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The map label for this gene is mtrF [H]

Identifier: 161870565

GI number: 161870565

Start: 1661783

End: 1663351

Strand: Direct

Name: mtrF [H]

Synonym: NMCC_1631

Alternate gene names: 161870565

Gene position: 1661783-1663351 (Clockwise)

Preceding gene: 161870563

Following gene: 161870573

Centisome position: 77.17

GC content: 48.25

Gene sequence:

>1569_bases
ATGAGTCAAACCGATACGCAACGGGACGGACGATTTTTACGCACAGTCGAATGGCTGGGCAATATGTTGCCGCACCCGGT
TACGCTTTTTATTATTTTCATTGTGTTATTGCTGATTGCCTCTGCCGCCGGTGCGTATTTCGAACTATCCGTCCCCGATC
CGCGCCCTGTTGGTGCGAAAGGACGTGCCGATGACGGTTTGATTCACGTTGTCAGCCTGCTCGATGCTGACGGTTTGATC
AAAATCCTGACGCATACCGTTAAAAATTTCACCGGTTTCGCGCCGTTGGGAACGGTGTTGGTTTCTTTATTGGGCGTGGG
GATTGCGGAAAAATCGGGCTTGATTTCCGCATTAATGCGCTTATTGCTCACAAAATCTCCACGCAAACTCACTACTTTTA
TGGTTGTTTTTACAGGGATTTTATCTAATACCGCTTCTGAATTGGGCTATGTCGTCCTAATCCCTTTGTCCGCCATCATC
TTTCATTCCCTCGGCCGCCATCCGCTTGCCGGTCTGGCTGCGGCTTTCGCCGGCGTTTCGGGCGGTTATTCGGCCAATCT
GTTCTTAGGCACAATCGATCCGCTCTTGGCAGGCATCACCCAACAGGCGGCGCAAATCATCCATCCCGACTACGTCGTAG
GCCCTGAAGCCAACTGGTTTTTTATGGTAGCCAGTACGTTTGTGATTGCTTTGATTGGTTATTTTGTTACTGAAAAAATC
GTCGAACCGCAATTGGGCCCTTATCAATCAGATTTGTCACAAGAAGAAAAAGACATTCGACATTCCAATGAAATCACGCC
TTTGGAATATAAAGGATTAATTTGGGCTGGCGTGGTGTTTGTTGCCTTATCCGCCCTATTGGCTTGGAGCATCGTCCCTG
CCGACGGTATTTTGCGTCATCCTGAAACAGGATTGGTTTCCGGTTCGCCGTTTTTAAAATCAATTGTTGTTTTTATTTTC
TTGTTGTTTGCACTGCCGGGCATTGTTTATGGCCGGGTAACCCGAAGTTTGCGCGGCGAACAGGAAGTCGTTAATGCGAT
GGCCGAATCGATGAGTACTCTGGGGCTTTATTTGGTCATCATCTTTTTTGCCGCACAGTTTGTCGCATTTTTTAATTGGA
CGAATATTGGGCAATATATTGCCGTTAAAGGGGCGACGTTCTTAAAAGAAGTCGGCTTGGGCGGCAGCGTGTTGTTTATC
GGTTTTATTTTAATTTGTGCTTTTATCAATCTGATGATAGGCTCCGCCTCCGCGCAATGGGCGGTAACTGCGCCGATTTT
CGTCCCTATGCTGATGTTGGCCGGCTACGCGCCCGAAGTCATTCAAGCCGCTTACCGCATCGGTGATTCCGTTACCAATA
TTATTACGCCGATGATGAGTTATTTCGGGCTGATTATGGCGACGGTGATCAAATACAAAAAAGATGCGGGCGTGGGTACG
CTGATTTCTATGATGTTGCCGTATTCCGCTTTCTTCTTGATTGCGTGGATTGCCTTATTCTGCATTTGGGTATTTGTTTT
GGGCCTGCCCGTCGGTCCCGGCGCGCCCACATTCTATCCCGCACCTTAA

