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The map label for this gene is cysW [H]

Identifier: 161869813

GI number: 161869813

Start: 844913

End: 845773

Strand: Reverse

Name: cysW [H]

Synonym: NMCC_0842

Alternate gene names: 161869813

Gene position: 845773-844913 (Counterclockwise)

Preceding gene: 161869814

Following gene: 161869812

Centisome position: 39.28

GC content: 56.91

Gene sequence:

>861_bases
ATGAAACCCTATTCCGCCAATCCCAACCTGACCGAACCGCGCTGGCTGCGCGTGTTGCTGATTGCCGCCGCGCTGGGCTT
TCTGCTGCTGATGCTGGTCGTGCCGCTCGTCGCCGTGTTTTACGAAGCCTTAAAAGGCGGTTGGGATTTGTACCTGAAAT
CCTTAAACGATCCCGAAGCGTGGTCTGCCATCAAATTGACGCTGATTACCGCGCTGATTGTCGTCCCCGTCAATGCCGTC
TTGGGCGTGGCGATGGCGTGGCTGCTGACCCGTTTTGATTTTCGCGGCAAGCAGTTGCTGACTACCCTGCTCGATTTGCC
GTTTTCCGTATCGCCCGTGGTGGCCGGTTTAATGTTCGTCTTATTGTTCGGCGCGCACACGGCATTGGGTGGCTGGCTCG
AAGCGCAAGGCATACAGATTATCTTCGCCATCCCCGGCATTATTCTGGCGACGCTGTTCGTTACTTTCCCCTTTGTCGCA
CGCGAAATCATCCCGCTGATGCAGGCTCAGGGCGACAGCGAAGAACAGGCGGCATTGATACTCGGCGCAAGCGGCTGGCA
GATGTTTTGGCGCGTTACCCTGCCCAACATCAAATGGGCGTTACTCTACGGCATCATCCTCACCAACGCCCGCGCGATGG
GCGAGTTCGGCGCGGTCAGCGTGGTATCGGGACACATACGCGGCGAAACCAACACCGTCCCGCTTTTGGTCGAAATCTTC
TACAACGAATACAACTTCACCGGCGCATTCGCCCTCTCCGGCGTATTGGCACTTTTAGCACTGGCGACGCTGGCGGTGCA
GAACATCATCACCAAATTACAAGACAAAAAACTCGCCGCCGCCGAAAGGAACGCAGCATGA

Upstream 100 bases:

>100_bases
TCAATAAAAGGTTGTCTGAAAACGAATCCGCCCCACAAAAAACGGTTTTTCAGACGGCATCCGAACACCTTAAAACAACC
AACCGGGGAACACCACCGCC

Downstream 100 bases:

>100_bases
GCATTACTATTCAAAATCTAAATAAACACTTCGGAGCGTTCCACGCGCTGAAAAACATCAACCTCAACGTCCCCACCGGC
AAACTCGTTTCCCTACTCGG

Product: sulphate permease inner membrane protein

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKPYSANPNLTEPRWLRVLLIAAALGFLLLMLVVPLVAVFYEALKGGWDLYLKSLNDPEAWSAIKLTLITALIVVPVNAV
LGVAMAWLLTRFDFRGKQLLTTLLDLPFSVSPVVAGLMFVLLFGAHTALGGWLEAQGIQIIFAIPGIILATLFVTFPFVA
REIIPLMQAQGDSEEQAALILGASGWQMFWRVTLPNIKWALLYGIILTNARAMGEFGAVSVVSGHIRGETNTVPLLVEIF
YNEYNFTGAFALSGVLALLALATLAVQNIITKLQDKKLAAAERNAA

Sequences:

>Translated_286_residues
MKPYSANPNLTEPRWLRVLLIAAALGFLLLMLVVPLVAVFYEALKGGWDLYLKSLNDPEAWSAIKLTLITALIVVPVNAV
LGVAMAWLLTRFDFRGKQLLTTLLDLPFSVSPVVAGLMFVLLFGAHTALGGWLEAQGIQIIFAIPGIILATLFVTFPFVA
REIIPLMQAQGDSEEQAALILGASGWQMFWRVTLPNIKWALLYGIILTNARAMGEFGAVSVVSGHIRGETNTVPLLVEIF
YNEYNFTGAFALSGVLALLALATLAVQNIITKLQDKKLAAAERNAA
>Mature_286_residues
MKPYSANPNLTEPRWLRVLLIAAALGFLLLMLVVPLVAVFYEALKGGWDLYLKSLNDPEAWSAIKLTLITALIVVPVNAV
LGVAMAWLLTRFDFRGKQLLTTLLDLPFSVSPVVAGLMFVLLFGAHTALGGWLEAQGIQIIFAIPGIILATLFVTFPFVA
REIIPLMQAQGDSEEQAALILGASGWQMFWRVTLPNIKWALLYGIILTNARAMGEFGAVSVVSGHIRGETNTVPLLVEIF
YNEYNFTGAFALSGVLALLALATLAVQNIITKLQDKKLAAAERNAA

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=287, Percent_Identity=49.8257839721254, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI1788764, Length=210, Percent_Identity=36.6666666666667, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1786980, Length=225, Percent_Identity=32.4444444444444, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31079; Mature: 31079

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPYSANPNLTEPRWLRVLLIAAALGFLLLMLVVPLVAVFYEALKGGWDLYLKSLNDPEA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHH
WSAIKLTLITALIVVPVNAVLGVAMAWLLTRFDFRGKQLLTTLLDLPFSVSPVVAGLMFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHH
LLFGAHTALGGWLEAQGIQIIFAIPGIILATLFVTFPFVAREIIPLMQAQGDSEEQAALI
HHHHHHHHHCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
LGASGWQMFWRVTLPNIKWALLYGIILTNARAMGEFGAVSVVSGHIRGETNTVPLLVEIF
EECCCCEEEEEEECCCCHHHHHHHHHHHCCHHHCCCCCHHHHCCCCCCCCCCHHHHHEEH
YNEYNFTGAFALSGVLALLALATLAVQNIITKLQDKKLAAAERNAA
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKPYSANPNLTEPRWLRVLLIAAALGFLLLMLVVPLVAVFYEALKGGWDLYLKSLNDPEA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHH
WSAIKLTLITALIVVPVNAVLGVAMAWLLTRFDFRGKQLLTTLLDLPFSVSPVVAGLMFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHH
LLFGAHTALGGWLEAQGIQIIFAIPGIILATLFVTFPFVAREIIPLMQAQGDSEEQAALI
HHHHHHHHHCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
LGASGWQMFWRVTLPNIKWALLYGIILTNARAMGEFGAVSVVSGHIRGETNTVPLLVEIF
EECCCCEEEEEEECCCCHHHHHHHHHHHCCHHHCCCCCHHHHCCCCCCCCCCHHHHHEEH
YNEYNFTGAFALSGVLALLALATLAVQNIITKLQDKKLAAAERNAA
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]