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The map label for this gene is dinP [H]

Identifier: 161870317

GI number: 161870317

Start: 1375342

End: 1376370

Strand: Reverse

Name: dinP [H]

Synonym: NMCC_1359

Alternate gene names: 161870317

Gene position: 1376370-1375342 (Counterclockwise)

Preceding gene: 161870318

Following gene: 229597118

Centisome position: 63.92

GC content: 57.43

Gene sequence:

>1029_bases
ATGGACGCATTCTACGCATCGGTAGAGCTGCGCGAACAGCCGCATTTGAAAGGGCGGCCGGTGGTCGTCGCGTGGGAGGG
CGCGCGTTCGGTGATTTGCGCCGCATCGTATGAGGCACGGCAGTTCGGGCTGCATTCCGCGATGTCGGTGGCAACGGCGA
AAAGGCTGTGTCCGCAAGCGGTGTATGTGCCGCCGCATTTCGATTTGTACCGTCAGGTTTCCGCGCAGATTCACGCCGTA
TTCAGGCGTTATACCGATTTAATCGAACCCTTGTCGCTGGACGAAGCCTATCTTGACGTTACCCGTAATTTCAAAAACAT
CCCTTACGCCAGCGAAGTTGCCAAAGAAATCCGTGCCGCCATTTTTGCGGAAACAGGTTTGACTGCATCCGCAGGCATCG
CGCCGAACAAATTTCTGGCGAAAATCGCGTCGGACTGGCGCAAGCCGAACGGGCAGTTTGTGTTGCCGCCGCACAAAGTC
ATGGCATTTTTGGAAACCCTGCCTTTGGGCAAAATCCCCGGCGTGGGCAAGGTAACGCTGAAAAAAATGCAGTCGCTGGG
TATGCGGACGGCGGGCGACTTGCGCCGTTTCGAGCGCGGCGAACTCTTAAACCATTTCGGACGCTACGGATACCGCCTCT
ATGATTTGGTGCGCGGTACGGATGAACGCCCCGTCAAAGCCGAACGCGAACGCCTCCAAATCTCCACAGAAATCACCCTG
CCTGAAGACCTGCCGCTCGAGCAGGCTGCCGGACACCTGCCCCATCTTGCTGAAGACCTGTGGCGGCAAATCACGCGCAA
AAACGTCGAAGCCCAAAGCGTAACGCTCAAGCTGAAGACCTACGATTTCCGCATCATCACGCGCACACTGACTTATTCCT
CCGTATTGCCCGACTGCGCAGCTCTGCTGCAGGCTGCGCAAATGTTGATAGCGCGCGTCCCGCCGCAGACGGAAGACGCG
TTCCGCCTTATCGGTATCGGCGTGGGGCATCTTGTGCCGAAAAACCAGCAGCAGGATTTGTGGGCGTAA

Upstream 100 bases:

>100_bases
TATCGGGGCGTATATTTGGAATTTGCCCGATGCCGGCAGTAGAATATCCCTTTTATCCTCAGAAGAGCCGATGTCTTCAC
GCAAAATTATCCACATCGAC

Downstream 100 bases:

>100_bases
ACCGCTTTACGCGCGCCGTCCAAAAAATATGCCGTCTGAAGCCTTCAGACGGCATTGCGGCTCCGGTTTAATCCGCCGCG
CCGCTTTTTTTTAGGTTGTC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MDAFYASVELREQPHLKGRPVVVAWEGARSVICAASYEARQFGLHSAMSVATAKRLCPQAVYVPPHFDLYRQVSAQIHAV
FRRYTDLIEPLSLDEAYLDVTRNFKNIPYASEVAKEIRAAIFAETGLTASAGIAPNKFLAKIASDWRKPNGQFVLPPHKV
MAFLETLPLGKIPGVGKVTLKKMQSLGMRTAGDLRRFERGELLNHFGRYGYRLYDLVRGTDERPVKAERERLQISTEITL
PEDLPLEQAAGHLPHLAEDLWRQITRKNVEAQSVTLKLKTYDFRIITRTLTYSSVLPDCAALLQAAQMLIARVPPQTEDA
FRLIGIGVGHLVPKNQQQDLWA

Sequences:

>Translated_342_residues
MDAFYASVELREQPHLKGRPVVVAWEGARSVICAASYEARQFGLHSAMSVATAKRLCPQAVYVPPHFDLYRQVSAQIHAV
FRRYTDLIEPLSLDEAYLDVTRNFKNIPYASEVAKEIRAAIFAETGLTASAGIAPNKFLAKIASDWRKPNGQFVLPPHKV
MAFLETLPLGKIPGVGKVTLKKMQSLGMRTAGDLRRFERGELLNHFGRYGYRLYDLVRGTDERPVKAERERLQISTEITL
PEDLPLEQAAGHLPHLAEDLWRQITRKNVEAQSVTLKLKTYDFRIITRTLTYSSVLPDCAALLQAAQMLIARVPPQTEDA
FRLIGIGVGHLVPKNQQQDLWA
>Mature_342_residues
MDAFYASVELREQPHLKGRPVVVAWEGARSVICAASYEARQFGLHSAMSVATAKRLCPQAVYVPPHFDLYRQVSAQIHAV
FRRYTDLIEPLSLDEAYLDVTRNFKNIPYASEVAKEIRAAIFAETGLTASAGIAPNKFLAKIASDWRKPNGQFVLPPHKV
MAFLETLPLGKIPGVGKVTLKKMQSLGMRTAGDLRRFERGELLNHFGRYGYRLYDLVRGTDERPVKAERERLQISTEITL
PEDLPLEQAAGHLPHLAEDLWRQITRKNVEAQSVTLKLKTYDFRIITRTLTYSSVLPDCAALLQAAQMLIARVPPQTEDA
FRLIGIGVGHLVPKNQQQDLWA

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=410, Percent_Identity=30, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI7706681, Length=411, Percent_Identity=29.9270072992701, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI154350220, Length=319, Percent_Identity=28.2131661442006, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI7705344, Length=204, Percent_Identity=35.7843137254902, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI5729982, Length=355, Percent_Identity=27.3239436619718, Blast_Score=112, Evalue=4e-25,
Organism=Escherichia coli, GI1786425, Length=245, Percent_Identity=50.2040816326531, Blast_Score=244, Evalue=5e-66,
Organism=Escherichia coli, GI1787432, Length=215, Percent_Identity=29.3023255813954, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193205700, Length=394, Percent_Identity=27.6649746192893, Blast_Score=134, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17537959, Length=368, Percent_Identity=26.9021739130435, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI193205702, Length=344, Percent_Identity=27.0348837209302, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115534089, Length=154, Percent_Identity=37.012987012987, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324921, Length=242, Percent_Identity=27.6859504132231, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19923006, Length=337, Percent_Identity=27.299703264095, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24668444, Length=302, Percent_Identity=27.8145695364238, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 38443; Mature: 38443

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAFYASVELREQPHLKGRPVVVAWEGARSVICAASYEARQFGLHSAMSVATAKRLCPQA
CCCEEEEEECCCCCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCE
VYVPPHFDLYRQVSAQIHAVFRRYTDLIEPLSLDEAYLDVTRNFKNIPYASEVAKEIRAA
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
IFAETGLTASAGIAPNKFLAKIASDWRKPNGQFVLPPHKVMAFLETLPLGKIPGVGKVTL
HHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHCCCCCCCCCCHHHH
KKMQSLGMRTAGDLRRFERGELLNHFGRYGYRLYDLVRGTDERPVKAERERLQISTEITL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEEEEEC
PEDLPLEQAAGHLPHLAEDLWRQITRKNVEAQSVTLKLKTYDFRIITRTLTYSSVLPDCA
CCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEEHHHHHHHHHHHHH
ALLQAAQMLIARVPPQTEDAFRLIGIGVGHLVPKNQQQDLWA
HHHHHHHHHHHHCCCCCCCHHHHHHCCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDAFYASVELREQPHLKGRPVVVAWEGARSVICAASYEARQFGLHSAMSVATAKRLCPQA
CCCEEEEEECCCCCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCE
VYVPPHFDLYRQVSAQIHAVFRRYTDLIEPLSLDEAYLDVTRNFKNIPYASEVAKEIRAA
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
IFAETGLTASAGIAPNKFLAKIASDWRKPNGQFVLPPHKVMAFLETLPLGKIPGVGKVTL
HHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHCCCCCCCCCCHHHH
KKMQSLGMRTAGDLRRFERGELLNHFGRYGYRLYDLVRGTDERPVKAERERLQISTEITL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEEEEEC
PEDLPLEQAAGHLPHLAEDLWRQITRKNVEAQSVTLKLKTYDFRIITRTLTYSSVLPDCA
CCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEEHHHHHHHHHHHHH
ALLQAAQMLIARVPPQTEDAFRLIGIGVGHLVPKNQQQDLWA
HHHHHHHHHHHHCCCCCCCHHHHHHCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA