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The map label for this gene is pheA [H]

Identifier: 161870628

GI number: 161870628

Start: 1733269

End: 1734357

Strand: Reverse

Name: pheA [H]

Synonym: NMCC_1697

Alternate gene names: 161870628

Gene position: 1734357-1733269 (Counterclockwise)

Preceding gene: 161870629

Following gene: 161870627

Centisome position: 80.54

GC content: 60.15

Gene sequence:

>1089_bases
ATGTCCCAAACTATCGACGAACTCCTCCTTCCCCACCGCAACGCCATCGACACCATCGATGCCGAAATCCTGCGCCTGCT
CAACGAACGCGCGCAACACGCCCACGCCATCGGCGAACTGAAAGGCACGGGCGCAGTATACCGTCCGGAGCGCGAGGTCG
CCGTGTTGCGCCGCATTCAGGATTTGAACAAAGGCCCGCTGCCCGACGAATCGGTAGCACGCCTGTTTCGGGAAGTGATG
AGCGAGTGTCTCGCCGTCGAACGCCCGCTGACCATCGCCTATCTGGGGCCGCAGGGCACGTTTACCCAGCAGGCGGCGAT
TAAGCATTTCGGACACGCCGCGCACACCATGGCGTGTCCGACCATAGACAACTGCTTCAAGCAGGTTGAAACCCGTCAGG
CAGACTATCTGGTCGCCCCCGTGGAAAACTCGACCGAAGGCTCGGTCGGGCGCACGTTGGATTTGCTTGCCGTTACCGCG
TTGCAGGCGTGCGGCGAAGTCGTTTTGCGCATCCACCACAACCTTTTGCGTAAAAACAACGGCAGCACCGAAGGCATTGC
CAAAGTCTTTTCCCACGCGCAGGCGTTGGCGCAGTGCAACGACTGGTTGGGCAGACACCTGCCCAACGCCGAACGGATTG
CTGTGTCCAGCAATGCCGAAGCCGCAAGGCTGGTTGCCGAATCGGACGACGGTACGGTTGCCGCCATCGCCGGACGCACG
GCGGCGGAAATCTACGGACTCGATATGGTTGCCGAGTGCATCGAAGACGAACCGAACAACACCACGCGCTTCTTGGTGAT
GGGACATCACGAAACCGGTGCAAGCAGCAGCGACAAGACTTCGCTGGCCGTTTCCGCGCCCAACCGCGCCGGTGCGGTTG
CCTCGCTGCTGCAACCGCTGACCGAGTCGGGTATTTCCATGACCAAGTTTGAGAGCCGTCCGAGCAAATCCGTTTTGTGG
GAATACCTGTTCTTCATCGACATCGAAGGACACCGCCGGGATGCACAGATTCAGACGGCATTGGAACGCTTGGGCGAACG
CGCTTCGTTCGTCAAAGTCATCGGTTCGTACCCGACCGCCGTTTTGTAG

Upstream 100 bases:

>100_bases
ACGAACAGAGCGAATACCTTTAACGGAAAATGCCGTCTGAAACCGTTTCAGACGGCATTTGATGTTAGAATGCACGATAA
ATTACTGTTCAGGCGAAATT

Downstream 100 bases:

>100_bases
CGGCGGCAGCGTTCAGACGGCATTTCAGGCATGATGTCCGAACACCGAGTCAACCACGAACCCGTCTTCCTGTTGGCTTC
CTCGCCATGGCGCGAAAGCA

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSQTIDELLLPHRNAIDTIDAEILRLLNERAQHAHAIGELKGTGAVYRPEREVAVLRRIQDLNKGPLPDESVARLFREVM
SECLAVERPLTIAYLGPQGTFTQQAAIKHFGHAAHTMACPTIDNCFKQVETRQADYLVAPVENSTEGSVGRTLDLLAVTA
LQACGEVVLRIHHNLLRKNNGSTEGIAKVFSHAQALAQCNDWLGRHLPNAERIAVSSNAEAARLVAESDDGTVAAIAGRT
AAEIYGLDMVAECIEDEPNNTTRFLVMGHHETGASSSDKTSLAVSAPNRAGAVASLLQPLTESGISMTKFESRPSKSVLW
EYLFFIDIEGHRRDAQIQTALERLGERASFVKVIGSYPTAVL

Sequences:

>Translated_362_residues
MSQTIDELLLPHRNAIDTIDAEILRLLNERAQHAHAIGELKGTGAVYRPEREVAVLRRIQDLNKGPLPDESVARLFREVM
SECLAVERPLTIAYLGPQGTFTQQAAIKHFGHAAHTMACPTIDNCFKQVETRQADYLVAPVENSTEGSVGRTLDLLAVTA
LQACGEVVLRIHHNLLRKNNGSTEGIAKVFSHAQALAQCNDWLGRHLPNAERIAVSSNAEAARLVAESDDGTVAAIAGRT
AAEIYGLDMVAECIEDEPNNTTRFLVMGHHETGASSSDKTSLAVSAPNRAGAVASLLQPLTESGISMTKFESRPSKSVLW
EYLFFIDIEGHRRDAQIQTALERLGERASFVKVIGSYPTAVL
>Mature_361_residues
SQTIDELLLPHRNAIDTIDAEILRLLNERAQHAHAIGELKGTGAVYRPEREVAVLRRIQDLNKGPLPDESVARLFREVMS
ECLAVERPLTIAYLGPQGTFTQQAAIKHFGHAAHTMACPTIDNCFKQVETRQADYLVAPVENSTEGSVGRTLDLLAVTAL
QACGEVVLRIHHNLLRKNNGSTEGIAKVFSHAQALAQCNDWLGRHLPNAERIAVSSNAEAARLVAESDDGTVAAIAGRTA
AEIYGLDMVAECIEDEPNNTTRFLVMGHHETGASSSDKTSLAVSAPNRAGAVASLLQPLTESGISMTKFESRPSKSVLWE
YLFFIDIEGHRRDAQIQTALERLGERASFVKVIGSYPTAVL

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=375, Percent_Identity=32, Blast_Score=179, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 39392; Mature: 39261

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTIDELLLPHRNAIDTIDAEILRLLNERAQHAHAIGELKGTGAVYRPEREVAVLRRIQ
CCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
DLNKGPLPDESVARLFREVMSECLAVERPLTIAYLGPQGTFTQQAAIKHFGHAAHTMACP
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHCCC
TIDNCFKQVETRQADYLVAPVENSTEGSVGRTLDLLAVTALQACGEVVLRIHHNLLRKNN
CHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GSTEGIAKVFSHAQALAQCNDWLGRHLPNAERIAVSSNAEAARLVAESDDGTVAAIAGRT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHEEEECCCCCEEEECCCH
AAEIYGLDMVAECIEDEPNNTTRFLVMGHHETGASSSDKTSLAVSAPNRAGAVASLLQPL
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
TESGISMTKFESRPSKSVLWEYLFFIDIEGHRRDAQIQTALERLGERASFVKVIGSYPTA
HHCCCEEEHHCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VL
CC
>Mature Secondary Structure 
SQTIDELLLPHRNAIDTIDAEILRLLNERAQHAHAIGELKGTGAVYRPEREVAVLRRIQ
CCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
DLNKGPLPDESVARLFREVMSECLAVERPLTIAYLGPQGTFTQQAAIKHFGHAAHTMACP
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHCCC
TIDNCFKQVETRQADYLVAPVENSTEGSVGRTLDLLAVTALQACGEVVLRIHHNLLRKNN
CHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GSTEGIAKVFSHAQALAQCNDWLGRHLPNAERIAVSSNAEAARLVAESDDGTVAAIAGRT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHEEEECCCCCEEEECCCH
AAEIYGLDMVAECIEDEPNNTTRFLVMGHHETGASSSDKTSLAVSAPNRAGAVASLLQPL
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
TESGISMTKFESRPSKSVLWEYLFFIDIEGHRRDAQIQTALERLGERASFVKVIGSYPTA
HHCCCEEEHHCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094619 [H]