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The map label for this gene is yfbQ [C]

Identifier: 161870341

GI number: 161870341

Start: 1406206

End: 1407420

Strand: Reverse

Name: yfbQ [C]

Synonym: NMCC_1385

Alternate gene names: 161870341

Gene position: 1407420-1406206 (Counterclockwise)

Preceding gene: 161870342

Following gene: 161870339

Centisome position: 65.36

GC content: 53.09

Gene sequence:

>1215_bases
ATGGATAAATTTCCCAAGTCTGCAAAGCTCGATCACGTCTGTTACGACATACGCGGGCCGGTTCACAAAAAAGCCCTTCA
GTTGGAAGAGGAGGGCAATAAAATCCTTAAACTCAATATCGGCAACCCTGCGCCGTTCGGCTTTGAAGCCCCTGATGAAA
TCTTGGTCGATGTCATCCGCAACCTGCCGACTTCGCAAGGCTATTGCGATTCTAAAGGGCTGTATTCCGCCCGCAAAGCC
ATTGTTCACTACTATCAGACCAAAGGTTTGCGCGATATTACGGTTGATGATGTCTATATCGGCAACGGCGTGTCCGAGCT
GATTACGATGTCTATGCAGGCATTGCTCAACGACGGCGACGAAATCCTGATTCCCGCGCCCGACTACCCTTTGTGGACGG
CGGCGGCAACGCTTGCGGGCGGTACGGTACGCCATTATCTGTGCGACGAAGAAAACGGCTGGTTCCCCAACCTTGCCGAT
ATGGAAGCCAAAATCACGCCCAAAACCAAAGCCATCGTCGTCATCAATCCCAATAATCCGACAGGCGCGGTGTACAGCAG
GGAAATCCTGTTGGAAATCGCCGAACTGGCGCGCAAGCACGGTTTGATTATTTTCGCCGACGAGATTTACGATAAAATCC
TTTATGACGGCGCGGTTCACCACCACATCGCCGCGCTTGCCCCCGACCTTTTGACGGTAACGTTCAACGGTTTGTCCAAA
TCCTACCGCGTCGCCGGCTTCCGCCAAGGCTGGATGGTGCTCAACGGGCCGAAACATCACGCAAAAGGTTACATCGAGGG
TTTGGATATGCTCTCGTCCATGCGCTTGTGTGCCAATACGCCGATGCAGCACGCGATTCAGACGGCATTGGGCGGCTATC
AGAGCATTAACGAATTTATCCTGCCGGGCGGGCGGCTTTTGGAACAGCGCAACAGGGCGTGGGAACTGGTCAGCCAAATC
CCCGGCGTGTCCTGCGTCAAACCGATGGGCGCGATGTATATGTTCCCGAAAATCGATACCGAAATGTACCGCATCCGCGA
TGACATGAAATTCGTTTACGATTTGCTGGTGCGCGAAAAAGTCTTGCTGGTGCAGGGAACGGGGTTTAATTGGATTAAAC
CCGACCATTTCCGCATTGTTACGCTGCCTTACGTCCATCAGATTGAAGAGGCGATGGGCAGGCTGGCAAGATTCCTGCAA
ACCTACCGCCAATAA

Upstream 100 bases:

>100_bases
GAGGGCAGGTAAAAAGCCTGAAAATCTCGGTTTGATGCTTTAAATTCCGCGTGAAAAAGAGTACATTCCCACCCATTGCC
CAAAATTTACGGAACACATC

Downstream 100 bases:

>100_bases
GGGGACGGTTTGTCTGCCGAGGATAAAAAATGCCGTCTGAAACGGAGATTCCCGTTTCAGACGGCATTTTCAACAGCAGG
AACGAATCAGGCAAATTTCA

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MDKFPKSAKLDHVCYDIRGPVHKKALQLEEEGNKILKLNIGNPAPFGFEAPDEILVDVIRNLPTSQGYCDSKGLYSARKA
IVHYYQTKGLRDITVDDVYIGNGVSELITMSMQALLNDGDEILIPAPDYPLWTAAATLAGGTVRHYLCDEENGWFPNLAD
MEAKITPKTKAIVVINPNNPTGAVYSREILLEIAELARKHGLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTFNGLSK
SYRVAGFRQGWMVLNGPKHHAKGYIEGLDMLSSMRLCANTPMQHAIQTALGGYQSINEFILPGGRLLEQRNRAWELVSQI
PGVSCVKPMGAMYMFPKIDTEMYRIRDDMKFVYDLLVREKVLLVQGTGFNWIKPDHFRIVTLPYVHQIEEAMGRLARFLQ
TYRQ

Sequences:

>Translated_404_residues
MDKFPKSAKLDHVCYDIRGPVHKKALQLEEEGNKILKLNIGNPAPFGFEAPDEILVDVIRNLPTSQGYCDSKGLYSARKA
IVHYYQTKGLRDITVDDVYIGNGVSELITMSMQALLNDGDEILIPAPDYPLWTAAATLAGGTVRHYLCDEENGWFPNLAD
MEAKITPKTKAIVVINPNNPTGAVYSREILLEIAELARKHGLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTFNGLSK
SYRVAGFRQGWMVLNGPKHHAKGYIEGLDMLSSMRLCANTPMQHAIQTALGGYQSINEFILPGGRLLEQRNRAWELVSQI
PGVSCVKPMGAMYMFPKIDTEMYRIRDDMKFVYDLLVREKVLLVQGTGFNWIKPDHFRIVTLPYVHQIEEAMGRLARFLQ
TYRQ
>Mature_404_residues
MDKFPKSAKLDHVCYDIRGPVHKKALQLEEEGNKILKLNIGNPAPFGFEAPDEILVDVIRNLPTSQGYCDSKGLYSARKA
IVHYYQTKGLRDITVDDVYIGNGVSELITMSMQALLNDGDEILIPAPDYPLWTAAATLAGGTVRHYLCDEENGWFPNLAD
MEAKITPKTKAIVVINPNNPTGAVYSREILLEIAELARKHGLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTFNGLSK
SYRVAGFRQGWMVLNGPKHHAKGYIEGLDMLSSMRLCANTPMQHAIQTALGGYQSINEFILPGGRLLEQRNRAWELVSQI
PGVSCVKPMGAMYMFPKIDTEMYRIRDDMKFVYDLLVREKVLLVQGTGFNWIKPDHFRIVTLPYVHQIEEAMGRLARFLQ
TYRQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=385, Percent_Identity=28.8311688311688, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI19263340, Length=465, Percent_Identity=26.8817204301075, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=27.1739130434783, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4885351, Length=447, Percent_Identity=24.6085011185682, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI56713254, Length=227, Percent_Identity=28.6343612334802, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI56713256, Length=227, Percent_Identity=28.6343612334802, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI95147551, Length=172, Percent_Identity=31.9767441860465, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI169881279, Length=172, Percent_Identity=31.9767441860465, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI169881281, Length=128, Percent_Identity=33.59375, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=75.2475247524752, Blast_Score=657, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=378, Percent_Identity=29.1005291005291, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786816, Length=198, Percent_Identity=23.7373737373737, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787909, Length=212, Percent_Identity=24.0566037735849, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=406, Percent_Identity=30.5418719211823, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71981209, Length=464, Percent_Identity=25.6465517241379, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=205, Percent_Identity=32.1951219512195, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=205, Percent_Identity=32.1951219512195, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17567369, Length=239, Percent_Identity=29.7071129707113, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71981215, Length=294, Percent_Identity=27.2108843537415, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320317, Length=453, Percent_Identity=26.2693156732892, Blast_Score=126, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6323118, Length=349, Percent_Identity=27.5071633237822, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6322401, Length=363, Percent_Identity=24.2424242424242, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18859735, Length=378, Percent_Identity=28.3068783068783, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI45551451, Length=492, Percent_Identity=26.8292682926829, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24641770, Length=492, Percent_Identity=26.8292682926829, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24641760, Length=492, Percent_Identity=26.8292682926829, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24641768, Length=492, Percent_Identity=26.8292682926829, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24641766, Length=492, Percent_Identity=26.8292682926829, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24641764, Length=492, Percent_Identity=26.8292682926829, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28573069, Length=257, Percent_Identity=26.8482490272374, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24646114, Length=257, Percent_Identity=26.8482490272374, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28573067, Length=257, Percent_Identity=26.8482490272374, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28573065, Length=257, Percent_Identity=26.8482490272374, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45464; Mature: 45464

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFPKSAKLDHVCYDIRGPVHKKALQLEEEGNKILKLNIGNPAPFGFEAPDEILVDVIR
CCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTSQGYCDSKGLYSARKAIVHYYQTKGLRDITVDDVYIGNGVSELITMSMQALLNDGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCEEECCCHHHHHHHHHHHHHCCCC
EILIPAPDYPLWTAAATLAGGTVRHYLCDEENGWFPNLADMEAKITPKTKAIVVINPNNP
EEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEECCCCEEEEEEECCCC
TGAVYSREILLEIAELARKHGLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTFNGLSK
CCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCC
SYRVAGFRQGWMVLNGPKHHAKGYIEGLDMLSSMRLCANTPMQHAIQTALGGYQSINEFI
CCEECEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
LPGGRLLEQRNRAWELVSQIPGVSCVKPMGAMYMFPKIDTEMYRIRDDMKFVYDLLVREK
CCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCE
VLLVQGTGFNWIKPDHFRIVTLPYVHQIEEAMGRLARFLQTYRQ
EEEEECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKFPKSAKLDHVCYDIRGPVHKKALQLEEEGNKILKLNIGNPAPFGFEAPDEILVDVIR
CCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTSQGYCDSKGLYSARKAIVHYYQTKGLRDITVDDVYIGNGVSELITMSMQALLNDGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCEEECCCHHHHHHHHHHHHHCCCC
EILIPAPDYPLWTAAATLAGGTVRHYLCDEENGWFPNLADMEAKITPKTKAIVVINPNNP
EEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEECCCCEEEEEEECCCC
TGAVYSREILLEIAELARKHGLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTFNGLSK
CCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCC
SYRVAGFRQGWMVLNGPKHHAKGYIEGLDMLSSMRLCANTPMQHAIQTALGGYQSINEFI
CCEECEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
LPGGRLLEQRNRAWELVSQIPGVSCVKPMGAMYMFPKIDTEMYRIRDDMKFVYDLLVREK
CCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCE
VLLVQGTGFNWIKPDHFRIVTLPYVHQIEEAMGRLARFLQTYRQ
EEEEECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]