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The map label for this gene is glu [H]

Identifier: 161870720

GI number: 161870720

Start: 1840581

End: 1841468

Strand: Direct

Name: glu [H]

Synonym: NMCC_1793

Alternate gene names: 161870720

Gene position: 1840581-1841468 (Clockwise)

Preceding gene: 161870719

Following gene: 161870728

Centisome position: 85.47

GC content: 62.84

Gene sequence:

>888_bases
ATGTACACAGGACGTTTCGCCCCCAGCCCGACCGGGCTGCTCCACATCGGCTCGCTGCTGACCGCCGCCGCTTCCTATGC
CGATGCACGCTCAAACGGCGGCAAATGGCTGGTCCGCATGGAAGACCTCGATCCGCCGCGCGAAATGCCGGGGGCGGCAA
GCCATATCCTGCACACGCTTGAGGCATTCGGATTCGAGTGGGACGGAGAAGTCGCCTATCAGAGCCGCCGTTACGCCCTG
TATGAAGAAACCCTATGCCGTCTGAAAACCGCCGGACTGGTCTATCCCTGCCATTGCAGCCGCAAAGACTGGCAGGCTGC
GGCAAGGCGGGGCGCAGACGGGTTCGTCTATAACGGACGTTGCCGCCACCCCGGCCAACGCCCTGCACCGCAAGGCAAAC
AGCCGGCGTGGCGCATCCGCGTCCCCGACCGCGACATCGGCTTTTCAGACGGCATCGTCGGCGGTTACGCCCAAAACCTC
GCCCGCGACATCGGCGATTTCGTCCTGCTTCGTGCAGACGGTTACTGGGCATACCAGCTCGCCGTCGTTGCCGACGATGC
CGAACAGGGCGTTACCCACATCGTCCGCGGGCAAGACCTGCTTGTTTCCACGCCGCGCCAAATCTATTTGCAGCAGTGTT
TGGGCGTTCCGACACCGCAATATGCCCACCTGCCGCTGCTGACCAACGCACAAGGGCAGAAATGGTCGAAACAGACGCTC
GCCCCCGCATTGGATTTAAACCGCCGCGAACAACTCCTCCGCCAAGTGTTCCGTTACCTCAACCTGCCCGAAGCACCGGA
AACCGACCGCCCTGCCGAACTGCTCGACTGGGCGGTGGCACACTGGGATATGGACAAAGTGCCGAAACACGCCGTTACCC
CCCCCTGA

Upstream 100 bases:

>100_bases
CTATATGATTTAACCTTACTTGAAGAACCCGGGATGGAACTGAATAAAGATGAGATAATGGCTTTGATTAATAGTCTTAA
ATAAAGGGGCCGTACCGGAT

Downstream 100 bases:

>100_bases
ACACCGCCCGACAAACGCACAAATGCCGTCTGAAACCTTCAGACGGCATTTCACACATACAGCCCCGCCCTATTCACGCG
TATTTGCCCACTCAACCTCT

Product: glutamyl-Q tRNA(Asp) synthetase

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MYTGRFAPSPTGLLHIGSLLTAAASYADARSNGGKWLVRMEDLDPPREMPGAASHILHTLEAFGFEWDGEVAYQSRRYAL
YEETLCRLKTAGLVYPCHCSRKDWQAAARRGADGFVYNGRCRHPGQRPAPQGKQPAWRIRVPDRDIGFSDGIVGGYAQNL
ARDIGDFVLLRADGYWAYQLAVVADDAEQGVTHIVRGQDLLVSTPRQIYLQQCLGVPTPQYAHLPLLTNAQGQKWSKQTL
APALDLNRREQLLRQVFRYLNLPEAPETDRPAELLDWAVAHWDMDKVPKHAVTPP

Sequences:

>Translated_295_residues
MYTGRFAPSPTGLLHIGSLLTAAASYADARSNGGKWLVRMEDLDPPREMPGAASHILHTLEAFGFEWDGEVAYQSRRYAL
YEETLCRLKTAGLVYPCHCSRKDWQAAARRGADGFVYNGRCRHPGQRPAPQGKQPAWRIRVPDRDIGFSDGIVGGYAQNL
ARDIGDFVLLRADGYWAYQLAVVADDAEQGVTHIVRGQDLLVSTPRQIYLQQCLGVPTPQYAHLPLLTNAQGQKWSKQTL
APALDLNRREQLLRQVFRYLNLPEAPETDRPAELLDWAVAHWDMDKVPKHAVTPP
>Mature_295_residues
MYTGRFAPSPTGLLHIGSLLTAAASYADARSNGGKWLVRMEDLDPPREMPGAASHILHTLEAFGFEWDGEVAYQSRRYAL
YEETLCRLKTAGLVYPCHCSRKDWQAAARRGADGFVYNGRCRHPGQRPAPQGKQPAWRIRVPDRDIGFSDGIVGGYAQNL
ARDIGDFVLLRADGYWAYQLAVVADDAEQGVTHIVRGQDLLVSTPRQIYLQQCLGVPTPQYAHLPLLTNAQGQKWSKQTL
APALDLNRREQLLRQVFRYLNLPEAPETDRPAELLDWAVAHWDMDKVPKHAVTPP

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=249, Percent_Identity=37.7510040160643, Blast_Score=149, Evalue=3e-36,
Organism=Escherichia coli, GI226510925, Length=296, Percent_Identity=45.6081081081081, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1788743, Length=237, Percent_Identity=34.1772151898734, Blast_Score=147, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI71993394, Length=250, Percent_Identity=32.8, Blast_Score=123, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6324540, Length=250, Percent_Identity=34, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24665321, Length=249, Percent_Identity=34.136546184739, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 33026; Mature: 33026

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTGRFAPSPTGLLHIGSLLTAAASYADARSNGGKWLVRMEDLDPPREMPGAASHILHTL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHCCCHHHHHHHHH
EAFGFEWDGEVAYQSRRYALYEETLCRLKTAGLVYPCHCSRKDWQAAARRGADGFVYNGR
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCCCEECCC
CRHPGQRPAPQGKQPAWRIRVPDRDIGFSDGIVGGYAQNLARDIGDFVLLRADGYWAYQL
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCEEEEE
AVVADDAEQGVTHIVRGQDLLVSTPRQIYLQQCLGVPTPQYAHLPLLTNAQGQKWSKQTL
EEEECCHHHHHHHHHCCCCCEECCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHH
APALDLNRREQLLRQVFRYLNLPEAPETDRPAELLDWAVAHWDMDKVPKHAVTPP
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCC
>Mature Secondary Structure
MYTGRFAPSPTGLLHIGSLLTAAASYADARSNGGKWLVRMEDLDPPREMPGAASHILHTL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHCCCHHHHHHHHH
EAFGFEWDGEVAYQSRRYALYEETLCRLKTAGLVYPCHCSRKDWQAAARRGADGFVYNGR
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCCCEECCC
CRHPGQRPAPQGKQPAWRIRVPDRDIGFSDGIVGGYAQNLARDIGDFVLLRADGYWAYQL
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCEEEEE
AVVADDAEQGVTHIVRGQDLLVSTPRQIYLQQCLGVPTPQYAHLPLLTNAQGQKWSKQTL
EEEECCHHHHHHHHHCCCCCEECCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHH
APALDLNRREQLLRQVFRYLNLPEAPETDRPAELLDWAVAHWDMDKVPKHAVTPP
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA