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The map label for this gene is hupB

Identifier: 161870073

GI number: 161870073

Start: 1096554

End: 1096823

Strand: Reverse

Name: hupB

Synonym: NMCC_1111

Alternate gene names: 161870073

Gene position: 1096823-1096554 (Counterclockwise)

Preceding gene: 161870074

Following gene: 161870070

Centisome position: 50.93

GC content: 52.96

Gene sequence:

>270_bases
GTGAACAAGTCTGAATTGATCGAAGCGATTGCTCAAGAAGCCGACATTTCCAAAGCCGCCGCACAAAAAGCTTTGGATGC
CACTACCAATGCAGTAACCACCGCCCTGAAACAAGGCGACACCGTTACTTTGGTCGGTTTCGGTACTTTCTACGTGGGCG
AACGTGCGGAACGCCAAGGCCGCAACCCCAAAACCGGCGAGCCTCTGACCATTGCCGCCGCCAAAACGCCTAAATTCCGT
GCAGGTAAAGCATTGAAAGACGCACTGTAA

Upstream 100 bases:

>100_bases
CGGCAATTTCAGAATTGCTATAAAGCGAAAGTTGCTCAAGCAGTACAAACCCCGAGTATTCGGGCATTTCATCATTTTTT
AAGACAGGAAGGGACTGATT

Downstream 100 bases:

>100_bases
GCCGTTTTTTATGAAAAAAGCCGATTCTTTAAAGAATCGGCTTTTTTATCGGTCCACATTATTCTGATTTCAAATCGGCA
ACACACTGCTTGTCACGTGC

Product: DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MNKSELIEAIAQEADISKAAAQKALDATTNAVTTALKQGDTVTLVGFGTFYVGERAERQGRNPKTGEPLTIAAAKTPKFR
AGKALKDAL

Sequences:

>Translated_89_residues
MNKSELIEAIAQEADISKAAAQKALDATTNAVTTALKQGDTVTLVGFGTFYVGERAERQGRNPKTGEPLTIAAAKTPKFR
AGKALKDAL
>Mature_89_residues
MNKSELIEAIAQEADISKAAAQKALDATTNAVTTALKQGDTVTLVGFGTFYVGERAERQGRNPKTGEPLTIAAAKTPKFR
AGKALKDAL

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=69.6629213483146, Blast_Score=121, Evalue=1e-29,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=58.4269662921348, Blast_Score=107, Evalue=1e-25,
Organism=Escherichia coli, GI1787141, Length=88, Percent_Identity=38.6363636363636, Blast_Score=69, Evalue=4e-14,
Organism=Escherichia coli, GI1788005, Length=86, Percent_Identity=36.046511627907, Blast_Score=62, Evalue=7e-12,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): DBHB_NEIMA (P64388)

Other databases:

- EMBL:   AL157959
- RefSeq:   YP_002342744.1
- ProteinModelPortal:   P64388
- SMR:   P64388
- EnsemblBacteria:   EBNEIT00000001700
- GeneID:   907799
- GenomeReviews:   AL157959_GR
- KEGG:   nma:NMA1397
- GeneTree:   EBGT00050000021325
- HOGENOM:   HBG705085
- OMA:   GIKDALC
- ProtClustDB:   CLSK877945
- BioCyc:   NMEN122587:NMA1397-MONOMER
- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 9348; Mature: 9348

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSELIEAIAQEADISKAAAQKALDATTNAVTTALKQGDTVTLVGFGTFYVGERAERQG
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHCCCHHHHCC
RNPKTGEPLTIAAAKTPKFRAGKALKDAL
CCCCCCCCEEEEECCCCCCCCCCHHHHCC
>Mature Secondary Structure
MNKSELIEAIAQEADISKAAAQKALDATTNAVTTALKQGDTVTLVGFGTFYVGERAERQG
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHCCCHHHHCC
RNPKTGEPLTIAAAKTPKFRAGKALKDAL
CCCCCCCCEEEEECCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919