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The map label for this gene is aspC [H]

Identifier: 167038905

GI number: 167038905

Start: 248334

End: 249500

Strand: Direct

Name: aspC [H]

Synonym: Teth514_0236

Alternate gene names: 167038905

Gene position: 248334-249500 (Clockwise)

Preceding gene: 167038904

Following gene: 167038906

Centisome position: 10.11

GC content: 38.13

Gene sequence:

>1167_bases
ATGAACTTTGAAGACAAGGTGGCAAAAAGAGCAAAATCTATAGAAATATCTACCATAAGATATTTCTTTAACATGGCGCG
AGAGGTGCCGGGAGCAATATCCCTTGCTATTGGAGAGCCGGATTTTGTAACGCCAGCGCATATAAGAGAAGCAGCGAAAA
AAGCCCTCGATGAAGGTAAAACAGGGTACACTGTAAATCCTGGACTTATTGAATTGAGGCAAGAAATTTCGAATTATCTT
AATAGAAGGTATAACCTTTCTTACAATCCGGAAACAGAAATTTTAGTTACAATTGGGGCTACTGAAGCTATATACGTTGC
TTTAAATACTTTGGTAGAAGAAGGAGACGAAGTATTAATTCCAGAACCTTCATTTGTGGCATACCATCCTTGTACAATTC
TTGCAGGTGCTAAATCCGTTTTTGTCCCAACATATGAAGAGGATGATTTTGTATTAAGGGCAGATGTTTTAGAGAAGTAC
ATTACGGACAGATCAAAAGTCTTAATTTTACCCTATCCTAATAATCCAACTGGGGCAGTAATGCCAAAAGAGGCGATGGA
AAAGATAGCTGAAGTGGTCAAAAAGTATGACCTCATTGTAGTTACTGATGAAATTTATTCTGAGCTAGTATACAGTGGTT
TTGAACATGTAAGTTTTGCATCTTTGCCAGACATGTGGGAAAGGACGGTTACTATAAACGGTTTTTCTAAATCCTATGCG
ATGACAGGTTGGCGTCTCGGATATATAGCGGCACCAGAATATTTTATAAAACATATGACAAAAATACACCAATACGGCGT
AACAGCAGCAGCAACGATGTGTCAGTATGCGGGTATAGAGGCTATAAAAAATGGGGACGGAGATATTTTAATGATGAGAG
AAGAGTACGACAAAAGAAGAAAGTATTTGCTTCAAAGTGTGAGAGAAATGGGACTCGATTGTTTTGAGCCAAAGGGTGCT
TTTTACATATTCCCTTCAATAAAAAAGACAGGCCTTACCTCAATGGAATTTGCTAAGAGACTCCTTTACGAAGCAAAAGT
TGCAGTTGTGCCGGGAAATGCCTTTGGAGAAAATGGTGAAGGATATGTTCGCATGGCTTATGCAACCTCTATGGAAAACT
TAGAAGAAGCAGTAAAAAGAATGAAAGAATTTATGTCAAAGTTTTAA

Upstream 100 bases:

>100_bases
AGCACTCCACCTTTTTAAGTTGGAGTGTTTTTTATATAGAGGATTTTTAAGATTTTTGTAGAACTATAATAATAAAACTA
TTGTTTTAGGAGGATTAGAG

Downstream 100 bases:

>100_bases
AAATAAACTGCGGAAGGTGAATAGCTTACCTTCCGCAGTTTATTTTATGCCATTTATTTAGTTTATTTTTGCCACATTTA
TATTGCAAAATGTTAAGCTT

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNFEDKVAKRAKSIEISTIRYFFNMAREVPGAISLAIGEPDFVTPAHIREAAKKALDEGKTGYTVNPGLIELRQEISNYL
NRRYNLSYNPETEILVTIGATEAIYVALNTLVEEGDEVLIPEPSFVAYHPCTILAGAKSVFVPTYEEDDFVLRADVLEKY
ITDRSKVLILPYPNNPTGAVMPKEAMEKIAEVVKKYDLIVVTDEIYSELVYSGFEHVSFASLPDMWERTVTINGFSKSYA
MTGWRLGYIAAPEYFIKHMTKIHQYGVTAAATMCQYAGIEAIKNGDGDILMMREEYDKRRKYLLQSVREMGLDCFEPKGA
FYIFPSIKKTGLTSMEFAKRLLYEAKVAVVPGNAFGENGEGYVRMAYATSMENLEEAVKRMKEFMSKF

Sequences:

>Translated_388_residues
MNFEDKVAKRAKSIEISTIRYFFNMAREVPGAISLAIGEPDFVTPAHIREAAKKALDEGKTGYTVNPGLIELRQEISNYL
NRRYNLSYNPETEILVTIGATEAIYVALNTLVEEGDEVLIPEPSFVAYHPCTILAGAKSVFVPTYEEDDFVLRADVLEKY
ITDRSKVLILPYPNNPTGAVMPKEAMEKIAEVVKKYDLIVVTDEIYSELVYSGFEHVSFASLPDMWERTVTINGFSKSYA
MTGWRLGYIAAPEYFIKHMTKIHQYGVTAAATMCQYAGIEAIKNGDGDILMMREEYDKRRKYLLQSVREMGLDCFEPKGA
FYIFPSIKKTGLTSMEFAKRLLYEAKVAVVPGNAFGENGEGYVRMAYATSMENLEEAVKRMKEFMSKF
>Mature_388_residues
MNFEDKVAKRAKSIEISTIRYFFNMAREVPGAISLAIGEPDFVTPAHIREAAKKALDEGKTGYTVNPGLIELRQEISNYL
NRRYNLSYNPETEILVTIGATEAIYVALNTLVEEGDEVLIPEPSFVAYHPCTILAGAKSVFVPTYEEDDFVLRADVLEKY
ITDRSKVLILPYPNNPTGAVMPKEAMEKIAEVVKKYDLIVVTDEIYSELVYSGFEHVSFASLPDMWERTVTINGFSKSYA
MTGWRLGYIAAPEYFIKHMTKIHQYGVTAAATMCQYAGIEAIKNGDGDILMMREEYDKRRKYLLQSVREMGLDCFEPKGA
FYIFPSIKKTGLTSMEFAKRLLYEAKVAVVPGNAFGENGEGYVRMAYATSMENLEEAVKRMKEFMSKF

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=414, Percent_Identity=27.536231884058, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI169881279, Length=414, Percent_Identity=27.536231884058, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI56713254, Length=409, Percent_Identity=29.0953545232274, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI56713256, Length=409, Percent_Identity=29.0953545232274, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI169881281, Length=302, Percent_Identity=26.8211920529801, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI4507369, Length=379, Percent_Identity=26.3852242744063, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI187936925, Length=357, Percent_Identity=24.6498599439776, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI14211921, Length=357, Percent_Identity=24.6498599439776, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI7705897, Length=352, Percent_Identity=22.4431818181818, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI33469970, Length=352, Percent_Identity=22.4431818181818, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI149944424, Length=392, Percent_Identity=21.6836734693878, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1788722, Length=376, Percent_Identity=32.4468085106383, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1786816, Length=359, Percent_Identity=27.8551532033426, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1788627, Length=377, Percent_Identity=28.9124668435013, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787710, Length=396, Percent_Identity=22.7272727272727, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790797, Length=390, Percent_Identity=23.8461538461538, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17567369, Length=395, Percent_Identity=28.8607594936709, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71994472, Length=423, Percent_Identity=28.3687943262411, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI71994476, Length=423, Percent_Identity=28.3687943262411, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17567663, Length=372, Percent_Identity=26.8817204301075, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71981209, Length=402, Percent_Identity=25.6218905472637, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=26.6149870801034, Blast_Score=125, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6320317, Length=391, Percent_Identity=25.0639386189258, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6323118, Length=376, Percent_Identity=25.2659574468085, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28573069, Length=390, Percent_Identity=28.4615384615385, Blast_Score=171, Evalue=9e-43,
Organism=Drosophila melanogaster, GI24646114, Length=390, Percent_Identity=28.4615384615385, Blast_Score=171, Evalue=9e-43,
Organism=Drosophila melanogaster, GI28573067, Length=390, Percent_Identity=28.4615384615385, Blast_Score=171, Evalue=9e-43,
Organism=Drosophila melanogaster, GI28573065, Length=390, Percent_Identity=28.4615384615385, Blast_Score=171, Evalue=9e-43,
Organism=Drosophila melanogaster, GI18859735, Length=392, Percent_Identity=26.0204081632653, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21356535, Length=374, Percent_Identity=24.0641711229947, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641770, Length=400, Percent_Identity=24, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641760, Length=400, Percent_Identity=24, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641768, Length=400, Percent_Identity=24, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641766, Length=400, Percent_Identity=24, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641764, Length=400, Percent_Identity=24, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551451, Length=400, Percent_Identity=24, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43849; Mature: 43849

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFEDKVAKRAKSIEISTIRYFFNMAREVPGAISLAIGEPDFVTPAHIREAAKKALDEGK
CCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
TGYTVNPGLIELRQEISNYLNRRYNLSYNPETEILVTIGATEAIYVALNTLVEEGDEVLI
CCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEC
PEPSFVAYHPCTILAGAKSVFVPTYEEDDFVLRADVLEKYITDRSKVLILPYPNNPTGAV
CCCCEEEECCEEEEECCCEEEEECCCCCCEEEEHHHHHHHHCCCCCEEEEECCCCCCCCC
MPKEAMEKIAEVVKKYDLIVVTDEIYSELVYSGFEHVSFASLPDMWERTVTINGFSKSYA
CCHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCHHHCCHHCCCHHHHCEEEEECCCCCCC
MTGWRLGYIAAPEYFIKHMTKIHQYGVTAAATMCQYAGIEAIKNGDGDILMMREEYDKRR
CCCEEEEEEECHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHEECCCCCEEEEHHHHHHHH
KYLLQSVREMGLDCFEPKGAFYIFPSIKKTGLTSMEFAKRLLYEAKVAVVPGNAFGENGE
HHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCEEEEECCCCCCCCCC
GYVRMAYATSMENLEEAVKRMKEFMSKF
CEEEEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFEDKVAKRAKSIEISTIRYFFNMAREVPGAISLAIGEPDFVTPAHIREAAKKALDEGK
CCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
TGYTVNPGLIELRQEISNYLNRRYNLSYNPETEILVTIGATEAIYVALNTLVEEGDEVLI
CCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEC
PEPSFVAYHPCTILAGAKSVFVPTYEEDDFVLRADVLEKYITDRSKVLILPYPNNPTGAV
CCCCEEEECCEEEEECCCEEEEECCCCCCEEEEHHHHHHHHCCCCCEEEEECCCCCCCCC
MPKEAMEKIAEVVKKYDLIVVTDEIYSELVYSGFEHVSFASLPDMWERTVTINGFSKSYA
CCHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCHHHCCHHCCCHHHHCEEEEECCCCCCC
MTGWRLGYIAAPEYFIKHMTKIHQYGVTAAATMCQYAGIEAIKNGDGDILMMREEYDKRR
CCCEEEEEEECHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHEECCCCCEEEEHHHHHHHH
KYLLQSVREMGLDCFEPKGAFYIFPSIKKTGLTSMEFAKRLLYEAKVAVVPGNAFGENGE
HHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCEEEEECCCCCCCCCC
GYVRMAYATSMENLEEAVKRMKEFMSKF
CEEEEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]