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The map label for this gene is ntrY [H]

Identifier: 161870940

GI number: 161870940

Start: 2077787

End: 2079907

Strand: Reverse

Name: ntrY [H]

Synonym: NMCC_2034

Alternate gene names: 161870940

Gene position: 2079907-2077787 (Counterclockwise)

Preceding gene: 161870941

Following gene: 161870939

Centisome position: 96.59

GC content: 57.43

Gene sequence:

>2121_bases
ATGCGCCGTTTTCTACCGATCGCAGCCATATGCGCCGTCGTCCTGTTGTACGGACTGACGGCGGCAACCGGCAGCACCAG
TTCGCTGGCGGATTATTTCTGGTGGATTGTTGCGTTCAGCGCAATGCTGCTGCTGGTGTTGTCCGCCGTTTTGGCACGTT
ATGTCATATTGCTGTTGAAAGACAGGCGCGACGGCGTATTCGGTTCGCAGATTGCCAAACGCCTTTCTGGGATGTTTACG
CTGGTTGCCGTACTGCCCGGCGTGTTTCTGTTCGGCGTTTCCGCACAGTTTATCAACGGCACGATTAATTCGTGGTTCGG
CAACGATACCCACGAGGCGCTTGAACGCAGCCTCAATTTGAGCAAGTCCGCATTGAATTTGGCGGCAGACAACGCCCTCG
GCAACGCCGTCCCCGTGCAGATAGACCTCATCGGCGCGGCTTCCCTGCCCGGGGATATGGGCAGGGTGCTGGAACATTAC
GCCGGCAGCGGTTTTGCCCAGCTTGCCCTGTACAATGCCGCAAGCGGCAAAATCGAAAAAAGCATCAACCCGCACAAGCT
CGATCAGCCGTTTCCGGATAAGGCGCGTTGGGAAAAAATCCAACAGGCGGGTTCGGTCAGGGATTTGGAAAGCATAGGCG
GCGTATTGTACGCGCAGGGCTGGTTGTCGGCGGGTACGCACAACGGGCGCGATTACGCCTTGTTTTTCCGTCAGCCGGTT
CCCAAAGGCGTGGCAGAGGATGCCGTCTTAATCGAAAAGGCAAGGGCGAAATATGCTGAGTTGAGTTACAGCAAAAAAGG
TTTGCAGACCTTTTTCCTGGCAACCCTGCTGATTGCCTCGCTGCTGTCGATTTTTCTTGCACTGGTCATGGCACTGTATT
TCGCCCGCCGTTTCGTCGAACCCGTCCTATCGCTTGCCGAGGGGGCGAGGGCGGTGGCGCAAGGCGATTTCAGCCAGACG
CGCCCCGTGTTGCGCAACGACGAGTTCGGACGCTTGACCAAGTTGTTCAACCACATGACCGAGCAGCTTTCCATCGCCAA
AGAAGCAGACGAGCGCAACAGGAGGCGCGAAGAAGCCGCCAGACATTATCTTGAATGCGTGTTGGAGGGGCTGACCACGG
GCGTGGTGGTGTTTGACGAACAAGGCTGTCTGAAAACCTTCAACAAAGCGGCGGAACAGATTTTGGGGATGCCGCTTACC
CCCCTGTGGGGCAGCAGCCGGCACGGTTGGCACGGCGTTTCGGCGCAGCAGTCCCTGCTTGCCGAAGTGTTTGCCGCCAT
CGGCGCGGCGGCAGGTACGGACAAACCGGTCCATGTGAAATATGCCGCGCCGGACGATGCCAAAATCCTGCTGGGCAAGG
CAACCGTCCTGCCCGAAGACAACGGCAACGGCGTGGTGATGGTGATTGACGACATCACCGTGCTGATACACGCGCAAAAA
GAAGCCGCGTGGGGCGAAGTGGCGAAGCGGCTGGCACACGAAATCCGCAATCCGCTCACGCCCATCCAGCTTTCCGCCGA
ACGGCTGGCGTGGAAATTGGGCGGGAAGCTGGATGAGCAGGATGCGCAAATCCTGACGCGTTCGACCGACACCATCGTCA
AACAGGTGGCGGCATTGAAGGAAATGGTCGAAGCATTCCGCAATTATGCGCGTTCCCCTTCGCTCAAATTGGAAAATCAG
GATTTGAACGCCTTAATCGGCGATGTGTTGGCATTGTATGAAGCCGGTCCGTGCCGGTTTGCGGCGGAGCTTGCCGGCGA
ACCGCTGATGGTGGCGGCGGATACGACCGCCATGCGGCAGGTGCTGCACAATATTTTCAAAAATGCCGCCGAAGCGGCGG
AAGAAGCCGATGTACCCGAAGTCAGGGTAAAATCGGAAGCGGGGCAGGACGGTCGGATTGTCCTGACGGTTTGCGACAAC
GGCAAAGGGTTCGGCAGGGAAATGCTGCACAACGCCTTCGAGCCGTATGTAACGGACAAACCGGCGGGAACGGGATTGGG
TCTGCCTGTGGTGAAAAAAATCATTGAAGAACACGGCGGCCGCATCAGTTTGAGCAATCAGGATGCGGGTGGCGCGTGTG
TCAGAATCATCTTGCCAAAAACGGTAAAAACTTATGCGTAG

Upstream 100 bases:

>100_bases
CTTCAAAACTGCCCAAGCCTTTTCAAATCAATGCATTGACTTCTCAAAACTGGCATTTGGATTCGGGTTGGAAACCTCTA
AACATCATCGGGAACAAATA

Downstream 100 bases:

>100_bases
CAGCGATATTTTAATTGTAGACGACGAAATCGGCATCCGCGACCTGCTGTCGGAAATCCTGCAGGACGAAGGTTATTCGG
TCGCATTGGCGGAAAACGCC

Product: nitrogen regulation protein NtrY, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MRRFLPIAAICAVVLLYGLTAATGSTSSLADYFWWIVAFSAMLLLVLSAVLARYVILLLKDRRDGVFGSQIAKRLSGMFT
LVAVLPGVFLFGVSAQFINGTINSWFGNDTHEALERSLNLSKSALNLAADNALGNAVPVQIDLIGAASLPGDMGRVLEHY
AGSGFAQLALYNAASGKIEKSINPHKLDQPFPDKARWEKIQQAGSVRDLESIGGVLYAQGWLSAGTHNGRDYALFFRQPV
PKGVAEDAVLIEKARAKYAELSYSKKGLQTFFLATLLIASLLSIFLALVMALYFARRFVEPVLSLAEGARAVAQGDFSQT
RPVLRNDEFGRLTKLFNHMTEQLSIAKEADERNRRREEAARHYLECVLEGLTTGVVVFDEQGCLKTFNKAAEQILGMPLT
PLWGSSRHGWHGVSAQQSLLAEVFAAIGAAAGTDKPVHVKYAAPDDAKILLGKATVLPEDNGNGVVMVIDDITVLIHAQK
EAAWGEVAKRLAHEIRNPLTPIQLSAERLAWKLGGKLDEQDAQILTRSTDTIVKQVAALKEMVEAFRNYARSPSLKLENQ
DLNALIGDVLALYEAGPCRFAAELAGEPLMVAADTTAMRQVLHNIFKNAAEAAEEADVPEVRVKSEAGQDGRIVLTVCDN
GKGFGREMLHNAFEPYVTDKPAGTGLGLPVVKKIIEEHGGRISLSNQDAGGACVRIILPKTVKTYA

Sequences:

>Translated_706_residues
MRRFLPIAAICAVVLLYGLTAATGSTSSLADYFWWIVAFSAMLLLVLSAVLARYVILLLKDRRDGVFGSQIAKRLSGMFT
LVAVLPGVFLFGVSAQFINGTINSWFGNDTHEALERSLNLSKSALNLAADNALGNAVPVQIDLIGAASLPGDMGRVLEHY
AGSGFAQLALYNAASGKIEKSINPHKLDQPFPDKARWEKIQQAGSVRDLESIGGVLYAQGWLSAGTHNGRDYALFFRQPV
PKGVAEDAVLIEKARAKYAELSYSKKGLQTFFLATLLIASLLSIFLALVMALYFARRFVEPVLSLAEGARAVAQGDFSQT
RPVLRNDEFGRLTKLFNHMTEQLSIAKEADERNRRREEAARHYLECVLEGLTTGVVVFDEQGCLKTFNKAAEQILGMPLT
PLWGSSRHGWHGVSAQQSLLAEVFAAIGAAAGTDKPVHVKYAAPDDAKILLGKATVLPEDNGNGVVMVIDDITVLIHAQK
EAAWGEVAKRLAHEIRNPLTPIQLSAERLAWKLGGKLDEQDAQILTRSTDTIVKQVAALKEMVEAFRNYARSPSLKLENQ
DLNALIGDVLALYEAGPCRFAAELAGEPLMVAADTTAMRQVLHNIFKNAAEAAEEADVPEVRVKSEAGQDGRIVLTVCDN
GKGFGREMLHNAFEPYVTDKPAGTGLGLPVVKKIIEEHGGRISLSNQDAGGACVRIILPKTVKTYA
>Mature_706_residues
MRRFLPIAAICAVVLLYGLTAATGSTSSLADYFWWIVAFSAMLLLVLSAVLARYVILLLKDRRDGVFGSQIAKRLSGMFT
LVAVLPGVFLFGVSAQFINGTINSWFGNDTHEALERSLNLSKSALNLAADNALGNAVPVQIDLIGAASLPGDMGRVLEHY
AGSGFAQLALYNAASGKIEKSINPHKLDQPFPDKARWEKIQQAGSVRDLESIGGVLYAQGWLSAGTHNGRDYALFFRQPV
PKGVAEDAVLIEKARAKYAELSYSKKGLQTFFLATLLIASLLSIFLALVMALYFARRFVEPVLSLAEGARAVAQGDFSQT
RPVLRNDEFGRLTKLFNHMTEQLSIAKEADERNRRREEAARHYLECVLEGLTTGVVVFDEQGCLKTFNKAAEQILGMPLT
PLWGSSRHGWHGVSAQQSLLAEVFAAIGAAAGTDKPVHVKYAAPDDAKILLGKATVLPEDNGNGVVMVIDDITVLIHAQK
EAAWGEVAKRLAHEIRNPLTPIQLSAERLAWKLGGKLDEQDAQILTRSTDTIVKQVAALKEMVEAFRNYARSPSLKLENQ
DLNALIGDVLALYEAGPCRFAAELAGEPLMVAADTTAMRQVLHNIFKNAAEAAEEADVPEVRVKSEAGQDGRIVLTVCDN
GKGFGREMLHNAFEPYVTDKPAGTGLGLPVVKKIIEEHGGRISLSNQDAGGACVRIILPKTVKTYA

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=420, Percent_Identity=25, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=34.9344978165939, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1789808, Length=244, Percent_Identity=27.0491803278689, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=28.125, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76529; Mature: 76529

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRFLPIAAICAVVLLYGLTAATGSTSSLADYFWWIVAFSAMLLLVLSAVLARYVILLLK
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRRDGVFGSQIAKRLSGMFTLVAVLPGVFLFGVSAQFINGTINSWFGNDTHEALERSLNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHCCCCCHHHHHHHHHCC
SKSALNLAADNALGNAVPVQIDLIGAASLPGDMGRVLEHYAGSGFAQLALYNAASGKIEK
HHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHEECCCCCCHHC
SINPHKLDQPFPDKARWEKIQQAGSVRDLESIGGVLYAQGWLSAGTHNGRDYALFFRQPV
CCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECCCC
PKGVAEDAVLIEKARAKYAELSYSKKGLQTFFLATLLIASLLSIFLALVMALYFARRFVE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVLSLAEGARAVAQGDFSQTRPVLRNDEFGRLTKLFNHMTEQLSIAKEADERNRRREEAA
HHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHYLECVLEGLTTGVVVFDEQGCLKTFNKAAEQILGMPLTPLWGSSRHGWHGVSAQQSLL
HHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
AEVFAAIGAAAGTDKPVHVKYAAPDDAKILLGKATVLPEDNGNGVVMVIDDITVLIHAQK
HHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECEEECCCCCCCEEEEEEECEEEEEECCH
EAAWGEVAKRLAHEIRNPLTPIQLSAERLAWKLGGKLDEQDAQILTRSTDTIVKQVAALK
HHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHH
EMVEAFRNYARSPSLKLENQDLNALIGDVLALYEAGPCRFAAELAGEPLMVAADTTAMRQ
HHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEECHHHHHH
VLHNIFKNAAEAAEEADVPEVRVKSEAGQDGRIVLTVCDNGKGFGREMLHNAFEPYVTDK
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCC
PAGTGLGLPVVKKIIEEHGGRISLSNQDAGGACVRIILPKTVKTYA
CCCCCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCHHHCCC
>Mature Secondary Structure
MRRFLPIAAICAVVLLYGLTAATGSTSSLADYFWWIVAFSAMLLLVLSAVLARYVILLLK
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRRDGVFGSQIAKRLSGMFTLVAVLPGVFLFGVSAQFINGTINSWFGNDTHEALERSLNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHCCCCCHHHHHHHHHCC
SKSALNLAADNALGNAVPVQIDLIGAASLPGDMGRVLEHYAGSGFAQLALYNAASGKIEK
HHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHEECCCCCCHHC
SINPHKLDQPFPDKARWEKIQQAGSVRDLESIGGVLYAQGWLSAGTHNGRDYALFFRQPV
CCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECCCC
PKGVAEDAVLIEKARAKYAELSYSKKGLQTFFLATLLIASLLSIFLALVMALYFARRFVE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVLSLAEGARAVAQGDFSQTRPVLRNDEFGRLTKLFNHMTEQLSIAKEADERNRRREEAA
HHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHYLECVLEGLTTGVVVFDEQGCLKTFNKAAEQILGMPLTPLWGSSRHGWHGVSAQQSLL
HHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
AEVFAAIGAAAGTDKPVHVKYAAPDDAKILLGKATVLPEDNGNGVVMVIDDITVLIHAQK
HHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECEEECCCCCCCEEEEEEECEEEEEECCH
EAAWGEVAKRLAHEIRNPLTPIQLSAERLAWKLGGKLDEQDAQILTRSTDTIVKQVAALK
HHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHH
EMVEAFRNYARSPSLKLENQDLNALIGDVLALYEAGPCRFAAELAGEPLMVAADTTAMRQ
HHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEECHHHHHH
VLHNIFKNAAEAAEEADVPEVRVKSEAGQDGRIVLTVCDNGKGFGREMLHNAFEPYVTDK
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCC
PAGTGLGLPVVKKIIEEHGGRISLSNQDAGGACVRIILPKTVKTYA
CCCCCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]