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The map label for this gene is gmuD [H]

Identifier: 167038935

GI number: 167038935

Start: 282440

End: 283834

Strand: Direct

Name: gmuD [H]

Synonym: Teth514_0267

Alternate gene names: 167038935

Gene position: 282440-283834 (Clockwise)

Preceding gene: 167038934

Following gene: 167038936

Centisome position: 11.49

GC content: 33.84

Gene sequence:

>1395_bases
ATGGCTAAAGAATACAAATTTCCTGAAGGATTCTGGTGGGGGTCTGCAACGTCAGCAGTACAAATAGAGGGAGCTGCAAA
TGAAGATGGAAAGGGAATGAATGTATGGGATTATTGGTACAAAAACGAGCCAAATCGCTTTTTCGATAGAGTAGGCCCTC
AAGTAACATCTGATTTTTACCACAGATATAAAGACGATATAAAACTGATGAAAGAACTTGGACATAACTCTTTTAGATTT
TCTATTTCATGGTCGCGGCTGATACCTGGTGGTGTTGGTGAAGTCAATAAAAAAGCCGTAGAGTTTTATAACAGTGTCAT
TGATGAGCTTATAAAAAATGATATAGAACCGTTTGTTACGCTATTTCACTTTGACATGCCTATAGAAATGCAAAACATGG
GAGGTTTTGAGAATAGAAAAGTAGTAGAATATTTTGCTGAATATGCCAAAACATGCTTTGAGTTGTTTGGAGATAGAGTC
AAAAGATGGATTACATTTAATGAACCAATAGTTCCTGTATTAGGTGGATATTTATATAATTTCCATTATCCAGATATAGT
AGATTTTAAAAGAGCAGTACAATTCGCTTATGGCACAGTGCTGGCAAGTGCGAGAGCAATAGAGGAATTTAAAAAATTAC
AAATAGAAAGGGCTAAAATAGGTATTGTTTTAAACTTAAGTCCTGTATATCCCAGGAGTAATCATCCGGCTGATTTAAAA
GCCGCAGAGATTGCAGATTTGTTCTATAACAGAAGTTTTTTGGACCCAACTGTCAAAGGAGAGTATCCTAAAGAACTTGT
TGAACTTCTAAAAACTTACAATCATCTACCAGAGTATTCGGATAGCGACTTAGAATTAATTAAAAATAACACTGTGGAAT
ATTTAGGAGTAAATTATTATCAGCCAATTAGAGTTAAAGCTAAAGAAAATATGCCAAATCCATATGGAGTATTTACACCT
AATTGGTTTTATGATGAGTATATTATGCCAGGCAGAAGAATGAATCCTTATAGAGGATGGGAGATATACGAAAGGGGAAT
ATATGACATAATGATAAATTTAAGAGATAATTATGGCAATATAGGGTCTTTTATTTCGGAAAATGGAATGGGAGTTGAAG
GAGAAGAGCGTTTTATAAAAGATGGAATTATCCAAGATGATTACAGGATAGAGTTTATAAAAGAACATTTGAAGTGGCTC
CATAAAGCAATTGAAGAGGGATGCAATGTAAAAGGATATCATTTATGGACTTTTATGGACAACTGGTCCTTCTTAAATGC
ATATAAAAACCGTTACGGTCTTGTATCTGTCGATCTAAAAACACAGAAAAGAACTATAAAGAAAAGTGGATATTGGTATA
AAGAATTATCCGAAAACAATGGATTTGTTGATTAA

Upstream 100 bases:

>100_bases
TAGAAATATTGCTGATTTTACAAAGTAATTTTTTCCGTTAAATTACTTTTTACTTTTTAAATAATATTTTGAATTATCTT
GCGCAAGGAGGAAAATAATT

Downstream 100 bases:

>100_bases
TCATAACCGGTTTTTTCGCCGGTTATTTTTTTATCTTCAATTTTGTCAAAGAAAACGAATGACAAAACTGATTTTCTTTG
AATTGCATAAATGCATATGG

Product: beta-glucosidase

Products: NA

Alternate protein names: Aryl-phospho-beta-D-glucosidase BglD; Glucomannan utilization protein D [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MAKEYKFPEGFWWGSATSAVQIEGAANEDGKGMNVWDYWYKNEPNRFFDRVGPQVTSDFYHRYKDDIKLMKELGHNSFRF
SISWSRLIPGGVGEVNKKAVEFYNSVIDELIKNDIEPFVTLFHFDMPIEMQNMGGFENRKVVEYFAEYAKTCFELFGDRV
KRWITFNEPIVPVLGGYLYNFHYPDIVDFKRAVQFAYGTVLASARAIEEFKKLQIERAKIGIVLNLSPVYPRSNHPADLK
AAEIADLFYNRSFLDPTVKGEYPKELVELLKTYNHLPEYSDSDLELIKNNTVEYLGVNYYQPIRVKAKENMPNPYGVFTP
NWFYDEYIMPGRRMNPYRGWEIYERGIYDIMINLRDNYGNIGSFISENGMGVEGEERFIKDGIIQDDYRIEFIKEHLKWL
HKAIEEGCNVKGYHLWTFMDNWSFLNAYKNRYGLVSVDLKTQKRTIKKSGYWYKELSENNGFVD

Sequences:

>Translated_464_residues
MAKEYKFPEGFWWGSATSAVQIEGAANEDGKGMNVWDYWYKNEPNRFFDRVGPQVTSDFYHRYKDDIKLMKELGHNSFRF
SISWSRLIPGGVGEVNKKAVEFYNSVIDELIKNDIEPFVTLFHFDMPIEMQNMGGFENRKVVEYFAEYAKTCFELFGDRV
KRWITFNEPIVPVLGGYLYNFHYPDIVDFKRAVQFAYGTVLASARAIEEFKKLQIERAKIGIVLNLSPVYPRSNHPADLK
AAEIADLFYNRSFLDPTVKGEYPKELVELLKTYNHLPEYSDSDLELIKNNTVEYLGVNYYQPIRVKAKENMPNPYGVFTP
NWFYDEYIMPGRRMNPYRGWEIYERGIYDIMINLRDNYGNIGSFISENGMGVEGEERFIKDGIIQDDYRIEFIKEHLKWL
HKAIEEGCNVKGYHLWTFMDNWSFLNAYKNRYGLVSVDLKTQKRTIKKSGYWYKELSENNGFVD
>Mature_463_residues
AKEYKFPEGFWWGSATSAVQIEGAANEDGKGMNVWDYWYKNEPNRFFDRVGPQVTSDFYHRYKDDIKLMKELGHNSFRFS
ISWSRLIPGGVGEVNKKAVEFYNSVIDELIKNDIEPFVTLFHFDMPIEMQNMGGFENRKVVEYFAEYAKTCFELFGDRVK
RWITFNEPIVPVLGGYLYNFHYPDIVDFKRAVQFAYGTVLASARAIEEFKKLQIERAKIGIVLNLSPVYPRSNHPADLKA
AEIADLFYNRSFLDPTVKGEYPKELVELLKTYNHLPEYSDSDLELIKNNTVEYLGVNYYQPIRVKAKENMPNPYGVFTPN
WFYDEYIMPGRRMNPYRGWEIYERGIYDIMINLRDNYGNIGSFISENGMGVEGEERFIKDGIIQDDYRIEFIKEHLKWLH
KAIEEGCNVKGYHLWTFMDNWSFLNAYKNRYGLVSVDLKTQKRTIKKSGYWYKELSENNGFVD

Specific function: Phospho-beta-D-glucosidase that seems to be involved in the degradation of glucomannan. Is also capable of hydrolyzing aryl-phospho-beta-D-glucosides, although very weakly, and plays only a minor role, if any, in the degradation of these substrates in viv

