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The map label for this gene is speB [H]

Identifier: 161871035

GI number: 161871035

Start: 1702884

End: 1703807

Strand: Reverse

Name: speB [H]

Synonym: NMCC_1673

Alternate gene names: 161871035

Gene position: 1703807-1702884 (Counterclockwise)

Preceding gene: 161870605

Following gene: 161870604

Centisome position: 79.12

GC content: 53.14

Gene sequence:

>924_bases
ATGCAATACAGCACACTGGCAGGACAAACCGACAACTCCCTCGTTTCCAATAATTTCGGGTTTTTGCGCCTGCCGCTTAA
TTTTATGCCGTATGAAAGTCATGCCGATTGGGTTATTACCGGCGTGCCTTATGATATGGCGGTTTCAGGGCGTTCCGGCG
CGCGTTTCGGTCCTGAAGCCATCCGGCGCGCCTCCGTCAACCTCGCTTGGGAGCACCGCAGGTTTCCATGGACATTTGAT
GTGCGCGAACGCCTGAACATTATTGATTGCGGCGACTTGGTTTTTTCTTTTGGCGACAGCAGGGATTTTGTCGAAAAAAT
GGAAGCGCACGCCGGCAAATTACTTTCTTCCGGCAAACGCTGTTTGAGTTTGGGCGGCGACCATTTCATTACCCTCCCGT
TGTTGCGCGCCCACGCCCGCTATTTCGGCAAACTCGCACTGATTCATTTTGACGCGCACACCGACACCTACGACAACGGC
AGCGAATACGACCACGGTACGATGTTCTATACCGCCCCCAAGGAAGGCCTCATCGACCCGTCCCGTTCCGTACAAATCGG
CATACGTACCGAACACAGTAAAAAATTGCCTTTTACTGTGTTGACCGCCCCCCAAGTTAATGAAGACAGTGTTGAAGAGA
CCGTCCGTAAAATCAAAGAAACCGTCGGCAATATGCCCGTTTACCTGACTTTCGACATAGACTGCCTCGACCCGTCGTTC
GCCCCCGGGACCGGTACGCCCGTATGCGGCGGCTTGAGCAGCGACAGGGCATTAAAAATCCTACGTGGGCTGACGGATCT
CGACATCGTCGGTATGGATGTTGTAGAAGTTGCCCCCTCTTACGACCAATCCGACATTACCGCTTTGGCCGGCGCCACAA
TTGCCTTGGAAATGCTTTACCTTCAAGGTGCGAAAAAGGACTGA

Upstream 100 bases:

>100_bases
AGACGCATCAAGGCATCGGATATGTCGTCTGAAGCCCGATTTTCTTACTCAAACACCAATCATCACGACCGATTGAAACC
AATTACAAGGAATCATTACG

Downstream 100 bases:

>100_bases
ACGTCCGGCATCCCCCGGGTTTTCGCCGTGCCGTTCAAACGGCGTATTCAGTCTAATGAAAATTCAAATACTGAAACAAA
AGTTGCCCGGAGCCGCATAT

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MQYSTLAGQTDNSLVSNNFGFLRLPLNFMPYESHADWVITGVPYDMAVSGRSGARFGPEAIRRASVNLAWEHRRFPWTFD
VRERLNIIDCGDLVFSFGDSRDFVEKMEAHAGKLLSSGKRCLSLGGDHFITLPLLRAHARYFGKLALIHFDAHTDTYDNG
SEYDHGTMFYTAPKEGLIDPSRSVQIGIRTEHSKKLPFTVLTAPQVNEDSVEETVRKIKETVGNMPVYLTFDIDCLDPSF
APGTGTPVCGGLSSDRALKILRGLTDLDIVGMDVVEVAPSYDQSDITALAGATIALEMLYLQGAKKD

Sequences:

>Translated_307_residues
MQYSTLAGQTDNSLVSNNFGFLRLPLNFMPYESHADWVITGVPYDMAVSGRSGARFGPEAIRRASVNLAWEHRRFPWTFD
VRERLNIIDCGDLVFSFGDSRDFVEKMEAHAGKLLSSGKRCLSLGGDHFITLPLLRAHARYFGKLALIHFDAHTDTYDNG
SEYDHGTMFYTAPKEGLIDPSRSVQIGIRTEHSKKLPFTVLTAPQVNEDSVEETVRKIKETVGNMPVYLTFDIDCLDPSF
APGTGTPVCGGLSSDRALKILRGLTDLDIVGMDVVEVAPSYDQSDITALAGATIALEMLYLQGAKKD
>Mature_307_residues
MQYSTLAGQTDNSLVSNNFGFLRLPLNFMPYESHADWVITGVPYDMAVSGRSGARFGPEAIRRASVNLAWEHRRFPWTFD
VRERLNIIDCGDLVFSFGDSRDFVEKMEAHAGKLLSSGKRCLSLGGDHFITLPLLRAHARYFGKLALIHFDAHTDTYDNG
SEYDHGTMFYTAPKEGLIDPSRSVQIGIRTEHSKKLPFTVLTAPQVNEDSVEETVRKIKETVGNMPVYLTFDIDCLDPSF
APGTGTPVCGGLSSDRALKILRGLTDLDIVGMDVVEVAPSYDQSDITALAGATIALEMLYLQGAKKD

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=290, Percent_Identity=39.3103448275862, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI10947139, Length=306, Percent_Identity=27.4509803921569, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4502215, Length=308, Percent_Identity=25.3246753246753, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1789306, Length=303, Percent_Identity=74.2574257425743, Blast_Score=472, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 33920; Mature: 33920

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYSTLAGQTDNSLVSNNFGFLRLPLNFMPYESHADWVITGVPYDMAVSGRSGARFGPEA
CCCCCCCCCCCCCCHHCCCCEEEECCEECCCCCCCCEEEECCCCEEEECCCCCCCCCHHH
IRRASVNLAWEHRRFPWTFDVRERLNIIDCGDLVFSFGDSRDFVEKMEAHAGKLLSSGKR
HHHHCCCEEEECCCCCEEEEHHHCCCEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCH
CLSLGGDHFITLPLLRAHARYFGKLALIHFDAHTDTYDNGSEYDHGTMFYTAPKEGLIDP
HHHCCCCCEEEHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCC
SRSVQIGIRTEHSKKLPFTVLTAPQVNEDSVEETVRKIKETVGNMPVYLTFDIDCLDPSF
CCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCC
APGTGTPVCGGLSSDRALKILRGLTDLDIVGMDVVEVAPSYDQSDITALAGATIALEMLY
CCCCCCCEECCCCCHHHHHHHHCCCCCEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LQGAKKD
HCCCCCC
>Mature Secondary Structure
MQYSTLAGQTDNSLVSNNFGFLRLPLNFMPYESHADWVITGVPYDMAVSGRSGARFGPEA
CCCCCCCCCCCCCCHHCCCCEEEECCEECCCCCCCCEEEECCCCEEEECCCCCCCCCHHH
IRRASVNLAWEHRRFPWTFDVRERLNIIDCGDLVFSFGDSRDFVEKMEAHAGKLLSSGKR
HHHHCCCEEEECCCCCEEEEHHHCCCEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCH
CLSLGGDHFITLPLLRAHARYFGKLALIHFDAHTDTYDNGSEYDHGTMFYTAPKEGLIDP
HHHCCCCCEEEHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCC
SRSVQIGIRTEHSKKLPFTVLTAPQVNEDSVEETVRKIKETVGNMPVYLTFDIDCLDPSF
CCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCC
APGTGTPVCGGLSSDRALKILRGLTDLDIVGMDVVEVAPSYDQSDITALAGATIALEMLY
CCCCCCCEECCCCCHHHHHHHHCCCCCEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LQGAKKD
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA