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The map label for this gene is phoR [H]

Identifier: 162149579

GI number: 162149579

Start: 3901730

End: 3902938

Strand: Direct

Name: phoR [H]

Synonym: GDI_3818

Alternate gene names: 162149579

Gene position: 3901730-3902938 (Clockwise)

Preceding gene: 162149578

Following gene: 162149580

Centisome position: 98.92

GC content: 72.54

Gene sequence:

>1209_bases
ATGGCCGGATTGTGGCCCGAGGATGTCGTGGCGGGCATGGCCCTGCTGGCGGCGGGCGGCATGGGGTGGCGGATGGTCGC
CGGGCGGCGCCGGGCCGCCACGGAGGACCCTGGCAGCGATCCCGCCCGCGCGGCCCCGCCTTCGGCGGATGCCCTGTCGC
GCATGATCGAGGTGCTGGACCTGGTGCCGGCGGCCATCCTGGTGCTGGATGCCGGCGGGCGCATCCTGCATGCGGGGCCC
GGGGCGTGGGAACTGTTCGGGGACAGCCTGGGCGCGATCGTGCGGCATCCCGCCGCGCAATCGGCGCTGCTGCGGCTGCA
CGAGGGCGACCGGGCGGAAGTGGACATGGTGCTGGATGTGCCGGTGCGCCGCGCGGTGCGCGCCCAGTTCCGGCGCGTCG
ATATCGGGCGCGGGGAATCGGTGGTGCTGGCGACCCTGCTGGATGTGAGCGAGCAGGACGCGGTGGAGCGCATGCGCACC
GATTTCGTGGCCTATGCCAGCCACGAGCTGCGCACGCCGCTGGCGGCGCTGACGGGGTTCATCGAGACCCTGCGCGGCCC
CGCCGCCGACGATCCGCCGGCGCAGCAGCGTTTCCTGGGCGTCATGGCCGGGCAGGCCGCGCGGATGCAGCGCCTGCTGG
ACCGGCTGCTGATGCTGTCGCGCGTGCAGATGAGCGAGCACCGCAAGCCGCGCGGCCAGGTCGATCCGGCCGCGGTGATC
GCGCGGGTACGCGACGAGACGGCCCCCCTGCTGGATGGTGGGCCGGCCACCCTGCATATCGACATGGCGGACGACCTGCC
GTCCTTCCCCGGTGATTCCGACCAGGTCGTGCAGGTGCTGCTGAACCTGATCGAGAACGCGATCAAATACGGATCGGGCG
AATCCGACCGCGCGGTGCGGATCGGCCTGCGCGTGCGGCAGGCGGCGCCGTCGGCGATGGTGGGAGTGGACGTGGGCGCG
ACCGGCGGGGCGCGAAACGGGATCGCGTTTGCCGTGACGGATAACGGGCCGGGAATCGAGGCCCGGCACCTGCCGCGCCT
GACCGAGCGATTCTATCGCGTCGAAGGCACGGCGGCGCGGCGCACCGGCACCGGCCTGGGGCTGGCGATCGTCAAGCACA
TCATCGACCGCCATGACGGGCGGCTGACCATCGACAGCGTGGTCGGACGGGGGACGGCGTTTACCGTGTGGTTTCCGCTG
GCAGGCTGA

Upstream 100 bases:

>100_bases
GAGGCCGATATCGTCCGCACCGTGCGGGCGGCGGGCTACGCCCTGGACGATCCGCGTCCTTGACGGCGCGGATCGGTCCG
GGCAGCGGCGGGACCTAGGC

Downstream 100 bases:

>100_bases
TGCCGGGCCGGTGTCAGGCCGATGTCTTGGAAGCGTCATGAAACTGTCATGGACACATCACTCCCCTGGCCAGCCGATCC
GGGCTAGGAGAAGGGCAGCC

Product: phosphate regulon, two-component sensor histidine kinase, phoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MAGLWPEDVVAGMALLAAGGMGWRMVAGRRRAATEDPGSDPARAAPPSADALSRMIEVLDLVPAAILVLDAGGRILHAGP
GAWELFGDSLGAIVRHPAAQSALLRLHEGDRAEVDMVLDVPVRRAVRAQFRRVDIGRGESVVLATLLDVSEQDAVERMRT
DFVAYASHELRTPLAALTGFIETLRGPAADDPPAQQRFLGVMAGQAARMQRLLDRLLMLSRVQMSEHRKPRGQVDPAAVI
ARVRDETAPLLDGGPATLHIDMADDLPSFPGDSDQVVQVLLNLIENAIKYGSGESDRAVRIGLRVRQAAPSAMVGVDVGA
TGGARNGIAFAVTDNGPGIEARHLPRLTERFYRVEGTAARRTGTGLGLAIVKHIIDRHDGRLTIDSVVGRGTAFTVWFPL
AG

Sequences:

>Translated_402_residues
MAGLWPEDVVAGMALLAAGGMGWRMVAGRRRAATEDPGSDPARAAPPSADALSRMIEVLDLVPAAILVLDAGGRILHAGP
GAWELFGDSLGAIVRHPAAQSALLRLHEGDRAEVDMVLDVPVRRAVRAQFRRVDIGRGESVVLATLLDVSEQDAVERMRT
DFVAYASHELRTPLAALTGFIETLRGPAADDPPAQQRFLGVMAGQAARMQRLLDRLLMLSRVQMSEHRKPRGQVDPAAVI
ARVRDETAPLLDGGPATLHIDMADDLPSFPGDSDQVVQVLLNLIENAIKYGSGESDRAVRIGLRVRQAAPSAMVGVDVGA
TGGARNGIAFAVTDNGPGIEARHLPRLTERFYRVEGTAARRTGTGLGLAIVKHIIDRHDGRLTIDSVVGRGTAFTVWFPL
AG
>Mature_401_residues
AGLWPEDVVAGMALLAAGGMGWRMVAGRRRAATEDPGSDPARAAPPSADALSRMIEVLDLVPAAILVLDAGGRILHAGPG
AWELFGDSLGAIVRHPAAQSALLRLHEGDRAEVDMVLDVPVRRAVRAQFRRVDIGRGESVVLATLLDVSEQDAVERMRTD
FVAYASHELRTPLAALTGFIETLRGPAADDPPAQQRFLGVMAGQAARMQRLLDRLLMLSRVQMSEHRKPRGQVDPAAVIA
RVRDETAPLLDGGPATLHIDMADDLPSFPGDSDQVVQVLLNLIENAIKYGSGESDRAVRIGLRVRQAAPSAMVGVDVGAT
GGARNGIAFAVTDNGPGIEARHLPRLTERFYRVEGTAARRTGTGLGLAIVKHIIDRHDGRLTIDSVVGRGTAFTVWFPLA
G

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=35.1778656126482, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI145693157, Length=283, Percent_Identity=27.9151943462898, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788393, Length=270, Percent_Identity=29.6296296296296, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=28.8135593220339, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=26.6932270916335, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790300, Length=376, Percent_Identity=27.6595744680851, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789149, Length=266, Percent_Identity=27.8195488721804, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI48994928, Length=261, Percent_Identity=25.2873563218391, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=267, Percent_Identity=24.3445692883895, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786783, Length=271, Percent_Identity=26.5682656826568, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=252, Percent_Identity=26.5873015873016, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790861, Length=256, Percent_Identity=28.90625, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789403, Length=217, Percent_Identity=29.9539170506912, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87081816, Length=259, Percent_Identity=26.6409266409266, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42860; Mature: 42729

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLWPEDVVAGMALLAAGGMGWRMVAGRRRAATEDPGSDPARAAPPSADALSRMIEVLD
CCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LVPAAILVLDAGGRILHAGPGAWELFGDSLGAIVRHPAAQSALLRLHEGDRAEVDMVLDV
HHHHHHEEECCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECC
PVRRAVRAQFRRVDIGRGESVVLATLLDVSEQDAVERMRTDFVAYASHELRTPLAALTGF
HHHHHHHHHHHHCCCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IETLRGPAADDPPAQQRFLGVMAGQAARMQRLLDRLLMLSRVQMSEHRKPRGQVDPAAVI
HHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
ARVRDETAPLLDGGPATLHIDMADDLPSFPGDSDQVVQVLLNLIENAIKYGSGESDRAVR
HHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEE
IGLRVRQAAPSAMVGVDVGATGGARNGIAFAVTDNGPGIEARHLPRLTERFYRVEGTAAR
EEEHHHHCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHH
RTGTGLGLAIVKHIIDRHDGRLTIDSVVGRGTAFTVWFPLAG
CCCCCHHHHHHHHHHHCCCCCEEHHHHHCCCEEEEEEEECCC
>Mature Secondary Structure 
AGLWPEDVVAGMALLAAGGMGWRMVAGRRRAATEDPGSDPARAAPPSADALSRMIEVLD
CCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LVPAAILVLDAGGRILHAGPGAWELFGDSLGAIVRHPAAQSALLRLHEGDRAEVDMVLDV
HHHHHHEEECCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECC
PVRRAVRAQFRRVDIGRGESVVLATLLDVSEQDAVERMRTDFVAYASHELRTPLAALTGF
HHHHHHHHHHHHCCCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IETLRGPAADDPPAQQRFLGVMAGQAARMQRLLDRLLMLSRVQMSEHRKPRGQVDPAAVI
HHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
ARVRDETAPLLDGGPATLHIDMADDLPSFPGDSDQVVQVLLNLIENAIKYGSGESDRAVR
HHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEE
IGLRVRQAAPSAMVGVDVGATGGARNGIAFAVTDNGPGIEARHLPRLTERFYRVEGTAAR
EEEHHHHCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHH
RTGTGLGLAIVKHIIDRHDGRLTIDSVVGRGTAFTVWFPLAG
CCCCCHHHHHHHHHHHCCCCCEEHHHHHCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]