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI13273313, Length=482, Percent_Identity=30.7053941908714, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI110681710, Length=481, Percent_Identity=31.6008316008316, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI32481206, Length=480, Percent_Identity=31.25, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI28376633, Length=480, Percent_Identity=27.7083333333333, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI24497614, Length=481, Percent_Identity=28.2744282744283, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI190360571, Length=97, Percent_Identity=42.2680412371134, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI2367174, Length=497, Percent_Identity=31.7907444668008, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI1789070, Length=482, Percent_Identity=34.8547717842324, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI2367270, Length=488, Percent_Identity=32.5819672131148, Blast_Score=221, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI17539390, Length=472, Percent_Identity=34.5338983050847, Blast_Score=248, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17552856, Length=479, Percent_Identity=33.1941544885177, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI21356577, Length=488, Percent_Identity=29.5081967213115, Blast_Score=229, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54612; Mature: 54480

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEYKFPEGFWWGSATSAVQIEGAANEDGKGMNVWDYWYKNEPNRFFDRVGPQVTSDFY
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEHHHHCCCCHHHHHHCCHHHHHHHH
HRYKDDIKLMKELGHNSFRFSISWSRLIPGGVGEVNKKAVEFYNSVIDELIKNDIEPFVT
HHHHHHHHHHHHCCCCCEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
LFHFDMPIEMQNMGGFENRKVVEYFAEYAKTCFELFGDRVKRWITFNEPIVPVLGGYLYN
HHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHC
FHYPDIVDFKRAVQFAYGTVLASARAIEEFKKLQIERAKIGIVLNLSPVYPRSNHPADLK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCH
AAEIADLFYNRSFLDPTVKGEYPKELVELLKTYNHLPEYSDSDLELIKNNTVEYLGVNYY
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCEEEEECCCC
QPIRVKAKENMPNPYGVFTPNWFYDEYIMPGRRMNPYRGWEIYERGIYDIMINLRDNYGN
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCEEEEEEEECCCCCC
IGSFISENGMGVEGEERFIKDGIIQDDYRIEFIKEHLKWLHKAIEEGCNVKGYHLWTFMD
HHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
NWSFLNAYKNRYGLVSVDLKTQKRTIKKSGYWYKELSENNGFVD
CCHHHHHHHCCCCEEEEECHHHHHHHHHCCCCHHHHCCCCCCCC
>Mature Secondary Structure 
AKEYKFPEGFWWGSATSAVQIEGAANEDGKGMNVWDYWYKNEPNRFFDRVGPQVTSDFY
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEHHHHCCCCHHHHHHCCHHHHHHHH
HRYKDDIKLMKELGHNSFRFSISWSRLIPGGVGEVNKKAVEFYNSVIDELIKNDIEPFVT
HHHHHHHHHHHHCCCCCEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
LFHFDMPIEMQNMGGFENRKVVEYFAEYAKTCFELFGDRVKRWITFNEPIVPVLGGYLYN
HHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHC
FHYPDIVDFKRAVQFAYGTVLASARAIEEFKKLQIERAKIGIVLNLSPVYPRSNHPADLK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCH
AAEIADLFYNRSFLDPTVKGEYPKELVELLKTYNHLPEYSDSDLELIKNNTVEYLGVNYY
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCEEEEECCCC
QPIRVKAKENMPNPYGVFTPNWFYDEYIMPGRRMNPYRGWEIYERGIYDIMINLRDNYGN
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCEEEEEEEECCCCCC
IGSFISENGMGVEGEERFIKDGIIQDDYRIEFIKEHLKWLHKAIEEGCNVKGYHLWTFMD
HHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
NWSFLNAYKNRYGLVSVDLKTQKRTIKKSGYWYKELSENNGFVD
CCHHHHHHHCCCCEEEEECHHHHHHHHHCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]