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The map label for this gene is argS [H]

Identifier: 161870367

GI number: 161870367

Start: 1434281

End: 1436026

Strand: Direct

Name: argS [H]

Synonym: NMCC_1411

Alternate gene names: 161870367

Gene position: 1434281-1436026 (Clockwise)

Preceding gene: 161870366

Following gene: 161870368

Centisome position: 66.6

GC content: 55.61

Gene sequence:

>1746_bases
TTGAATTTAACCGAAAGACCGAACTTCATGAACCTACATCAAACCGTCGAACACGAAGCCGCCGCCGCCTTTGCCGCCGC
AGGCATCGCCGACAGTCCCGTTGTTTTGCAGCCGACCAAAAATGCCGAACACGGCGATTTCCAAATCAACGGCGTGATGG
GTGCGGCGAAAAAAGCCAAACAAAACCCGCGCGAACTGGCGCAAAAGGTCGCCGACGCATTGGCAGGCAACGCCGTCATC
GAAAGCGCGGAAGTCGCCGGTCCCGGTTTTATCAACCTGCGCCTGCGCCCCGAATTTCTCGCGCAAAACATTCAGACGGC
CTTGAACGACGCACGTTTCGGCGTGGCAAAAACCGACAAACCGCAAACCGTCGTTATCGACTATTCTTCGCCCAATCTGG
CGAAGGAAATGCACGTCGGCCACCTGCGTTCCAGCATCATCGGCGACAGCATTTCGCGCGTGTTAGAATTTATGGGCAAT
ACCGTTATCCGTCAAAACCACGTCGGCGACTGGGGTACGCAGTTTGGCATGTTGGTCGCTTATTTGGTCGAGCAGCAAAA
AGACAATGCCGCGTTCGAGTTGGCGGATTTGGAGCAGTTTTACCGCGCCGCCAAAGTGCGCTTTGACGAAGACCCTGCCT
TTGCCGACACCGCACGCGAATACGTTGTGAAGCTGCAAGGCGGCGATGAAACCGTTTTGGCATTGTGGAAACAGTTTGTC
GATATTTCGCTCTCGCACGCCCAAGCCGTTTACGACACGCTGGGCTTGAAGCTGCGCCCTGAAGACGTGGCAGGCGAATC
GAAATACAACGACGATTTGCAAGCCGTGGTCGATGATTTGGTTCAAAAAGGCTTGGCGGTCGAAGACGACGGCGCGAAAG
TCGTGTTCTTGGACGAGTTTAAAAACAAAGAAGGCGAACCCGCCGCATTTATCGTGCAAAAACAAGGCGGCGGCTTCCTT
TATGCTTCCACCGATTTGGCGTGTCTGCGCTACCGTGTCGGCACGCTTCATGCCGACCGCCTGCTGTACGTCGTCGACCA
CCGCCAAGCCCTGCACTTTGAGCAACTCTTTACCACTTCACGCAAAGCCGGCTATCTGCCGGAAAACGTCGGCGCGGCAT
TTGTCGGCTTCGGCACGATGATGGGCAAAGACGGCAAACCGTTCAAAACACGCAGCGGCGACACCGTGAAACTGGTCGAT
CTGCTGACCGAAGCCGTCGAACGCGCCACCGCTTTGGTGAAAGAAAAAAATCCCGAATTGGGTGCAGACGAAGCGGCAAA
AATAGGCAAAACCGTCGGCATCGGCGCGGTCAAATACGCCGACTTGAGCAAAAACCGCACCAGCGATTATGTGTTCGACT
GGGACGCCATGCTCTCGTTTGAAGGCAACACCGCCCCCTATCTGCAATACGCCTACACCCGCGTGCAAAGCGTGTTCCGC
AAAGCAGGCGAATGGGATGCAAATGCGCCAACCGTTTTGACCGAACCGCTGGAAAAACAGCTTGCCGCCGAGCTGCTGAA
ATTTGAAGACGTACTGCAAAGCGTGGCGGACACGGCGTATCCGCACTACCTCGCCGCCTACCTCTATCAAATTGCGACCC
TGTTCAGCCGCTTCTACGAAGCCTGTCCGATACTCAAAGCCGAAGGCGCAAGCCGCAACAGCCGCCTGCAACTGGCAAAA
CTCACCGGCGACACGCTGAAACAAGGCTTGGATTTGCTGGGCATCGATGTGTTGGACGTAATGTAA

Upstream 100 bases:

>100_bases
CAAGTGTTCGACGTACCCGAACCCGAAACGCCGTAAACCGGCAGAAAAAGCGCACAATTCCTGTTTCTGCCGCATAAAAT
CTTTTAAAATACCGCCTGAT

Downstream 100 bases:

>100_bases
AACCGCACCGCCCGATTGCGGACAACAGCCTCGCCATCCTTATCCGAATCTGAAAAAAGCGGCGCGATACACCGTATCCG
CCGCCCCTCCCAAAATGCGA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MNLTERPNFMNLHQTVEHEAAAAFAAAGIADSPVVLQPTKNAEHGDFQINGVMGAAKKAKQNPRELAQKVADALAGNAVI
ESAEVAGPGFINLRLRPEFLAQNIQTALNDARFGVAKTDKPQTVVIDYSSPNLAKEMHVGHLRSSIIGDSISRVLEFMGN
TVIRQNHVGDWGTQFGMLVAYLVEQQKDNAAFELADLEQFYRAAKVRFDEDPAFADTAREYVVKLQGGDETVLALWKQFV
DISLSHAQAVYDTLGLKLRPEDVAGESKYNDDLQAVVDDLVQKGLAVEDDGAKVVFLDEFKNKEGEPAAFIVQKQGGGFL
YASTDLACLRYRVGTLHADRLLYVVDHRQALHFEQLFTTSRKAGYLPENVGAAFVGFGTMMGKDGKPFKTRSGDTVKLVD
LLTEAVERATALVKEKNPELGADEAAKIGKTVGIGAVKYADLSKNRTSDYVFDWDAMLSFEGNTAPYLQYAYTRVQSVFR
KAGEWDANAPTVLTEPLEKQLAAELLKFEDVLQSVADTAYPHYLAAYLYQIATLFSRFYEACPILKAEGASRNSRLQLAK
LTGDTLKQGLDLLGIDVLDVM

Sequences:

>Translated_581_residues
MNLTERPNFMNLHQTVEHEAAAAFAAAGIADSPVVLQPTKNAEHGDFQINGVMGAAKKAKQNPRELAQKVADALAGNAVI
ESAEVAGPGFINLRLRPEFLAQNIQTALNDARFGVAKTDKPQTVVIDYSSPNLAKEMHVGHLRSSIIGDSISRVLEFMGN
TVIRQNHVGDWGTQFGMLVAYLVEQQKDNAAFELADLEQFYRAAKVRFDEDPAFADTAREYVVKLQGGDETVLALWKQFV
DISLSHAQAVYDTLGLKLRPEDVAGESKYNDDLQAVVDDLVQKGLAVEDDGAKVVFLDEFKNKEGEPAAFIVQKQGGGFL
YASTDLACLRYRVGTLHADRLLYVVDHRQALHFEQLFTTSRKAGYLPENVGAAFVGFGTMMGKDGKPFKTRSGDTVKLVD
LLTEAVERATALVKEKNPELGADEAAKIGKTVGIGAVKYADLSKNRTSDYVFDWDAMLSFEGNTAPYLQYAYTRVQSVFR
KAGEWDANAPTVLTEPLEKQLAAELLKFEDVLQSVADTAYPHYLAAYLYQIATLFSRFYEACPILKAEGASRNSRLQLAK
LTGDTLKQGLDLLGIDVLDVM
>Mature_581_residues
MNLTERPNFMNLHQTVEHEAAAAFAAAGIADSPVVLQPTKNAEHGDFQINGVMGAAKKAKQNPRELAQKVADALAGNAVI
ESAEVAGPGFINLRLRPEFLAQNIQTALNDARFGVAKTDKPQTVVIDYSSPNLAKEMHVGHLRSSIIGDSISRVLEFMGN
TVIRQNHVGDWGTQFGMLVAYLVEQQKDNAAFELADLEQFYRAAKVRFDEDPAFADTAREYVVKLQGGDETVLALWKQFV
DISLSHAQAVYDTLGLKLRPEDVAGESKYNDDLQAVVDDLVQKGLAVEDDGAKVVFLDEFKNKEGEPAAFIVQKQGGGFL
YASTDLACLRYRVGTLHADRLLYVVDHRQALHFEQLFTTSRKAGYLPENVGAAFVGFGTMMGKDGKPFKTRSGDTVKLVD
LLTEAVERATALVKEKNPELGADEAAKIGKTVGIGAVKYADLSKNRTSDYVFDWDAMLSFEGNTAPYLQYAYTRVQSVFR
KAGEWDANAPTVLTEPLEKQLAAELLKFEDVLQSVADTAYPHYLAAYLYQIATLFSRFYEACPILKAEGASRNSRLQLAK
LTGDTLKQGLDLLGIDVLDVM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=594, Percent_Identity=37.3737373737374, Blast_Score=401, Evalue=1e-112,
Organism=Homo sapiens, GI197100773, Length=529, Percent_Identity=31.1909262759924, Blast_Score=211, Evalue=2e-54,
Organism=Escherichia coli, GI1788184, Length=578, Percent_Identity=57.7854671280277, Blast_Score=657, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=576, Percent_Identity=39.5833333333333, Blast_Score=376, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71985068, Length=537, Percent_Identity=41.1545623836127, Blast_Score=371, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17532153, Length=387, Percent_Identity=27.906976744186, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6320548, Length=569, Percent_Identity=32.5131810193322, Blast_Score=247, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6321883, Length=576, Percent_Identity=27.2569444444444, Blast_Score=227, Evalue=4e-60,
Organism=Drosophila melanogaster, GI18859963, Length=586, Percent_Identity=36.518771331058, Blast_Score=377, Evalue=1e-105,
Organism=Drosophila melanogaster, GI28571570, Length=601, Percent_Identity=28.2861896838602, Blast_Score=183, Evalue=3e-46,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 63778; Mature: 63778

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTERPNFMNLHQTVEHEAAAAFAAAGIADSPVVLQPTKNAEHGDFQINGVMGAAKKAK
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEEHHHHHHHC
QNPRELAQKVADALAGNAVIESAEVAGPGFINLRLRPEFLAQNIQTALNDARFGVAKTDK
CCHHHHHHHHHHHHHCCHHHCCHHCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCCC
PQTVVIDYSSPNLAKEMHVGHLRSSIIGDSISRVLEFMGNTVIRQNHVGDWGTQFGMLVA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHH
YLVEQQKDNAAFELADLEQFYRAAKVRFDEDPAFADTAREYVVKLQGGDETVLALWKQFV
HHHHHCCCCCCEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEEECCCCHHHHHHHHHHH
DISLSHAQAVYDTLGLKLRPEDVAGESKYNDDLQAVVDDLVQKGLAVEDDGAKVVFLDEF
HHHHHHHHHHHHHHCCEECCHHCCCCCCCCHHHHHHHHHHHHCCCEEECCCCEEEEEECC
KNKEGEPAAFIVQKQGGGFLYASTDLACLRYRVGTLHADRLLYVVDHRQALHFEQLFTTS
CCCCCCCEEEEEEECCCEEEEECCCHHHHHHHHCCEECCCEEEEECCHHHHHHHHHHHHC
RKAGYLPENVGAAFVGFGTMMGKDGKPFKTRSGDTVKLVDLLTEAVERATALVKEKNPEL
CCCCCCCHHCCHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCC
GADEAAKIGKTVGIGAVKYADLSKNRTSDYVFDWDAMLSFEGNTAPYLQYAYTRVQSVFR
CCHHHHHHCCHHCCCCEEECCCCCCCCCCEEEEEHHEEEECCCCCHHHHHHHHHHHHHHH
KAGEWDANAPTVLTEPLEKQLAAELLKFEDVLQSVADTAYPHYLAAYLYQIATLFSRFYE
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ACPILKAEGASRNSRLQLAKLTGDTLKQGLDLLGIDVLDVM
HCCCEECCCCCCCCCEEEEECCHHHHHCCHHHHCCHHHHCC
>Mature Secondary Structure
MNLTERPNFMNLHQTVEHEAAAAFAAAGIADSPVVLQPTKNAEHGDFQINGVMGAAKKAK
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEEHHHHHHHC
QNPRELAQKVADALAGNAVIESAEVAGPGFINLRLRPEFLAQNIQTALNDARFGVAKTDK
CCHHHHHHHHHHHHHCCHHHCCHHCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCCC
PQTVVIDYSSPNLAKEMHVGHLRSSIIGDSISRVLEFMGNTVIRQNHVGDWGTQFGMLVA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHH
YLVEQQKDNAAFELADLEQFYRAAKVRFDEDPAFADTAREYVVKLQGGDETVLALWKQFV
HHHHHCCCCCCEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEEECCCCHHHHHHHHHHH
DISLSHAQAVYDTLGLKLRPEDVAGESKYNDDLQAVVDDLVQKGLAVEDDGAKVVFLDEF
HHHHHHHHHHHHHHCCEECCHHCCCCCCCCHHHHHHHHHHHHCCCEEECCCCEEEEEECC
KNKEGEPAAFIVQKQGGGFLYASTDLACLRYRVGTLHADRLLYVVDHRQALHFEQLFTTS
CCCCCCCEEEEEEECCCEEEEECCCHHHHHHHHCCEECCCEEEEECCHHHHHHHHHHHHC
RKAGYLPENVGAAFVGFGTMMGKDGKPFKTRSGDTVKLVDLLTEAVERATALVKEKNPEL
CCCCCCCHHCCHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCC
GADEAAKIGKTVGIGAVKYADLSKNRTSDYVFDWDAMLSFEGNTAPYLQYAYTRVQSVFR
CCHHHHHHCCHHCCCCEEECCCCCCCCCCEEEEEHHEEEECCCCCHHHHHHHHHHHHHHH
KAGEWDANAPTVLTEPLEKQLAAELLKFEDVLQSVADTAYPHYLAAYLYQIATLFSRFYE
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ACPILKAEGASRNSRLQLAKLTGDTLKQGLDLLGIDVLDVM
HCCCEECCCCCCCCCEEEEECCHHHHHCCHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA