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The map label for this gene is speA [H]

Identifier: 161870605

GI number: 161870605

Start: 1703906

End: 1705798

Strand: Reverse

Name: speA [H]

Synonym: NMCC_1674

Alternate gene names: 161870605

Gene position: 1705798-1703906 (Counterclockwise)

Preceding gene: 161870606

Following gene: 161871035

Centisome position: 79.21

GC content: 49.6

Gene sequence:

>1893_bases
ATGCCTATCCTTACCATCCGTGAAGTGTGCAACATTAATCATTGGGGCATAGGTTATTATGATGTTGACGATTCCGGCGA
AATCATCGTCCGCCCCAATCCCTCGCAACACAATCAAACTGTTTCACTGCAAAAACTGACTGAAGCCGTGCAACAAAAAC
ATCAGGCGCGCCTGCCTGTTTTGTTTTGTTTTCCGCAAATCCTCGAACACCGCCTCCGCGACATTAACCGCGCCTTTCAG
ACGGCACGGGAAGAGTGCGGCTATAAGGGCGGTTATTGTTTGGTTTACCCTATCAAGGTCAACCAACACCGCCGCGTCAT
CGAATCGCTTATGTCAAGCGGACAACCGCATGGTTTGGAAGCTGGTTCTAAAGCCGAACTGATGGCGGTTTTGGCACACG
CCGGCACCCGGCAAACATTAATCGTCTGCAACGGCTATAAAGACCGTGAATATATCCGTTTCGCCTTGATGGGCGAAAAA
CTGGGGCATCAGGTTTATTTGGTGATTGAGAAGCTGTCCGAAATACAAATGGTATTGGAAGAGGCGGAAAAACTCGGCAT
CAAGCCCCGTTTGGGTGTGCGCGCCAGACTGGCTTCCCAAGGTTCGGGAAAATGGCAGTCTTCGGGTGGGGAAAAATCAA
AATTCGGCTTGTCGGCTTCCCAAGTTTTGCAACTGGTCGATATTTTGAAACAAAAAAACAGGCTGGACTGCCTGCAGCTT
TTGCATTTCCATTTAGGCTCGCAGCTTGGGAACATCCGTGATGTTGCCACAGGTGTACACGAATCGGCTCGGTTTTATGT
TGAGTTGCACAAACTGGGGGTAAATATCCGCTGTTTTGATGTAGGCGGCGGGCTTGGCGTGGATTACGAAGGAAACCGCA
CACAATCGGATTGTTCCGTTAATTACAGCCTCAACGAATATGCCTCCACAGTCGTATGGGGCATCAGCCAGGCTTGTCTC
GAACACGGGCTGCCGCATCCGACAATCATTACCGAGAGCGGGCGCGGCATTACCGCACATCACGCCGTTTTGGTTGCTAA
TGTTATAGGCGTTGAACGTTACAAACCGCGCCGGCTGGATGCGCCATCGCCCGAAGCACCGCGTGTGTTGCACAGTATGT
GGGAAACTTGGACGGATATTTCCGCCTCGCGGGAAAAACGTTCCTTACGCAGCTGGATACACGAAGGGCAGTTTGATCTT
GCCGATGTGCATAATCAGTATAATGTCGGGCTGTTGAGTTTGGCGCAACGTGCGTGGGCGGAGCAACTGTATTTAAATAT
CTGTCATGAAGTCGGCGAATTGTTTAATGAAAAACACCGGTCTCACCGAACCATTATTGACGAATTGCAAGAACGTTTTG
CCGATAAGCTGTATGTCAATTTCTCACTCTTCCAATCTTTGCCCGATGCTTGGGGCATAGATCAACTTTTCCCTGTTTGT
CCCATTACCGGTTTGAATGAACCGATTGCGCGCCGCGCCGTGTTGTTGGACATTACCTGCGATTCAGACGGTACGATTGA
CCACTACATCGACGGAGACGGCATCGCCGGTACGATGCCTATGCCTGATTATCCCGAAGAAGAGCCGCCGCTTTTAGGCT
TTTTTATGGTGGGAGCATATCAGGAAATACTCGGCAATATGCACAATCTTTTCGGCGACACTGCCACTGCCGATGTTGTT
GTAGGGGAAGACGGACAATTTACCGTCATCGATTACGATGAAGGAAACACCGTTGCCGATATGCTCGAATACGTTTATCA
AGATCCGAAAGAGCTGATGAAACGCTATCGCGAACAAATCGAACATTCAGACCTTCCTGCCTCGCAGGCTATGTCTTTCT
TAAAAGAACTCGAAGCGGGGCTTAATGGTTATACCTATTTGGAAGACGAATAG

Upstream 100 bases:

>100_bases
CATCAGGTATGAGGCAGGCTTTTCTTATTAAAAAAATGACATTTCACGCTGATTTGTTATAATCATTCCTTTTCAACACG
ACAGACGGAGCAGGTTTATT

Downstream 100 bases:

>100_bases
ACGCATCAAGGCATCGGATATGTCGTCTGAAGCCCGATTTTCTTACTCAAACACCAATCATCACGACCGATTGAAACCAA
TTACAAGGAATCATTACGAT

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 630; Mature: 629

Protein sequence:

>630_residues
MPILTIREVCNINHWGIGYYDVDDSGEIIVRPNPSQHNQTVSLQKLTEAVQQKHQARLPVLFCFPQILEHRLRDINRAFQ
TAREECGYKGGYCLVYPIKVNQHRRVIESLMSSGQPHGLEAGSKAELMAVLAHAGTRQTLIVCNGYKDREYIRFALMGEK
LGHQVYLVIEKLSEIQMVLEEAEKLGIKPRLGVRARLASQGSGKWQSSGGEKSKFGLSASQVLQLVDILKQKNRLDCLQL
LHFHLGSQLGNIRDVATGVHESARFYVELHKLGVNIRCFDVGGGLGVDYEGNRTQSDCSVNYSLNEYASTVVWGISQACL
EHGLPHPTIITESGRGITAHHAVLVANVIGVERYKPRRLDAPSPEAPRVLHSMWETWTDISASREKRSLRSWIHEGQFDL
ADVHNQYNVGLLSLAQRAWAEQLYLNICHEVGELFNEKHRSHRTIIDELQERFADKLYVNFSLFQSLPDAWGIDQLFPVC
PITGLNEPIARRAVLLDITCDSDGTIDHYIDGDGIAGTMPMPDYPEEEPPLLGFFMVGAYQEILGNMHNLFGDTATADVV
VGEDGQFTVIDYDEGNTVADMLEYVYQDPKELMKRYREQIEHSDLPASQAMSFLKELEAGLNGYTYLEDE

Sequences:

>Translated_630_residues
MPILTIREVCNINHWGIGYYDVDDSGEIIVRPNPSQHNQTVSLQKLTEAVQQKHQARLPVLFCFPQILEHRLRDINRAFQ
TAREECGYKGGYCLVYPIKVNQHRRVIESLMSSGQPHGLEAGSKAELMAVLAHAGTRQTLIVCNGYKDREYIRFALMGEK
LGHQVYLVIEKLSEIQMVLEEAEKLGIKPRLGVRARLASQGSGKWQSSGGEKSKFGLSASQVLQLVDILKQKNRLDCLQL
LHFHLGSQLGNIRDVATGVHESARFYVELHKLGVNIRCFDVGGGLGVDYEGNRTQSDCSVNYSLNEYASTVVWGISQACL
EHGLPHPTIITESGRGITAHHAVLVANVIGVERYKPRRLDAPSPEAPRVLHSMWETWTDISASREKRSLRSWIHEGQFDL
ADVHNQYNVGLLSLAQRAWAEQLYLNICHEVGELFNEKHRSHRTIIDELQERFADKLYVNFSLFQSLPDAWGIDQLFPVC
PITGLNEPIARRAVLLDITCDSDGTIDHYIDGDGIAGTMPMPDYPEEEPPLLGFFMVGAYQEILGNMHNLFGDTATADVV
VGEDGQFTVIDYDEGNTVADMLEYVYQDPKELMKRYREQIEHSDLPASQAMSFLKELEAGLNGYTYLEDE
>Mature_629_residues
PILTIREVCNINHWGIGYYDVDDSGEIIVRPNPSQHNQTVSLQKLTEAVQQKHQARLPVLFCFPQILEHRLRDINRAFQT
AREECGYKGGYCLVYPIKVNQHRRVIESLMSSGQPHGLEAGSKAELMAVLAHAGTRQTLIVCNGYKDREYIRFALMGEKL
GHQVYLVIEKLSEIQMVLEEAEKLGIKPRLGVRARLASQGSGKWQSSGGEKSKFGLSASQVLQLVDILKQKNRLDCLQLL
HFHLGSQLGNIRDVATGVHESARFYVELHKLGVNIRCFDVGGGLGVDYEGNRTQSDCSVNYSLNEYASTVVWGISQACLE
HGLPHPTIITESGRGITAHHAVLVANVIGVERYKPRRLDAPSPEAPRVLHSMWETWTDISASREKRSLRSWIHEGQFDLA
DVHNQYNVGLLSLAQRAWAEQLYLNICHEVGELFNEKHRSHRTIIDELQERFADKLYVNFSLFQSLPDAWGIDQLFPVCP
ITGLNEPIARRAVLLDITCDSDGTIDHYIDGDGIAGTMPMPDYPEEEPPLLGFFMVGAYQEILGNMHNLFGDTATADVVV
GEDGQFTVIDYDEGNTVADMLEYVYQDPKELMKRYREQIEHSDLPASQAMSFLKELEAGLNGYTYLEDE

