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The map label for this gene is cobT [H]

Identifier: 162146667

GI number: 162146667

Start: 862485

End: 863537

Strand: Reverse

Name: cobT [H]

Synonym: GDI_0845

Alternate gene names: 162146667

Gene position: 863537-862485 (Counterclockwise)

Preceding gene: 162146669

Following gene: 162146666

Centisome position: 21.89

GC content: 74.83

Gene sequence:

>1053_bases
ATGCCAGCCCCGCGCCGCACCTCCCTGCCCTTTCCCACGCCGGATGCCCTGCGCGCGGCCTGCGCGGACCTGCCGCCGCC
GGACGAGGCGGCACGGTACGCCATCGCCGCACGCGAGGCCACGCTGACGAAGCCGCCCGGCAGCCTGGGACGCCTGGAAG
AACTGGCGGCGTGGCTGGGGGCATGGCAGGGCCGGGAGAGACCGGCGCTGGACCGGGTGCGGGTGGTCGTCTTCGCCGGC
AACCACGGGGTCGTCGCGCGGGGCGTGTCGCCATGGCCCGCCAGCGTCACCGCGCAGATGGTCGCCAATTTCGCGGCGGG
TGGGGCGGCGATCAACCAGATCGCGCGCGTCGCCGGGGCCGGGCTGACGGTGGTGCCCATGATGGACCTGGCCCCGACCG
CGGATTTCACCGTCGCCCCGGCCATGGACCAGGACGCATTCCTGGCGGCGGTCGCCACCGGCCATGACGCGGTCGAAGCG
GAAACCGACCTGCTGTGCCTGGGCGAGATGGGGATCGGCAACACCACCGCCGCCGCCGCGCTGGCGGCATCCCTGTACGG
CGGCAGCGGCGCGGACTGGGCCGGACCGGGCGCGGGATCGGACGCGGACGGCGTGGCGCGCAAGGCCCGGACGATCGACG
CCGCGCTGGCCCGTCACGCCGGCCACGCCGGCGACCCGCTGGCACTGGCGCGGTGCCTGGGCGGGTACGAAATGGCGGCC
ATCCTGGGCGCGGTCCTGGCGGCGCGGCAGAAGCGCGTGCCGGTCGTGCTGGACGGGTTCATCTGCACGGCGGCGGCGGC
GCCCCTGCTGCGGCTGAACCCGGACGGGCTGGCCCATACCGTCCTGTCGCACCGGTCGGCCGAGGCCGCTCATGGCGTCC
TGGCCCGGCATCTGGGGCTGGAACCGTTGCTGAATCTGGGCCTGCGCCTGGGCGAGGCATCGGGCGCGGCGCTGGCCGTG
CCGCTGCTGCGCGCGGCGGCAGCCTGTCATGGCGGCATGGCGACATTCGCCGAGGCCGAAGTCAGCGAGAAGAAAGTCAG
CGGGGAAACATGA

Upstream 100 bases:

>100_bases
GTCTGTCCGCCCCGCATCCCGCCGGTTCCATCGCGCGCCCCCCGTTGTCCCCCACCACGCTGTCTTGCATCGCGGCGCAT
AACGCCACACAAAAAGCGCC

Downstream 100 bases:

>100_bases
CCTGGCTTACCCGAGTCCGCGCGGACCTCGCCACGGGCCTGGGCCTGCTGACCCGGCTGCCGGTGTCCTGGCTGGCGCGG
GGCAGCACGGGCGTCGACCT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferas

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MPAPRRTSLPFPTPDALRAACADLPPPDEAARYAIAAREATLTKPPGSLGRLEELAAWLGAWQGRERPALDRVRVVVFAG
NHGVVARGVSPWPASVTAQMVANFAAGGAAINQIARVAGAGLTVVPMMDLAPTADFTVAPAMDQDAFLAAVATGHDAVEA
ETDLLCLGEMGIGNTTAAAALAASLYGGSGADWAGPGAGSDADGVARKARTIDAALARHAGHAGDPLALARCLGGYEMAA
ILGAVLAARQKRVPVVLDGFICTAAAAPLLRLNPDGLAHTVLSHRSAEAAHGVLARHLGLEPLLNLGLRLGEASGAALAV
PLLRAAAACHGGMATFAEAEVSEKKVSGET

Sequences:

>Translated_350_residues
MPAPRRTSLPFPTPDALRAACADLPPPDEAARYAIAAREATLTKPPGSLGRLEELAAWLGAWQGRERPALDRVRVVVFAG
NHGVVARGVSPWPASVTAQMVANFAAGGAAINQIARVAGAGLTVVPMMDLAPTADFTVAPAMDQDAFLAAVATGHDAVEA
ETDLLCLGEMGIGNTTAAAALAASLYGGSGADWAGPGAGSDADGVARKARTIDAALARHAGHAGDPLALARCLGGYEMAA
ILGAVLAARQKRVPVVLDGFICTAAAAPLLRLNPDGLAHTVLSHRSAEAAHGVLARHLGLEPLLNLGLRLGEASGAALAV
PLLRAAAACHGGMATFAEAEVSEKKVSGET
>Mature_349_residues
PAPRRTSLPFPTPDALRAACADLPPPDEAARYAIAAREATLTKPPGSLGRLEELAAWLGAWQGRERPALDRVRVVVFAGN
HGVVARGVSPWPASVTAQMVANFAAGGAAINQIARVAGAGLTVVPMMDLAPTADFTVAPAMDQDAFLAAVATGHDAVEAE
TDLLCLGEMGIGNTTAAAALAASLYGGSGADWAGPGAGSDADGVARKARTIDAALARHAGHAGDPLALARCLGGYEMAAI
LGAVLAARQKRVPVVLDGFICTAAAAPLLRLNPDGLAHTVLSHRSAEAAHGVLARHLGLEPLLNLGLRLGEASGAALAVP
LLRAAAACHGGMATFAEAEVSEKKVSGET

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=319, Percent_Identity=32.2884012539185, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 35326; Mature: 35195

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPRRTSLPFPTPDALRAACADLPPPDEAARYAIAAREATLTKPPGSLGRLEELAAWLG
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
AWQGRERPALDRVRVVVFAGNHGVVARGVSPWPASVTAQMVANFAAGGAAINQIARVAGA
HHCCCCCCCCCCEEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCC
GLTVVPMMDLAPTADFTVAPAMDQDAFLAAVATGHDAVEAETDLLCLGEMGIGNTTAAAA
CEEEEEHHCCCCCCCEEECCCCCCCHHEEEECCCCHHHCCCCCEEEEECCCCCCHHHHHH
LAASLYGGSGADWAGPGAGSDADGVARKARTIDAALARHAGHAGDPLALARCLGGYEMAA
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHH
ILGAVLAARQKRVPVVLDGFICTAAAAPLLRLNPDGLAHTVLSHRSAEAAHGVLARHLGL
HHHHHHHHHHCCCCEEECHHHHHHHHCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHCH
EPLLNLGLRLGEASGAALAVPLLRAAAACHGGMATFAEAEVSEKKVSGET
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PAPRRTSLPFPTPDALRAACADLPPPDEAARYAIAAREATLTKPPGSLGRLEELAAWLG
CCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
AWQGRERPALDRVRVVVFAGNHGVVARGVSPWPASVTAQMVANFAAGGAAINQIARVAGA
HHCCCCCCCCCCEEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCC
GLTVVPMMDLAPTADFTVAPAMDQDAFLAAVATGHDAVEAETDLLCLGEMGIGNTTAAAA
CEEEEEHHCCCCCCCEEECCCCCCCHHEEEECCCCHHHCCCCCEEEEECCCCCCHHHHHH
LAASLYGGSGADWAGPGAGSDADGVARKARTIDAALARHAGHAGDPLALARCLGGYEMAA
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHH
ILGAVLAARQKRVPVVLDGFICTAAAAPLLRLNPDGLAHTVLSHRSAEAAHGVLARHLGL
HHHHHHHHHHCCCCEEECHHHHHHHHCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHCH
EPLLNLGLRLGEASGAALAVPLLRAAAACHGGMATFAEAEVSEKKVSGET
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]