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The map label for this gene is engA [H]

Identifier: 161869787

GI number: 161869787

Start: 821491

End: 823101

Strand: Reverse

Name: engA [H]

Synonym: NMCC_0810

Alternate gene names: 161869787

Gene position: 823101-821491 (Counterclockwise)

Preceding gene: 161869788

Following gene: 161869786

Centisome position: 38.22

GC content: 53.2

Gene sequence:

>1611_bases
ATGCCGTCTGAAATGCTGTCCATTATTTATCAGACGACATTTTACCCTCCCTCTTTATGGCCTCTTGCCGTGAAGAACCT
ATTTACCGTGTCCAACGGACACCTGCTCGTGTTCAGTTCTCCCGAACGGCACTTGACACAGAAAGACCCAATAATGAAAC
CCACCATCGCGCTTGTCGGCCGCCCTAACGTCGGCAAATCTACTTTATTCAACCGTTTGACGCGCACCAAAGACGCACTC
GTACACGACCTGCCCGGCCTGACCCGCGACCGCCATTACGGACACGGCAAAGTCGGCAGCAAACCTTATTTGGTCATCGA
TACCGGAGGTTTCGAGCCGGTTGTGGACAGCGGCATTTTGCACGAAATGGCAAAACAAACCTTGCAGGCTGTCGATGAAG
CTGATGCGGTTGTGTTTTTGGTGGACGGCCGTACCGGCCTGACCCCGCAAGACAAAATCATTGCCGACCGCCTGCGCCAA
AGCCCGCGCCCTGTTTATCTGGCGGTAAACAAAGGCGAAGGCGGCAACAGGGCCGTGCTTGCCGCCGAGTTCTACGAACT
TGCTTTGGGCGACCCTTATGTTATTTCAGGTGCGCACGGCGATGGCGTGTATTATCTGATTGAAGATATTTTGGAAACCT
TCCCAGAGCCGGAAGCCGAAGAAGCCGATGCAAAACATCCCGTCTTTGCCGTCATCGGCCGTCCGAACGTCGGCAAATCC
ACACTGGTTAACGCCATCCTCGGCGAAGAGCGCGTGATTGCTTTCGATATGGCAGGCACGACACGCGACAGCATCCACAT
CGATTTCGAACGCGAAGGCAAACCGTTTACCATCATCGATACCGCAGGCGTGCGCCGTCGCGGCAAAGTGGATGAAGCAG
TAGAAAAATTCTCCGTTATCAAAGCGATGCAGGCGGTTGAAGCGGCAAACGTCGCTGTTTTGGTATTGGACGCGCAGCAG
GACATCGCCGACCAAGATGCGACGATTGCAGGTTTCGCTTTGGAGGCAGGCCGTGCTTTGGTGGTGGCGGTCAATAAATG
GGACGGCATCAGCGAAGAACGTCGCGAGCAAGTGAAACGCGATATCAACCGCAAACTGTATTTCCTTGATTTTGCTAAAT
TCCACTTTATTTCCGCGTTGAAAGAACGCGGCATAGACGGATTGTTCGACAGCATTCAGGCTGCCTACAACGCGGCAATG
ATTAAGATGCCGACGCCGAAAATCACGCGCGTACTGCAAAGCGCGATCGAACGTCAGCAACCGCCGCGTGCCGGCTTGGT
GCGTCCGAAAATGCGTTATGCCCACCAAGGCGGCATGAATCCGCCGGTGATTGTGGTACACGGCAATTCGCTGCACGCGA
TTTCCGACAGCTATACGCGCTACCTGACCCAAACGTTCCGCAAAGCCTTCAATCTGCAAGGTACGCCGTTGCGGATTCAA
TACAATGTTTCGGAAAACCCGTATGAAAATGCGGAAGACAAACCGAAGAAAAAACCGCTGCGCCGCGTCAGCCTGAGCAA
CCGTATTGAGAAACGCGAAGGCCGCAAAGAAGAGAAAAACCGCTTCAAGAAGAAAACCAAAGTCAGTGTGAAAAAACAAT
TCAGCAAATAA

Upstream 100 bases:

>100_bases
CCAGGAAGCCTTAAAAAACTACGGACAGGCTTTAGAAAAAATGCCTCAAGATTCTGTCGGTCGCGAATTGGTTCAAATGA
AACTTGATTCGCTGAAATAA

Downstream 100 bases:

>100_bases
TTCCCGACATTTCAAACAATAGGAAACATTATGTGGTTCAAGCAGATTAGTTTTTATCCGCTCAACAAAGAAAAGCTGCC
TGAGGCGGACGCACTTGCCG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 536; Mature: 535

Protein sequence:

>536_residues
MPSEMLSIIYQTTFYPPSLWPLAVKNLFTVSNGHLLVFSSPERHLTQKDPIMKPTIALVGRPNVGKSTLFNRLTRTKDAL
VHDLPGLTRDRHYGHGKVGSKPYLVIDTGGFEPVVDSGILHEMAKQTLQAVDEADAVVFLVDGRTGLTPQDKIIADRLRQ
SPRPVYLAVNKGEGGNRAVLAAEFYELALGDPYVISGAHGDGVYYLIEDILETFPEPEAEEADAKHPVFAVIGRPNVGKS
TLVNAILGEERVIAFDMAGTTRDSIHIDFEREGKPFTIIDTAGVRRRGKVDEAVEKFSVIKAMQAVEAANVAVLVLDAQQ
DIADQDATIAGFALEAGRALVVAVNKWDGISEERREQVKRDINRKLYFLDFAKFHFISALKERGIDGLFDSIQAAYNAAM
IKMPTPKITRVLQSAIERQQPPRAGLVRPKMRYAHQGGMNPPVIVVHGNSLHAISDSYTRYLTQTFRKAFNLQGTPLRIQ
YNVSENPYENAEDKPKKKPLRRVSLSNRIEKREGRKEEKNRFKKKTKVSVKKQFSK

Sequences:

>Translated_536_residues
MPSEMLSIIYQTTFYPPSLWPLAVKNLFTVSNGHLLVFSSPERHLTQKDPIMKPTIALVGRPNVGKSTLFNRLTRTKDAL
VHDLPGLTRDRHYGHGKVGSKPYLVIDTGGFEPVVDSGILHEMAKQTLQAVDEADAVVFLVDGRTGLTPQDKIIADRLRQ
SPRPVYLAVNKGEGGNRAVLAAEFYELALGDPYVISGAHGDGVYYLIEDILETFPEPEAEEADAKHPVFAVIGRPNVGKS
TLVNAILGEERVIAFDMAGTTRDSIHIDFEREGKPFTIIDTAGVRRRGKVDEAVEKFSVIKAMQAVEAANVAVLVLDAQQ
DIADQDATIAGFALEAGRALVVAVNKWDGISEERREQVKRDINRKLYFLDFAKFHFISALKERGIDGLFDSIQAAYNAAM
IKMPTPKITRVLQSAIERQQPPRAGLVRPKMRYAHQGGMNPPVIVVHGNSLHAISDSYTRYLTQTFRKAFNLQGTPLRIQ
YNVSENPYENAEDKPKKKPLRRVSLSNRIEKREGRKEEKNRFKKKTKVSVKKQFSK
>Mature_535_residues
PSEMLSIIYQTTFYPPSLWPLAVKNLFTVSNGHLLVFSSPERHLTQKDPIMKPTIALVGRPNVGKSTLFNRLTRTKDALV
HDLPGLTRDRHYGHGKVGSKPYLVIDTGGFEPVVDSGILHEMAKQTLQAVDEADAVVFLVDGRTGLTPQDKIIADRLRQS
PRPVYLAVNKGEGGNRAVLAAEFYELALGDPYVISGAHGDGVYYLIEDILETFPEPEAEEADAKHPVFAVIGRPNVGKST
LVNAILGEERVIAFDMAGTTRDSIHIDFEREGKPFTIIDTAGVRRRGKVDEAVEKFSVIKAMQAVEAANVAVLVLDAQQD
IADQDATIAGFALEAGRALVVAVNKWDGISEERREQVKRDINRKLYFLDFAKFHFISALKERGIDGLFDSIQAAYNAAMI
KMPTPKITRVLQSAIERQQPPRAGLVRPKMRYAHQGGMNPPVIVVHGNSLHAISDSYTRYLTQTFRKAFNLQGTPLRIQY
NVSENPYENAEDKPKKKPLRRVSLSNRIEKREGRKEEKNRFKKKTKVSVKKQFSK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=480, Percent_Identity=48.3333333333333, Blast_Score=469, Evalue=1e-133,
Organism=Escherichia coli, GI1788919, Length=116, Percent_Identity=37.9310344827586, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI2367268, Length=88, Percent_Identity=40.9090909090909, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 59806; Mature: 59675

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSEMLSIIYQTTFYPPSLWPLAVKNLFTVSNGHLLVFSSPERHLTQKDPIMKPTIALVG
CCHHHHHHHHHHCCCCCCCHHHHHHHHEEECCCEEEEECCCHHHCCCCCCCCCCCEEEEE
RPNVGKSTLFNRLTRTKDALVHDLPGLTRDRHYGHGKVGSKPYLVIDTGGFEPVVDSGIL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
HEMAKQTLQAVDEADAVVFLVDGRTGLTPQDKIIADRLRQSPRPVYLAVNKGEGGNRAVL
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCEEEE
AAEFYELALGDPYVISGAHGDGVYYLIEDILETFPEPEAEEADAKHPVFAVIGRPNVGKS
EEHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHH
TLVNAILGEERVIAFDMAGTTRDSIHIDFEREGKPFTIIDTAGVRRRGKVDEAVEKFSVI
HHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHH
KAMQAVEAANVAVLVLDAQQDIADQDATIAGFALEAGRALVVAVNKWDGISEERREQVKR
HHHHHHHHCCEEEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHH
DINRKLYFLDFAKFHFISALKERGIDGLFDSIQAAYNAAMIKMPTPKITRVLQSAIERQQ
HHCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHCC
PPRAGLVRPKMRYAHQGGMNPPVIVVHGNSLHAISDSYTRYLTQTFRKAFNLQGTPLRIQ
CCCCCCCCHHHHHHHCCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHCCCCCCEEEE
YNVSENPYENAEDKPKKKPLRRVSLSNRIEKREGRKEEKNRFKKKTKVSVKKQFSK
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSEMLSIIYQTTFYPPSLWPLAVKNLFTVSNGHLLVFSSPERHLTQKDPIMKPTIALVG
CHHHHHHHHHHCCCCCCCHHHHHHHHEEECCCEEEEECCCHHHCCCCCCCCCCCEEEEE
RPNVGKSTLFNRLTRTKDALVHDLPGLTRDRHYGHGKVGSKPYLVIDTGGFEPVVDSGIL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
HEMAKQTLQAVDEADAVVFLVDGRTGLTPQDKIIADRLRQSPRPVYLAVNKGEGGNRAVL
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCEEEE
AAEFYELALGDPYVISGAHGDGVYYLIEDILETFPEPEAEEADAKHPVFAVIGRPNVGKS
EEHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHH
TLVNAILGEERVIAFDMAGTTRDSIHIDFEREGKPFTIIDTAGVRRRGKVDEAVEKFSVI
HHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHH
KAMQAVEAANVAVLVLDAQQDIADQDATIAGFALEAGRALVVAVNKWDGISEERREQVKR
HHHHHHHHCCEEEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHH
DINRKLYFLDFAKFHFISALKERGIDGLFDSIQAAYNAAMIKMPTPKITRVLQSAIERQQ
HHCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHCC
PPRAGLVRPKMRYAHQGGMNPPVIVVHGNSLHAISDSYTRYLTQTFRKAFNLQGTPLRIQ
CCCCCCCCHHHHHHHCCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHCCCCCCEEEE
YNVSENPYENAEDKPKKKPLRRVSLSNRIEKREGRKEEKNRFKKKTKVSVKKQFSK
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10655208 [H]