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=620, Percent_Identity=68.7096774193548, Blast_Score=893, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 70906; Mature: 70775

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPILTIREVCNINHWGIGYYDVDDSGEIIVRPNPSQHNQTVSLQKLTEAVQQKHQARLPV
CCCEEHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCCCEEHHHHHHHHHHHHHHCCCCH
LFCFPQILEHRLRDINRAFQTAREECGYKGGYCLVYPIKVNQHRRVIESLMSSGQPHGLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCCCCC
AGSKAELMAVLAHAGTRQTLIVCNGYKDREYIRFALMGEKLGHQVYLVIEKLSEIQMVLE
CCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EAEKLGIKPRLGVRARLASQGSGKWQSSGGEKSKFGLSASQVLQLVDILKQKNRLDCLQL
HHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCHHHHHHH
LHFHLGSQLGNIRDVATGVHESARFYVELHKLGVNIRCFDVGGGLGVDYEGNRTQSDCSV
HHHHHHHHCCCHHHHHHHHHHHHHHEEEHHHHCCEEEEEECCCCCCCCCCCCCCCCCCEE
NYSLNEYASTVVWGISQACLEHGLPHPTIITESGRGITAHHAVLVANVIGVERYKPRRLD
ECCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCC
APSPEAPRVLHSMWETWTDISASREKRSLRSWIHEGQFDLADVHNQYNVGLLSLAQRAWA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHH
EQLYLNICHEVGELFNEKHRSHRTIIDELQERFADKLYVNFSLFQSLPDAWGIDQLFPVC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHCCCCCCCHHHHCCCC
PITGLNEPIARRAVLLDITCDSDGTIDHYIDGDGIAGTMPMPDYPEEEPPLLGFFMVGAY
CCCCCCCHHHCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEHHHHHHHH
QEILGNMHNLFGDTATADVVVGEDGQFTVIDYDEGNTVADMLEYVYQDPKELMKRYREQI
HHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHH
EHSDLPASQAMSFLKELEAGLNGYTYLEDE
HCCCCCHHHHHHHHHHHHHCCCCCEEECCC
>Mature Secondary Structure 
PILTIREVCNINHWGIGYYDVDDSGEIIVRPNPSQHNQTVSLQKLTEAVQQKHQARLPV
CCEEHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCCCEEHHHHHHHHHHHHHHCCCCH
LFCFPQILEHRLRDINRAFQTAREECGYKGGYCLVYPIKVNQHRRVIESLMSSGQPHGLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCCCCC
AGSKAELMAVLAHAGTRQTLIVCNGYKDREYIRFALMGEKLGHQVYLVIEKLSEIQMVLE
CCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EAEKLGIKPRLGVRARLASQGSGKWQSSGGEKSKFGLSASQVLQLVDILKQKNRLDCLQL
HHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCHHHHHHH
LHFHLGSQLGNIRDVATGVHESARFYVELHKLGVNIRCFDVGGGLGVDYEGNRTQSDCSV
HHHHHHHHCCCHHHHHHHHHHHHHHEEEHHHHCCEEEEEECCCCCCCCCCCCCCCCCCEE
NYSLNEYASTVVWGISQACLEHGLPHPTIITESGRGITAHHAVLVANVIGVERYKPRRLD
ECCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCC
APSPEAPRVLHSMWETWTDISASREKRSLRSWIHEGQFDLADVHNQYNVGLLSLAQRAWA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHH
EQLYLNICHEVGELFNEKHRSHRTIIDELQERFADKLYVNFSLFQSLPDAWGIDQLFPVC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHCCCCCCCHHHHCCCC
PITGLNEPIARRAVLLDITCDSDGTIDHYIDGDGIAGTMPMPDYPEEEPPLLGFFMVGAY
CCCCCCCHHHCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEHHHHHHHH
QEILGNMHNLFGDTATADVVVGEDGQFTVIDYDEGNTVADMLEYVYQDPKELMKRYREQI
HHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHH
EHSDLPASQAMSFLKELEAGLNGYTYLEDE
HCCCCCHHHHHHHHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]