Upstream 100 bases:

>100_bases
GGTTATATACATATACGATTATTTTAGTTTGCTTACAAAACACTTCATGTTACATTCAAAAATTTAATGCACTCAATATA
TTTTTTTTAAGGAGAAGCAG

Downstream 100 bases:

>100_bases
ACACGATAAACAAAATGCCGTCTGAAAACCTTTTTGCTGTTTTCAGACGGCATTTGCCTTTCCATCCCGTCAGGCTGCTC
CGGCCCCTTCCCTTTTTTCC

Product: efflux pump component MtrF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MSQTDTQRDGRFLRTVEWLGNMLPHPVTLFIIFIVLLLIASAAGAYFELSVPDPRPVGAKGRADDGLIHVVSLLDADGLI
KILTHTVKNFTGFAPLGTVLVSLLGVGIAEKSGLISALMRLLLTKSPRKLTTFMVVFTGILSNTASELGYVVLIPLSAII
FHSLGRHPLAGLAAAFAGVSGGYSANLFLGTIDPLLAGITQQAAQIIHPDYVVGPEANWFFMVASTFVIALIGYFVTEKI
VEPQLGPYQSDLSQEEKDIRHSNEITPLEYKGLIWAGVVFVALSALLAWSIVPADGILRHPETGLVSGSPFLKSIVVFIF
LLFALPGIVYGRVTRSLRGEQEVVNAMAESMSTLGLYLVIIFFAAQFVAFFNWTNIGQYIAVKGATFLKEVGLGGSVLFI
GFILICAFINLMIGSASAQWAVTAPIFVPMLMLAGYAPEVIQAAYRIGDSVTNIITPMMSYFGLIMATVIKYKKDAGVGT
LISMMLPYSAFFLIAWIALFCIWVFVLGLPVGPGAPTFYPAP

Sequences:

>Translated_522_residues
MSQTDTQRDGRFLRTVEWLGNMLPHPVTLFIIFIVLLLIASAAGAYFELSVPDPRPVGAKGRADDGLIHVVSLLDADGLI
KILTHTVKNFTGFAPLGTVLVSLLGVGIAEKSGLISALMRLLLTKSPRKLTTFMVVFTGILSNTASELGYVVLIPLSAII
FHSLGRHPLAGLAAAFAGVSGGYSANLFLGTIDPLLAGITQQAAQIIHPDYVVGPEANWFFMVASTFVIALIGYFVTEKI
VEPQLGPYQSDLSQEEKDIRHSNEITPLEYKGLIWAGVVFVALSALLAWSIVPADGILRHPETGLVSGSPFLKSIVVFIF
LLFALPGIVYGRVTRSLRGEQEVVNAMAESMSTLGLYLVIIFFAAQFVAFFNWTNIGQYIAVKGATFLKEVGLGGSVLFI
GFILICAFINLMIGSASAQWAVTAPIFVPMLMLAGYAPEVIQAAYRIGDSVTNIITPMMSYFGLIMATVIKYKKDAGVGT
LISMMLPYSAFFLIAWIALFCIWVFVLGLPVGPGAPTFYPAP
>Mature_521_residues
SQTDTQRDGRFLRTVEWLGNMLPHPVTLFIIFIVLLLIASAAGAYFELSVPDPRPVGAKGRADDGLIHVVSLLDADGLIK
ILTHTVKNFTGFAPLGTVLVSLLGVGIAEKSGLISALMRLLLTKSPRKLTTFMVVFTGILSNTASELGYVVLIPLSAIIF
HSLGRHPLAGLAAAFAGVSGGYSANLFLGTIDPLLAGITQQAAQIIHPDYVVGPEANWFFMVASTFVIALIGYFVTEKIV
EPQLGPYQSDLSQEEKDIRHSNEITPLEYKGLIWAGVVFVALSALLAWSIVPADGILRHPETGLVSGSPFLKSIVVFIFL
LFALPGIVYGRVTRSLRGEQEVVNAMAESMSTLGLYLVIIFFAAQFVAFFNWTNIGQYIAVKGATFLKEVGLGGSVLFIG
FILICAFINLMIGSASAQWAVTAPIFVPMLMLAGYAPEVIQAAYRIGDSVTNIITPMMSYFGLIMATVIKYKKDAGVGTL
ISMMLPYSAFFLIAWIALFCIWVFVLGLPVGPGAPTFYPAP

Specific function: Essential for aminobenzoyl-glutamate utilization. May transport aminobenzoyl-glutamate into the cell. Seems also to increase the sensitivity to low levels of aminobenzoyl-glutamate. Sufficient to confer aminobenzoyl-glutamate utilization phenotype [H]

COG id: COG2978

COG function: function code H; Putative p-aminobenzoyl-glutamate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87081879, Length=505, Percent_Identity=38.6138613861386, Blast_Score=351, Evalue=7e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004697
- InterPro:   IPR011540 [H]

Pfam domain/function: PF03806 ABG_transport [H]

EC number: NA

Molecular weight: Translated: 56212; Mature: 56081

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00019 ACTININ_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTDTQRDGRFLRTVEWLGNMLPHPVTLFIIFIVLLLIASAAGAYFELSVPDPRPVGAK
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCC
GRADDGLIHVVSLLDADGLIKILTHTVKNFTGFAPLGTVLVSLLGVGIAEKSGLISALMR
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHCCCCHHHHHHH
LLLTKSPRKLTTFMVVFTGILSNTASELGYVVLIPLSAIIFHSLGRHPLAGLAAAFAGVS
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
GGYSANLFLGTIDPLLAGITQQAAQIIHPDYVVGPEANWFFMVASTFVIALIGYFVTEKI
CCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
VEPQLGPYQSDLSQEEKDIRHSNEITPLEYKGLIWAGVVFVALSALLAWSIVPADGILRH
HCCCCCCCHHHHHHHHHHHHHCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PETGLVSGSPFLKSIVVFIFLLFALPGIVYGRVTRSLRGEQEVVNAMAESMSTLGLYLVI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IFFAAQFVAFFNWTNIGQYIAVKGATFLKEVGLGGSVLFIGFILICAFINLMIGSASAQW
HHHHHHHHHHHHHHCCCCHHEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCE
AVTAPIFVPMLMLAGYAPEVIQAAYRIGDSVTNIITPMMSYFGLIMATVIKYKKDAGVGT
EEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LISMMLPYSAFFLIAWIALFCIWVFVLGLPVGPGAPTFYPAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQTDTQRDGRFLRTVEWLGNMLPHPVTLFIIFIVLLLIASAAGAYFELSVPDPRPVGAK
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCC
GRADDGLIHVVSLLDADGLIKILTHTVKNFTGFAPLGTVLVSLLGVGIAEKSGLISALMR
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHCCCCHHHHHHH
LLLTKSPRKLTTFMVVFTGILSNTASELGYVVLIPLSAIIFHSLGRHPLAGLAAAFAGVS
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
GGYSANLFLGTIDPLLAGITQQAAQIIHPDYVVGPEANWFFMVASTFVIALIGYFVTEKI
CCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
VEPQLGPYQSDLSQEEKDIRHSNEITPLEYKGLIWAGVVFVALSALLAWSIVPADGILRH
HCCCCCCCHHHHHHHHHHHHHCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PETGLVSGSPFLKSIVVFIFLLFALPGIVYGRVTRSLRGEQEVVNAMAESMSTLGLYLVI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IFFAAQFVAFFNWTNIGQYIAVKGATFLKEVGLGGSVLFIGFILICAFINLMIGSASAQW
HHHHHHHHHHHHHHCCCCHHEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCE
AVTAPIFVPMLMLAGYAPEVIQAAYRIGDSVTNIITPMMSYFGLIMATVIKYKKDAGVGT
EEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LISMMLPYSAFFLIAWIALFCIWVFVLGLPVGPGAPTFYPAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9829935; 9097039; 9278503; 2825131; 7567469 [H]