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The map label for this gene is pncB [H]

Identifier: 161870366

GI number: 161870366

Start: 1433008

End: 1434216

Strand: Direct

Name: pncB [H]

Synonym: NMCC_1410

Alternate gene names: 161870366

Gene position: 1433008-1434216 (Clockwise)

Preceding gene: 161870365

Following gene: 161870367

Centisome position: 66.55

GC content: 56.66

Gene sequence:

>1209_bases
ATGACCGGCATCATACATTCGCTGCTTGACACCGACCTCTACAAATTCACTATGCTGCAAGTGGTTCTGCACCAGTTTCC
GCAGACGCACAGCCTTTACGAATTCCGCTGCCGCAACGCCTCGACCGTCTATCCGCTTGCCGACATCAAGGAAGACTTGG
AAGCCGAACTCGACGCGCTCTGCCGGCTGCGCTTCACCCACGACGAACTCGGCTATCTGCGCTCCCTGCGTTTCATCAAA
AGCGACTTTGTCGATTATCTCGAACTCTTCCAGCTCCAACGCCGCTTTGTCGAAATCGGCACAGACGATAAAGACCGTCT
GAACATCCGTATCGAAGGTCCGATGATACAGGCGATGTTTTTTGAAATCTTCATCCTCGCCATTGTCAACGAACTTTACT
TCCGCCGGCTGGAAACCCCTGCCGTTATCGAAGAAGGTGAACGCCGGCTTCAAGCCAAAGCCGCGCGCCTCAAAGAAATC
GCCGCCGCACAAAACCCCGACGATCCGCCCTTCCTGATTTCCGACTTCGGCACGCGCCGCCGCTACAAGCTCGCGTGGCA
GGAACACGTCATCCGCACCCTGCTCGAAGCCGCCCCAAGCATCGTGCGCGGCACCAGCAATGTCTTTCTCGCCAAAAAAC
TCGGCATTACCCCCATCGGCACCATGGCGCACGAATTCCTCCAAGCCTTCCAGGCCCTCGACGTACGCCTGCGGAATTTC
CAAAAGGCCGCGCTCGAAAGCTGGGTGCACGAATACCGGGGCGATTTGGGCGTTGCCCTGACCGACGTTGTCGGTATGGA
TGCCTTCCTGCGCGATTTCGACCTCTATTTCGCCAAACTTTTCGACGGGCTGCGCCACGACAGCGGCGACCCTTACGTTT
GGGGCGACAAAGCCTACGCCCACTATCAAAAGCTCAAAATCGACAGCCGCACCAAAATGCTGACCTTCTCCGACGGGCTG
GACATCGAACGCTCTTGGGCATTGCACCAATATTTCAAAGACCGCTTCAAAACCGGCTTCGGCATCGGCACCAACCTCAC
CAACGATATGGGGCATACGCCCTTGAATATCGTCTTGAAACTGGTCGAATGCAACGGGCAGTCCGTCGCCAAGCTGTCCG
ACTCTCCGGGCAAAACCATGACCAACAACAGCACCTTCCTCGCCTACCTGCGCCAAGTGTTCGACGTACCCGAACCCGAA
ACGCCGTAA

Upstream 100 bases:

>100_bases
CATGAGGGGGCGCATTCAGACGGCATTTCCGGCACACGGGGCGGGCGCGATGTGTTCTAATACGCCCCAAGCCGCCACCA
AAAATCGGGAGACACGCCAT

Downstream 100 bases:

>100_bases
ACCGGCAGAAAAAGCGCACAATTCCTGTTTCTGCCGCATAAAATCTTTTAAAATACCGCCTGATTTGAATTTAACCGAAA
GACCGAACTTCATGAACCTA

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTGIIHSLLDTDLYKFTMLQVVLHQFPQTHSLYEFRCRNASTVYPLADIKEDLEAELDALCRLRFTHDELGYLRSLRFIK
SDFVDYLELFQLQRRFVEIGTDDKDRLNIRIEGPMIQAMFFEIFILAIVNELYFRRLETPAVIEEGERRLQAKAARLKEI
AAAQNPDDPPFLISDFGTRRRYKLAWQEHVIRTLLEAAPSIVRGTSNVFLAKKLGITPIGTMAHEFLQAFQALDVRLRNF
QKAALESWVHEYRGDLGVALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYVWGDKAYAHYQKLKIDSRTKMLTFSDGL
DIERSWALHQYFKDRFKTGFGIGTNLTNDMGHTPLNIVLKLVECNGQSVAKLSDSPGKTMTNNSTFLAYLRQVFDVPEPE
TP

Sequences:

>Translated_402_residues
MTGIIHSLLDTDLYKFTMLQVVLHQFPQTHSLYEFRCRNASTVYPLADIKEDLEAELDALCRLRFTHDELGYLRSLRFIK
SDFVDYLELFQLQRRFVEIGTDDKDRLNIRIEGPMIQAMFFEIFILAIVNELYFRRLETPAVIEEGERRLQAKAARLKEI
AAAQNPDDPPFLISDFGTRRRYKLAWQEHVIRTLLEAAPSIVRGTSNVFLAKKLGITPIGTMAHEFLQAFQALDVRLRNF
QKAALESWVHEYRGDLGVALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYVWGDKAYAHYQKLKIDSRTKMLTFSDGL
DIERSWALHQYFKDRFKTGFGIGTNLTNDMGHTPLNIVLKLVECNGQSVAKLSDSPGKTMTNNSTFLAYLRQVFDVPEPE
TP
>Mature_401_residues
TGIIHSLLDTDLYKFTMLQVVLHQFPQTHSLYEFRCRNASTVYPLADIKEDLEAELDALCRLRFTHDELGYLRSLRFIKS
DFVDYLELFQLQRRFVEIGTDDKDRLNIRIEGPMIQAMFFEIFILAIVNELYFRRLETPAVIEEGERRLQAKAARLKEIA
AAQNPDDPPFLISDFGTRRRYKLAWQEHVIRTLLEAAPSIVRGTSNVFLAKKLGITPIGTMAHEFLQAFQALDVRLRNFQ
KAALESWVHEYRGDLGVALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYVWGDKAYAHYQKLKIDSRTKMLTFSDGLD
IERSWALHQYFKDRFKTGFGIGTNLTNDMGHTPLNIVLKLVECNGQSVAKLSDSPGKTMTNNSTFLAYLRQVFDVPEPET
P

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=397, Percent_Identity=43.0730478589421, Blast_Score=323, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6324783, Length=411, Percent_Identity=31.1435523114355, Blast_Score=194, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 46327; Mature: 46195

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGIIHSLLDTDLYKFTMLQVVLHQFPQTHSLYEFRCRNASTVYPLADIKEDLEAELDAL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
CRLRFTHDELGYLRSLRFIKSDFVDYLELFQLQRRFVEIGTDDKDRLNIRIEGPMIQAMF
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHH
FEIFILAIVNELYFRRLETPAVIEEGERRLQAKAARLKEIAAAQNPDDPPFLISDFGTRR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCH
RYKLAWQEHVIRTLLEAAPSIVRGTSNVFLAKKLGITPIGTMAHEFLQAFQALDVRLRNF
HHHHHHHHHHHHHHHHHCHHHHCCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
QKAALESWVHEYRGDLGVALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYVWGDKAYA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHH
HYQKLKIDSRTKMLTFSDGLDIERSWALHQYFKDRFKTGFGIGTNLTNDMGHTPLNIVLK
HHHHHEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
LVECNGQSVAKLSDSPGKTMTNNSTFLAYLRQVFDVPEPETP
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TGIIHSLLDTDLYKFTMLQVVLHQFPQTHSLYEFRCRNASTVYPLADIKEDLEAELDAL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
CRLRFTHDELGYLRSLRFIKSDFVDYLELFQLQRRFVEIGTDDKDRLNIRIEGPMIQAMF
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHH
FEIFILAIVNELYFRRLETPAVIEEGERRLQAKAARLKEIAAAQNPDDPPFLISDFGTRR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCH
RYKLAWQEHVIRTLLEAAPSIVRGTSNVFLAKKLGITPIGTMAHEFLQAFQALDVRLRNF
HHHHHHHHHHHHHHHHHCHHHHCCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
QKAALESWVHEYRGDLGVALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYVWGDKAYA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHH
HYQKLKIDSRTKMLTFSDGLDIERSWALHQYFKDRFKTGFGIGTNLTNDMGHTPLNIVLK
HHHHHEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
LVECNGQSVAKLSDSPGKTMTNNSTFLAYLRQVFDVPEPETP
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA