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The map label for this gene is pdxA [H]

Identifier: 162146776

GI number: 162146776

Start: 975162

End: 976079

Strand: Reverse

Name: pdxA [H]

Synonym: GDI_0958

Alternate gene names: 162146776

Gene position: 976079-975162 (Counterclockwise)

Preceding gene: 162146783

Following gene: 162146775

Centisome position: 24.75

GC content: 64.16

Gene sequence:

>918_bases
ATGTTTCTACGGCGACCGGCGCAACGGCGCTGGATCGTCGTCGGCGATCCTCTGGTGATGCGTCATGCGCTGGCCGGGCT
CGATCCAGCGGCGCACGTGCGCCGGATCACAACATTGGCCGAAGCCCGCTTCGACGACGACGTGCTGCACGTCCTGGCGT
CGTCGGAGTGTGCGTCCCTGCCGCCCGTGGGTCAGATCACCGTCGAAAGTGGCCGCGCCGCCTATGCGGCGATCCTTTTC
GCGGTCCAATTGGCGAAGAACGGGACAGTAGGCGGCATCGTCACCGCACCGATCCACAAGGAAGCGCTCGCTGCCGCCGG
GCTGCACTACCCCGGCCATACGGAAATTCTCGCCGAACAGGCCGACGGTGCGACTGTCGCCATGATGCTGGCGAACGAGG
ATATCCGCGTCGTGCTGGTGACCATCCATTGTTCGCTGCAAGACGCAATCCAGCGTGCCGATTTTCCCGCGCAGATGGCG
GCGATCCGTCTGGCCCACGCTGGCGCGCGGGCTCAGGGCATCGAACAGCCGCGTGTCGCAGTTGCCGGTCTCAATCCCCA
TGCCGGAGAAGGTGGCCTGTTCGGTCATGAGGAAGCCCGCATCATCGCGCCCGCCATTGCACAAGCTCGGAGCGAGGGCA
TCGATGCGTCCGGTCCGTGGCCGGGCGACACCGTGTTCATGCAGGCACGCGAAAGTCGCTTCGATGTCGTGGTCGCGCAA
TATCATGACCAGGGGCTGATCCCGGTGAAATATATGGGTCTGGCACAAGGGGTGAACATCACGCTCGGCCTGCCGTTTGT
GCGCACGAGCCCCGACCACGGCACTGCTTTTGACATCGCGGGGCGCGGTATCGCCGATCCCTCCAGTCTGGAGACCGCGT
TTGATTACGCTCTTCGCCTTACCGGAGTCACAGTATGA

Upstream 100 bases:

>100_bases
TATTGTCACCATCATGAGCGAAACACCTTCCTTCAGTCTCCAGCCGTTGGCGGTCACGATGGGCGATCCCGCCGGGATCG
GACCGGAAATCGTGGCCCGG

Downstream 100 bases:

>100_bases
CCCGCCCCGATTTCATCTTCATGCTGACTCGTCACGACCGGACGGTGGAGAATGCGGTCGATCTGGTTGAAATCGTCCGT
GCTGCCGGTGTCCGTCATAT

Product: 4-hydroxythreonine-4-phosphate dehydrogenase 2

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MFLRRPAQRRWIVVGDPLVMRHALAGLDPAAHVRRITTLAEARFDDDVLHVLASSECASLPPVGQITVESGRAAYAAILF
AVQLAKNGTVGGIVTAPIHKEALAAAGLHYPGHTEILAEQADGATVAMMLANEDIRVVLVTIHCSLQDAIQRADFPAQMA
AIRLAHAGARAQGIEQPRVAVAGLNPHAGEGGLFGHEEARIIAPAIAQARSEGIDASGPWPGDTVFMQARESRFDVVVAQ
YHDQGLIPVKYMGLAQGVNITLGLPFVRTSPDHGTAFDIAGRGIADPSSLETAFDYALRLTGVTV

Sequences:

>Translated_305_residues
MFLRRPAQRRWIVVGDPLVMRHALAGLDPAAHVRRITTLAEARFDDDVLHVLASSECASLPPVGQITVESGRAAYAAILF
AVQLAKNGTVGGIVTAPIHKEALAAAGLHYPGHTEILAEQADGATVAMMLANEDIRVVLVTIHCSLQDAIQRADFPAQMA
AIRLAHAGARAQGIEQPRVAVAGLNPHAGEGGLFGHEEARIIAPAIAQARSEGIDASGPWPGDTVFMQARESRFDVVVAQ
YHDQGLIPVKYMGLAQGVNITLGLPFVRTSPDHGTAFDIAGRGIADPSSLETAFDYALRLTGVTV
>Mature_305_residues
MFLRRPAQRRWIVVGDPLVMRHALAGLDPAAHVRRITTLAEARFDDDVLHVLASSECASLPPVGQITVESGRAAYAAILF
AVQLAKNGTVGGIVTAPIHKEALAAAGLHYPGHTEILAEQADGATVAMMLANEDIRVVLVTIHCSLQDAIQRADFPAQMA
AIRLAHAGARAQGIEQPRVAVAGLNPHAGEGGLFGHEEARIIAPAIAQARSEGIDASGPWPGDTVFMQARESRFDVVVAQ
YHDQGLIPVKYMGLAQGVNITLGLPFVRTSPDHGTAFDIAGRGIADPSSLETAFDYALRLTGVTV

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=239, Percent_Identity=44.7698744769874, Blast_Score=200, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 32258; Mature: 32258

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLRRPAQRRWIVVGDPLVMRHALAGLDPAAHVRRITTLAEARFDDDVLHVLASSECASL
CCCCCCCCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
PPVGQITVESGRAAYAAILFAVQLAKNGTVGGIVTAPIHKEALAAAGLHYPGHTEILAEQ
CCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHCCCCCCCHHHEEEC
ADGATVAMMLANEDIRVVLVTIHCSLQDAIQRADFPAQMAAIRLAHAGARAQGIEQPRVA
CCCCEEEEEEECCCEEEEEEEEECCHHHHHHHCCCCHHHHHHHHHHCCCHHCCCCCCCEE
VAGLNPHAGEGGLFGHEEARIIAPAIAQARSEGIDASGPWPGDTVFMQARESRFDVVVAQ
EEECCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEE
YHDQGLIPVKYMGLAQGVNITLGLPFVRTSPDHGTAFDIAGRGIADPSSLETAFDYALRL
ECCCCCCEEEEHHHHCCCEEEEECCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHEEE
TGVTV
EEECC
>Mature Secondary Structure
MFLRRPAQRRWIVVGDPLVMRHALAGLDPAAHVRRITTLAEARFDDDVLHVLASSECASL
CCCCCCCCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
PPVGQITVESGRAAYAAILFAVQLAKNGTVGGIVTAPIHKEALAAAGLHYPGHTEILAEQ
CCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHCCCCCCCHHHEEEC
ADGATVAMMLANEDIRVVLVTIHCSLQDAIQRADFPAQMAAIRLAHAGARAQGIEQPRVA
CCCCEEEEEEECCCEEEEEEEEECCHHHHHHHCCCCHHHHHHHHHHCCCHHCCCCCCCEE
VAGLNPHAGEGGLFGHEEARIIAPAIAQARSEGIDASGPWPGDTVFMQARESRFDVVVAQ
EEECCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEE
YHDQGLIPVKYMGLAQGVNITLGLPFVRTSPDHGTAFDIAGRGIADPSSLETAFDYALRL
ECCCCCCEEEEHHHHCCCEEEEECCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHEEE
TGVTV
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA