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The map label for this gene is fabZ

Identifier: 161870884

GI number: 161870884

Start: 2025214

End: 2025663

Strand: Direct

Name: fabZ

Synonym: NMCC_1973

Alternate gene names: 161870884

Gene position: 2025214-2025663 (Clockwise)

Preceding gene: 161870883

Following gene: 161870885

Centisome position: 94.05

GC content: 56.89

Gene sequence:

>450_bases
ATGGACGTACAACTCCCCATCGAAGCCAAAGACATCCAAAAACTCATCCCCCACCGCTATCCGTTTCTCCAGCTCGACCG
CATCACCGCCTTCGAGCCGATGAAAACCCTGACCGCGATTAAAAACGTCACCATAAACGAACCCCAGTTCCAAGGCCATT
TTCCCGACCTGCCCGTGATGCCCGGCGTACTCATCATCGAAGCGATGGCGCAGGCGTGCGGCACGTTGGCGATTTTGAGC
GAAGGCGGGCGCAAAGAAAACGAATTCTTCTTCTTCGCCGGCATAGACGAAGCCCGTTTCAAACGCCAAGTCATCCCCGG
CGACCAACTCGTCTTTGAAGTCGAGCTGCTGACCAGCCGGCGCGGCATCGGCAAATTCAACGCCGTTGCCAAAGTGGACG
GGCAAGTCGCCGTCGAAGCCGTGATTATGTGCGCCAAACGCGTGGTTTGA

Upstream 100 bases:

>100_bases
CGAAATGAACAAACGGCTCAAAACACTGGAGCAGCAGCTTTCAGATGCCGGTCAAGACAGCAAATAACCAAACCGACTTT
ATTCAAGGAATACGACAGAC

Downstream 100 bases:

>100_bases
GTGTTCAGAAAAAGGTCGTCTGAAAGTTTTCAGACGACCTGTTGCCGTCGCGCATCTTCGCGGCAACACGACAGGAAAGG
AAAAACATGACCCTCATCCA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MDVQLPIEAKDIQKLIPHRYPFLQLDRITAFEPMKTLTAIKNVTINEPQFQGHFPDLPVMPGVLIIEAMAQACGTLAILS
EGGRKENEFFFFAGIDEARFKRQVIPGDQLVFEVELLTSRRGIGKFNAVAKVDGQVAVEAVIMCAKRVV

Sequences:

>Translated_149_residues
MDVQLPIEAKDIQKLIPHRYPFLQLDRITAFEPMKTLTAIKNVTINEPQFQGHFPDLPVMPGVLIIEAMAQACGTLAILS
EGGRKENEFFFFAGIDEARFKRQVIPGDQLVFEVELLTSRRGIGKFNAVAKVDGQVAVEAVIMCAKRVV
>Mature_149_residues
MDVQLPIEAKDIQKLIPHRYPFLQLDRITAFEPMKTLTAIKNVTINEPQFQGHFPDLPVMPGVLIIEAMAQACGTLAILS
EGGRKENEFFFFAGIDEARFKRQVIPGDQLVFEVELLTSRRGIGKFNAVAKVDGQVAVEAVIMCAKRVV

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=140, Percent_Identity=55, Blast_Score=166, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_NEIG1 (Q5F5W5)

Other databases:

- EMBL:   AE004969
- RefSeq:   YP_208834.1
- ProteinModelPortal:   Q5F5W5
- SMR:   Q5F5W5
- STRING:   Q5F5W5
- EnsemblBacteria:   EBNEIT00000003515
- GeneID:   3282334
- GenomeReviews:   AE004969_GR
- KEGG:   ngo:NGO1804
- eggNOG:   COG0764
- GeneTree:   EBGT00050000020551
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- PhylomeDB:   Q5F5W5
- ProtClustDB:   PRK00006
- BioCyc:   NGON242231:NGO1804-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16613; Mature: 16613

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: ACT_SITE 53-53

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVQLPIEAKDIQKLIPHRYPFLQLDRITAFEPMKTLTAIKNVTINEPQFQGHFPDLPVM
CCCCCCCCHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PGVLIIEAMAQACGTLAILSEGGRKENEFFFFAGIDEARFKRQVIPGDQLVFEVELLTSR
CHHHHHHHHHHHHCEEEEECCCCCCCCCEEEEECCCHHHHHHHCCCCCCEEEEEEEECCC
RGIGKFNAVAKVDGQVAVEAVIMCAKRVV
CCCCCCCCEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDVQLPIEAKDIQKLIPHRYPFLQLDRITAFEPMKTLTAIKNVTINEPQFQGHFPDLPVM
CCCCCCCCHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PGVLIIEAMAQACGTLAILSEGGRKENEFFFFAGIDEARFKRQVIPGDQLVFEVELLTSR
CHHHHHHHHHHHHCEEEEECCCCCCCCCEEEEECCCHHHHHHHCCCCCCEEEEEEEECCC
RGIGKFNAVAKVDGQVAVEAVIMCAKRVV
CCCCCCCCEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA