPR015955
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02056 Glyco_hydro_4; PF11975 Glyco_hydro_4C [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 48466; Mature: 48334

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS01324 GLYCOSYL_HYDROL_F4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKDLKIAVIGGGSSYTPELIEGFIKRYNELPVKDLYLVDIEEGQEKLEIVGGLAKRMV
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
EKAGVGINIHLTLDRRKAIKDADFVVTQFRVGLIDARIRDEKIPLKYDVIGQETTGPGGF
HHHCCCEEEEEEECHHHHCCCHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCCCCCCCH
AKAQRTIPVILDICKDVEELAPNAWLINFTNPSGVITETILKHTNVKAIGLCNVPIGMVY
HHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCHHHHH
GVAEVLGVDPKRVYIDFTGLNHLVWGTHIYLDGEDITEKLIDSFAGGKSLSMKNIPELPW
HHHHHHCCCCCEEEEEEECCCEEEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCC
EPEFIKSLGMYPCPYHRYYYLTDKMLEGQKKEAATVGTRGEVVKKVEQELFELYKDPNLN
CHHHHHHCCCCCCCCCEEEEEEHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
IKPPQLEKRGGAHYSDAACSLISSIYNDKKDIHVVNVRNNGTIADLPDDVVIETNAIIDR
CCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCEEEEECEEEEC
NGAHPINIGHVPAKIRGLMQAVKAYEELTIEAGVKGNYYTALQALTIHPLVPSATVAKKI
CCCCCEECCCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHEEEEEEECCCCCCHHHHHHH
LDDILEQNKEYLPQYK
HHHHHHCCHHHCCCCC
>Mature Secondary Structure 
SKKDLKIAVIGGGSSYTPELIEGFIKRYNELPVKDLYLVDIEEGQEKLEIVGGLAKRMV
CCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
EKAGVGINIHLTLDRRKAIKDADFVVTQFRVGLIDARIRDEKIPLKYDVIGQETTGPGGF
HHHCCCEEEEEEECHHHHCCCHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCCCCCCCH
AKAQRTIPVILDICKDVEELAPNAWLINFTNPSGVITETILKHTNVKAIGLCNVPIGMVY
HHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCHHHHH
GVAEVLGVDPKRVYIDFTGLNHLVWGTHIYLDGEDITEKLIDSFAGGKSLSMKNIPELPW
HHHHHHCCCCCEEEEEEECCCEEEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCC
EPEFIKSLGMYPCPYHRYYYLTDKMLEGQKKEAATVGTRGEVVKKVEQELFELYKDPNLN
CHHHHHHCCCCCCCCCEEEEEEHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
IKPPQLEKRGGAHYSDAACSLISSIYNDKKDIHVVNVRNNGTIADLPDDVVIETNAIIDR
CCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCEEEEECEEEEC
NGAHPINIGHVPAKIRGLMQAVKAYEELTIEAGVKGNYYTALQALTIHPLVPSATVAKKI
CCCCCEECCCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHEEEEEEECCCCCCHHHHHHH
LDDILEQNKEYLPQYK
HHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8990303; 9384377; 8969509 [H]