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The map label for this gene is mtrR [H]

Identifier: 161870563

GI number: 161870563

Start: 1660326

End: 1660958

Strand: Direct

Name: mtrR [H]

Synonym: NMCC_1629

Alternate gene names: 161870563

Gene position: 1660326-1660958 (Clockwise)

Preceding gene: 161870559

Following gene: 161870565

Centisome position: 77.1

GC content: 51.82

Gene sequence:

>633_bases
ATGAGAAAAACCAAAACCGAAGCCTTGAAAACCAAAGAACACCTGATGCTTGCCGCCTTGGAAACCTTTTACCGCAAAGG
GATTGCGCGCACCTCGCTCAACGAAATCGCCCAAGCCGCCGGCGTAACGCGCGGCGCGCTCTATTGGCATTTCAAAAATA
AGGAAGACTTGTTCGACGCGCTGTTCCAACGTATCTGCGACGACATCGAAAACTGCATCGCGCAAGATGCCGAAGATGCC
GAAGGAGGGTCTTGGGCGGTATTCCGCCACACGCTGCTGCACTTTTTCGAGCGGCTGCAAAGCAACGACATCTACTACAA
ATTCCACAACATCCTGTTTTTAAAATGCGAACACACGGAACAAAACGCCGCCGTTATCGCCATTGCCCGCAAGCATCAGG
CAATCTGGCGCGAGAAAATTACCGCCGTTTTGACCGAAGCGGTGGAAAATCAGGATTTGGCTGACGATTTGGACAAGGAA
ACAGCGGTCATCTTCATCAAATCAACCTTGGACGGGCTGATTTGGCGGTGGTTCTCTTCCTGCGAACGTTTCGATTTGGG
CAAAACCGCCCCGCGCATCATCGGGATAATGATGGACAACTTGGAAAACCATCCCGACCTGCGCCGGAAATAA

Upstream 100 bases:

>100_bases
CTCAATTTCATGGGTTTCATTATACATACACGATTGCATGGTTACAAAGTCTTTTTTATAATCCGCCCTCATCAAACCGA
CCCGAAACGAAAACGCCATT

Downstream 100 bases:

>100_bases
TCAAGCCTTGGTAACAATGCCGTCTGAAACGAACAAACCCTTTCAGACGGCATCAAAATGACACAAAGCCTTCTTCTAAA
AATACATATTGAGACCTTTG

Product: TetR/AcrR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MRKTKTEALKTKEHLMLAALETFYRKGIARTSLNEIAQAAGVTRGALYWHFKNKEDLFDALFQRICDDIENCIAQDAEDA
EGGSWAVFRHTLLHFFERLQSNDIYYKFHNILFLKCEHTEQNAAVIAIARKHQAIWREKITAVLTEAVENQDLADDLDKE
TAVIFIKSTLDGLIWRWFSSCERFDLGKTAPRIIGIMMDNLENHPDLRRK

Sequences:

>Translated_210_residues
MRKTKTEALKTKEHLMLAALETFYRKGIARTSLNEIAQAAGVTRGALYWHFKNKEDLFDALFQRICDDIENCIAQDAEDA
EGGSWAVFRHTLLHFFERLQSNDIYYKFHNILFLKCEHTEQNAAVIAIARKHQAIWREKITAVLTEAVENQDLADDLDKE
TAVIFIKSTLDGLIWRWFSSCERFDLGKTAPRIIGIMMDNLENHPDLRRK
>Mature_210_residues
MRKTKTEALKTKEHLMLAALETFYRKGIARTSLNEIAQAAGVTRGALYWHFKNKEDLFDALFQRICDDIENCIAQDAEDA
EGGSWAVFRHTLLHFFERLQSNDIYYKFHNILFLKCEHTEQNAAVIAIARKHQAIWREKITAVLTEAVENQDLADDLDKE
TAVIFIKSTLDGLIWRWFSSCERFDLGKTAPRIIGIMMDNLENHPDLRRK

Specific function: Putative repressor of the mtrC gene. Controls the permeability of the cell envelope to hydrophobic compounds such as antibiotics and detergents [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786669, Length=207, Percent_Identity=33.8164251207729, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789664, Length=193, Percent_Identity=29.0155440414508, Blast_Score=95, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR013572
- InterPro:   IPR001647 [H]

Pfam domain/function: PF08361 TetR_C_2; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24374; Mature: 24374

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTKTEALKTKEHLMLAALETFYRKGIARTSLNEIAQAAGVTRGALYWHFKNKEDLFDA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHH
LFQRICDDIENCIAQDAEDAEGGSWAVFRHTLLHFFERLQSNDIYYKFHNILFLKCEHTE
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCC
QNAAVIAIARKHQAIWREKITAVLTEAVENQDLADDLDKETAVIFIKSTLDGLIWRWFSS
CCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHH
CERFDLGKTAPRIIGIMMDNLENHPDLRRK
HHHCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRKTKTEALKTKEHLMLAALETFYRKGIARTSLNEIAQAAGVTRGALYWHFKNKEDLFDA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHH
LFQRICDDIENCIAQDAEDAEGGSWAVFRHTLLHFFERLQSNDIYYKFHNILFLKCEHTE
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCC
QNAAVIAIARKHQAIWREKITAVLTEAVENQDLADDLDKETAVIFIKSTLDGLIWRWFSS
CCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHH
CERFDLGKTAPRIIGIMMDNLENHPDLRRK
HHHCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8196548 [H]