Click here to switch to the map view.

The map label for this gene is lsrC [H]

Identifier: 162149490

GI number: 162149490

Start: 3812956

End: 3813744

Strand: Direct

Name: lsrC [H]

Synonym: GDI_3728

Alternate gene names: 162149490

Gene position: 3812956-3813744 (Clockwise)

Preceding gene: 162149488

Following gene: 162149491

Centisome position: 96.67

GC content: 68.06

Gene sequence:

>789_bases
ATGCACCACCAAATCCCGGGACCAAACACCTATGTGACCGCGGATTTCGCGGCGCACCATCCGCAGGCGGGGCTGCTGCT
GCCCGTGATCGCGGTCACGCTGGGCGGGGCGCTGGGGGCGATCAACGGGCTGCTGGTCGCGTATGGCCGCATTTCGCCGC
TGATCGCGACGCTGGGCACGATGTCGCTTTATCGTGGCGTGACCTACATCTATGCCCACGGGCAGGAAGTGACCGCCAGC
CGCCTGCCGCACTGGGTGCTGGCCTTCGTCGATTTGCGCATCGCCGGCGTGCCGGCCCTGGTGCTGCTGTCCGCGATCGT
GGTGGGGATGACCGCGTTCTTCCTGCGCCATCTTCCCCTGGGACGGCGGATCTATGCCGTGGGGTCGAATGCCACCGCCA
GCCTGTTCTGCGGCCTGCGCACCGAACGCGTCGTGCTGTTCGCCTACATCCTGTGCGGCGTGATGTGCGGATTTGCCGGC
CTGCTCTATGCCGCGCGGGTGGGCACCGTGACCGTGGTGCTGGCGTCCGGCTGGGAACTGTCCTCGCTGGCCGCCGCCGT
GCTGGGGGGGATCAGCGTTGCCGGCGGGTCCGGGTCCGTCATCGGCGCGGCCCTGGGCGCCATCCTGCTGTCCATGATCG
ATAATGGACTGGTGCTGCTGCATATTCCCGAATTCTGGCGCATCTTCGTGCAGGGGTGCGCCATCGTGCTGGCCATCGCG
GCCGATGGCGCCGTGGCGCGCCAGGTCCGCCTGGCGCTGCGTGCCCAACGTATTGCGAGGATGCCCTGA

Upstream 100 bases:

>100_bases
CTCTTGACTATGTTGTATCGCTCGACGGACTGCCGCTGTCGTCGTGGCGCTTCCGTGGTGAACCTGGCCCATAGCGCATC
CTTCCACTCATGTGAAAATA

Downstream 100 bases:

>100_bases
TGAAACGCGCGGATCGCTGGTTGCGGTGGCGCCCCACCGCCTGGGAGGCGTGCCTGGTCGCGCTGATTTTGATGGCCGGG
GCGTGGTCGGCCTATCTCTC

Product: ABC transporter permease

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: AI-2 import system permease protein lsrC [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MHHQIPGPNTYVTADFAAHHPQAGLLLPVIAVTLGGALGAINGLLVAYGRISPLIATLGTMSLYRGVTYIYAHGQEVTAS
RLPHWVLAFVDLRIAGVPALVLLSAIVVGMTAFFLRHLPLGRRIYAVGSNATASLFCGLRTERVVLFAYILCGVMCGFAG
LLYAARVGTVTVVLASGWELSSLAAAVLGGISVAGGSGSVIGAALGAILLSMIDNGLVLLHIPEFWRIFVQGCAIVLAIA
ADGAVARQVRLALRAQRIARMP

Sequences:

>Translated_262_residues
MHHQIPGPNTYVTADFAAHHPQAGLLLPVIAVTLGGALGAINGLLVAYGRISPLIATLGTMSLYRGVTYIYAHGQEVTAS
RLPHWVLAFVDLRIAGVPALVLLSAIVVGMTAFFLRHLPLGRRIYAVGSNATASLFCGLRTERVVLFAYILCGVMCGFAG
LLYAARVGTVTVVLASGWELSSLAAAVLGGISVAGGSGSVIGAALGAILLSMIDNGLVLLHIPEFWRIFVQGCAIVLAIA
ADGAVARQVRLALRAQRIARMP
>Mature_262_residues
MHHQIPGPNTYVTADFAAHHPQAGLLLPVIAVTLGGALGAINGLLVAYGRISPLIATLGTMSLYRGVTYIYAHGQEVTAS
RLPHWVLAFVDLRIAGVPALVLLSAIVVGMTAFFLRHLPLGRRIYAVGSNATASLFCGLRTERVVLFAYILCGVMCGFAG
LLYAARVGTVTVVLASGWELSSLAAAVLGGISVAGGSGSVIGAALGAILLSMIDNGLVLLHIPEFWRIFVQGCAIVLAIA
ADGAVARQVRLALRAQRIARMP

Specific function: Part of the ABC transporter complex lsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790191, Length=208, Percent_Identity=36.5384615384615, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1787793, Length=242, Percent_Identity=37.1900826446281, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790524, Length=207, Percent_Identity=30.9178743961353, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788896, Length=205, Percent_Identity=34.1463414634146, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1789992, Length=136, Percent_Identity=38.2352941176471, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI145693152, Length=216, Percent_Identity=28.7037037037037, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788471, Length=233, Percent_Identity=32.1888412017167, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787794, Length=187, Percent_Identity=25.1336898395722, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87082395, Length=197, Percent_Identity=28.4263959390863, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 27302; Mature: 27302

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHQIPGPNTYVTADFAAHHPQAGLLLPVIAVTLGGALGAINGLLVAYGRISPLIATLGT
CCCCCCCCCCEEEECHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSLYRGVTYIYAHGQEVTASRLPHWVLAFVDLRIAGVPALVLLSAIVVGMTAFFLRHLPL
HHHHCCEEEEEECCCCHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
GRRIYAVGSNATASLFCGLRTERVVLFAYILCGVMCGFAGLLYAARVGTVTVVLASGWEL
CCEEEEECCCCHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCH
SSLAAAVLGGISVAGGSGSVIGAALGAILLSMIDNGLVLLHIPEFWRIFVQGCAIVLAIA
HHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHH
ADGAVARQVRLALRAQRIARMP
CCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHHQIPGPNTYVTADFAAHHPQAGLLLPVIAVTLGGALGAINGLLVAYGRISPLIATLGT
CCCCCCCCCCEEEECHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSLYRGVTYIYAHGQEVTASRLPHWVLAFVDLRIAGVPALVLLSAIVVGMTAFFLRHLPL
HHHHCCEEEEEECCCCHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
GRRIYAVGSNATASLFCGLRTERVVLFAYILCGVMCGFAGLLYAARVGTVTVVLASGWEL
CCEEEEECCCCHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCH
SSLAAAVLGGISVAGGSGSVIGAALGAILLSMIDNGLVLLHIPEFWRIFVQGCAIVLAIA
HHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHH
ADGAVARQVRLALRAQRIARMP
CCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA