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The map label for this gene is hscB [H]

Identifier: 161870256

GI number: 161870256

Start: 1298536

End: 1299036

Strand: Direct

Name: hscB [H]

Synonym: NMCC_1297

Alternate gene names: 161870256

Gene position: 1298536-1299036 (Clockwise)

Preceding gene: 161870255

Following gene: 161870257

Centisome position: 60.3

GC content: 52.69

Gene sequence:

>501_bases
ATGTCCCAATATTTCACCCTCTTCCGGATTGAACCCGCTTTCGATATCGACACCGAAAACTTGGAACAAACCTACCGCGC
CTTGGCCGCCCGTTTCCATCCCGATAAATTCGCTTCAGCTTCCGCCTTTGAGCAAAAGCAGGCAGTGATGATGTCTTCCA
CCATCAACGATGCCTACCGCACCTTGAAAAACCCCATCGACCGCGCCGCCTACCTGCTGAAAACATCGGGCATCGATGCC
GACGCGCCGGAGCATACCGCTTTCGCCCCCGAATTCCTTATGCAGCAAATGGAATGGCGCGAAACGCTGATGGAGGCACG
GGCAGGCAACGACCTTGAATCCTTGAAAAATCTCGACAACGAAATCCGCGACGAACAAGAAAAACTGTTCTGCGGTCTGA
AACAGTCGTTTGCCCGACAAGATTACGACACAGCCGCACAACAAGTCCGCCAAGGCAGGTTTCTCGACAAACTCCGCAAC
GAAATTTCCTCGGCATTATAA

Upstream 100 bases:

>100_bases
GCTGCACTTTGCCGCCCATATTCAGTCCTTTCGTTTAAGAAGCTGCAGATTATAAGGCAAAAACAGTTTTCTGCCAAAAT
CTTACATTTATCATCCTACT

Downstream 100 bases:

>100_bases
TCCGCACCGTGTTTCAGACGGCGTAACCGCCGCACCGTTCCGCGTCAAAATATGCTAAAATAAGCAACAATTTTTTGCCA
TACGAAACATTGAAACCATG

Product: molecular chaperone HscB (Hsc20)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MSQYFTLFRIEPAFDIDTENLEQTYRALAARFHPDKFASASAFEQKQAVMMSSTINDAYRTLKNPIDRAAYLLKTSGIDA
DAPEHTAFAPEFLMQQMEWRETLMEARAGNDLESLKNLDNEIRDEQEKLFCGLKQSFARQDYDTAAQQVRQGRFLDKLRN
EISSAL

Sequences:

>Translated_166_residues
MSQYFTLFRIEPAFDIDTENLEQTYRALAARFHPDKFASASAFEQKQAVMMSSTINDAYRTLKNPIDRAAYLLKTSGIDA
DAPEHTAFAPEFLMQQMEWRETLMEARAGNDLESLKNLDNEIRDEQEKLFCGLKQSFARQDYDTAAQQVRQGRFLDKLRN
EISSAL
>Mature_165_residues
SQYFTLFRIEPAFDIDTENLEQTYRALAARFHPDKFASASAFEQKQAVMMSSTINDAYRTLKNPIDRAAYLLKTSGIDAD
APEHTAFAPEFLMQQMEWRETLMEARAGNDLESLKNLDNEIRDEQEKLFCGLKQSFARQDYDTAAQQVRQGRFLDKLRNE
ISSAL

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=161, Percent_Identity=29.8136645962733, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1788876, Length=160, Percent_Identity=40.625, Blast_Score=108, Evalue=2e-25,
Organism=Drosophila melanogaster, GI161084223, Length=159, Percent_Identity=31.4465408805031, Blast_Score=83, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 19132; Mature: 19000

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQYFTLFRIEPAFDIDTENLEQTYRALAARFHPDKFASASAFEQKQAVMMSSTINDAYR
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLKNPIDRAAYLLKTSGIDADAPEHTAFAPEFLMQQMEWRETLMEARAGNDLESLKNLDN
HHHHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
EIRDEQEKLFCGLKQSFARQDYDTAAQQVRQGRFLDKLRNEISSAL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQYFTLFRIEPAFDIDTENLEQTYRALAARFHPDKFASASAFEQKQAVMMSSTINDAYR
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLKNPIDRAAYLLKTSGIDADAPEHTAFAPEFLMQQMEWRETLMEARAGNDLESLKNLDN
HHHHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
EIRDEQEKLFCGLKQSFARQDYDTAAQQVRQGRFLDKLRNEISSAL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA