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The map label for this gene is fbp [H]

Identifier: 161869943

GI number: 161869943

Start: 977292

End: 978266

Strand: Reverse

Name: fbp [H]

Synonym: NMCC_0976

Alternate gene names: 161869943

Gene position: 978266-977292 (Counterclockwise)

Preceding gene: 161869944

Following gene: 161869940

Centisome position: 45.43

GC content: 53.74

Gene sequence:

>975_bases
ATGGACACACTGACCCGATTCCTCCCCGAACACCTGCAACAAAACCAGCTGCCCGAAGCACTCGGCGGCGTTTTACTGTC
CGTTGTTTCCGCCTGCACCGAAATCAACGCCAAAGTCCGCCTCGGCGCACTGGCCGGCGTATTGGGTATGACGGGCACGG
GCAATATTCAGGGCGAAGACCAAAAAAAACTGGATGTTATCGCCAACAACATCATGATTGACACACTCAAAGCCAACCCT
GCCGTTGCCGGTTTGGCAAGCGAGGAAGAAGACACTTTCGTAAGTGCCGGTGAAAACGGACGCTATCTCGTCCTATTCGA
CCCTTTAGACGGATCGTCCAATATTGATGTCAACATTTCCGTCGGTACGATTTTCTCCATCCTTGAAAAACCCGAAGGCG
CATTGGCAACCGAATCATTCCTTCAAACGGGTAGACAGCAGCTTGCCGCAGGCTATGTCCTCTACGGGCCTCAAACCCAG
CTCGTATTCACATTCGGACACGGCGTATATATGTTCACGCTCAATGCCGAAAACGAATTTGTGCTGACAAAAGAAAAACC
GAAAGTACCCGAAAGTACCAAAGAATTTGCCATCAATATGTCCAACCGCCGCCACTGGCTGCCCCCCGTCCAACAATACA
TCGACGAGCTCTTGGCGGGCGAAACCGGCACGCGCGGCAAAAACTACAATATGCGCTGGGTAGCCAGCATGGTTGCCGAA
ATCCACCGCATCCTGATGCGCGGCGGCGTGTTCATGTATCCGCAAGACAAACGCGACCCCGCCAAGCCCGGCAAACTGCG
CCTGATGTACGAAGCCAACCCTATGAGCCTGATACTCGAACAGGCGGGCGCATCGGCAAGCAACGCATATCAAGCCATGC
TCGACATACAGCCCGAAAACCTGCACCAACGCGTCGCCGTCTTCATGGGCAGCAGCGAAGAAGTGGATTACCTCAACCGC
CTGCATTCAAAATAA

Upstream 100 bases:

>100_bases
CTACAATCCCCTAGACTATCCTGCAAAACGCACCAAAGGAATACGCCACAATAACCTGCCGCCTTTCAGACGGCACAAAC
CTTTCCGAAACGAGCAAACT

Downstream 100 bases:

>100_bases
AAGGCAGCCTGACCGATAAAGAAAGGCGGCAGCGCGCATCCGACGCTGCCGCCGATATTTCGTTTATAGCCTTAAAAAGA
TAGAAAACCACCTTTCCGAA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MDTLTRFLPEHLQQNQLPEALGGVLLSVVSACTEINAKVRLGALAGVLGMTGTGNIQGEDQKKLDVIANNIMIDTLKANP
AVAGLASEEEDTFVSAGENGRYLVLFDPLDGSSNIDVNISVGTIFSILEKPEGALATESFLQTGRQQLAAGYVLYGPQTQ
LVFTFGHGVYMFTLNAENEFVLTKEKPKVPESTKEFAINMSNRRHWLPPVQQYIDELLAGETGTRGKNYNMRWVASMVAE
IHRILMRGGVFMYPQDKRDPAKPGKLRLMYEANPMSLILEQAGASASNAYQAMLDIQPENLHQRVAVFMGSSEEVDYLNR
LHSK

Sequences:

>Translated_324_residues
MDTLTRFLPEHLQQNQLPEALGGVLLSVVSACTEINAKVRLGALAGVLGMTGTGNIQGEDQKKLDVIANNIMIDTLKANP
AVAGLASEEEDTFVSAGENGRYLVLFDPLDGSSNIDVNISVGTIFSILEKPEGALATESFLQTGRQQLAAGYVLYGPQTQ
LVFTFGHGVYMFTLNAENEFVLTKEKPKVPESTKEFAINMSNRRHWLPPVQQYIDELLAGETGTRGKNYNMRWVASMVAE
IHRILMRGGVFMYPQDKRDPAKPGKLRLMYEANPMSLILEQAGASASNAYQAMLDIQPENLHQRVAVFMGSSEEVDYLNR
LHSK
>Mature_324_residues
MDTLTRFLPEHLQQNQLPEALGGVLLSVVSACTEINAKVRLGALAGVLGMTGTGNIQGEDQKKLDVIANNIMIDTLKANP
AVAGLASEEEDTFVSAGENGRYLVLFDPLDGSSNIDVNISVGTIFSILEKPEGALATESFLQTGRQQLAAGYVLYGPQTQ
LVFTFGHGVYMFTLNAENEFVLTKEKPKVPESTKEFAINMSNRRHWLPPVQQYIDELLAGETGTRGKNYNMRWVASMVAE
IHRILMRGGVFMYPQDKRDPAKPGKLRLMYEANPMSLILEQAGASASNAYQAMLDIQPENLHQRVAVFMGSSEEVDYLNR
LHSK

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI22907028, Length=324, Percent_Identity=40.1234567901235, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI189083692, Length=328, Percent_Identity=39.0243902439024, Blast_Score=221, Evalue=5e-58,
Organism=Homo sapiens, GI16579888, Length=328, Percent_Identity=39.0243902439024, Blast_Score=221, Evalue=5e-58,
Organism=Escherichia coli, GI1790679, Length=330, Percent_Identity=43.3333333333333, Blast_Score=248, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI17508131, Length=319, Percent_Identity=39.4984326018809, Blast_Score=223, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6323409, Length=321, Percent_Identity=38.3177570093458, Blast_Score=223, Evalue=4e-59,
Organism=Drosophila melanogaster, GI45550998, Length=321, Percent_Identity=40.809968847352, Blast_Score=220, Evalue=8e-58,
Organism=Drosophila melanogaster, GI19921562, Length=321, Percent_Identity=40.809968847352, Blast_Score=220, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 35667; Mature: 35667

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLTRFLPEHLQQNQLPEALGGVLLSVVSACTEINAKVRLGALAGVLGMTGTGNIQGED
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCCCCCCC
QKKLDVIANNIMIDTLKANPAVAGLASEEEDTFVSAGENGRYLVLFDPLDGSSNIDVNIS
HHHHHHHHCCEEEEEECCCCCEEECCCCCCCCEEECCCCCCEEEEEECCCCCCCEEEEEE
VGTIFSILEKPEGALATESFLQTGRQQLAAGYVLYGPQTQLVFTFGHGVYMFTLNAENEF
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEECCCEEEEEEECCCEEEEEECCCCCE
VLTKEKPKVPESTKEFAINMSNRRHWLPPVQQYIDELLAGETGTRGKNYNMRWVASMVAE
EEECCCCCCCCCCHHHEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
IHRILMRGGVFMYPQDKRDPAKPGKLRLMYEANPMSLILEQAGASASNAYQAMLDIQPEN
HHHHHHHCCEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCCCCEEEEEECCHHH
LHQRVAVFMGSSEEVDYLNRLHSK
HHHHHHHEECCCCCHHHHHHHHCC
>Mature Secondary Structure
MDTLTRFLPEHLQQNQLPEALGGVLLSVVSACTEINAKVRLGALAGVLGMTGTGNIQGED
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCCCCCCC
QKKLDVIANNIMIDTLKANPAVAGLASEEEDTFVSAGENGRYLVLFDPLDGSSNIDVNIS
HHHHHHHHCCEEEEEECCCCCEEECCCCCCCCEEECCCCCCEEEEEECCCCCCCEEEEEE
VGTIFSILEKPEGALATESFLQTGRQQLAAGYVLYGPQTQLVFTFGHGVYMFTLNAENEF
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEECCCEEEEEEECCCEEEEEECCCCCE
VLTKEKPKVPESTKEFAINMSNRRHWLPPVQQYIDELLAGETGTRGKNYNMRWVASMVAE
EEECCCCCCCCCCHHHEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
IHRILMRGGVFMYPQDKRDPAKPGKLRLMYEANPMSLILEQAGASASNAYQAMLDIQPEN
HHHHHHHCCEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCCCCEEEEEECCHHH
LHQRVAVFMGSSEEVDYLNRLHSK
HHHHHHHEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA