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The map label for this gene is zur [H]

Identifier: 161870137

GI number: 161870137

Start: 1164760

End: 1165347

Strand: Reverse

Name: zur [H]

Synonym: NMCC_1176

Alternate gene names: 161870137

Gene position: 1165347-1164760 (Counterclockwise)

Preceding gene: 161870138

Following gene: 161870136

Centisome position: 54.12

GC content: 51.87

Gene sequence:

>588_bases
ATGCGGGCTGTCGGGCATTGTTGGAAAAGATTTCCAAATAAAGCAATTGAATACAAATATAAAACCGCCTCCTGCCGTAT
CGGTTGTTCAGACGGCATAAACAGAGAATTTATGAAAACAAATTTCAAACAGAAAATTATCGAACAGGCACGCAGCGAAG
GCTTGCAGGTAACCGCTTTGCGCGAGCAGGTATTAGATATTGTCTTGCAGCAAAGCGGCGTGATTAAAGCCTACAACGTC
TTGTCGCAGATGCAGCAGCAAAGCGAGGGCGTGCTTGCACCGCCTACCGCCTACCGCGCCCTTGATTTTTGGGCGGAGCA
GGGCGTTTTGCACAAAGTGGCGGCGGTCAACGGCTATATTTTGTGCAGCCACGCGCAGCACGAGTGCGACGACCATTGCC
ACGACCACGAAGAAGCCGAAGCGCACCACAGCGCGTTTATTTTGGTCTGCACCGAATGCGGCACGGCGGACGAGCAAACC
CTCAGCCACGAGTGGGCGGCACTGCGCGCAGGCGTTGCCGAAAGCGGCTTTGCGCTGAAAGAAGAACACGTTGTTTTAAC
TGGGATTTGTAAAAAATGTCAGAAATGA

Upstream 100 bases:

>100_bases
AAAATATTCAAGCTGACCGACCTGATACCCGAAAGCGGTTACGACCATGTCCCCGATCCGTGGTACACGGGCGATTTTGA
AGAAACCTTCAGGCTTGCGG

Downstream 100 bases:

>100_bases
AAAAAACCAAAGTCCACCTGATTTCAGGTTTTCTGGGAACAGGCAAAACCACCGCGCTCAAAAGCCTGATGGCGCAAAAA
GACCCGAACGAAAAATGGGT

Product: cation uptake regulator

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MRAVGHCWKRFPNKAIEYKYKTASCRIGCSDGINREFMKTNFKQKIIEQARSEGLQVTALREQVLDIVLQQSGVIKAYNV
LSQMQQQSEGVLAPPTAYRALDFWAEQGVLHKVAAVNGYILCSHAQHECDDHCHDHEEAEAHHSAFILVCTECGTADEQT
LSHEWAALRAGVAESGFALKEEHVVLTGICKKCQK

Sequences:

>Translated_195_residues
MRAVGHCWKRFPNKAIEYKYKTASCRIGCSDGINREFMKTNFKQKIIEQARSEGLQVTALREQVLDIVLQQSGVIKAYNV
LSQMQQQSEGVLAPPTAYRALDFWAEQGVLHKVAAVNGYILCSHAQHECDDHCHDHEEAEAHHSAFILVCTECGTADEQT
LSHEWAALRAGVAESGFALKEEHVVLTGICKKCQK
>Mature_195_residues
MRAVGHCWKRFPNKAIEYKYKTASCRIGCSDGINREFMKTNFKQKIIEQARSEGLQVTALREQVLDIVLQQSGVIKAYNV
LSQMQQQSEGVLAPPTAYRALDFWAEQGVLHKVAAVNGYILCSHAQHECDDHCHDHEEAEAHHSAFILVCTECGTADEQT
LSHEWAALRAGVAESGFALKEEHVVLTGICKKCQK

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=160, Percent_Identity=30.625, Blast_Score=81, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 21813; Mature: 21813

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVGHCWKRFPNKAIEYKYKTASCRIGCSDGINREFMKTNFKQKIIEQARSEGLQVTAL
CCHHHHHHHHCCCHHHEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEHHH
REQVLDIVLQQSGVIKAYNVLSQMQQQSEGVLAPPTAYRALDFWAEQGVLHKVAAVNGYI
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCEE
LCSHAQHECDDHCHDHEEAEAHHSAFILVCTECGTADEQTLSHEWAALRAGVAESGFALK
EECCCHHHHHHHHCCCHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEC
EEHVVLTGICKKCQK
CCCCHHHHHHHHHCC
>Mature Secondary Structure
MRAVGHCWKRFPNKAIEYKYKTASCRIGCSDGINREFMKTNFKQKIIEQARSEGLQVTAL
CCHHHHHHHHCCCHHHEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEHHH
REQVLDIVLQQSGVIKAYNVLSQMQQQSEGVLAPPTAYRALDFWAEQGVLHKVAAVNGYI
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCEE
LCSHAQHECDDHCHDHEEAEAHHSAFILVCTECGTADEQTLSHEWAALRAGVAESGFALK
EECCCHHHHHHHHCCCHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEC
EEHVVLTGICKKCQK
CCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]