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The map label for this gene is yfkJ [H]

Identifier: 161870138

GI number: 161870138

Start: 1165307

End: 1165762

Strand: Reverse

Name: yfkJ [H]

Synonym: NMCC_1177

Alternate gene names: 161870138

Gene position: 1165762-1165307 (Counterclockwise)

Preceding gene: 161870139

Following gene: 161870137

Centisome position: 54.14

GC content: 54.39

Gene sequence:

>456_bases
ATGAAAAAACCGAAAATCCTTTTTGTCTGCCTCGGCAACATCTGCCGTTCGCCGATGGCGGAATACATTTTGCGCCGCCG
CGCCGCCGAAGCGGGCATTCCCCTTGAAGCGGACAGCGCGGGGACATCGGGCTGGCACGACGGGGAAGATATGCACCGCG
AGACGGCAAAGATATTGAAAAAACACGGTATCGATGCTTCAGGCTTTACCAGCCGCAAAATCCGCCAAAGCGATGCGGCG
GCGTTTGACTGCATCATCGCGATGGACGGCAAGAATTTGTCCGAATTGGAAAGAACCTTCGGCAGGCGGCCGGAAAAAAT
ATTCAAGCTGACCGACCTGATACCCGAAAGCGGTTACGACCATGTCCCCGATCCGTGGTACACGGGCGATTTTGAAGAAA
CCTTCAGGCTTGCGGATGCGGGCTGTCGGGCATTGTTGGAAAAGATTTCCAAATAA

Upstream 100 bases:

>100_bases
GTTTTGGCTGGTTCTGCCTTATGCGGTTACGATTAACCGACCGATGACGTCTGAAAGGGTTTCCGCTTCAGACGGCATCG
CGCCGGAACAGGGAGGGGAT

Downstream 100 bases:

>100_bases
AGCAATTGAATACAAATATAAAACCGCCTCCTGCCGTATCGGTTGTTCAGACGGCATAAACAGAGAATTTATGAAAACAA
ATTTCAAACAGAAAATTATC

Product: low molecular weight protein tyrosine-phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKKPKILFVCLGNICRSPMAEYILRRRAAEAGIPLEADSAGTSGWHDGEDMHRETAKILKKHGIDASGFTSRKIRQSDAA
AFDCIIAMDGKNLSELERTFGRRPEKIFKLTDLIPESGYDHVPDPWYTGDFEETFRLADAGCRALLEKISK

Sequences:

>Translated_151_residues
MKKPKILFVCLGNICRSPMAEYILRRRAAEAGIPLEADSAGTSGWHDGEDMHRETAKILKKHGIDASGFTSRKIRQSDAA
AFDCIIAMDGKNLSELERTFGRRPEKIFKLTDLIPESGYDHVPDPWYTGDFEETFRLADAGCRALLEKISK
>Mature_151_residues
MKKPKILFVCLGNICRSPMAEYILRRRAAEAGIPLEADSAGTSGWHDGEDMHRETAKILKKHGIDASGFTSRKIRQSDAA
AFDCIIAMDGKNLSELERTFGRRPEKIFKLTDLIPESGYDHVPDPWYTGDFEETFRLADAGCRALLEKISK

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=150, Percent_Identity=38, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI6005988, Length=150, Percent_Identity=36, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6325330, Length=161, Percent_Identity=33.5403726708075, Blast_Score=80, Evalue=1e-16,
Organism=Drosophila melanogaster, GI78706766, Length=154, Percent_Identity=35.0649350649351, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI78706768, Length=154, Percent_Identity=35.0649350649351, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI78706770, Length=153, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI78706772, Length=153, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI78706764, Length=130, Percent_Identity=37.6923076923077, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI78711846, Length=151, Percent_Identity=33.7748344370861, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24648069, Length=96, Percent_Identity=38.5416666666667, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16932; Mature: 16932

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKPKILFVCLGNICRSPMAEYILRRRAAEAGIPLEADSAGTSGWHDGEDMHRETAKILK
CCCCCEEHEEHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KHGIDASGFTSRKIRQSDAAAFDCIIAMDGKNLSELERTFGRRPEKIFKLTDLIPESGYD
HHCCCCCCCCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCC
HVPDPWYTGDFEETFRLADAGCRALLEKISK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKPKILFVCLGNICRSPMAEYILRRRAAEAGIPLEADSAGTSGWHDGEDMHRETAKILK
CCCCCEEHEEHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KHGIDASGFTSRKIRQSDAAAFDCIIAMDGKNLSELERTFGRRPEKIFKLTDLIPESGYD
HHCCCCCCCCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCC
HVPDPWYTGDFEETFRLADAGCRALLEKISK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]