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The map label for this gene is trpS [H]

Identifier: 161870339

GI number: 161870339

Start: 1402269

End: 1403279

Strand: Reverse

Name: trpS [H]

Synonym: NMCC_1383

Alternate gene names: 161870339

Gene position: 1403279-1402269 (Counterclockwise)

Preceding gene: 161870341

Following gene: 161870338

Centisome position: 65.17

GC content: 55.0

Gene sequence:

>1011_bases
ATGAGCAAAAAACGAGTTCTGACCGGCGTAACCACCACCGGCATCCCGCATCTGGGCAACTACGTCGGTGCTATCCGCCC
CGCCGTCCGCGCGGCGCAAAACCCTGATACCGAATCCTTCCTCTTCCTCGCCGATTACCACGGTATCATCAAATGCCACG
AGCCGGAGATGATTCACCAATCCACCCAAGCCGTTGCCGCCACTTGGCTTGCCTGCGGACTCGACCCCGAGCGCACCACC
TTCTACCGTCAAAGCGACATTCCCGAAGTGATGGAATTGAACTGGATTCTGACCTGCATCACCGCCAAGGGTTTGATGAA
CCGCGCCCACGCCTACAAAGCCGCCGTGCAGGCAAATGCGGAAAACGGGCAGGAAGACCCCGATTTCGGCGTGGAAATGG
GTTTGTTCAGCTATCCGATTCTGATGACCGCCGACATCCTTATGTTCAACGCCAACGAAGTCCCCGTCGGGCGCGACCAA
ATCCAACACGTCGAAATGGCGCGCGACATCGCCGGCCGCTTCAATCACCGCTTTAAAGAAATCTTTACCCTGCCCGAAGT
GAAAATCGACGAAAACGTCGAACTCTTGGTCGGTTTGGACGGACGCAAAATGTCCAAATCCTACGGCAACACCATTCCGC
TTTGGGAAAACGACAAAAAAACCCAAAAATCGGTCAACAAAATCATCACCAATATGAAAGAGCCGGGCGAGCCGAAACAG
CCCGACGAAAGCCCATTGTTTGAAATCTACAAAGCCTTCTCCACGCCGTCTGAAACCGCAGCGTTCACGCAAATGCTTGC
CGAAGGCTTGGCTTGGGGCGAGGCAAAAAAACTTTTGGCGGCGAAAATCAACGCCGAACTCGCCGAACCGCGCGAACGCT
ACAACGAGCTGACCGCCGACCCTTCGCAAATCGAAGAGATTTTGCAGGCAGGCGCGCAAAAAGCGCGTAAAGAAGCACGC
GAATTGTTGGACAAAGTACGCGATGCGGTCGGCATCCGCCCGTTGAAATAA

Upstream 100 bases:

>100_bases
ATGGAAAAGTCTGTTGTCGGCTGGATGTAGGTGGCAAATCGGGTATAATCGGCGCATCTTTTTCCCTTTCAGACGGCATT
GATGCCGCAAGGACATTTTT

Downstream 100 bases:

>100_bases
ACCCGATGCCGTCCGAACCTCTTAAAGGCTTGCCGGAACAAAACGTCGTCCGGCTGACCGGCAAGCATCCCAACGACTTG
GAAGCCGTCAGCGGCAAATG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSKKRVLTGVTTTGIPHLGNYVGAIRPAVRAAQNPDTESFLFLADYHGIIKCHEPEMIHQSTQAVAATWLACGLDPERTT
FYRQSDIPEVMELNWILTCITAKGLMNRAHAYKAAVQANAENGQEDPDFGVEMGLFSYPILMTADILMFNANEVPVGRDQ
IQHVEMARDIAGRFNHRFKEIFTLPEVKIDENVELLVGLDGRKMSKSYGNTIPLWENDKKTQKSVNKIITNMKEPGEPKQ
PDESPLFEIYKAFSTPSETAAFTQMLAEGLAWGEAKKLLAAKINAELAEPRERYNELTADPSQIEEILQAGAQKARKEAR
ELLDKVRDAVGIRPLK

Sequences:

>Translated_336_residues
MSKKRVLTGVTTTGIPHLGNYVGAIRPAVRAAQNPDTESFLFLADYHGIIKCHEPEMIHQSTQAVAATWLACGLDPERTT
FYRQSDIPEVMELNWILTCITAKGLMNRAHAYKAAVQANAENGQEDPDFGVEMGLFSYPILMTADILMFNANEVPVGRDQ
IQHVEMARDIAGRFNHRFKEIFTLPEVKIDENVELLVGLDGRKMSKSYGNTIPLWENDKKTQKSVNKIITNMKEPGEPKQ
PDESPLFEIYKAFSTPSETAAFTQMLAEGLAWGEAKKLLAAKINAELAEPRERYNELTADPSQIEEILQAGAQKARKEAR
ELLDKVRDAVGIRPLK
>Mature_335_residues
SKKRVLTGVTTTGIPHLGNYVGAIRPAVRAAQNPDTESFLFLADYHGIIKCHEPEMIHQSTQAVAATWLACGLDPERTTF
YRQSDIPEVMELNWILTCITAKGLMNRAHAYKAAVQANAENGQEDPDFGVEMGLFSYPILMTADILMFNANEVPVGRDQI
QHVEMARDIAGRFNHRFKEIFTLPEVKIDENVELLVGLDGRKMSKSYGNTIPLWENDKKTQKSVNKIITNMKEPGEPKQP
DESPLFEIYKAFSTPSETAAFTQMLAEGLAWGEAKKLLAAKINAELAEPRERYNELTADPSQIEEILQAGAQKARKEARE
LLDKVRDAVGIRPLK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=338, Percent_Identity=30.1775147928994, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI41352700, Length=186, Percent_Identity=39.247311827957, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1789786, Length=342, Percent_Identity=33.9181286549708, Blast_Score=182, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71982800, Length=343, Percent_Identity=30.0291545189504, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI71982793, Length=343, Percent_Identity=30.0291545189504, Blast_Score=139, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6320474, Length=350, Percent_Identity=30.2857142857143, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666151, Length=340, Percent_Identity=30.5882352941176, Blast_Score=154, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37569; Mature: 37438

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKRVLTGVTTTGIPHLGNYVGAIRPAVRAAQNPDTESFLFLADYHGIIKCHEPEMIHQ
CCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCHHHHH
STQAVAATWLACGLDPERTTFYRQSDIPEVMELNWILTCITAKGLMNRAHAYKAAVQANA
HHHHHHHHHHHHCCCCHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ENGQEDPDFGVEMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGRFNHRFKE
CCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IFTLPEVKIDENVELLVGLDGRKMSKSYGNTIPLWENDKKTQKSVNKIITNMKEPGEPKQ
HHCCCCCEECCCCEEEEECCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
PDESPLFEIYKAFSTPSETAAFTQMLAEGLAWGEAKKLLAAKINAELAEPRERYNELTAD
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
PSQIEEILQAGAQKARKEARELLDKVRDAVGIRPLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SKKRVLTGVTTTGIPHLGNYVGAIRPAVRAAQNPDTESFLFLADYHGIIKCHEPEMIHQ
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCHHHHH
STQAVAATWLACGLDPERTTFYRQSDIPEVMELNWILTCITAKGLMNRAHAYKAAVQANA
HHHHHHHHHHHHCCCCHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ENGQEDPDFGVEMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGRFNHRFKE
CCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IFTLPEVKIDENVELLVGLDGRKMSKSYGNTIPLWENDKKTQKSVNKIITNMKEPGEPKQ
HHCCCCCEECCCCEEEEECCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
PDESPLFEIYKAFSTPSETAAFTQMLAEGLAWGEAKKLLAAKINAELAEPRERYNELTAD
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
PSQIEEILQAGAQKARKEARELLDKVRDAVGIRPLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]