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The map label for this gene is accA [H]

Identifier: 161870025

GI number: 161870025

Start: 1039487

End: 1040446

Strand: Direct

Name: accA [H]

Synonym: NMCC_1058

Alternate gene names: 161870025

Gene position: 1039487-1040446 (Clockwise)

Preceding gene: 161870023

Following gene: 161870026

Centisome position: 48.27

GC content: 53.75

Gene sequence:

>960_bases
ATGAAACCTGTTTTTTTGGATTTTGAACAACCCATAGCCGAACTGACCAACAAAATCGATGAGCTGCGTTTCGTCCAAGA
CGAGTCTGCCGTCGATATTTCGGACGAAATACACCGTTTGCAGAAAAAAAGCAACGACCTGACCAAATCGATTTTCAGCA
AACTTACGCCCGCCCAGGTTTCACAGGTTTCCCGGCATCCGCAGCGTCCCTATACTTTGGATTACATTGAGGCACTGTTT
ACTGATTTTGAAGAGCTGCACGGCGACCGCCACTTTGCCGACGATTATGCGATTGTCGGCGGATTGGCGCGTTTCAACGG
ACAAAGCGTGATGGTCGTCGGGCATCAGAAAGGGCGCGACACCAAAGAAAAAATCCGCCGCAACTTCGGTATGCCCCGTC
CTGAAGGCTACCGCAAAGCCCTGCGCCTGATGAAGACGGCAGAAAAATTCGGCTTGCCCGTCATGACCTTTATCGATACG
CCGGGCGCGTATCCCGGCATCGGCGCGGAAGAACGCGGGCAGTCGGAAGCCATCGGCAAAAACCTGTACGAACTGACGCG
CCTGCACGTCCCCGTTTTGTGTACCGTCATCGGCGAAGGGGGCTCGGGCGGTGCGTTGGCGGTCGCCGTAGGCGATTACG
TCAATATGCTGCAATACTCGACCTATTCCGTTATTTCCCCCGAAGGCTGCGCTTCGATTTTGTGGAAAACCGCCGAAAAG
GCGGCGGATGCGGCTCAGGCTTTGGGCATTACTGCCGACCGGCTGCAAAAGCTGGACTTGGTCGATACCGTCATCAAAGA
ACCATTGGGCGGCGCGCATCGGGATTTCGGGCAAACCATGAAAAACGTAAAAGCCGTTTTGGAAAAACAACTGCACGAAG
CGCAAAGCATCCCGCTTGCCGATTTGCTTTCGCGCCGTTTCGACCGCATTATGGCTTACGGCAAATTTTCGGAACAATAA

Upstream 100 bases:

>100_bases
AAGAGGGTGTGGAAAAGCCGTTTTGGACAATAAATTAACTGCGGAATATGCACAAATAGCGTATGATAGCGGCAGAATCT
GTTGATGAGAGCTTCATTCT

Downstream 100 bases:

>100_bases
TTCAGGTAGAACAAGCAGCAAGCAGTTTGTCTGAAACTGCTTGCTTTTTCTTTATCGGGGCGCGGCGTGCTGACTTTAGA
TGCGTTTGAGCAATGCTTGA

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MKPVFLDFEQPIAELTNKIDELRFVQDESAVDISDEIHRLQKKSNDLTKSIFSKLTPAQVSQVSRHPQRPYTLDYIEALF
TDFEELHGDRHFADDYAIVGGLARFNGQSVMVVGHQKGRDTKEKIRRNFGMPRPEGYRKALRLMKTAEKFGLPVMTFIDT
PGAYPGIGAEERGQSEAIGKNLYELTRLHVPVLCTVIGEGGSGGALAVAVGDYVNMLQYSTYSVISPEGCASILWKTAEK
AADAAQALGITADRLQKLDLVDTVIKEPLGGAHRDFGQTMKNVKAVLEKQLHEAQSIPLADLLSRRFDRIMAYGKFSEQ

Sequences:

>Translated_319_residues
MKPVFLDFEQPIAELTNKIDELRFVQDESAVDISDEIHRLQKKSNDLTKSIFSKLTPAQVSQVSRHPQRPYTLDYIEALF
TDFEELHGDRHFADDYAIVGGLARFNGQSVMVVGHQKGRDTKEKIRRNFGMPRPEGYRKALRLMKTAEKFGLPVMTFIDT
PGAYPGIGAEERGQSEAIGKNLYELTRLHVPVLCTVIGEGGSGGALAVAVGDYVNMLQYSTYSVISPEGCASILWKTAEK
AADAAQALGITADRLQKLDLVDTVIKEPLGGAHRDFGQTMKNVKAVLEKQLHEAQSIPLADLLSRRFDRIMAYGKFSEQ
>Mature_319_residues
MKPVFLDFEQPIAELTNKIDELRFVQDESAVDISDEIHRLQKKSNDLTKSIFSKLTPAQVSQVSRHPQRPYTLDYIEALF
TDFEELHGDRHFADDYAIVGGLARFNGQSVMVVGHQKGRDTKEKIRRNFGMPRPEGYRKALRLMKTAEKFGLPVMTFIDT
PGAYPGIGAEERGQSEAIGKNLYELTRLHVPVLCTVIGEGGSGGALAVAVGDYVNMLQYSTYSVISPEGCASILWKTAEK
AADAAQALGITADRLQKLDLVDTVIKEPLGGAHRDFGQTMKNVKAVLEKQLHEAQSIPLADLLSRRFDRIMAYGKFSEQ

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=313, Percent_Identity=64.5367412140575, Blast_Score=424, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 35460; Mature: 35460

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVFLDFEQPIAELTNKIDELRFVQDESAVDISDEIHRLQKKSNDLTKSIFSKLTPAQV
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHH
SQVSRHPQRPYTLDYIEALFTDFEELHGDRHFADDYAIVGGLARFNGQSVMVVGHQKGRD
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCC
TKEKIRRNFGMPRPEGYRKALRLMKTAEKFGLPVMTFIDTPGAYPGIGAEERGQSEAIGK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHH
NLYELTRLHVPVLCTVIGEGGSGGALAVAVGDYVNMLQYSTYSVISPEGCASILWKTAEK
HHHHHHHHHHHHHEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AADAAQALGITADRLQKLDLVDTVIKEPLGGAHRDFGQTMKNVKAVLEKQLHEAQSIPLA
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
DLLSRRFDRIMAYGKFSEQ
HHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKPVFLDFEQPIAELTNKIDELRFVQDESAVDISDEIHRLQKKSNDLTKSIFSKLTPAQV
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHH
SQVSRHPQRPYTLDYIEALFTDFEELHGDRHFADDYAIVGGLARFNGQSVMVVGHQKGRD
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCC
TKEKIRRNFGMPRPEGYRKALRLMKTAEKFGLPVMTFIDTPGAYPGIGAEERGQSEAIGK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHH
NLYELTRLHVPVLCTVIGEGGSGGALAVAVGDYVNMLQYSTYSVISPEGCASILWKTAEK
HHHHHHHHHHHHHEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AADAAQALGITADRLQKLDLVDTVIKEPLGGAHRDFGQTMKNVKAVLEKQLHEAQSIPLA
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
DLLSRRFDRIMAYGKFSEQ
HHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA